CN105942996A - Hemorheology monitoring device based on carotid artery stent and method thereof - Google Patents
Hemorheology monitoring device based on carotid artery stent and method thereof Download PDFInfo
- Publication number
- CN105942996A CN105942996A CN201610394183.9A CN201610394183A CN105942996A CN 105942996 A CN105942996 A CN 105942996A CN 201610394183 A CN201610394183 A CN 201610394183A CN 105942996 A CN105942996 A CN 105942996A
- Authority
- CN
- China
- Prior art keywords
- hemorheology
- integrated circuit
- carotid stents
- monitoring device
- radio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
- A61B5/02035—Determining blood viscosity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6862—Stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6876—Blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2002/823—Stents, different from stent-grafts, adapted to cover an aneurysm
Abstract
The invention relates to a hemorheology monitoring device based on a carotid artery stent and a method thereof. The hemorheology monitoring device based on the carotid artery stent and the method thereof are characterized in that the monitoring device comprises a carotid artery stent, an integrated circuit and an external processing device; the carotid artery stent is used as an antenna, and the integrated circuit is fixedly arranged in a blood vessel of the carotid artery stent; the integrated circuit comprises an energy supplying module, a hemorheology detecting module, a storage, a data processor and a first radio-frequency receiving and dispatching module, and the energy supplying module is used for supplying power to the integrated circuit; the hemorheology detecting module transmits detected hemorheology signals to the data processor through the storage, the hemorheology signals are converted into digital signals through the data processor, and the first radio-frequency receiving and dispatching module transmits the digital signals to the external processing device through the carotid artery stent.
Description
Technical field
The present invention is about a kind of hemorheology monitoring device based on carotid stents and method thereof, relates to medical monitoring
Technical field.
Background technology
Carotid disease is situation occurred frequently in recent years, and blood vessel embolism is one of which important diseases, and Etiological is dynamic
Some lipid materials of arteries and veins inner membrance are piled up and are formed white speckle, cause lumen of artery narrow, make blood flow be obstructed, and cause cervical region to lack
Blood.Carotid atherosclerotic plaque is the performance of carotid arterial atherosclerosis, is apt to occur in common carotid artery crotch, it is now recognized that with old age
The generation of people's cerebral infarction is closely related.Its mechanism causing cerebral infarction may be: speckle increases cause neck
Tremulous pulse caliber is narrow causes intracranial Low perfusion and speckle to come off formation embolus, causes entocranial artery thromboembolism.
Clinically, by the morphology of carotid stenosis and speckle is measured, carotid atherosclerotic plaque is commented
Valency, it is judged that its hazardness.Carotid stents is the important means for the treatment of carotid artery embolism, and carotid stents gets involved operation
After completing, need to carry out periodic review.At present, carotid stents is usually independent intervention, it no longer adds any
Miscellaneous part.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide a kind of volume little, radiate little, carotid artery can be propped up simultaneously
Hemorheology monitoring device based on carotid stents that frame blood vessel rheology is monitored in real time and method thereof.
For achieving the above object, the present invention takes techniques below scheme: a kind of hemorheology based on carotid stents is supervised
Survey device, it is characterised in that this monitoring device includes a carotid stents, an integrated circuit and an external processing apparatus；
Described carotid stents uses as antenna, and described integrated circuit is fixedly installed on the Ink vessel transfusing of described carotid stents；
Described integrated circuit includes that energy supply module, hemorheology detection module, memorizer, data processor and first are penetrated
Frequently transceiver module, described energy supply module is used for as described integrated circuit；Described hemorheology detection module will
The hemorheology signal detected is through the transmission of described memorizer to described data processor, and described data processor is by blood
Rheology signal is converted into digital signal, and is propped up through described carotid artery by digital signal by described first radio-frequency (RF) receiving and transmission module
Frame is transferred to described external processing apparatus.
Further, described external processing apparatus includes launching antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, process
Device, transport module and work station, by described integrated in described transmitting sky alignment body of described second radio-frequency (RF) receiving and transmission module
Circuit transmission electromagnetic transmission energy, the described integrated circuit simultaneously and in described reception antenna receiving body is sent to external
Hemorheology signal, described second radio-frequency (RF) receiving and transmission module by the hemorheology signal that receives through described processor and biography
Defeated module sends to described work station.
