CN105968416B - A kind of antibacterial agent for antibiotic plastic - Google Patents
A kind of antibacterial agent for antibiotic plastic Download PDFInfo
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- CN105968416B CN105968416B CN201610354059.XA CN201610354059A CN105968416B CN 105968416 B CN105968416 B CN 105968416B CN 201610354059 A CN201610354059 A CN 201610354059A CN 105968416 B CN105968416 B CN 105968416B
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- 229920003023 plastic Polymers 0.000 title claims abstract description 32
- 239000004033 plastic Substances 0.000 title claims abstract description 32
- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 31
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 22
- 239000000843 powder Substances 0.000 claims abstract description 67
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 38
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 23
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 17
- 150000001413 amino acids Chemical class 0.000 claims abstract description 16
- 239000007822 coupling agent Substances 0.000 claims abstract description 16
- 239000003085 diluting agent Substances 0.000 claims abstract description 16
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 15
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims abstract description 14
- 238000002360 preparation method Methods 0.000 claims abstract description 13
- 235000019441 ethanol Nutrition 0.000 claims abstract description 12
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims abstract description 11
- 229910021536 Zeolite Inorganic materials 0.000 claims abstract description 11
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000012054 meals Nutrition 0.000 claims abstract description 11
- SDLBJIZEEMKQKY-UHFFFAOYSA-M silver chlorate Chemical compound [Ag+].[O-]Cl(=O)=O SDLBJIZEEMKQKY-UHFFFAOYSA-M 0.000 claims abstract description 11
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical group [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims abstract description 11
- 239000001488 sodium phosphate Substances 0.000 claims abstract description 11
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 claims abstract description 11
- 235000019345 sodium thiosulphate Nutrition 0.000 claims abstract description 11
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims abstract description 11
- 229910000406 trisodium phosphate Inorganic materials 0.000 claims abstract description 11
- 235000019801 trisodium phosphate Nutrition 0.000 claims abstract description 11
- 239000010457 zeolite Substances 0.000 claims abstract description 11
- 239000010445 mica Substances 0.000 claims abstract description 10
- 229910052618 mica group Inorganic materials 0.000 claims abstract description 10
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000010265 sodium sulphite Nutrition 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000007787 solid Substances 0.000 claims description 35
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 32
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 27
- 239000000243 solution Substances 0.000 claims description 22
- 239000011259 mixed solution Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 18
- 229960000583 acetic acid Drugs 0.000 claims description 15
- 238000001035 drying Methods 0.000 claims description 10
- -1 silane compound Chemical class 0.000 claims description 10
- 239000012265 solid product Substances 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 9
- 229910000077 silane Inorganic materials 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000003801 milling Methods 0.000 claims description 5
- 238000002390 rotary evaporation Methods 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 238000002604 ultrasonography Methods 0.000 claims description 5
- 238000005406 washing Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000004475 Arginine Substances 0.000 claims description 4
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 4
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims description 4
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 4
- 239000006185 dispersion Substances 0.000 claims description 4
- 239000012153 distilled water Substances 0.000 claims description 4
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims description 4
- FZHAPNGMFPVSLP-UHFFFAOYSA-N silanamine Chemical compound [SiH3]N FZHAPNGMFPVSLP-UHFFFAOYSA-N 0.000 claims description 4
- UKRDPEFKFJNXQM-UHFFFAOYSA-N vinylsilane Chemical class [SiH3]C=C UKRDPEFKFJNXQM-UHFFFAOYSA-N 0.000 claims description 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 3
- 239000004472 Lysine Substances 0.000 claims description 3
- 230000004913 activation Effects 0.000 claims description 3
- 239000006210 lotion Substances 0.000 claims description 3
- UNIYDALVXFPINL-UHFFFAOYSA-N 3-(2-methylprop-2-enoyloxy)propylsilicon Chemical compound CC(=C)C(=O)OCCC[Si] UNIYDALVXFPINL-UHFFFAOYSA-N 0.000 claims description 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims description 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 2
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims description 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical group [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 1
- 238000011001 backwashing Methods 0.000 claims 1
- 230000002882 anti-plaque Effects 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 6
