CN105980810B - 光学断层摄影装置和方法 - Google Patents

光学断层摄影装置和方法 Download PDF

Info

Publication number
CN105980810B
CN105980810B CN201480075374.8A CN201480075374A CN105980810B CN 105980810 B CN105980810 B CN 105980810B CN 201480075374 A CN201480075374 A CN 201480075374A CN 105980810 B CN105980810 B CN 105980810B
Authority
CN
China
Prior art keywords
arm
target
objective
optical
dimensional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480075374.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN105980810A (zh
Inventor
A·杜布瓦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Paris Sud
Institut dOptique Graduate School
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Paris Sud
Institut dOptique Graduate School
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Paris Sud, Institut dOptique Graduate School filed Critical Centre National de la Recherche Scientifique CNRS
Publication of CN105980810A publication Critical patent/CN105980810A/zh
Application granted granted Critical
Publication of CN105980810B publication Critical patent/CN105980810B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • G01B9/0209Low-coherence interferometers
    • G01B9/02091Tomographic interferometers, e.g. based on optical coherence
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0056Optical details of the image generation based on optical coherence, e.g. phase-contrast arrangements, interference arrangements
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0064Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008Details of detection or image processing, including general computer control
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/33Immersion oils, or microscope systems or objectives for use with immersion fluids
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/36Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365Control or image processing arrangements for digital or video microscopes
    • G02B21/367Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/373Surgical systems with images on a monitor during operation using light, e.g. by using optical scanners
    • A61B2090/3735Optical coherence tomography [OCT]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Surgery (AREA)
  • Multimedia (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Quality & Reliability (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Ophthalmology & Optometry (AREA)
CN201480075374.8A 2013-12-20 2014-12-19 光学断层摄影装置和方法 Active CN105980810B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1363234 2013-12-20
FR1363234A FR3015659B1 (fr) 2013-12-20 2013-12-20 Appareil et procede de tomographie optique
PCT/EP2014/078867 WO2015092019A1 (fr) 2013-12-20 2014-12-19 Appareil et procede de tomographie optique

Publications (2)

Publication Number Publication Date
CN105980810A CN105980810A (zh) 2016-09-28
CN105980810B true CN105980810B (zh) 2020-06-19

Family

ID=50473487

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480075374.8A Active CN105980810B (zh) 2013-12-20 2014-12-19 光学断层摄影装置和方法

Country Status (12)

Country Link
US (1) US10317656B2 (enExample)
EP (1) EP3084345B1 (enExample)
JP (1) JP6570531B2 (enExample)
CN (1) CN105980810B (enExample)
AU (1) AU2014368378B2 (enExample)
BR (1) BR112016014297B1 (enExample)
CA (1) CA2934556C (enExample)
DK (1) DK3084345T3 (enExample)
ES (1) ES2800476T3 (enExample)
FR (1) FR3015659B1 (enExample)
IL (1) IL246327B (enExample)
WO (1) WO2015092019A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105942969B (zh) * 2016-06-06 2018-06-19 成都科奥达光电技术有限公司 一种医疗成像系统
JP6762608B2 (ja) * 2016-09-06 2020-09-30 株式会社日立ハイテクサイエンス 走査型白色干渉顕微鏡を用いた三次元形状計測方法
DE102016014802B4 (de) * 2016-12-13 2018-09-27 Universität Stuttgart Anordnung und Verfahren zur robusten Zweistrahl-Interferometrie mit einer Dreifach-Reflexions-Anordnung
CN106815840B (zh) * 2017-01-22 2020-06-05 飞依诺科技(苏州)有限公司 一种肝部扫查图像的处理方法及装置
JP6895306B2 (ja) * 2017-04-26 2021-06-30 キヤノン株式会社 ステージ装置
SG11202002365SA (en) * 2017-09-18 2020-04-29 Apollo Medical Optics Ltd Interference imaging device and its application
CN107726977A (zh) * 2017-09-26 2018-02-23 京东方科技集团股份有限公司 一种位置检测机构及位置检测方法
CN109752354A (zh) * 2017-11-06 2019-05-14 锐准医光股份有限公司 整合米洛光学干涉显微术与荧光显微术的光学切层装置
EP3489619B1 (en) * 2017-11-28 2025-08-13 Koh Young Technology Inc. Apparatus for inspecting substrate and method thereof
AU2019207864B2 (en) 2018-01-12 2023-12-14 Damae Medical Dynamic focusing system for an optical device
EP3628210A1 (en) * 2018-09-28 2020-04-01 Paris Sciences et Lettres - Quartier Latin Methods and systems for in vivo full-field interference microscopy imaging
US11644424B2 (en) * 2019-04-29 2023-05-09 Waverly Industries, Llc Interferometric method and apparatus for non-invasive assessment of oocyte maturity and competency
KR20220080110A (ko) * 2019-10-19 2022-06-14 아폴로 메디컬 옵틱스, 엘티디. 광학 시스템 및 그 간섭 대물렌즈 모듈
KR20220093041A (ko) 2019-11-06 2022-07-05 에이치이에스 아이피 홀딩스, 엘엘씨 깊이를 갖는 오브젝트를 디스플레이하기 위한 시스템 및 방법
FR3103894B1 (fr) 2019-12-03 2024-12-13 Damae Medical Dispositifs et procédés de microscopie à balayage linéaire
WO2021217031A1 (en) * 2020-04-23 2021-10-28 The Regents Of The University Of California Ultrafast light field tomography
EP4127599A1 (en) * 2020-07-01 2023-02-08 Hamamatsu Photonics K.K. Slanted optical coherence tomography imaging for high-speed inspection
FR3112866B1 (fr) 2020-07-22 2022-07-22 Damae Medical Systèmes et procédés d’analyse microscopique d’un échantillon
CN112304246B (zh) * 2020-12-21 2021-03-23 苏州大学 基于空间相干结构调控的光学成像系统及成像方法
FR3119466B1 (fr) 2021-01-29 2023-02-10 Damae Medical Dispositifs pour l’analyse microscopique ex vivo d’échantillons et in vivo de la peau
FR3128627B1 (fr) 2021-10-29 2025-04-18 Damae Medical Systèmes et procédés de caractérisation d’une région d’intérêt d’un tissu biologique
JP7619928B2 (ja) * 2021-11-10 2025-01-22 株式会社コベルコ科研 ウェハ厚さ測定装置および該方法
US20250277965A1 (en) * 2022-04-22 2025-09-04 Sorbonne Universite Module intended to be associated with a microscope, and assembly formed by a microscope and such a module
FR3155065B1 (fr) * 2023-11-08 2025-11-07 Paris Sciences Et Lettres Procédé d'imagerie par tomographie par cohérence optique plein champ, FFOCT, avec réglage d'alignement
CN117804329B (zh) * 2024-03-01 2024-05-31 鹏城实验室 相位干涉显微成像系统

