CN105943609A - 一种治疗鼻炎的中药外用制剂及其制备方法 - Google Patents
一种治疗鼻炎的中药外用制剂及其制备方法 Download PDFInfo
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Abstract
本发明公开一种治疗鼻炎的中药外用制剂及其制备方法,所述中药外用制剂按重量份计包括以下组分:细辛1~6份、辛夷花8~12份、苍耳子6~20份、鹅不食草3~8份、儿茶1~6份、桃儿七15~20份、冰片7~15份。本发明治疗鼻炎的中药外用制剂采用纯天然绿色药物,使用方便,直达病灶吸收快,作用效果强,无激素类毒副作用,安全可靠,对各种类型鼻炎具有显著的治疗效果,治疗周期短,复发率低。
Description
技术领域
本发明涉及中药制剂技术领域,尤其涉及一种治疗鼻炎的中药外用制剂及其制备方法。
背景技术
气温骤变,鼻腔来不及适应气温的骤变,易引发急性鼻炎 ;不良的生活习惯,经常拔鼻毛,挖鼻子导致鼻腔皮肤破损和毛囊损伤而引发鼻炎 ;用药不当,由于滴鼻静等药物含有鼻粘膜血管收缩成分,会引发鼻粘膜的慢性中毒反应 ;当工作或者生活环境处于干燥,粉尘或有毒物质污染的状态下,如汽车尾气,装饰材料和食品添加剂等,鼻腔黏膜受到刺激和损害 ;年气温逐年上升,空调的普及,是引发过敏性鼻炎的主要原因。
鼻炎即鼻腔炎性疾病,是病毒、细菌、变应原、各种理化因子以及某些全身性疾病引起的鼻腔黏膜的炎症。鼻炎的主要病理改变是鼻腔黏膜充血、肿胀、渗出、增生、萎缩或坏死等。鼻炎典型的病症通常表现为鼻塞、流涕、打喷嚏、鼻炎类型头痛、头昏等。鼻炎不单只是影响鼻子,长期间歇性或交替性鼻塞,会导致头晕脑胀,影响睡眠、工作和学习,而且鼻涕常会倒流入咽腔,出现咳嗽、多痰。
西医认为鼻炎为感染病毒、病菌所致,常采取的治疗为应用抗生素杀菌消炎、手术、激光等,虽能见效快,但痛苦大、治标不治本,易复发、且医疗费用高。
中医认为鼻为肺之外窍,肺开窍于鼻,肺气充沛则呼吸通利,鼻炎、鼻窦炎其病源在“肺”,多因脾肺虚弱,肺气不足至卫外不固,易感外邪。脾虚则运化失职,痰湿滞留,困结鼻窍,浸淫鼻窦粘膜而成鼻渊,常采取的中药外用制剂虽然毒副作用小,但是治疗效果低、治疗周期长、复发率高。
因此,现有技术还有待于改进和发展。
发明内容
鉴于上述现有技术的不足,本发明的目的在于提供一种治疗鼻炎的中药外用制剂及其制备方法,旨在解决现有中药外用制剂存在治疗效果低、治疗周期长及复发率高的问题。
本发明的技术方案如下:
一种治疗鼻炎的中药外用制剂,其中,按重量份计包括以下组分:细辛1~6份、辛夷花8~12份、苍耳子6~20份、鹅不食草3~8份、儿茶1~6份、桃儿七15~20份、冰片7~15份。
所述的治疗鼻炎的中药外用制剂,其中,按重量份计包括以下组分:细辛2~6份、辛夷花9~11份、苍耳子10~15份、鹅不食草6~8份、儿茶1~3份、桃儿七18~20份、冰片7~9份。
所述的治疗鼻炎的中药外用制剂,其中,按重量份计由以下组分组成:细辛2份、辛夷花10份、苍耳子15份、鹅不食草8份、儿茶2份、桃儿七20份、冰片8份。
所述的治疗鼻炎的中药外用制剂,其中,按重量份计由以下组分组成:细辛6份、辛夷花8份、苍耳子16份、鹅不食草5份、儿茶6份、桃儿七17份、冰片7份。
所述的治疗鼻炎的中药外用制剂,其中,按重量份计由以下组分组成:细辛4份、辛夷花12份、苍耳子6份、鹅不食草7份、儿茶5份、桃儿七18份、冰片10份。