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 5
- 239000000047 product Substances 0.000 description 4
- 229910052938 sodium sulfate Inorganic materials 0.000 description 4
- 235000011152 sodium sulphate Nutrition 0.000 description 4
- 238000010792 warming Methods 0.000 description 4
- 239000003513 alkali Substances 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 239000004599 antimicrobial Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000007935 neutral effect Effects 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 238000002845 discoloration Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 150000001455 metallic ions Chemical class 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- MOVRCMBPGBESLI-UHFFFAOYSA-N prop-2-enoyloxysilicon Chemical compound [Si]OC(=O)C=C MOVRCMBPGBESLI-UHFFFAOYSA-N 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K13/00—Use of mixtures of ingredients not covered by one single of the preceding main groups, each of these compounds being essential
- C08K13/06—Pretreated ingredients and ingredients covered by the main groups C08K3/00 - C08K7/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/16—Halogen-containing compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/24—Acids; Salts thereof
- C08K3/26—Carbonates; Bicarbonates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/32—Phosphorus-containing compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/34—Silicon-containing compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/17—Amines; Quaternary ammonium compounds
- C08K5/175—Amines; Quaternary ammonium compounds containing COOH-groups; Esters or salts thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K9/00—Use of pretreated ingredients
- C08K9/02—Ingredients treated with inorganic substances
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K9/00—Use of pretreated ingredients
- C08K9/04—Ingredients treated with organic substances
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/24—Acids; Salts thereof
- C08K3/26—Carbonates; Bicarbonates
- C08K2003/265—Calcium, strontium or barium carbonate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/32—Phosphorus-containing compounds
- C08K2003/321—Phosphates
- C08K2003/324—Alkali metal phosphate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/014—Additives containing two or more different additives of the same subgroup in C08K
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- Chemical Kinetics & Catalysis (AREA)
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- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
Abstract
The invention belongs to antibacterial agent fields, specifically disclose a kind of antibacterial agent and preparation method thereof for antibiotic plastic.It is characterized in that, it include mainly following raw material, by parts by weight meter: 20~35 parts of white mica powder, 5~15 parts of zeolite powder, 5~15 parts of conch meal, 40~60 parts of 30% hydrogen peroxide, 40~80 parts of trisodium phosphate solution, 0.4~6 part of basic amino acid, 20~35 parts of silver chlorate, 40~55 parts of sodium thiosulfate, 20~30 parts of sodium sulfite, 5~10 parts of acetic acid, Na4P2O7·10H25~15 parts of O, 30~45 parts of thioglycol, 20~35 parts of ethyl alcohol, 10~25 parts of sodium bicarbonate, 15~40 parts of diluent, 5~20 parts of coupling agent.Antibacterial antiplaque agent effect provided by the invention is obvious, good with the compatibility of plastics.
Description
Technical field
The invention belongs to antibacterial agent fields, concretely relate to a kind of for the antibacterial agent of antibiotic plastic and its preparation side
Method.
Background technique
With the progress of human society, plastic products occupy increasingly consequence in daily life.At the same time,
Various environmental pollutions are also got worse, and plastic products are easy the pollution by bacterium in the long-term use, have been directly resulted in
The propagation and sprawling of evil bacterium, endanger people's health.Antibacterial agent can effectively inhibit the taste of bacterium as a kind of additive
It is raw.Plastic antimicrobial agent is generally divided into inorganic antiseptic, organic antibacterial agent, natural antibacterial agent and complex antimicrobials.But addition at present
Most of antibacterial antiplaque agent effects into plastics are unobvious, bad with the compatibility of plastics.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of antibacterial agent and preparation method thereof for antibiotic plastic, with
Improve the problem that existing plastic antimicrobial agent antibacterial effect is unobvious, bad with the compatibility of plastics.
In order to achieve the above objectives, the technical solution used in the present invention are as follows:
A kind of antibacterial agent for antibiotic plastic includes mainly following raw material, by parts by weight meter: white mica powder 20~35
Part, 5~15 parts of zeolite powder, 5~15 parts of conch meal, 40~60 parts of 30% hydrogen peroxide, 40~80 parts of trisodium phosphate solution, alkaline ammonia
0.4~6 part of base acid, 20~35 parts of silver chlorate, 40~55 parts of sodium thiosulfate, 20~30 parts of sodium sulfite, 5~10 parts of acetic acid,
Na4P2O7·10H25~15 parts of O, 30~45 parts of thioglycol, 20~35 parts of ethyl alcohol, 10~25 parts of sodium bicarbonate, diluent 15
~40 parts, 5~20 parts of coupling agent.
