CN105964156A - Preparation method of hollow fiber blood purification membrane and special device thereof - Google Patents
Preparation method of hollow fiber blood purification membrane and special device thereof Download PDFInfo
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- CN105964156A CN105964156A CN201610536101.XA CN201610536101A CN105964156A CN 105964156 A CN105964156 A CN 105964156A CN 201610536101 A CN201610536101 A CN 201610536101A CN 105964156 A CN105964156 A CN 105964156A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
- B01D71/68—Polysulfones; Polyethersulfones
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/30—Polyalkenyl halides
- B01D71/32—Polyalkenyl halides containing fluorine atoms
- B01D71/34—Polyvinylidene fluoride
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/48—Polyesters
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/56—Polyamides, e.g. polyester-amides
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2323/00—Details relating to membrane preparation
- B01D2323/42—Details of membrane preparation apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/36—Hydrophilic membranes
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Abstract
The invention discloses a preparation method of a hollow fiber blood purification membrane and a special device thereof and relates to the technical field of preparation of blood purification membranes. The preparation method comprises the following steps: preparing a solution, spraying filaments, carrying out gelatinization, washing with water, drying and winding filaments, wherein the membrane filaments sprayed by a filament spraying head are subjected to gelatinization and washed with water; then the membrane filaments are subjected to oxygen plasma treatment for 10-20 seconds; then the membrane filaments are dried and wound. The special device comprises a spinning solution preparing tank, a core solution tank, a spinneret plate, a gelatinization device, a washing device, a drying device and a winding device, wherein an oxygen plasma treatment device is arranged between the washing device and the drying device. Hydrophilicity and blood coagulation resistance of the hollow fiber blood purification membrane prepared by the method are significantly improved; the special device is used for implementing the method, so that the preparation process of the hollow fiber blood purification membrane is integrative and automatic; the production process is greatly simplified; the production difficulty is reduced; the technical foundation is established for large-scale industrial production.
Description
Technical field
The present invention relates to blood purification membrane preparation method and equipment technical field, say it is that a kind of hollow fibre blood is clean in detail
Change preparation method and the special equipment of film.
Background technology
It is known that the dialyser used by blood purification is also referred to as " artificial kidney ", its core is to fill up to ten thousand therein
Hollow-fiber film, and on every hollow-fiber film, all it is dispersed with numerous small holes.During blood purification, blood is saturating in hollow fibre
Analysis liquid flows counterflow through outside hollow fibre, and in blood/dialysis solution, solute and the moisture of some little molecules i.e. pass through on hollow fibre
Aperture swap, final result is that the uremic toxins in blood and some electrolyte, unnecessary moisture enter dialysis solution
In be eliminated, in dialysis solution, some benefit materials such as bicarbonate radical and electrolyte enter in blood, thus reach to remove toxin, water
Divide, maintain acid-base balance and homeostatic purpose.
It is known that mostly be hydrophobic for producing the material of main part (such as polysulfones, polyether sulfone) of membrane for purifying blood, existing
Technology exists and several improves the hydrophilic method of film.As: United States Patent (USP) NO.4618533 discloses by being directly coated with film
The method making PES film hydrophiling；There is coated technique complexity, waste time and energy in this type of method, production efficiency is low, manufacturing cost
Height, is not easy to the shortcomings such as industrialized production.
Document " Surface modification of POLY (ether sulfone) Ultrafiltration
Membranes by Low-Temperature Plasma-Induced Graft Polymerization " (Journal of
Applied Polyer science, Vol.72,1699-1711(1999)) describe and make hydrophilic PES film through low temperature helium etc.
Gas ions processes, and is grafted on the surface of film by hydrophilic monomer, and it equally exists complex process, production efficiency is low, manufacture
Cost is high, the shortcoming being unfavorable for industrialized production.
Summary of the invention
Present invention aim to address above-mentioned the deficiencies in the prior art, it is provided that a kind of technique is simple, production efficiency is high, manufacture
With low cost, the beneficially preparation method of the hollow fibre membrane for purifying blood of industrialized production and special equipment.