Further, described carotid stents includes plural bracing structure and some longitudinal support structure, often
Bracing structure described in one is bent to form ring support by a tinsel, passes through described in adjacent two between ring support
Some described longitudinal support structure being crisscross arranged are fixing to be connected, and forms network structure after making support strut, and described neck moves
Pulsation frame is configured to by two isometric joints, and the one end often saving described support is all connected with described ic output,
The other end often saving described support is respectively arranged with insulant.
Further, described ring support uses sinusoidal configuration or sawtooth waveforms structure.
Further, described carotid stents is set to as resonant frequency f of antenna:
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure
Length, C1、C2And C3It is positive coefficient.
Further, described integrated circuit uses string configuration, and strip integrated circuit is axial along described carotid stents
Arrange.
Further, described integrated circuit uses square structure, is wrapped in its outside biological compatibility shell and uses circle
Shape structure.
Further, described integrated circuit uses loop configuration, annular integrated circuit place plane and described carotid stents
Tangent plane parallel.
A kind of monitoring method based on described hemorheology monitoring device, it is characterised in that include herein below: 1) set
Put one and include hemorheology detection module, data processor, the first radio-frequency (RF) receiving and transmission module and the blood of external processing apparatus
Liquid stream become monitoring device, wherein, external processing apparatus include reception antenna, the second radio-frequency (RF) receiving and transmission module, processor,
Transport module and work station；2) hemorheology detection module gathers the hemorheology signal of carotid stents blood vessel, and leads to
Transmit after crossing data processor processes to the first radio-frequency (RF) receiving and transmission module, first radio-frequency (RF) receiving and transmission module hemorheology to receiving
Signal is sent to external processing apparatus by antenna after being modulated；3) the carotid stents blood that reception antenna will receive
Hemorheology signal in pipe is sent to work station after the second radio-frequency (RF) receiving and transmission module is demodulated and after the process of treated device.
Due to the fact that and take above technical scheme, it has the advantage that 1, the present invention includes carotid stents, collection
Becoming circuit and external processing apparatus, integrated circuit is fixedly installed on carotid stents Ink vessel transfusing to carotid stents blood stream
Become and monitor in real time, it is possible to obtain hemorheology situation in carotid stents, by the blood stream in carotid stents
The duty of carotid stents can be monitored by varying signal effectively.2, due to the fact that and take to detect in real time
Mode, patient can understand self health status without going to hospital to do radiography, reduce cost and risk, decrease trouble
The misery of person, makes the feedback that doctor obtains more quickly effectively.3, the present invention can prop up at operative treatment implantation carotid artery
Integrated circuit is implanted, it is to avoid the misery of patient's second operation while frame.The present invention can be widely applied to carotid artery disease
In sick status monitoring.
Accompanying drawing explanation
Fig. 1 is the integrated circuit structure schematic diagram of the present invention；
Fig. 2 is the structural representation during data processor employing NRF51822 chip of the present invention；
Fig. 3 is the external processing apparatus structural representation of the present invention；
Fig. 4 is that carotid stents of the present invention uses saw tooth wave shape structural representation.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is carried out detailed description.It should be appreciated, however, that being provided only more of accompanying drawing
Understanding the present invention well, they should not be interpreted as limitation of the present invention.
As it is shown in figure 1, the hemorheology monitoring device based on carotid stents of the present invention, including a carotid stents,
One integrated circuit and an external processing apparatus；Carotid stents is used for carrying out energy and signal transmission as antenna, integrated
Circuit is fixedly installed in carotid stents, and integrated circuit includes energy supply module, hemorheology detection module, deposits
Reservoir, data processor and the first radio-frequency (RF) receiving and transmission module.Energy supply module passes through through the carotid stents as antenna
First radio-frequency (RF) receiving and transmission module receives and is radiated to internal electromagnetic wave by external processing apparatus, is collected by radio frequency energy
Mode be that on integrated circuit, miscellaneous part is powered.The hemorheology signal transmission that hemorheology detection module will detect
Storing to memorizer, hemorheology signal, from memory read data, is converted into digital signal by data processor,
And load the information such as integrated circuit ID, timestamp, by the first radio-frequency (RF) receiving and transmission module using digital signal through as carotid artery
The antenna transmission of support, to external processing apparatus, completes DATA REASONING, signal emission function, wherein, energy supply mould
Block can also use minicell, in order to directly powers for each parts on integrated circuit.It addition, hemorheology detection
When module includes whole blood viscosity detection, plasma viscosity detection, packed cell volume detection, erythrocyte sedimentation rate detection, erythrocyte electrophoresis
Between one or more in detection and the detection module such as platelet aggregation rate detection, corresponding hemorheology signal includes entirely
Blood viscosity signal, plasma viscosity signal, packed cell volume signal, erythrocyte sedimentation rate signal, erythrocyte electrophoretic time signal and blood
Platelet aggregation rate signal etc..