Preferably, in the preferred embodiment, the basic amino acid is lysine, arginine, histidine, color
It is one or more kinds of in propylhomoserin.
Preferably, in the preferred embodiment, the diluent is ethylene glycol, propylene glycol, wherein ethylene glycol, third
The ratio of glycol is 1:1~1.2.
Preferably, in the preferred embodiment, the coupling agent is silane compound.
Preferably, in the preferred embodiment, the silane compound is amino silane, vinyl silanes or first
One or both of base acryloxy silane.
The present invention also provides a kind of preparation methods of antibacterial agent for antibiotic plastic, comprising the following steps:
(1) white mica powder, the zeolite powder, the conch meal are uniformly mixed to obtain hybrid solid powder, it will be described
Hybrid solid powder and 30% hydrogen peroxide solution are stirred 10~15min, then stand 50~70min, place it in
Dry 6~8h in 100~120 DEG C of baking ovens；
(2) by the hybrid solid powder and the trisodium phosphate solution, basic amino acid stirring 15 after drying
~35min then stands 20~40min, and 5~7min is centrifugated under the speed of 3000~4000r/min, takes lower sediment
3~5h is toasted in 350~400 DEG C of baking ovens, then stands and is cooled to 20~30 DEG C, is prepared into purifying hybrid solid powder, it will
The pure solid powder collected is placed in high pressure milling device, is milled and is sieved at 10~15MPa, it is prepared into 120~
140 mesh ultrafine solids powder；
(3) silver chlorate is dissolved in the mixed solution of the sodium sulphate and the sodium thiosulfate, while uses institute
Vinegar acid for adjusting pH is stated 4~5,2~4h is stirred at 20~40 DEG C；
(4) the ultrafine solids powder is added in the mixed solution of step (3) preparation by 1:10~15 in mass ratio,
Being warming up to 55~60 DEG C, the acetic acid is added to adjust pH value is 6~8, stirs 1~2h, then be centrifugated to obtain solid product, distills
Water wash repeatedly the solid product into washing lotion without Ag+ after, dried at 100~110 DEG C, obtain immobilized silver-colored antibacterial pulvis；
(5) the immobilized silver-colored antibacterial pulvis is added to the Na4P2O7·10H2In O, stirred at 25~65 DEG C molten
It solves 2~4 hours, is stirred 10~15min under 600~800r/min revolving speed, continuously adds sodium bicarbonate, the ethyl alcohol, institute
Thioglycol is stated, the ultrasound for applying 750~800W at 20~30 DEG C carries out 10~15min of decentralized processing to solution, and 20
4~6h is mixed at~30 DEG C, mixing speed is 100~200r/min；
(6) diluent and coupling agent 3:1~1.5 in mass ratio are first mixed to get mixed solution, then will step
Suddenly solution is mixed with above-mentioned mixed solution 1:0.2~0.5 in mass ratio after the dispersion that (5) obtain, then in a high speed mixer
Stirring 20~30 minutes after the completion of to be mixed, stands 10~12h, and remove solvent to its rotary evaporation, then be placed in 75~80 DEG C
The particle is milled and is sieved again, is prepared into 140~160 by dry 6~8h in baking oven, the particle after collecting drying
Mesh powder, then the powder is subjected to 2~4h of activation processing at 180~240 DEG C, then stop heating up and be cooled to 20~
30 DEG C, obtain the antibacterial agent for antibiotic plastic.
Beneficial effects of the present invention: the present invention is using the high bio-molecules basic amino acid of biological safety as anti-
Antibacterial substance silver ion is evenly spread to nanoparticle surface, improves antibacterial agent by bacterium active metallic ion dispersing agent
Anti-microbial property.Antibacterial agent provided by the invention is good with Compatibility in Plastics, can effectively inhibit the growth of bacterium, to Escherichia coli,
For the inhibition killing rate of the strains such as staphylococcus aureus up to 99% or more, antibacterial effect is obvious.