The present invention solves the deficiencies in the prior art and be the technical scheme is that
The preparation method of a kind of hollow fibre membrane for purifying blood, including dosing, spray webbing, gelation, washes, dries, receives silk, and it is special
Levy and be: described dosing includes preparation and the preparation of core liquid of spinning liquid, and described spinning liquid is by high molecular polymer, You Jirong
Agent, additive, biocompatible materials mix under 80-120 degree Celsius, stir formation homogeneous phase solution, are then passed through evacuation
Deaeration processes and prepares；Described core liquid is the solution of concentration 0wt%-50wt% that core liquid solvent is uniformly mixed to prepare with water；Spray webbing
The film silk of head ejection, after gelation, washing, carries out oxygen plasma and processes 10-20s, then carries out drying, receiving silk operation.
Heretofore described high molecular polymer is in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide
The blend of at least one and SPSF；Described organic solvent is in dimethyl acetylamide, N-methyl pyrrolidone
At least one；Described additive has pore effect, specially polyvinylpyrrolidone, Polyethylene Glycol, hydroxy kind cellulose
In at least one；Described biocompatible materials includes the mixed of one or both in polyvinyl alcohol and polyethylene glycol oxide
Close.Described core liquid solvent is at least one in DMAc, DMF, DMSO, NMP.
Heretofore described spinning liquid is by high molecular polymer, organic solvent, additive, the polymerization of bio-compatible sexual function
Thing is in mass ratio: high molecular polymer: organic solvent: additive: biocompatible materials=11:25-30:1.5-2:2-3 system
?.
In the heretofore described polysulfones in high molecular polymer, polyether sulfone, Kynoar, polylactic acid, polyamide
At least one and SPSF be in mass ratio: at least in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide
Kind: SPSF=8-12:1, preferably 9.5-10.5:1.Hollow fibre membrane for purifying blood under this component proportion, through peroxide etc. from
Its blood ultrafiltration rate, hydrophilic and clotting time after daughter processes are obtained for the biggest raising.
A kind of special equipment for realizing above-mentioned preparation method, it is characterised in that include spinning liquid material-compound tank, core flow container,
Spinneret, device of gel, water washing device, drying unit, coiler device, be provided with oxygen etc. between described water washing device and drying unit
Gas ions processing means.
The structure of heretofore described spinning liquid material-compound tank is: be provided with tank body, tank body be provided with charging aperture, discharging opening and
Heater, is provided with agitator in tank body；The structure of described core flow container is: being provided with tank body, tank body is provided with charging aperture and discharging
Mouthful, it is provided with agitator in tank body；Described spinneret is inserting pipe-type porous spinneret；The structure of described device of gel is:
Being provided with gel box, gel box is provided with film silk entrance, the outlet of film silk, the temperature inside the box control device and case humidity control device；
The structure of described water washing device is: be provided with water washing chamber, and water washing chamber top is provided with film silk entrance and the outlet of film silk, in water washing chamber on
Portion and bottom warp beam respectively is held and is provided with break-in guide reel, is provided with water circulating pump, and water circulating pump water inlet connects with bottom water washing chamber,
Water circulating pump outlet connects with the water washing chamber of film silk outlet side；The structure of described drying unit is: be provided with drying baker, dries
It is respectively equipped with film silk entrance and the outlet of film silk on dry case, in drying baker, between film silk entrance and the outlet of film silk, is provided with film silk carrying roller, film
It is provided with heater below silk carrying roller, below heater, is provided with air-blast device；The structure of described coiler device is: is provided with and props up
Frame, support is provided with wire wrapping wheel, and wire wrapping wheel side is provided with device of rotation driving；The structure of described oxygen plasma treatment device
It is: be provided with treatment box to be respectively equipped with film silk entrance and the outlet of film silk on treatment box, in treatment box, be provided with oxygen intake and plasma
Generating means.
In agitator in the heretofore described heater in spinning liquid material-compound tank, agitator, core flow container, gel box
The temperature inside the box control device and case humidity control device, the water circulating pump of water washing device, plasma generator, drying baker
Interior heater is connected with master controller with the control panel such as air-blast device, device of rotation driving.
Hollow fibre membrane for purifying blood hydrophilic and anticoagulant property that the method for the employing present invention is prepared have obtained significantly
Raising；Use assembly of the invention to realize said method, make hollow fibre membrane for purifying blood preparation flow integrated, automatically
Change, significantly simplify production procedure, reduce production difficulty, established technical foundation for large-scale industrial production.