In a preferred embodiment, as in figure 2 it is shown, data processor can use NORDIC company to produce
NRF51822 chip.This chip ADC switched pins J6 connects hemorheology detection module, and VDD power pins J1 is even
Connecing energy supply module, XC1, XC2 pin J37-J38 connects clock circuit, VDD_PA, ANT1, ANT2 pin
J30-J32 connects the first radio-frequency (RF) receiving and transmission module, and P0.01 pin J5 connects power sense circuit, DEC1 pin J39 warp
3rd electric capacity C3 ground connection；Ground connection after VSS pin J33, J34 parallel connection, connects energy after VSS pin J33, J34 parallel connection
Amount supply module, the 4th electric capacity C4 in parallel between AVDD pin with VSS pin.DEC2 pin J29 is through the tenth
Electric capacity C10 and EXP_GND pin J49 be connected after ground connection；VSS pin J13 ground connection, SWCLK pin is through the 3rd resistance
R3 ground connection.
Wherein, clock circuit includes the first electric capacity C1, the second electric capacity C2 and crystal oscillator X1, and crystal oscillator X1 controls end pin 1
Through the second electric capacity C2 ground connection, crystal oscillator X1 outfan pin 2 is through the first electric capacity C1 ground connection；Crystal oscillator X1 controls end pin
The 1 XC1 pin J37 being additionally coupled to NRF51822 chip, crystal oscillator X1 outfan pin 2 is additionally coupled to NRF51822
The XC2 pin J38 of chip.
Power sense circuit includes the first resistance R1, the second resistance R2 and electric capacity C13, and the first resistance R1 mono-terminates height
Level (i.e. energy supply module), the first resistance R1 other end is through the second resistance R2 ground connection；It is positioned at the second resistance R2
It is connected to NRF51822 by wire between two ends shunt capacitance C13, and the first resistance R1 other end and the second resistance R2
The P0.01 pin J5 of chip.
In a preferred embodiment, as it is shown on figure 3, external processing apparatus include launch antenna, reception antenna,
Second radio-frequency (RF) receiving and transmission module, processor, transport module and work station.By the second radio-frequency (RF) receiving and transmission module emitted sky alignment
Internal integrated circuit launches electromagnetic transmission energy, simultaneously and the integrated circuit that is received in antenna receiving body is sent to body
Outer hemorheology signal；Second radio-frequency (RF) receiving and transmission module is by the treated device of hemorheology signal received, transport module
Send to work station, in case follow-up use.Wherein, work station can use smart mobile phone, intelligent watch etc. mobile eventually
End.
In a preferred embodiment, being provided with signal processing system in work station, signal processing system is according to setting
Measure the hemorheology signal obtained in time and judge whether the blood vessel being provided with carotid stents occurs restenosis, if
Within the setting time, hemorheology signal exceeds preset range, then it is assumed that the blood vessel being provided with carotid stents occurs the narrowest
Narrow, if within the time set, hemorheology signal is in preset range, then it is assumed that be provided with carotid stents
Blood vessel there is not restenosis.
In a preferred embodiment, as shown in Figure 4, carotid stents includes plural bracing structure
1 and some longitudinal support structure 2, each bracing structure 1 is bent to form ring support by a tinsel；Adjacent
Connect by some longitudinal support structure 2 being crisscross arranged are fixing between two ring supports, after making support strut, form net
Shape structure.Ring support can use sinusoidal configuration or sawtooth waveforms structure.Carotid stents is by two isometric joint supports
Constituting, the one end often saving support is all connected with ic output, two joints be configured to the two of integrated circuit antenna
Pole feeds.Wherein, it is respectively arranged with insulant at the other end often saving support, is somebody's turn to do by insulant is fixing
The steadiness of joint supporting structure.In the present embodiment, when this carotid stents is as antenna, its radiance is more preferable,
Frequency band is wider.