Specific embodiment
Technical solution of the present invention is further described combined with specific embodiments below.
Embodiment 1:
A kind of antibacterial agent for antibiotic plastic includes mainly following raw material, by parts by weight meter: 20 parts of white mica powder,
5 parts of zeolite powder, 5 parts of conch meal, 40 parts of 30% hydrogen peroxide, 40 parts of trisodium phosphate solution, 0.4 part of basic amino acid, silver chlorate 20
Part, 40 parts of sodium thiosulfate, 20 parts of sodium sulfite, 5 parts of acetic acid, Na4P2O7·10H25 parts of O, 30 parts of thioglycol, ethyl alcohol 20
Part, 10 parts of sodium bicarbonate, 15 parts of diluent, 5 parts of coupling agent.
The present embodiment neutral and alkali amino acid is lysine and arginic mixture.
In the present embodiment diluent be ethylene glycol, propylene glycol, wherein ethylene glycol, propylene glycol ratio be 1:1.
Coupling agent is silane compound in the present embodiment.
Silane compound is amino silane in the present embodiment.
The present embodiment additionally provides a kind of preparation method of antibacterial agent for antibiotic plastic, comprising the following steps:
(1) white mica powder, zeolite powder, conch meal are uniformly mixed to obtain hybrid solid powder, by hybrid solid powder and 30%
Hydrogen peroxide solution is stirred 10min, then stands 50min, places it in dry 6h in 100 DEG C of baking ovens；
(2) it by the hybrid solid powder and trisodium phosphate solution, basic amino acid stirring 15min after drying, then stands
20min is centrifugated 5min under the speed of 3000r/min, takes lower layer to be deposited in 350 DEG C of baking ovens and toasts 3h, then stands
20 DEG C are cooled to, purifying hybrid solid powder is prepared into, the pure solid powder of collection is placed in high pressure milling device,
It mills and is sieved under 10MPa, be prepared into 120 mesh ultrafine solids powder；
(3) silver chlorate is dissolved in the mixed solution of sodium sulphate and sodium thiosulfate, while with vinegar acid for adjusting pH 4,
2h is stirred at 20 DEG C；
(4) ultrafine solids powder is added in the mixed solution of step (3) preparation by 1:10 in mass ratio, is warming up to 55
DEG C, acetic acid is added to adjust pH value is 6, stirs 1h, then is centrifugated to obtain solid product, distilled water washs solid product to washing repeatedly
In liquid without Ag+ after, dried at 100 DEG C, obtain immobilized silver-colored antibacterial pulvis；
(5) immobilized silver-colored antibacterial pulvis is added to Na4P2O7·10H2In O, stirring and dissolving 2 hours, 600r/ at 25 DEG C
It is stirred 10min under min revolving speed, continuously adds sodium bicarbonate, ethyl alcohol, thioglycol, applies the ultrasound of 750W at 20 DEG C
Decentralized processing 10min is carried out to solution, and 4h is mixed at 20 DEG C, mixing speed 100r/min；
(6) diluent and coupling agent 3:1 in mass ratio are first mixed to get mixed solution, then point that step (5) is obtained
Solution is mixed with above-mentioned mixed solution 1:0.2 in mass ratio after dissipating, and is then stirred 20 minutes in a high speed mixer, to be mixed complete
Cheng Hou stands 10h, and removes solvent to its rotary evaporation, then is placed in 75 DEG C of baking ovens dry 6h, the particle after collecting drying,
Particle is milled and is sieved again, is prepared into 140 mesh powders, then powder is subjected to activation processing 2h at 180 DEG C, with
Stop heating up and being cooled to 20 DEG C afterwards, obtains the antibacterial agent for antibiotic plastic.
Embodiment 2:
A kind of antibacterial agent for antibiotic plastic includes mainly following raw material, by parts by weight meter: 35 parts of white mica powder,
15 parts of zeolite powder, 15 parts of conch meal, 60 parts of 30% hydrogen peroxide, 80 parts of trisodium phosphate solution, 6 parts of basic amino acid, silver chlorate 35
Part, 55 parts of sodium thiosulfate, 30 parts of sodium sulfite, 10 parts of acetic acid, Na4P2O7·10H215 parts of O, 45 parts of thioglycol, ethyl alcohol
35 parts, 25 parts of sodium bicarbonate, 40 parts of diluent, 20 parts of coupling agent.