Accompanying drawing explanation
Fig. 1 is the process chart of the present invention；
Fig. 2 is the production device structure schematic diagram of the present invention；
Fig. 3 is the photo of the hollow fibre membrane for purifying blood inner surface platelet adhesion after the use captured by ultramicroscope
Figure；Photo figure after perineurium prepared by example 1 uses during wherein Fig.1 is detailed description of the invention, Fig.2 is specific embodiment party
Photo figure after perineurium prepared by example 2 uses in formula, Fig.3 is that in detailed description of the invention, perineurium prepared by example 3 makes
Photo figure after with.
Wherein, 1-Agitation Tank；2-core flow container；3-device of gel；4-water washing device；5-drying unit；6-coiler device；7-
Plasma producing apparatus；8-plasma processing apparatus；9-air-blast device；10-spinneret；11, the driven haulage gear of 12-；
13-actively haulage gear；14-heater, 15-oxygen access port.
Detailed description of the invention
The preparation method of hollow fibre membrane for purifying blood as shown in Figure 1, including dosing, spray webbing, gelation, washes, dries
Dry, receipts silk, it is characterised in that: described dosing includes preparation and the preparation of core liquid of spinning liquid, and described spinning liquid is by macromolecule
Polymer, organic solvent, additive, biocompatible materials mix at a temperature of 80-120 degree Celsius, stir formation homogeneously
Solution, spinning liquid by high molecular polymer, organic solvent, additive, biocompatibility functional polymer in mass ratio: macromolecule
Polymer: organic solvent: additive: biocompatible materials=11:25-30:1.5-2:2-3；Described high molecular polymer is
At least one in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide and the blend of SPSF, in mass ratio
For: at least one in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide: SPSF=8-12:1, preferably 9.5-
10.5:1.Described organic solvent is at least one in dimethyl acetylamide, N-methyl pyrrolidone；Described additive
There is at least one in pore effect, specially polyvinylpyrrolidone, Polyethylene Glycol, hydroxy kind cellulose；Described life
Thing compatibility material includes one or both the mixing in polyvinyl alcohol and polyethylene glycol oxide；Described core liquid solvent is
At least one in DMAc, DMF, DMSO, NMP.It is then passed through vacuumizing and defoaming and processes prepared；Described core liquid is core liquid solvent
Solution with concentration 0wt%-50wt% that water is uniformly mixed to prepare；The film silk of spinning head ejection, after gelation, washing, is carried out
Oxygen plasma processes 10-20s, then carries out drying, receiving silk operation.
For realizing the special equipment of above-mentioned preparation method, it is characterised in that include spinning liquid material-compound tank 1, core flow container 2, spray
Filament plate 10, device of gel 3, water washing device 4, drying unit 5, coiler device 6, set between described water washing device 4 and drying unit 5
Aerobic plasma processing apparatus 8.The structure of described spinning liquid material-compound tank 1 is: be provided with tank body, tank body be provided with charging aperture,
Discharging opening and heater, be provided with agitator in tank body；The structure of described core flow container is: being provided with tank body, tank body is provided with charging
Mouth and discharging opening, be provided with agitator in tank body；Described spinneret is inserting pipe-type porous spinneret；Described device of gel
Structure is: be provided with gel box, and gel box is provided with film silk entrance, film silk exports, the temperature inside the box controls device and (freezes, heats dress
Put) and case humidity control device (sprayer unit and fog-spray nozzle), gel box is interior is provided with break-in guide reel 11 through bearing.Described
The structure of water washing device be: being provided with water washing chamber, water washing chamber top is provided with film silk entrance and the outlet of film silk, through bearing in water washing chamber
Being provided with actively guide reel 13, water washing chamber is externally provided with the driving motor being connected with active guide reel 13, water washing chamber internal upper part and bottom
It is provided with break-in guide reel respectively through bearing.From figure 2 it can be seen that the film silk entrance of the film silk exit of gel box and water washing chamber
Locate warp beam respectively to hold and be provided with break-in guide reel 12, film silk is played support, guide effect, it is to avoid with gel box and the limit of water washing chamber
Edge scratching.Being provided with water circulating pump, water circulating pump water inlet connects with bottom water washing chamber, and water circulating pump outlet exports one with film silk