Carotid stents is set to as resonant frequency f of antenna:
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure
Length, C1、C2And C3It is positive coefficient.Wherein, N, n and l are the biggest, and resonant frequency is the least.During use, by
In not adjusting the size of carotid stents, so by adjusting waveform in quantity N of ring support, ring support
Length l of fluctuating quantity n and longitudinal support structure adjusts the resonant frequency of antenna.
In a preferred embodiment, integrated circuit external is enclosed with biological compatibility shell.Integrated circuit is permissible
Being fixed on outside carotid stents by a gim peg, one end of gim peg is welded on the pad of integrated circuit, another
End links together with carotid stents outer wall；Gim peg is exposed to biological compatibility enclosure, biological compatible
Property shell be avoided that produce human body rejection.Preferably, biological compatibility shell has certain pliability, permissible
Bending.The material of biological compatibility shell preferably employs polydimethylsiloxane (PDMS).During making, can be by integrated
Circuit is put in a mold, is filled with encapsulation with polydimethylsiloxane, gim peg is left outside thus prepares band
Biological compatibility shell and the integrated circuit of gim peg.
In a preferred embodiment, could be covered with biology at the solder joint of gim peg and carotid stents compatible
Property medicine film.Owing to the welding of gim peg and carotid stents may destroy the biological compatibility outside carotid stents
Shell, covers one layer of medicine film at gim peg and carotid stents weld, can prevent the rejection of human body from sending out further
Raw.
In a preferred embodiment, integrated circuit by flexible PCB and is formed on this flexible PCB by wafer
The each modular circuit chip made is made, and to adapt to volumetric constraint, and can carry out curved with the change of carotid stents shape
Song, but its length is less than carotid stents length, and in order to not block blood vessel, its sectional area less than 1mm ×
1mm。
In a preferred embodiment, integrated circuit can use string configuration, and strip integrated circuit moves along neck
Pulsation frame is axial arranged；Integrated circuit can use square structure, is wrapped in its outside biological compatibility shell and adopts
Use circular configuration；Integrated circuit can use loop configuration, annular integrated circuit place plane to cut with carotid stents
Face is parallel.
The hemorheology monitoring device based on carotid stents using the present invention is described in detail below by specific embodiment
The detailed process that the hemorheology of patient is monitored:
1, the collection of hemorheology detection module is provided with the endovascular hemorheology signal of carotid stents, and by number
Transmit after processing according to processor to the first radio-frequency (RF) receiving and transmission module, first radio-frequency (RF) receiving and transmission module hemorheology signal to receiving
It is sent to external processing apparatus by the carotid stents as antenna after being modulated.
2, the endovascular hemorheology signal being provided with carotid stents received is received by reception antenna through the second radio frequency
Send out after module is demodulated and be sent to work station after the process of treated device.
In a particular embodiment, use the hemorheology monitoring device based on carotid stents of the present invention that carotid artery is propped up
Frame duty carries out the process detected:
The vessel inner blood rheology letter being provided with carotid stents that the signal processing system being arranged in work station will receive
Number compare with preset value, if setting the hemorheology signal of time arteria carotis interna stented vessel in preset range
In, determine that carotid stents duty is good, it is believed that the blood vessel being provided with carotid stents does not occur restenosis existing
As；If the hemorheology signal in setting time arteria carotis interna stented vessel is beyond preset range, determine carotid artery
Support duty occurs abnormal, it is believed that be provided with the blood vessel generation restenosis phenomenon of carotid stents, furthermore it is possible to
Further appreciate that the work of carotid stents as reference value according to the carotid stents endovascular hemorheology signal obtained
Make situation.
The various embodiments described above are merely to illustrate the present invention, and the structure of the most each parts, connected mode and processing technology etc. are all
Can be varied from, every equivalents carried out on the basis of technical solution of the present invention and improvement, the most should not
Get rid of outside protection scope of the present invention.