一种如上任一所述的治疗鼻炎的中药外用制剂的制备方法,其中,包括步骤:按照上述配方,取鹅不食草,洗涤去除杂质捣烂取汁;取桃儿七茎和根部,用900~1000份黄酒煎熬50~70分钟后去渣取汤;取苍耳子置于炒制容器内,用中火加热,炒至表面深黄色刺焦,内部浅黄色时取出,碾去刺筛净捣碎取汁;另外将辛夷花、儿茶、细辛、冰片分别碾碎成粉末,然后加入前述制作成的药液当中混搅均匀后用棉筛滤渣,得到中药外用制剂。
所述的治疗鼻炎的中药外用制剂的制备方法,其中,取桃儿七茎和根部,用黄酒煎熬60分钟后去渣取汤。
有益效果:本发明的中药外用制剂采用纯天然绿色药物制成,使用方便,直达病灶吸收快,作用效果强,无激素类毒副作用,安全可靠,对各种类型鼻炎具有显著的治疗效果,治疗周期短,复发率低。
具体实施方式
本发明提供一种治疗鼻炎的中药外用制剂及其制备方法,为使本发明的目的、技术方案及效果更加清楚、明确,以下对本发明进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。
本发明的一种治疗鼻炎的中药外用制剂较佳实施例,其中,按重量份计包括以下组分:细辛1~6份、辛夷花8~12份、苍耳子6~20份、鹅不食草3~8份、儿茶1~6份、桃儿七15~20份、冰片7~15份。本发明的中药外用制剂采用纯天然绿色药物制成,使用方便,直达病灶吸收快,作用效果强,无激素类毒副作用,安全可靠,对各种类型鼻炎具有显著的治疗效果,治疗周期短,复发率低。
本发明的一种治疗鼻炎的中药外用制剂另一较佳实施例,其中,按重量份计包括以下组分:细辛2~6份、辛夷花9~11份、苍耳子10~15份、鹅不食草6~8份、儿茶1~3份、桃儿七18~20份、冰片7~9份。采用上述优选配方,制成的中药外用制剂治疗效果更强,治疗周期更短,复发率更低。
本发明的一种治疗鼻炎的中药外用制剂又一较佳实施例,其中,按重量份计由以下组分组成:细辛2份、辛夷花10份、苍耳子15份、鹅不食草8份、儿茶2份、桃儿七20份、冰片8份。采用上述优选配方,制成的中药外用制剂治疗效果得到进一步更强,且治疗周期更短,复发率更低。
本发明的一种治疗鼻炎的中药外用制剂又一较佳实施例,其中,按重量份计由以下组分组成:细辛6份、辛夷花8份、苍耳子16份、鹅不食草5份、儿茶6份、桃儿七17份、冰片7份。采用上述优选配方,制成的中药外用制剂同样具有治疗效果强,治疗周期短,复发率低的优异性能。
本发明的一种治疗鼻炎的中药外用制剂又一较佳实施例,其中,按重量份计由以下组分组成:细辛4份、辛夷花12份、苍耳子6份、鹅不食草7份、儿茶5份、桃儿七18份、冰片10份。采用上述优选配方,制成的中药外用制剂同样具有治疗效果强,治疗周期短,复发率低的优异性能。
本发明所述细辛,取自马兜铃科植物北细辛、汉城细辛或华细辛的干燥根和根茎;所述细辛的功效为:解表散寒,祛风止痛,通窍,温肺化饮;所述细辛主治风寒感冒,头痛,牙痛,风湿痹痛,鼻渊,肺寒咳嗽。
本发明所述辛夷花,又名木笔花、望春花、玉兰花、木兰花、紫玉兰、玉树、玉堂春,其为落叶乔木植物。辛夷的花蕾,性温味辛、归肺、胃经。因它辛散温通、芳香走窜、上行头面、善通鼻窍、因治鼻渊头痛要药,同时只要适当配量,其偏寒偏热均可应用,药用价值颇高,内服外用都有较好的疗效。
本发明所述苍耳子,属菊科、苍耳属一年生草本菊科植物苍耳的带总苞的果实,苍耳子属于中草药,具有散风除湿通窍等功效。
本发明所述鹅不食草,菊科天胡荽属植物,其味辛性温,归肺经。所述鹅不食草具有发散风寒,通鼻窍,止咳,解毒,止痒等功效。所述鹅不食草味辛烈,气辛熏,性升散,能通肺经,上达头脑,故痰喘,气闭不通,鼻塞鼻痔,胀闷不利,去目中翳障,并头中寒邪、头风脑痛疾,皆取辛温升散之功也。
本发明所述儿茶,为豆科植物儿茶的去皮枝、干的干燥煎膏。冬季采收枝、干,除去外皮,砍成大块,加水煎煮,浓缩,干燥。豆科植物儿茶分布于云南南部地区,海南有栽培。所述儿茶具有活血止痛,止血生肌,收湿敛疮,清肺化痰的功效。用于跌扑伤痛,外伤出血,吐血衄血,疮疡不敛,湿疹、湿疮,肺热咳嗽。