The water washing chamber connection of side；The structure of described drying unit 5 is: be provided with drying baker, and the casing both sides of drying baker are respectively equipped with
Film silk entrance and the outlet of film silk, in drying baker, be provided with film silk carrying roller between film silk entrance and the outlet of film silk, be provided with below film silk carrying roller
Heater 14, is provided with air-blast device 9 below heater 14, heretofore described air-blast device is below heater
Being provided with fan, drying baker is provided with the fan electromotor of the fan work that is connected with fan, drives；The structure of described coiler device
Being: be provided with support that support is provided with wire wrapping wheel, wire wrapping wheel side is provided with device of rotation driving, device of rotation driving concrete
Structure is: take-up roll one end is provided with the driven pulley being coaxial therewith, and is provided with motor, motor output shaft through actuating unit with driven
Wheel is connected；The structure of described oxygen plasma treatment device 8 is: be provided with treatment box, treatment box is respectively equipped with film silk entrance and
Film silk exports, and is provided with oxygen intake 15 and plasma generator 7 in treatment box；In treatment box, film silk entrance and the outlet of film silk
Between be provided with film silk carrying roller.Agitator in the heretofore described heater in spinning liquid material-compound tank, agitator, core flow container,
The temperature inside the box in gel box controls device and case humidity control device, the water circulating pump of water washing device, plasma fill
Put, heater in drying baker is connected with master controller with the control panel such as air-blast device, device of rotation driving；Center is controlled
The operation of each equipment of device centralized Control processed.Heretofore described coiler device is provided with stress induction device, enumerator and warning
Device.Wire wrapping wheel is made to remain the tension winding of setting, it is ensured that film silk is wound with constant rate of speed.Device to be counted reaches setting value
After, alarm equipment alarm, the film silk on wire wrapping wheel is removed.
When the special equipment of the present invention works, in spinning liquid material-compound tank and core flow container, prepare spinning liquid and core liquid respectively,
Preliminary gel forming in the film silk device of gel of spinning head ejection, by solvent eluting in water washing device；For improving the parent of film
Aqueous, film silk need to enter plasma process system, carries out oxygen plasma treatment；Plasma treatment causes the shape of hydroxyl free radical
Become, because the impact of hydroxyl free radical, the meeting grafting of film surface comprises the hydrophilic radical of-OH.In plasma treatment appts
First being passed through oxygen, open plasma processing apparatus after 3-5min, setting process voltage is 10-as 50-100V, process time
20s.Plasma treated film silk enters drying unit and dries, and finally by coiler device, winds bunchy.
Hollow fibre membrane for purifying blood hydrophilic and anticoagulant property that the method for the employing present invention is prepared have obtained significantly
Raising；Use assembly of the invention to realize said method, make hollow fibre membrane for purifying blood preparation flow integrated, automatically
Change, significantly simplify production procedure, reduce production difficulty, established technical foundation for large-scale industrial production.
The effect of the present invention is better understood when by following examples comparative.
Example 1
The hollow fibre membrane for purifying blood that a kind of Kynoar and SPSF are blended, its spinning liquid is prepared by following mass ratio
Forming, dimethyl acetylamide selected by Kynoar 20 parts, SPSF 2 parts, polyvinylpyrrolidone 8 parts, solvent
(DMAc) 70 parts.The raw material chosen is put in Agitation Tank 1, stirs at 100 DEG C 15 hours and form homogeneous phase solution；Take out
After vacuum defoamation 12h, sent in spinneret 10 by dosing pump at 70 DEG C, simultaneously by DMAc core liquid that concentration is 30wt% by counting
Amount pump is also fed in spinneret 10.After in spinneret 10, the film silk of ejection enters device of gel 3, through drawing of haulage gear 11,12
Lead entrance water washing device 4.By active haulage gear 13, and driven haulage gear below, film silk in water washing device in V
Type moves.After sufficiently washing, entering drying unit 5, the moisture in film silk is through high temperature evaporation with after air-drying, at winding
Receiving silk on device 6, winding tension is set to 5.0N.Gained perineurium is assembled into dialyser, surveys its water ultrafiltration rate, clotting time and film
Inner surface platelet adhesion amount (tally function using ultramicroscope records), concrete outcome is shown in Table 1.