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020021491A1 (en) * 2000-06-23 2002-02-21 Johann Engelhardt Microscope assemblage
CN101243298A (zh) * 2005-08-08 2008-08-13 国立科学研究中心 通过浸没干涉仪显微镜的断层成像
US7884947B2 (en) * 2005-01-20 2011-02-08 Zygo Corporation Interferometry for determining characteristics of an object surface, with spatially coherent illumination
US20110043661A1 (en) * 2008-02-08 2011-02-24 University Of Kent Camera Adapter Based Optical Imaging Apparatus
FR2962531A1 (fr) * 2010-07-08 2012-01-13 Lltech Inc Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ
US20120105859A1 (en) * 2010-10-27 2012-05-03 Samsung Electronics Co., Ltd. Optical Measuring Apparatuses
CN102679866A (zh) * 2007-02-21 2012-09-19 爱克发医疗保健公司 用于光学相干断层扫描的系统和方法
US20120307258A1 (en) * 2010-01-22 2012-12-06 Universitaet Stuttgart Method and arrangement for robust interferometry
CN102822866A (zh) * 2010-03-25 2012-12-12 佳能株式会社 光学断层摄像设备
US20130182096A1 (en) * 2010-09-17 2013-07-18 Lltech Management Optical tissue sectioning using full field optical coherence tomography

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6480285B1 (en) * 1997-01-28 2002-11-12 Zetetic Institute Multiple layer confocal interference microscopy using wavenumber domain reflectometry and background amplitude reduction and compensation
FR2817030B1 (fr) 2000-11-17 2003-03-28 Centre Nat Rech Scient Procede et dispositif d'imagerie microscopique interferentielle d'un objet a haute cadence
US20050225849A1 (en) 2004-04-05 2005-10-13 Fujifilm Electronic Imaging Ltd. Slit confocal microscope and method
WO2006058187A2 (en) * 2004-11-23 2006-06-01 Robert Eric Betzig Optical lattice microscopy
JP5266551B2 (ja) * 2007-07-13 2013-08-21 レーザーテック株式会社 表面形状測定装置、及び表面形状測定方法
DE102008062879B4 (de) * 2008-10-10 2010-10-28 Universität Stuttgart Verfahren und Anordnung zur skalierbaren Interferometrie
US7952723B2 (en) * 2008-12-05 2011-05-31 Kowa Company Ltd. Optical coherence tomography apparatus
US20110261367A1 (en) * 2009-04-27 2011-10-27 Gmitro Arthur F Integrated Confocal and Spectral-Domain Optical Coherence Tomography Microscope
TWI403756B (zh) * 2010-06-18 2013-08-01 Univ Nat Taiwan 三維同調斷層式共焦顯微成像裝置
US9332902B2 (en) * 2012-01-20 2016-05-10 Carl Zeiss Meditec, Inc. Line-field holoscopy
US9360660B2 (en) * 2012-05-24 2016-06-07 Northwestern University Methods and apparatus for laser scanning structured illumination microscopy and tomography
DE102013016752A1 (de) * 2013-09-03 2015-03-05 Universität Stuttgart Verfahren und Anordnung zur robusten One-shot-Interferometrie, insbesondere auch zur optischen Kohärenz-Tomografie nach dem Spatial-domain-Ansatz (SD-OCT)