The present embodiment neutral and alkali amino acid is the mixture of arginine and histidine.
In the present embodiment diluent be ethylene glycol, propylene glycol, wherein ethylene glycol, propylene glycol ratio be 1:1.2.
Coupling agent is silane compound in the present embodiment.
Silane compound is vinyl silanes in the present embodiment.
The present embodiment additionally provides a kind of preparation method of antibacterial agent for antibiotic plastic, comprising the following steps:
(1) white mica powder, zeolite powder, conch meal are uniformly mixed to obtain hybrid solid powder, by hybrid solid powder and 30%
Hydrogen peroxide solution is stirred 15min, then stands 70min, places it in dry 8h in 120 DEG C of baking ovens；
(2) it by the hybrid solid powder and trisodium phosphate solution, basic amino acid stirring 35min after drying, then stands
40min is centrifugated 7min under the speed of 4000r/min, takes lower layer to be deposited in 400 DEG C of baking ovens and toasts 5h, then stands
30 DEG C are cooled to, purifying hybrid solid powder is prepared into, the pure solid powder of collection is placed in high pressure milling device,
It mills and is sieved under 15MPa, be prepared into 140 mesh ultrafine solids powder；
(3) silver chlorate is dissolved in the mixed solution of sodium sulphate and sodium thiosulfate, while with vinegar acid for adjusting pH 5,
4h is stirred at 40 DEG C；
(4) ultrafine solids powder is added in the mixed solution of step (3) preparation by 1:15 in mass ratio, is warming up to 60
DEG C, acetic acid is added to adjust pH value is 8, stirs 2h, then is centrifugated to obtain solid product, distilled water washs solid product to washing repeatedly
In liquid without Ag+ after, dried at 110 DEG C, obtain immobilized silver-colored antibacterial pulvis；
(5) immobilized silver-colored antibacterial pulvis is added to Na4P2O7·10H2In O, stirring and dissolving 4 hours at 65 DEG C,
It is stirred 15min under 800r/min revolving speed, continuously adds sodium bicarbonate, ethyl alcohol, thioglycol, applies 800W's at 30 DEG C
Ultrasound carries out decentralized processing 15min to solution, and 6h is mixed at 30 DEG C, mixing speed 200r/min；
(6) diluent and coupling agent 3:1.5 in mass ratio are first mixed to get mixed solution, then step (5) is obtained
Solution is mixed with above-mentioned mixed solution 1:0.5 in mass ratio after dispersion, is then stirred 30 minutes in a high speed mixer, wait stir
After the completion of mixing, 12h is stood, and solvent is removed to its rotary evaporation, then is placed in 80 DEG C of baking ovens dry 8h, after collecting drying
Grain, particle is milled and is sieved again, be prepared into 160 mesh powders, then powder is activated at 240 DEG C
4h then stops heating up and being cooled to 30 DEG C, obtains the antibacterial agent for antibiotic plastic.
Embodiment 3:
A kind of antibacterial agent for antibiotic plastic includes mainly following raw material, by parts by weight meter: 27 parts of white mica powder,
10 parts of zeolite powder, 10 parts of conch meal, 50 parts of 30% hydrogen peroxide, 60 parts of trisodium phosphate solution, 3.2 parts of basic amino acid, silver chlorate 27
Part, 48 parts of sodium thiosulfate, 25 parts of sodium sulfite, 7 parts of acetic acid, Na4P2O7·10H210 parts of O, 37 parts of thioglycol, ethyl alcohol 27
Part, 17 parts of sodium bicarbonate, 27 parts of diluent, 12 parts of coupling agent.
The present embodiment neutral and alkali amino acid is the mixture of arginine, histidine and tryptophan.
In the present embodiment diluent be ethylene glycol, propylene glycol, wherein ethylene glycol, propylene glycol ratio be 1:1~1.1.
Coupling agent is silane compound in the present embodiment.