本发明所述桃儿七,属于“太白七药”之一,具有神奇的抗癌作用。根茎、须根、果实均可人药。根茎能除风湿,利气血、通筋、止咳;果能生津益胃、健脾理气、止咳化痰、麻木、月经不调等症均有疗效。根、根状茎:利气活血,止痛,止咳,祛风除湿。根、根状茎用于风湿痹痛,咳喘,跌打损伤,月经不调。果实:甘,平,活血通经,止咳平喘,健脾理气。果实用于劳伤咳喘,腰痛,月经不调,胎盘不下,带下病,宫颈癌。
本发明所述冰片味辛、苦,微寒;归心、肝、肺经;清香宣散,具有开窍醒神,清热散毒,明目退翳的功效,主治热病高热神昏,中风痰厥惊痫,暑湿蒙蔽清窍,喉痹耳聋,口疮齿肿,疮痈疳痔,目赤肿痛,翳膜遮睛。
中医药对治疗鼻炎疗效可靠,毒副作用小,其是从根本上进行治疗。本发明中药外用制剂,可以避免受内服药物潜在的毒性,药物直接作用于鼻腔,避免了激光,手术和等离子给鼻腔带来的创伤,只需在鼻腔内涂抹药液,不吃药,不打针,药效作用明显。
基于上述中药外用制剂,本发明还提供一种如上任一所述的治疗鼻炎的中药外用制剂的制备方法,其包括步骤:按照上述配方,取新鲜鹅不食草,洗涤去除杂质捣烂取汁;取桃儿七茎和根部,用900~1000份(如,1000份)黄酒煎熬50~70分钟(如,60分钟)后去渣取汤;取苍耳子置于热炒制容器内,用中火加热,炒至表面深黄色刺焦,内部浅黄色时取出,碾去刺筛净捣碎取汁;另外四味药剂组成材料辛夷花、儿茶、细辛、冰片分别碾碎成粉末,然后加入前述制作成的药液当中混搅均匀后用棉筛滤渣即制成中药外用制剂。
下面对本发明的中药外用制剂的使用方法进行说明:首先使用纯净水或生理盐水清洗干净鼻腔,然后用棉球吸收干燥鼻腔里面的水分,最后使用推送软管将所述中药外用制剂涂搽进鼻腔内部粘黏吸收。
用法与用量:取适量上述的外用中药制剂均匀地涂抹进鼻腔黏膜,一小时后清洗干净鼻腔吸收后的残留药物。相隔一天使用一次,一周为一个疗程,两次用药后即可明显改善症状,二个疗程即可治愈各种急慢性鼻炎。
本发明中,使用的上述中药原生药材是目前正规药店或者医院已预处理的中药材,它们可以直接进行配制本发明的中药外用制剂。中药材前处理是根据原药材或饮片的具体性质,将其经适当的清洗、浸润、切制、选制、炒制、干燥等加工步骤,加工成具有一定质量规格的中药材中间品或半成品。
通常植物药和动物药掺杂各种杂质,矿物药常夹有泥砂等,因此通过挑选、筛选、风选、洗、漂等方法除去各种杂质,通过去茎、去根、去枝梗、去粗皮、去壳、去毛、去核等方法除去非药用部位。
本发明所述治疗鼻炎的中药外用制剂依据“君臣佐使”配方原则进行配制。《内经、大沦》书中谓,主病之药为君,佐君之药谓臣,应臣之药谓使。本发明根据这个配方原则,以气、血、阴、阳为主方基础提出的方剂,该方剂是中医之复方,是从多角度制方的,以适应病症的错综复杂性以及人体自身的诸多特点。
与现有技术相比,本发明具有如下的优点:本发明所述治疗鼻炎的中药外用制剂采用纯天然绿色药物,价格低廉;使用方便,无激素类毒副作用,还可提高机体免疫力,减少复发;安全可靠,疗效显著,对鼻炎有良好的治疗效果。中药外用制剂无需激光,手术和等离子带有创伤的治疗,只需在鼻腔内涂抹药液,不吃药,不打针,配合中药验方,短期内能恢复鼻腔的正常运转功能。
临床试验及试验结果
1、选择150例内含过敏性鼻炎、鼻窦炎、鼻息肉、鼻甲肥大、嗅觉障碍等患者进行临床观察治疗,其中男性89例,女性61例,年龄最大75周岁,最小3周岁。
2、全部病例临床表现的症状主要为:清涕、鼻塞、鼻痒、间歇性喷嚏,伴有头痛、头晕、眼睛发痒。
3、疗效判定标准:
(1) 治愈:上述鼻炎症状全部消失,且一切辅助检查指标正常;