Example 2
A kind of Kynoar hollow fibre membrane for purifying blood, its spinning liquid is formulated by following mass ratio, Kynoar
20 parts, SPSF 2 parts, polyvinylpyrrolidone 8 parts, polyvinyl alcohol 4 parts, solvent select dimethyl acetylamide (DMAc)
66 parts.
The raw material chosen is put in Agitation Tank 1, stirs at 100 DEG C 15 hours and form homogeneous phase solution；Evacuation takes off
After bubble 12h, sent in spinneret 10 by dosing pump at 70 DEG C, also by DMAc core liquid that concentration is 30wt% by dosing pump simultaneously
Send in spinneret 10.After in spinneret 10, the film silk of ejection enters device of gel 3, through leading into of haulage gear 11,12
Water washing device 4.By active haulage gear 13, and driven haulage gear below, film silk is V-shaped fortune in water washing device
Dynamic.After sufficiently washing, entering drying unit 5, the moisture in film silk is through high temperature evaporation with after air-drying, at coiler device
Receiving silk on 6, winding tension is set to 5.0N.Gained perineurium is assembled into dialyser, surveys in its water ultrafiltration rate, clotting time and film
Surface platelet adhesion amount (tally function using ultramicroscope records), concrete outcome is shown in Table 1.
Example 3
A kind of Kynoar hollow fibre membrane for purifying blood, its spinning liquid is formulated by following mass ratio, Kynoar
20 parts, SPSF 2 parts, polyvinylpyrrolidone 8 parts, polyvinyl alcohol 4 parts, solvent select dimethyl acetylamide (DMAc)
66 parts.The raw material chosen is put in Agitation Tank 1, stirs at 100 DEG C 15 hours and form homogeneous phase solution；Vacuumizing and defoaming
After 12h, sent in spinneret 10 by dosing pump at 70 DEG C, the DMAc core liquid that concentration is 30wt% is also sent by dosing pump simultaneously
Enter in spinneret 10.In spinneret 10, the film silk of ejection enters after device of gel 3, leads into water through haulage gear 11,12
Cleaning device 4.By active haulage gear 13, and driven haulage gear below, film silk is V-shaped motion in water washing device.
After sufficiently washing, enter plasma processing apparatus, be first passed through oxygen in plasma processing apparatus, open after 3-5min
Opening plasma processing apparatus power supply, set process voltage as 50V, the process time is controlled by the speed changing spinning, spins
Silk speed is set to 15m/min.The film silk processed through oxygen plasma enters drying unit 5, and the moisture in film silk is through high temperature
After evaporating and air-drying, receiving silk on coiler device 6, winding tension is set to 5.0N.
Gained perineurium is assembled into dialyser, surveys its blood ultrafiltration rate, clotting time and film inner surface platelet adhesion amount and (make
Record by the microscopical tally function of electronics), concrete outcome is shown in Table 1.
Example 3 quantitatively with the addition of SPSF, polyvinyl alcohol, at oxygen plasma in common spinning liquid component
Reason, hydrophilic and the blood compatibility of gained film silk are greatly improved.
Table 1: the film properties data of different embodiments
Claims (8)
1. a preparation method for hollow fibre membrane for purifying blood, including dosing, spray webbing, gelation, washes, dries, receives silk, its
Being characterised by: described dosing includes preparation and the preparation of core liquid of spinning liquid, described spinning liquid is by high molecular polymer, organic
Solvent, additive, biocompatible materials mix within specified temperatures, stir formation homogeneous phase solution, are then passed through evacuation
Deaeration processes and prepares；Described core liquid is the solution of concentration 0wt%-50wt% that core liquid solvent is uniformly mixed to prepare with water；Spray webbing
The film silk of head ejection, after gelation, washing, carries out oxygen plasma and processes 10-20s, then carries out drying, receiving silk operation.
The preparation method of hollow fibre membrane for purifying blood the most according to claim 1, it is characterised in that described macromolecule
Polymer is the blend of at least one in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide and SPSF；Institute
The organic solvent stated is at least one in dimethyl acetylamide, N-methyl pyrrolidone；Described additive is polyethylene
At least one in ketopyrrolidine, Polyethylene Glycol, hydroxy kind cellulose；Described biocompatible materials include polyvinyl alcohol and
One or both mixing in polyethylene glycol oxide.