Silane compound is the mixing of amino silane, vinyl silanes or methacryloxypropyl silane in the present embodiment
Object.
The present embodiment additionally provides a kind of preparation method of antibacterial agent for antibiotic plastic, comprising the following steps:
(1) white mica powder, zeolite powder, conch meal are uniformly mixed to obtain hybrid solid powder, by hybrid solid powder and 30%
Hydrogen peroxide solution is stirred 12min, then stands 60min, places it in dry 7h in 110 DEG C of baking ovens；
(2) it by the hybrid solid powder and trisodium phosphate solution, basic amino acid stirring 25min after drying, then stands
30min is centrifugated 6min under the speed of 3500r/min, takes lower layer to be deposited in 375 DEG C of baking ovens and toasts 4h, then stands
25 DEG C are cooled to, purifying hybrid solid powder is prepared into, the pure solid powder of collection is placed in high pressure milling device,
It mills and is sieved under 12MPa, be prepared into 130 mesh ultrafine solids powder；
(3) silver chlorate is dissolved in the mixed solution of sodium sulphate and sodium thiosulfate, while being existed with vinegar acid for adjusting pH
4.5,3h is stirred at 30 DEG C；
(4) ultrafine solids powder is added in the mixed solution of step (3) preparation by 1:12 in mass ratio, is warming up to 57
DEG C, acetic acid is added to adjust pH value is 7, stir 1.5h, then be centrifugated to obtain solid product, distilled water washs solid product extremely repeatedly
In washing lotion without Ag+ after, dried at 105 DEG C, obtain immobilized silver-colored antibacterial pulvis；
(5) immobilized silver-colored antibacterial pulvis is added to Na4P2O7·10H2In O, stirring and dissolving 3 hours, 700r/ at 45 DEG C
It is stirred 12min under min revolving speed, continuously adds sodium bicarbonate, ethyl alcohol, thioglycol, applies the ultrasound of 770W at 25 DEG C
Decentralized processing 12min is carried out to solution, and 5h is mixed at 25 DEG C, mixing speed 150r/min；
(6) diluent and coupling agent 3:1.2 in mass ratio are first mixed to get mixed solution, then step (5) is obtained
Solution is mixed with above-mentioned mixed solution 1:0.3 in mass ratio after dispersion, is then stirred 25 minutes in a high speed mixer, to be mixed
After the completion, 11h is stood, and solvent is removed to its rotary evaporation, then is placed in 77 DEG C of baking ovens dry 7h, after collecting drying
Grain, particle is milled and is sieved again, be prepared into 150 mesh powders, then powder is activated at 210 DEG C
3h then stops heating up and being cooled to 25 DEG C, obtains the antibacterial agent for antibiotic plastic.
Antibacterial agent quality made from embodiment 1-3 is detected, by carrying out 96 hours ultraviolet lights to product,
Discoloration-resistant, the anti-microbial property of antibacterial agent are detected.By comparison, it was found that product made from embodiment 3 and plastic compatible
Property it is more preferable, discoloration-resistant is stronger, inhibit bacterium ability it is stronger, anti-microbial property is more preferable.
Claims (4)
1. a kind of antibacterial agent for antibiotic plastic, which is characterized in that include mainly following raw material, by parts by weight meter: white clouds
20~35 parts of female powder, 5~15 parts of zeolite powder, 5~15 parts of conch meal, 40~60 parts of 30% hydrogen peroxide, trisodium phosphate solution 40~80
Part, 0.4~6 part of basic amino acid, 20~35 parts of silver chlorate, 40~55 parts of sodium thiosulfate, 20~30 parts of sodium sulfite, acetic acid
5~10 parts, Na4P2O7·10H25~15 parts of O, 30~45 parts of thioglycol, 20~35 parts of ethyl alcohol, 10~25 parts of sodium bicarbonate,
15~40 parts of diluent, 5~20 parts of coupling agent；
The basic amino acid is lysine, arginine, histidine, one or more kinds of in tryptophan；
The diluent be ethylene glycol, propylene glycol, wherein ethylene glycol, propylene glycol ratio be 1:1~1.2.