(2) 好转:上述鼻炎症状大部分消失,且大部分辅助检查指标正常;
(3) 有效:上述鼻炎症状个别消失,且个别辅助检查指标正常;
(4) 无效:上述鼻炎症状和辅助检查指标均无明显改善或者加重。
4、治疗方法:相隔一天晚饭后将所述治疗鼻炎的中药外用制剂涂抹进鼻腔内部,1小时后清洗鼻孔。一周为一个疗程,总共2个疗程。
5、治疗结果:临床治愈123例,占82%;好转16例,占10.7%;有效8例,占5.3%;无效3例,占2%。总有效率98%。从上述临床试验结果可以看出,本发明所述治疗鼻炎的中药外用制剂治疗鼻炎的总有效率高达 98%,疗效显著,无副作用,安全性高,是一种理想有效的治疗鼻炎的药物。
综上所述,本发明的一种治疗鼻炎的中药外用制剂及其制备方法,所述中药外用制剂按重量份计包括以下组分:细辛1~6份、辛夷花8~12份、苍耳子6~20份、鹅不食草3~8份、儿茶1~6份、桃儿七15~20份、冰片7~15份。本发明治疗鼻炎的中药外用制剂采用纯天然绿色药物,使用方便,直达病灶吸收快,作用效果强,无激素类毒副作用,安全可靠,对各种类型鼻炎具有显著的治疗效果,治疗周期短,复发率低。
应当理解的是,本发明的应用不限于上述的举例,对本领域普通技术人员来说,可以根据上述说明加以改进或变换,所有这些改进和变换都应属于本发明所附权利要求的保护范围。
Claims (7)
1.一种治疗鼻炎的中药外用制剂,其特征在于,按重量份计包括以下组分:细辛1~6份、辛夷花8~12份、苍耳子6~20份、鹅不食草3~8份、儿茶1~6份、桃儿七15~20份、冰片7~15份。
2.根据权利要求1所述的治疗鼻炎的中药外用制剂,其特征在于,按重量份计包括以下组分:细辛2~6份、辛夷花9~11份、苍耳子10~15份、鹅不食草6~8份、儿茶1~3份、桃儿七18~20份、冰片7~9份。
3.根据权利要求1所述的治疗鼻炎的中药外用制剂,其特征在于,按重量份计由以下组分组成:细辛2份、辛夷花10份、苍耳子15份、鹅不食草8份、儿茶2份、桃儿七20份、冰片8份。
4.根据权利要求1所述的治疗鼻炎的中药外用制剂,其特征在于,按重量份计由以下组分组成:细辛6份、辛夷花8份、苍耳子16份、鹅不食草5份、儿茶6份、桃儿七17份、冰片7份。
5.根据权利要求1所述的治疗鼻炎的中药外用制剂,其特征在于,按重量份计由以下组分组成:细辛4份、辛夷花12份、苍耳子6份、鹅不食草7份、儿茶5份、桃儿七18份、冰片10份。
6.一种如权利要求1~5任一所述的治疗鼻炎的中药外用制剂的制备方法,其特征在于,包括步骤:按照上述配方,取鹅不食草,洗涤去除杂质捣烂取汁;取桃儿七茎和根部,用900~1000份黄酒煎熬50~70分钟后去渣取汤;取苍耳子置于炒制容器内,用中火加热,炒至表面深黄色刺焦,内部浅黄色时取出,碾去刺筛净捣碎取汁;另外将辛夷花、儿茶、细辛、冰片分别碾碎成粉末,然后加入前述制作成的药液当中混搅均匀后用棉筛滤渣,得到中药外用制剂。
7.根据权利要求6所述的治疗鼻炎的中药外用制剂的制备方法,其特征在于,取桃儿七茎和根部,用黄酒煎熬60分钟后去渣取汤。
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CN201610440969.XA Pending CN105943609A (zh) | 2016-06-20 | 2016-06-20 | 一种治疗鼻炎的中药外用制剂及其制备方法 |
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CN107334991A (zh) * | 2017-08-18 | 2017-11-10 | 刘大林 | 一种治疗鼻炎的中药及制备方法 |
WO2017219846A1 (zh) * | 2016-06-20 | 2017-12-28 | 东莞市乐堂医疗投资有限公司 | 一种治疗鼻炎的中药外用制剂及其制备方法 |
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CN110559429B (zh) * | 2019-10-22 | 2022-10-18 | 福建德康宝生物科技有限公司 | 一种蜗牛酶鼻炎膏及其制备方法 |
CN113080546B (zh) * | 2021-03-31 | 2023-12-08 | 成都华神科技集团股份有限公司 | 一种治疗和/或预防鼻炎的口罩及其制备方法 |
Citations (3)
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CN102988949A (zh) * | 2012-12-06 | 2013-03-27 | 刘春秀 | 一种治疗鼻炎的药剂 |
CN105287772A (zh) * | 2015-11-03 | 2016-02-03 | 北京科炎堂生物科技有限公司 | 治疗鼻炎的中药抑菌粉及制备方法 |
CN105560372A (zh) * | 2016-03-22 | 2016-05-11 | 泰山医学院 | 一种治疗鼻炎的中药喷雾剂及其制备方法 |
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CN101991649A (zh) * | 2009-08-11 | 2011-03-30 | 成新莲 | 一种治疗过敏性鼻炎的药物 |
CN113952380A (zh) * | 2016-06-20 | 2022-01-21 | 东莞市乐堂医疗投资有限公司 | 一种治疗鼻炎的中药组合物、中药制剂及其制备方法和应用 |
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2016
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CN102988949A (zh) * | 2012-12-06 | 2013-03-27 | 刘春秀 | 一种治疗鼻炎的药剂 |
CN105287772A (zh) * | 2015-11-03 | 2016-02-03 | 北京科炎堂生物科技有限公司 | 治疗鼻炎的中药抑菌粉及制备方法 |
CN105560372A (zh) * | 2016-03-22 | 2016-05-11 | 泰山医学院 | 一种治疗鼻炎的中药喷雾剂及其制备方法 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2017219846A1 (zh) * | 2016-06-20 | 2017-12-28 | 东莞市乐堂医疗投资有限公司 | 一种治疗鼻炎的中药外用制剂及其制备方法 |
CN107334991A (zh) * | 2017-08-18 | 2017-11-10 | 刘大林 | 一种治疗鼻炎的中药及制备方法 |
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HK1224217A1 (zh) | 2017-08-18 |
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CN113952380A (zh) | 2022-01-21 |
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