Claims (9)
1. a hemorheology monitoring device based on carotid stents, it is characterised in that this monitoring device includes a neck
Arterial bracket, an integrated circuit and an external processing apparatus；
Described carotid stents uses as antenna, and described integrated circuit is fixedly installed on the blood vessel of described carotid stents
In；Described integrated circuit includes energy supply module, hemorheology detection module, memorizer, data processor and
One radio-frequency (RF) receiving and transmission module, described energy supply module is used for as described integrated circuit；Described hemorheology detection mould
The hemorheology signal detected is transmitted to described data processor by block through described memorizer, and described data processor will
Hemorheology signal is converted into digital signal, and is moved through described neck by digital signal by described first radio-frequency (RF) receiving and transmission module
Pulsation frame is transferred to described external processing apparatus.
2. hemorheology monitoring device based on carotid stents as claimed in claim 1, it is characterised in that described
External processing apparatus includes launching antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, transport module and work
Stand, described second radio-frequency (RF) receiving and transmission module described integrated circuit in described transmitting sky alignment body launch electromagnetic wave and pass
Delivery of energy, the described integrated circuit simultaneously and in described reception antenna receiving body is sent to external hemorheology signal,
The hemorheology signal received is sent to described by described second radio-frequency (RF) receiving and transmission module through described processor and transport module
Work station.
3. hemorheology monitoring device based on carotid stents as claimed in claim 1, it is characterised in that described
Carotid stents includes plural bracing structure and some longitudinal support structure, and each described cross-brace is tied
Structure is bent to form ring support by a tinsel, by some institutes being crisscross arranged between ring support described in adjacent two
Stating the fixing connection of longitudinal support structure, form network structure after making support strut, described carotid stents is by isometric two
Joint is configured to, and the one end often saving described support is all connected with described ic output, often saves the another of described support
One end is respectively arranged with insulant.
4. hemorheology monitoring device based on carotid stents as claimed in claim 3, it is characterised in that described
Ring support uses sinusoidal configuration or sawtooth waveforms structure.
5. the hemorheology monitoring device based on carotid stents as described in claim 3 or 4, it is characterised in that
Described carotid stents is set to as resonant frequency f of antenna:
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure
Length, C1、C2And C3It is positive coefficient.
Hemorheology monitoring device based on carotid stents the most as claimed in claim 1 or 2 or 3 or 4, it is special
Levying and be, described integrated circuit uses string configuration, and strip integrated circuit is axial arranged along described carotid stents.
Hemorheology monitoring device based on carotid stents the most as claimed in claim 1 or 2 or 3 or 4, it is special
Levying and be, described integrated circuit uses square structure, is wrapped in its outside biological compatibility shell and uses circle knot
Structure.
Hemorheology monitoring device based on carotid stents the most as claimed in claim 1 or 2 or 3 or 4, it is special
Levying and be, described integrated circuit uses loop configuration, annular integrated circuit place plane to cut with described carotid stents
Face is parallel.
9. based on a monitoring method for hemorheology monitoring device, its feature as described in any one of claim 1～8
It is, including herein below:
1) arrange one and include hemorheology detection module, data processor, the first radio-frequency (RF) receiving and transmission module and external treatment
The hemorheology monitoring device of equipment, wherein, external processing apparatus include reception antenna, the second radio-frequency (RF) receiving and transmission module,
Processor, transport module and work station；
2) hemorheology detection module gathers the hemorheology signal of carotid stents blood vessel, and by data processor
Transmit after reason to the first radio-frequency (RF) receiving and transmission module, after the hemorheology signal received is modulated by the first radio-frequency (RF) receiving and transmission module
It is sent to external processing apparatus by antenna；
3) endovascular for the carotid stents received hemorheology signal is entered by reception antenna through the second radio-frequency (RF) receiving and transmission module