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020021491A1 (en) * 2000-06-23 2002-02-21 Johann Engelhardt Microscope assemblage
US7884947B2 (en) * 2005-01-20 2011-02-08 Zygo Corporation Interferometry for determining characteristics of an object surface, with spatially coherent illumination
CN101243298A (zh) * 2005-08-08 2008-08-13 国立科学研究中心 通过浸没干涉仪显微镜的断层成像
CN102679866A (zh) * 2007-02-21 2012-09-19 爱克发医疗保健公司 用于光学相干断层扫描的系统和方法
US20110043661A1 (en) * 2008-02-08 2011-02-24 University Of Kent Camera Adapter Based Optical Imaging Apparatus
US20120307258A1 (en) * 2010-01-22 2012-12-06 Universitaet Stuttgart Method and arrangement for robust interferometry
CN102822866A (zh) * 2010-03-25 2012-12-12 佳能株式会社 光学断层摄像设备
FR2962531A1 (fr) * 2010-07-08 2012-01-13 Lltech Inc Methode et dispositif d'imagerie tridimensionnelle par microscopie interferentielle plein champ
US20130182096A1 (en) * 2010-09-17 2013-07-18 Lltech Management Optical tissue sectioning using full field optical coherence tomography
US20120105859A1 (en) * 2010-10-27 2012-05-03 Samsung Electronics Co., Ltd. Optical Measuring Apparatuses

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
High-resolution line-scanning optical coherence microscopy;Yu Chen ET AL;《OPTICS LETTERS》;20070715;第32卷(第14期);第1971-1973页 *
Recent developments in optical coherence tomography for imaging the retina;Mirjam E.J. van Velthoven ET AL;《Progress in Retinal and Eye Research》;20061214;第26卷(第1期);第57-77页 *
Simultaneous measurement of refractive index and thickness by combining low-coherence interferometry and confocal optics;Seokhan Kim ET AL;《OPTICS EXPRESS》;20080414;第16卷(第8期);第5516-5526页 *
Thermal-light full-field optical coherence tomography in the 1.2 μm wavelength region;Arnaud Dubois ET AL;《Optics Communications》;20061015;第266卷(第2期);第738-743页 *

Also Published As

Publication number Publication date
CA2934556A1 (en) 2015-06-25
BR112016014297B1 (pt) 2022-02-01
US20160320598A1 (en) 2016-11-03
CA2934556C (en) 2022-03-01
JP6570531B2 (ja) 2019-09-04
AU2014368378B2 (en) 2019-07-18
US10317656B2 (en) 2019-06-11
JP2017504015A (ja) 2017-02-02
EP3084345A1 (fr) 2016-10-26
FR3015659B1 (fr) 2016-01-29
CN105980810A (zh) 2016-09-28
EP3084345B1 (fr) 2020-03-25
IL246327A0 (en) 2016-07-31
ES2800476T3 (es) 2020-12-30
BR112016014297A2 (enExample) 2017-08-08
WO2015092019A1 (fr) 2015-06-25
DK3084345T3 (da) 2020-06-29
FR3015659A1 (fr) 2015-06-26
AU2014368378A1 (en) 2016-07-07
IL246327B (en) 2020-08-31

Similar Documents

Publication Publication Date Title
CN105980810B (zh) 光学断层摄影装置和方法
JP2017504015A5 (enExample)
US10098538B2 (en) Imaging system
US9255785B2 (en) Method and device for high resolution full field interference microscopy
US7095503B2 (en) Method of full-color optical coherence tomography
CN100488440C (zh) 共路型内窥光学相干层析成像方法及系统
US11852798B2 (en) Systems and methods for performing microscopic analysis of a sample
US7954948B2 (en) Optical tomographic imaging method and apparatus
JP7339447B2 (ja) ライン走査マイクロスコピー用の装置および方法
EP3999897B1 (en) High sensitivity optical devices using pupil splittig means
Cuartas-Vélez et al. Lab-made accessible full-field optical coherence tomography imaging system
Makhlouf et al. A dual modality fluorescence confocal and optical coherence tomography microendoscope
Liu et al. Full-field optical coherence tomography using a spatial filter
Langevin et al. New setups for optical coherence tomography

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant