CN105994305A

CN105994305A - Emulsion-in-water sterilizing composition and preparation method thereof

Info

Publication number: CN105994305A
Application number: CN201610337199.6A
Authority: CN
Inventors: 林王强
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-21
Filing date: 2016-05-21
Publication date: 2016-10-12

Abstract

The invention discloses an emulsion-in-water sterilizing composition and a preparation method thereof. The emulsion-in-water sterilizing composition contains phenylate diazole, aureonucleomycin and tetramycin. The sterilizing composition has good preventing and controlling effect on common lawn grass disease; ingredients are synergistic, so that prevention effect is enhanced remarkably; the ingredients are little in damage to human health and environment-friendly.

Description

A kind of aqueous emulsion bactericidal composition and preparation method thereof

Technical field

The invention belongs to agriculture chemicals fungicide field, be specifically related to a kind of microbicide compositions containing difenodiconazole, gold alloy hydride and tetramycin and preparation method thereof.

Background technology

Difenodiconazole (Difenodiconazole), chemical name: 2-[2-chloro-4(4-chlorobenzene oxygen) phenyl]-1, double (the 1H-1 of 3-, 2,4-triazol-1-yl)-2-propanol, belong to triazole bactericidal agent, it is possible to the plant disease that the multiple pathogenic fungi such as preventing and treating Botrytis, interlink spore genus, Verticillium cause.

Gold alloy hydride (Aureonucleomycin), is a kind of microbial source fungicide of Shanghai Pesticide Research Institute exploitation, and the disease causing various bacteria has the preventing effectiveness of excellence, and safe for human and animal and environment.

Tetramycin (Tetramycin), it it is a kind of microbial source fungicide, by not absorbing water, streptomycin Wuzhou subspecies produce, and the multiple known pathogenic fungi such as mastigomycetes, ascomycetes and Deuteromycotina fungus are had extremely strong killing action, especially to fruit tree putrefaction disease, spot defoliation；Cotton yellow (withered) withers disease；Root rot；Rice sheath blight disease, seedling blight；Radix Ginseng and Alternaria panax；Folium Camelliae sinensis gall of tea；Fruit white rot of grape, watermelon grafting etc. has specially good effect.

Turfgrass is the important component part of urban afforestation, Landscape, and Turfgrass Diseases not only affects attractive in appearance, and it is healthy that irrational prevention and controls also can affect civic, is required for turfgrass and proposes efficient, the antibacterial of low toxicity.At present, for purposes such as expanding prevention spectrums, the technology that pesticide activity components different to the mechanism of action, controlling object compounds use is widely used, but, the physicochemical property of different activities composition, action character are different, inappropriate compound scheme not only will not play its original biological activity, may cause the adverse consequences such as poisoning, harm environment on the contrary.Therefore, how selecting suitable active component to carry out the most compounding is a still problem in exploration.

Summary of the invention

For the problems referred to above, the invention provides a kind of safe and effective bactericidal composition, by difenodiconazole, gold alloy hydride and three kinds of fungicide active ingredients of tetramycin are applied in combination, can be the most collaborative between each component, compared with single component, biological activity is obviously enhanced, and low toxicity, to human health safety.

The invention provides a kind of microbicide compositions, including difenodiconazole, gold alloy hydride and tetramycin, wherein the weight ratio of difenodiconazole, gold alloy hydride and tetramycin is 1-80:1-40:1-60；It is preferably 1-60:1-20:1-40；More preferably: 1-10:1-6:1-8.

Microbicide compositions of the present invention can be prepared as the dosage form that agriculture field is conventional, comprise the most acceptable auxiliary agent kind accordingly, being preferably prepared to aqueous emulsion, microemulsion, water dispersible granules, wettable powder or suspending agent, preparation method is the conventional method in agriculture field.

For aqueous emulsion, the auxiliary agent adapted has: one or more in agriculture breast 600#, agriculture breast 400#, emulsifying agent T-60, TX-10, NPE, sorbester p18 # of emulsifying agent；Solvent is selected from dimethylbenzene, toluene, Ketohexamethylene, vegetable oil, hydrogenated vegetable oil；Stabilizer is selected from triphenyl phosphite, epoxychloropropane, acetic anhydride；Thickening agent is selected from bentonite, xanthan gum, aluminium-magnesium silicate, polyvinyl alcohol；Preservative is selected from sodium benzoate, potassium sorbate；One or more in ethylene glycol, glycerol, propylene glycol, glycerol, carbamide, sodium chloride of antifreezing agent.

For microemulsion, the auxiliary agent adapted has: one or more in calcium dodecyl benzene sulfonate, Nongru-700 #, agriculture breast 2201#, Arlacel-60 #, tween 80, TX-10, agriculture breast 400# of emulsifying agent；Cosolvent is selected from methanol, ethanol, isopropanol, n-butyl alcohol；Solvent is selected from Ketohexamethylene, dimethylbenzene, toluene, N-Methyl pyrrolidone；Stabilizer is selected from epoxychloropropane, triphenyl phosphite.

For water dispersible granules, the auxiliary agent adapted has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting agent is selected from alkyl sulfate, alkylsulfonate, polyoxyethylene alcohol；Disintegrating agent is selected from carbamide, ammonium sulfate, sucrose, citric acid, sodium bicarbonate；Binding agent is selected from kieselguhr, PVA, microcrystalline Cellulose；Filler is selected from kieselguhr, attapulgite, potter's clay, white carbon, Kaolin etc..

For wettable powder, the auxiliary agent adapted has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting agent is selected from dodecyl sodium sulfate, naphthalene sulfonate etc.；Fillers selection Kaolin, fine particle calcium carbonate, Pulvis Talci, attapulgite, potter's clay etc..

The bactericidal composition that the present invention provides can produce following beneficial effect:

(1) can produce synergism, compositions is significantly better than single component to the preventive effect of turfgrass Common Diseases and is used alone, and especially creeping bentgrass tail spore leaf spot and the brown cecospora spot of Festuca Arundinacea is had specially good effect；

(2) compositions contains two kinds of microbial source fungicides, low toxicity, environmentally friendly, it is suitable in urban afforestation, Landscape using.

Detailed description of the invention

By following example, the present invention is described in detail, but is not intended to limit the scope of the present invention.

Embodiment 1 aqueous emulsion

Raw material forms: difenodiconazole 3.5%, gold alloy hydride 1.5%, tetramycin 2.5%, agriculture breast 600# 4%, agriculture breast 400# 7%, dimethylbenzene 46%, triphenyl phosphite 4%, bentonite 0.3%, sodium benzoate 0.2%, glycerol 2%, deionized water supplies surplus, difenodiconazole, gold alloy hydride, tetramycin, agriculture breast 600#, agriculture breast 400# mix homogeneously are become oil phase, deionized water, dimethylbenzene, triphenyl phosphite, bentonite, sodium benzoate, glycerol are mixed into homogeneous aqueous phase, under high-speed stirred, aqueous phase is added oil phase, prepare described aqueous emulsion.

Embodiment 2 aqueous emulsion

Raw material forms: difenodiconazole 8%, gold alloy hydride 0.5%, tetramycin 2%, NPE 5%, agriculture breast 600#3.5%, soybean oil 42%, acetic anhydride 2.5%, xanthan gum 0.2%, sodium benzoate 0.5%, carbamide 3%, deionized water supplies surplus, prepare oil phase, aqueous phase respectively, under high velocity agitation aqueous phase is added oil phase, prepare described aqueous emulsion.

Embodiment 3 microemulsion

Raw material forms: difenodiconazole 5%, gold alloy hydride 2%, tetramycin 3%, agriculture breast 2201# 4%, TX-10 2.5%, Tween 80 2.5%, epoxychloropropane 2%, methanol 20%, Ketohexamethylene 25%, xanthan gum 0.6%, potassium sorbate 0.45%, deionized water supplies 100%, prepare oil phase, aqueous phase the most respectively, and oil phase added in aqueous phase be sufficiently mixed, fully emulsified through high speed shear, obtain product.

Embodiment 4 microemulsion

Raw material forms: difenodiconazole 8%, gold alloy hydride 0.2%, tetramycin 1.6%, Nongru-700 #8%, Arlacel-60 #4%, tween 80 2%, methanol 18%, dimethylbenzene 22%, epoxychloropropane 1.5%, deionized water supplies 100%, prepare oil phase, aqueous phase the most respectively, and oil phase added in aqueous phase be sufficiently mixed, fully emulsified through high speed shear, obtain product.

Embodiment 5 water dispersible granules

Raw material forms: difenodiconazole 24%, gold alloy hydride 0.8%, tetramycin 2%, polycarboxylate 8%, lignosulfonates 4.5%, polyoxyethylene alcohol 9.5%, ammonium sulfate 3.5%, kieselguhr 8.5%, attapulgite supply surplus, by said components through high speed shear mix homogeneously, the particle diameter needed is obtained through comminution by gas stream, quantitatively send into fluidized bed granulation the most dried, prepare described water dispersible granules product.

