CN105943598A - 一种治疗耳朵瘙痒症的外用药及其加工工艺 - Google Patents

一种治疗耳朵瘙痒症的外用药及其加工工艺 Download PDF

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CN105943598A
CN105943598A CN201610403967.3A CN201610403967A CN105943598A CN 105943598 A CN105943598 A CN 105943598A CN 201610403967 A CN201610403967 A CN 201610403967A CN 105943598 A CN105943598 A CN 105943598A
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treating ear
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汪锦川
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Abstract

本发明涉及一种治疗耳朵瘙痒症的外用药及其加工工艺，两性霉素B20％；特比萘芬15％；伊曲康唑15％；替哨唑20％；左氧氟沙星20％；苦参5％；土槿皮5％，所述用于治疗耳朵奇痒瘙痒症的外用药品对脚癣、头癣等身体外表其他皮肤真菌性感染也是一种特效的治疗药品。本发明的有益效果为：使用方便，直接用医用棉签粘附少量本药品粉末，均匀涂抹于患处即可；直接涂抹于患处，易吸收，见效快，副作用小。

Description

一种治疗耳朵瘙痒症的外用药及其加工工艺
技术领域
本发明涉及外用药品领域，尤其涉及一种治疗耳朵瘙痒症的外用药及其加工工艺。
背景技术
耳朵奇痒、瘙痒会让人十分难受，一直以来都没有任何外用药物进行治疗，一般人们就会采用挠耳朵的方式，容易导致耳外道皮肤破损，引起细菌感染，甚至引起中耳炎；更有甚者，可能捅破耳鼓膜并引发耳内乳头状瘤。
耳朵奇痒、瘙痒的主要原因是耳内受到真菌微生物感染引起的，对于真菌性耳朵奇痒，本来只是耳内外表皮肤局部感染，但由于没有局部外用药物治疗，不得不直接口服抗真菌药物，把局部治疗变成全身性治疗，药物到达耳道外表皮肤浓度低，时间长，有事需要反复服用，副作用很大，因此，急需一种治疗耳朵奇痒、瘙痒症的特效外用药品。
发明内容
针对以上缺陷，本发明提供一种抗真菌外用特效、无不良反应。方便实用的外用药及其加工工艺。
为实现上述目的，本发明采用以下技术方案：
一种治疗耳朵瘙痒症的外用药及其加工工艺，所采用的配方及其百分比重量为：
所述用于治疗耳朵奇痒瘙痒症的外用药品对脚癣、头癣等身体外表其他皮肤真菌性感染同样是一种特效的治疗药品。
本发明所述的治疗耳朵瘙痒症的外用药及其加工工艺的有益效果为：
(1)使用方便，直接用医用棉签粘附少量本药品粉末，均匀涂抹于患处即可；
(2)直接涂抹于患处，易吸收，见效快，副作用小；
具体实施方式
本发明实施例所述的治疗耳朵瘙痒症的外用药及其加工工艺，配方中含有两性霉素B，可与敏感真菌细胞膜上的甾醇结合，损伤膜的通透性，药物浓度达到人体可耐受范围的高限时则对真菌起杀菌作用；
配方中含有的特比萘芬，对于皮肤、发和甲的致病性真菌有广泛的抗真菌活性；
配方中含有伊曲康唑，具有三唑环的合成唑类抗真菌药、抗菌谱与氟康唑相似，对深部真菌和浅表真菌均有抗菌作用。临床主要应用于深部真菌所引起的感染；配方中含有替哨唑，用于抗滴虫病、抗厌氧菌感染；
配方中含有的伊曲康唑，喹诺酮类药物中的一种，具有广谱抗菌作用，抗菌作用强，对多数肠杆菌科细菌，如大肠埃希菌、克雷伯菌属、变形杆菌属、沙门菌属、志贺菌属和流感嗜血杆菌、嗜肺军团菌、淋病奈瑟菌等革兰阴性菌有较强的抗菌活性；
配方中含有的苦参，醚提物及醇提物对金黄色葡萄球菌有较强的抑菌作用；苦参水浸剂对堇色毛癣菌、同心性毛癣菌、许兰毛癣菌、奥杜盎小芽孢癣菌等有抑制作用；
配方中含有的土槿皮，对许兰黄癣菌、絮状表皮癣菌、铁锈色小芽孢癣菌、石膏样小孢子菌和白色念珠菌即有杀菌作用。
对上述成分所采用的百分比重为：
以上本发明实施例所述的治疗耳朵瘙痒症的外用药及其加工工艺，施工步骤为：
(1)将原料分别经过研磨机研磨成350目左右的细度；
(2)利用搅拌器充分搅拌混合，装入容器。
以上实施例是本发明较优选具体实施方式的一种，本领域技术人员在本技术方案范围内进行的通常变化和替换应包含在本发明的保护范围内。

Claims (2)

1.一种治疗耳朵瘙痒症的外用药及其加工工艺，其特征在于：所采用的配方及其百分比重量为：
2.一种治疗耳朵瘙痒症的外用药及其加工工艺，其特征在于：所采用的施工步骤为：
(1)将原料分别经过研磨机研磨成350目左右的细度；
(2)利用搅拌器充分搅拌混合，装入容器。
CN201610403967.3A 2016-06-04 2016-06-04 一种治疗耳朵瘙痒症的外用药及其加工工艺 Pending CN105943598A (zh)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1887352A (zh) * 2006-07-13 2007-01-03 徐艳 治疗眼部真菌和细菌感染的组合物
CN101460060A (zh) * 2006-03-01 2009-06-17 特莱斯特拉塔公司 局部治疗焦油响应性皮肤病用的组合物和方法
CN101926876A (zh) * 2010-09-01 2010-12-29 黑龙江省亨发药业有限公司 治疗牛皮癣、各种顽癣、瘙痒症的中药药膏及其制备方法
CN103233058A (zh) * 2013-05-01 2013-08-07 苏州麦克威尔生物医药科技有限公司 一种测试抗菌药物对病原微生物敏感性的方法
CN103402510A (zh) * 2010-12-20 2013-11-20 安德鲁·图安·安·勒 用于治疗皮肤病症的组合物
CN105327049A (zh) * 2014-08-06 2016-02-17 刘海燕 一种土槿皮皮炎膏及其制备方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101460060A (zh) * 2006-03-01 2009-06-17 特莱斯特拉塔公司 局部治疗焦油响应性皮肤病用的组合物和方法
CN1887352A (zh) * 2006-07-13 2007-01-03 徐艳 治疗眼部真菌和细菌感染的组合物
CN101926876A (zh) * 2010-09-01 2010-12-29 黑龙江省亨发药业有限公司 治疗牛皮癣、各种顽癣、瘙痒症的中药药膏及其制备方法
CN103402510A (zh) * 2010-12-20 2013-11-20 安德鲁·图安·安·勒 用于治疗皮肤病症的组合物
CN103233058A (zh) * 2013-05-01 2013-08-07 苏州麦克威尔生物医药科技有限公司 一种测试抗菌药物对病原微生物敏感性的方法
CN105327049A (zh) * 2014-08-06 2016-02-17 刘海燕 一种土槿皮皮炎膏及其制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
邱保国等: "《简明中药临床实用手册》", 31 January 2012 *

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Application publication date: 20160921