2. a kind of antibacterial agent for antibiotic plastic according to claim 1, it is characterised in that: the coupling agent is silicon
Hydride compounds.
3. a kind of antibacterial agent for antibiotic plastic according to claim 2, it is characterised in that: the silane compound
For one or both of amino silane, vinyl silanes or methacryloxypropyl silane.
4. a kind of preparation method of the antibacterial agent as described in any one of claims 1-3 for antibiotic plastic, which is characterized in that
The following steps are included:
(1) white mica powder, the zeolite powder, the conch meal are uniformly mixed to obtain hybrid solid powder, by the mixing
Solid powder and 30% hydrogen peroxide solution are stirred 10~15min, then stand 50~70min, place it in 100~
Dry 6~8h in 120 DEG C of baking ovens；
(2) by after drying the hybrid solid powder and the trisodium phosphate solution, the basic amino acid stirring 15~
35min then stands 20~40min, and 5~7min is centrifugated under the speed of 3000~4000r/min, lower layer is taken to be deposited in
3~5h is toasted in 350~400 DEG C of baking ovens, then stands and is cooled to 20~30 DEG C, is prepared into purifying hybrid solid powder, will be received
The pure solid powder of collection is placed in high pressure milling device, is milled and is sieved at 10~15MPa, is prepared into 120~140
Mesh ultrafine solids powder；
(3) silver chlorate is dissolved in the mixed solution of the sodium sulfite and the sodium thiosulfate, while described in use
Vinegar acid for adjusting pH stirs 2~4h 4~5 at 20~40 DEG C；
(4) the ultrafine solids powder is added in the mixed solution of step (3) preparation by 1:10~15 in mass ratio, heating
Adjusting pH value to 55~60 DEG C, the addition acetic acid is 6~8, stirs 1~2h, then be centrifugated to obtain solid product, distilled water is anti-
After backwashing wash the solid product into washing lotion without Ag+ after, in 100~110 DEG C of baking ovens, obtain immobilized silver-colored antibacterial pulvis；
(5) the immobilized silver-colored antibacterial pulvis is added to the Na4P2O7·10H2In O, the stirring and dissolving 2~4 at 25~65 DEG C
Hour, it is stirred 10~15min under 600~800r/min revolving speed, continuously adds sodium bicarbonate, the ethyl alcohol, the sulfenyl
Ethyl alcohol, the ultrasound for applying 750~800W at 20~30 DEG C carry out 10~15min of decentralized processing to solution, and at 20~30 DEG C
4~6h of lower mixing, mixing speed are 100~200r/min；
(6) diluent and coupling agent 3:1~1.5 in mass ratio are first mixed to get mixed solution, then by step (5)
Solution is mixed with above-mentioned mixed solution 1:0.2~0.5 in mass ratio after obtained dispersion, then stirs 20 in a high speed mixer
~30 minutes, after the completion of to be mixed, 10~12h is stood, and solvent is removed to its rotary evaporation, then be placed in 75~80 DEG C of baking ovens
Dry 6~8h, the particle after collecting drying, the particle is milled and is sieved again, be prepared into the powder of 140~160 mesh
End, then the powder is subjected to 2~4h of activation processing at 180~240 DEG C, then stop heating up and being cooled to 20~30 DEG C,
Obtain the antibacterial agent for antibiotic plastic.
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| CN1686789A (en) * | 2005-04-19 | 2005-10-26 | 浙江大学 | Load type nano selenium and preparation method |
| CN102660112A (en) * | 2012-04-18 | 2012-09-12 | 东莞市纳为电子科技有限公司 | Secondary processing method for carbon nanotubes |
| CN104585235A (en) * | 2014-12-31 | 2015-05-06 | 芜湖恒杰膨润土科技有限公司 | Silver-loaded bentonite and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1686789A (en) * | 2005-04-19 | 2005-10-26 | 浙江大学 | Load type nano selenium and preparation method |
| CN102660112A (en) * | 2012-04-18 | 2012-09-12 | 东莞市纳为电子科技有限公司 | Secondary processing method for carbon nanotubes |
| CN104585235A (en) * | 2014-12-31 | 2015-05-06 | 芜湖恒杰膨润土科技有限公司 | Silver-loaded bentonite and preparation method thereof |
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