The preparation method of hollow fibre membrane for purifying blood the most according to claim 1 and 2, it is characterised in that described high score
At least one and SPSF in polysulfones in sub-polymer, polyether sulfone, Kynoar, polylactic acid, polyamide are by quality
Ratio is: at least one in polysulfones, polyether sulfone, Kynoar, polylactic acid, polyamide: SPSF=8-12:1.
The preparation method of hollow fibre membrane for purifying blood the most according to claim 3, it is characterised in that described spinning liquid
By high molecular polymer, organic solvent, additive, biocompatibility functional polymer in mass ratio: high molecular polymer: organic
Solvent: additive: biocompatible materials=11:25-30:1.5-2:2-3 prepares.
The preparation method of hollow fibre membrane for purifying blood the most according to claim 3, it is characterised in that described core liquid is molten
Agent is at least one in DMAc, DMF, DMSO, NMP.
6. for realizing the special equipment of preparation method described in claim 1, it is characterised in that be used for above-mentioned preparation method
And special equipment: include that spinning liquid material-compound tank, core flow container, spinneret, device of gel, water washing device, drying unit, winding fill
Put, it is characterised in that between described water washing device and drying unit, be provided with oxygen plasma processing means.
Special equipment the most according to claim 6, it is characterised in that the structure of described spinning liquid material-compound tank is: be provided with tank
Body, tank body is provided with charging aperture, discharging opening and heater, is provided with agitator in tank body；The structure of described core flow container is: be provided with
Tank body, tank body is provided with charging aperture and discharging opening, is provided with agitator in tank body；Described spinneret is inserting pipe-type porous spray webbing
Plate；The structure of described device of gel is: be provided with gel box, and gel box is provided with film silk entrance, the outlet of film silk, the temperature inside the box control
Device processed and case humidity control device；The structure of described water washing device is: be provided with water washing chamber, and water washing chamber top is provided with film silk
Entrance and the outlet of film silk, water washing chamber internal upper part and bottom warp beam respectively is held and is provided with break-in guide reel, is provided with water circulating pump, recirculated water
Pumping into the mouth of a river to connect with bottom water washing chamber, water circulating pump outlet connects with the water washing chamber of film silk outlet side；Described drying
The structure of device is: be provided with drying baker, and drying baker is respectively equipped with film silk entrance and the outlet of film silk, and drying baker is interior, film silk entrance
And it is provided with film silk carrying roller between the outlet of film silk, it is provided with heater below film silk carrying roller, below heater, is provided with air-blast device；Institute
The structure of the coiler device stated is: be provided with support, and support is provided with wire wrapping wheel, and wire wrapping wheel side is provided with device of rotation driving；
The structure of described oxygen plasma treatment device is: be provided with treatment box, and treatment box is respectively equipped with film silk entrance and the outlet of film silk,
Oxygen intake and plasma generator it is provided with in treatment box.
Special equipment the most according to claim 7, it is characterised in that the described heater in spinning liquid material-compound tank, stirring
Agitator in device, core flow container, the temperature inside the box in gel box control device and case humidity control device, the following of water washing device
Heater in ring water pump, plasma generator, drying baker and the control panel such as air-blast device, device of rotation driving with in
Heart controller is connected.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107511082A (en) * | 2017-10-09 | 2017-12-26 | 李亮 | A kind of PES hollow cored fibre dialysis membrane and preparation method thereof |
| CN112791600A (en) * | 2021-02-24 | 2021-05-14 | 成都创合丰生物科技有限公司 | A hemodialysis membrane production line |
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| CN103301759A (en) * | 2013-06-22 | 2013-09-18 | 威海威高血液净化制品有限公司 | Polysulfone hollow fiber dialysis membrane and preparation method thereof |
| CN103796744A (en) * | 2011-09-15 | 2014-05-14 | 三菱丽阳株式会社 | Method for manufacturing porous hollow fiber film |
| CN206351002U (en) * | 2016-07-10 | 2017-07-25 | 威海威高血液净化制品有限公司 | A kind of hollow fibre membrane for purifying blood special equipment |
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| CN112791600A (en) * | 2021-02-24 | 2021-05-14 | 成都创合丰生物科技有限公司 | A hemodialysis membrane production line |
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Application publication date: 20160928 |