Embodiment 6 water dispersible granules

Raw material forms: difenodiconazole 15%, gold alloy hydride 0.9%, tetramycin 1.2%, lignosulfonates 5%, alkyl sulfate 4%, citric acid 5.5%, microcrystalline Cellulose 6.5%, Kaolin supply surplus, by said components through high speed shear mix homogeneously, the particle diameter needed is obtained through comminution by gas stream, quantitatively send into fluidized bed granulation the most dried, prepare described water dispersible granules product.

Embodiment 7 wettable powder

Raw material forms: difenodiconazole 9%, gold alloy hydride 2%, tetramycin 4%, polycarboxylate 5.5%, lignosulfonates 1.5%, dodecyl sodium sulfate 3.5%, Kaolin supply surplus, each raw material mixed pulverizer pulverize, enter jet mill fully to pulverize, be mixed to prepare described wettable powder.

Embodiment 8 wettable powder

Raw material forms: surplus supplied by difenodiconazole 12%, gold alloy hydride 3%, tetramycin 7%, lignosulfonates 3.5%, alkylnaphthalene sulfonate 2.5%, naphthalene sulfonate 5%, Pulvis Talci, each raw material mixed pulverizer pulverize, enter jet mill fully to pulverize, be mixed to prepare described wettable powder.

Comparative example 1: difenodiconazole 7%, gold alloy hydride 3%, is prepared as aqueous emulsion according to the method for embodiment 1.

Comparative example 2: gold alloy hydride 3%, tetramycin 5%, is prepared as aqueous emulsion according to the method for embodiment 1.

Comparative example 3: difenodiconazole 7%, tetramycin 5%, is prepared as aqueous emulsion according to the method for embodiment 1.

Experimental example 1

Preventing and treating creeping bentgrass tail spore leaf spot

Select the creeping bentgrass lawn that morbidity is serious, random division homalographic community, each process repeats three communities, carry out dispenser in the morning, 7 days are once, altogether dispenser 3 times, in last dispenser 10 days, 15 days, check the state of an illness and calculate preventive effect after 20 days, with clear water as blank, during test, lawn is avoided pruning, applying fertilizer.

The table 1 preventive effect to creeping bentgrass tail spore leaf spot

As can be seen from Table 1, the bactericidal composition that the present invention provides has notable preventive effect to creeping bentgrass tail spore leaf spot, and prevention effect is superior to comparison, and the lasting period is long.

Embodiment 2

Preventing and treating Festuca Arundinacea brown cecospora spot effect experiment

Select the tall fescue turf that morbidity is serious, random division homalographic community, each process repeats three communities, carry out dispenser in the morning, 10 days are once, altogether dispenser 3 times, in last dispenser 10 days, 15 days, check the state of an illness and calculate preventive effect after 20 days, with clear water as blank, during test, lawn is avoided pruning, applying fertilizer.

The preventive effect of table 2 cecospora spot brown to Festuca Arundinacea

As can be seen from Table 2, the bactericidal composition cecospora spot brown to Festuca Arundinacea that the present invention provides has the longer lasting period, is maintained to the prevention effect of more than 75% after 20 days in dispenser, and compared with comparative example, preventive effect significantly improves.

Drawing through later experiments, the bactericidal composition that the present invention provides all more than 75%, is significantly better than single component to the preventive effect of the Common Diseases such as lawn rust, spot blight, coin pinta, annual bluegrass smut, and potentiation is obvious.

Claims

1. an aqueous emulsion bactericidal composition, it is characterized in that, by difenodiconazole 3.5%, gold alloy hydride 1.5%, tetramycin 2.5%, agriculture breast 600# 4%, agriculture breast 400# 7%, dimethylbenzene 46%, triphenyl phosphite 4%, bentonite 0.3%, sodium benzoate 0.2%, glycerol 2%, deionized water 29%.

The preparation method of a kind of aqueous emulsion bactericidal composition the most as claimed in claim 1, it is characterized in that difenodiconazole, gold alloy hydride, tetramycin, agriculture breast 600#, agriculture breast 400# mix homogeneously are become oil phase, deionized water, dimethylbenzene, triphenyl phosphite, bentonite, sodium benzoate, glycerol are mixed into homogeneous aqueous phase, under high-speed stirred, aqueous phase is added oil phase, prepare described aqueous emulsion.