It is sent to work station after row demodulation and after the process of treated device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610394183.9A CN105942996A (en) | 2016-06-06 | 2016-06-06 | Hemorheology monitoring device based on carotid artery stent and method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610394183.9A CN105942996A (en) | 2016-06-06 | 2016-06-06 | Hemorheology monitoring device based on carotid artery stent and method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105942996A true CN105942996A (en) | 2016-09-21 |
Family
ID=56908440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610394183.9A Pending CN105942996A (en) | 2016-06-06 | 2016-06-06 | Hemorheology monitoring device based on carotid artery stent and method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105942996A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5967986A (en) * | 1997-11-25 | 1999-10-19 | Vascusense, Inc. | Endoluminal implant with fluid flow sensing capability |
| CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
| CN104382676A (en) * | 2014-11-21 | 2015-03-04 | 清华大学深圳研究生院 | In-vivo wireless communication device based on vascular stent and wireless communication system |
| CN105193529A (en) * | 2015-10-20 | 2015-12-30 | 清华大学深圳研究生院 | In vivo wireless sensing system based on cardiovascular stent |
-
2016
- 2016-06-06 CN CN201610394183.9A patent/CN105942996A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5967986A (en) * | 1997-11-25 | 1999-10-19 | Vascusense, Inc. | Endoluminal implant with fluid flow sensing capability |
| CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
| CN104382676A (en) * | 2014-11-21 | 2015-03-04 | 清华大学深圳研究生院 | In-vivo wireless communication device based on vascular stent and wireless communication system |
| CN105193529A (en) * | 2015-10-20 | 2015-12-30 | 清华大学深圳研究生院 | In vivo wireless sensing system based on cardiovascular stent |
Non-Patent Citations (3)
| Title |
|---|
| CAN LI ET AL: "Wireless link analysis of cardiovascular stent as antenna for biotelemetry", 《SYMPOSIUM ON SIGNAL PROCESSING AND MATHEMATICAL MODELING OF BIOLOGICAL PROCESSES WITH APPLICATIONS TO CYBER-PHYSICAL SYSTEMS FOR PRECISE MEDICINE (GLOBALSIP 2015)》 * |
| 张玉兴 等: "《射频模拟电路与系统》", 30 September 2008 * |
| 魏茂元: "宏观血液流变学常用检测指标及临床意义", 《2009全国徽循环与血液流变学基础研究及临床应用学术研讨会论文》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Chow et al. | A miniature-implantable RF-wireless active glaucoma intraocular pressure monitor | |
| CN105193529A (en) | In vivo wireless sensing system based on cardiovascular stent | |
| US9662021B2 (en) | Miniature stent-based implantable wireless monitoring devices | |
| CN102422330B (en) | Wireless sensor reader | |
| CN104382676A (en) | In-vivo wireless communication device based on vascular stent and wireless communication system | |
| US20110077501A1 (en) | Micro mri unit | |
| US20130116575A1 (en) | Implantable doppler blood flow monitor and doppler probe | |
| CN105919559A (en) | Tumor impedance and blood pressure monitoring device based on abdominal aorta stent and method based on tumor impedance and blood pressure monitoring device | |
| CN110464311A (en) | A kind of velocity of blood flow monitoring device and its method based on carotid stents | |
| CN105942997A (en) | Comprehensive parameter monitoring device and method based on abdominal aortic stent | |
| CN105942998A (en) | Blood vessel wall pressure monitoring device and method based on abdominal aortic stent | |
| CN105832326A (en) | Coronary stent based blood flow speed monitoring device and coronary stent based blood flow speed monitoring method | |
| CN105942996A (en) | Hemorheology monitoring device based on carotid artery stent and method thereof | |
| CN105943007A (en) | Pressure-difference monitoring device based on carotid artery stent and method thereof | |
| CN105868577A (en) | Blood flow velocity monitoring device and method based on carotid artery stent | |
| CN105832311A (en) | Coronary stent based hemorheological monitoring device and coronary stent based hemorheological monitoring method | |
| CN105832312A (en) | Device and method for monitoring blood rheology on basis of renal arterial stent | |
| CN105852842A (en) | Blood rheology monitoring device and method based on arteria femoralis stent | |
| CN105919576A (en) | Pressure difference monitoring device based on femoral artery stent and method based on pressure difference monitoring device | |
| CN106073749A (en) | Velocity of blood flow monitoring device based on vein support and method thereof | |
| CN206355035U (en) | Hemorheology monitoring device based on renal artery stent | |
| CN105943006A (en) | Pressure-difference monitoring device based on heart coronary artery stent and method thereof | |
| CN105832313A (en) | Peripheral arterial stent based hemorheological monitoring device and peripheral arterial stent based hemorheological monitoring method | |
| CN105902259A (en) | Blood flow speed monitoring device and method based on femoral artery stent | |
| CN105832325A (en) | Renal arterial stent based blood flow speed monitoring device and renal arterial stent based blood flow speed monitoring method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160921 |
|
| RJ01 | Rejection of invention patent application after publication |