CN105919870A - Traditional Chinese medicine composition containing melia azedarach and applied to acarid killing cosmetics - Google Patents
Traditional Chinese medicine composition containing melia azedarach and applied to acarid killing cosmetics Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition containing melia azedarach and applied to acarid killing cosmetics. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 18 parts of nepeta cataria, 20 to 30 parts of melia azedarach, 10 to 15 parts of calendula officinalis, 6 to 10 parts of lonicera japonica, 2 to 5 parts of gynostemma pentaphyllum, and 6 to 9 parts of tribulus terrestris. The traditional Chinese medicine composition ensures that crude drugs produce synergistic interaction through the optimization of material combination, enhances the acarid killing effect, and is mild in drug efficacy, formed by extracting and combining pure natural plant extracts, small in side effect, wide in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of Chinese drug-treated group for acaricide worm cosmetics containing Cortex Meliae
Compound.
Background technology
Acarid belongs to the animal that a class build of Arthropoda Arachnoidea wide abdomen subclass is small, and body size the most all exists
0.5 millimeter, some little to 0.1 millimeter, most of kinds are less than 1 millimeter.It is now discovered that the healthy relation of acarid and people is very
Closely, such as gamasid, trombiculid, acaricide, compacted demodicid mite, flour mite, dust mite and Pu demodicid mite etc. can sting people and suck blood, encroach on skin, causes " distiller grains
Nose " or demodicidosis, anaphylaxis, urinary tract demodicid mite disease, pulmonary acariasis, intestinal acariasis and scabies, the serious harm mankind's is healthy.
Mention acarid, first affirmed the acarid harm to skin, be not as described in some people " acarid is normal bacteria
Group, acaricide does not affects the whole.Acarid is ' worm ', by no means ' flora ' ", it is belonging to the parasite of human of Arthropoda Arachnoidea,
Also it is a lot of harmful levels of pathogens carriers simultaneously.Adult's mite infection rate is the highest, and the skin infecting acarid shows as under normal circumstances
Lighter symptom, such as heavy wool, corse sweat pore are with blackhead, little red pimple or red papules, skin pruritus or decortication etc., severe
The infected can cause demodicid mite property acne rosacea and allergic disease.
Acarid draws nutritional labeling inside skin, stimulates blood capillary and cell tissue, causes cutaneous malignancies.Skin
Acarid accelerates the generation of fine wrinkles, accelerates the pigmentation such as chloasma, freckle, black speck, can also result in acne, pox scar, acne,
Pachylosis, cutin are thickening, form concavo-convex skin.Cutaneous mites can also be formed pruritus, acne rosacea and blush, red blood streak
Deng.
The method of existing acaricide worm has a variety of, has and directly uses compound pesticides to carry out acaricide, acaricide instant effect, but
Big, the most repeatedly to skin harm；Also having employing natural Chinese medicinal herb composition acaricide worm, side effect is little, low price, and can repair damage
Hinder skin histology, but it is slow to there is the speed that takes effect, the defect of weak effect, thus, improving Chinese medicine formula is to remove to improve its drug effect
The optimal path of acarid.
Summary of the invention
It is an object of the invention to overcome the acaricide worm weak effect existing for existing acaricide worm Chinese medicine composition, acaricide worm to see
Imitate slow deficiency, it is provided that a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae.Said composition is by optimizing
The compatibility of raw material, makes to produce between raw medicinal material synergistic function, adds the acaricide worm effect of compositions and the speed that takes effect,
Drug effect is gentle；Said composition is combined by pure natural plant extract, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of containing Cortex Meliae in acaricide worm cosmetics
Drug composition, said composition is to be prepared from by the raw material of following weight: Herba Schizonepetae 10-18 part, Cortex Meliae 20-30
Part, Flos Inulae 10-15 part, Flos Lonicerae 6-10 part, Herb Gynostemmae Pentaphylli 2-5 part, Fructus Tribuli 6-9 part.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, wherein said Herba Schizonepetae, taste is micro-
Bitter, pungent；Slightly warm in nature；Return liver, lung meridian；Have dispeling the wind, induce sweat, rash, effect of hemostasis；It is mainly used in treating cold, fever, head
Bitterly, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, skin ulcer scabies, epistaxis, spit blood, have blood in stool, metrorrhagia, puerperal blood faints.
Wherein said Cortex Meliae, bitter in the mouth, cold in nature；Return liver, spleen, stomach warp；There is parasite killing, treat effect of tinea；It is mainly used in
Treatment ascariasis, enterobiasis, abdominal pain due to worm stagnation；External treatment scabies pruritus.
Wherein said Flos Inulae, bitter in the mouth, light；Property flat；Return lung, stomach, large intestine channel；There is removing heat from blood, hemostasis, anti-inflammation
Effect；It is mainly used in treating expectorant knot in the heart, the lower distension of the side of body, cough with asthma, singultus, saliva such as shellac varnish, epigastric oppression, eructation unrelieved, big abdomen
Edema.
Wherein said Flos Lonicerae, sweet in the mouth, cold in nature；Return lung, the heart, stomach warp；Have heat-clearing and toxic substances removing, antiinflammatory, qi-restoratives treat wind
Effect, is mainly used in treating disease under distension, epidemic febrile disease heating, the disease such as pyretic toxicity carbuncle and ulcer and tumor.
Wherein said Herb Gynostemmae Pentaphylli, bitter in the mouth, sweet, cool in nature；Return lung, spleen, kidney channel；There is heat-clearing and toxic substances removing, tranquillizing and allaying excitement, improvement
Sleep, blood fat reducing, cholesterol reducing, boosting qi and nourishing yin, effect of spermatogenesis controlling nocturnal emission with astringent drugs；It is mainly used in treating body void weak；Nephrasthenia emission；In vain
Cytopenia；Hyperlipemia；Viral hepatitis；Chronic gastroenteritis；Chronic tracheitis.
Wherein said Fructus Tribuli, acrid in the mouth, hardship, slightly warm in nature；Return Liver Channel；There is suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic
Effect；Being mainly used in treatment headache dizziness, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, it is preferred that said composition be by
The raw material of following weight is prepared from: Herba Schizonepetae 12-15 part, Cortex Meliae 22-25 part, Flos Inulae 11-13 part, Flos Lonicerae
8-10 part, Herb Gynostemmae Pentaphylli 2-4 part, Fructus Tribuli 7-9 part；It is further preferred that said composition is by the raw material system of following weight
Standby: Herba Schizonepetae 14 parts, Cortex Meliae 25 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, Fructus Tribuli 8 parts.By above-mentioned
Preferably, the synergistic function that can make compositions is maximum, and acaricide worm effect reaches optimal, and side effect is minimum.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, except above-mentioned necessary raw material
Outward, auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water can also be added according to actual needs
Deng.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, can arbitrary proportion and conventional base material
Making cosmetics, State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, said composition is by multiple gentleness
Natural material is made, with Cortex Meliae as monarch drug, Herba Schizonepetae, Flos Inulae be ministerial drug, Flos Lonicerae and Fructus Tribuli be adjuvant drug, Herb Gynostemmae Pentaphylli is for making
Medicine, has synergistic function between each compatibility medical material, has the rapid osmotic acarid that enters skin thus rapid ejection is grown up, kills
Larva, pronymph, teleonymph, repair injured skin, reduces the effects such as acarid parasitic probability again, thus reaches quick acaricide worm
With the effect of lasting acaricide worm, acaricide worm is effective, and speed is fast, and drug effect is gentle, has no side effect, and is suitable for all kinds of skin quality.
Further, the invention provides the system of a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae
Preparation Method, its concrete preparation process is as follows:
1, pulverize after Herba Schizonepetae, Cortex Meliae, Flos Inulae, Flos Lonicerae, Herb Gynostemmae Pentaphylli, Fructus Tribuli being separately dried, extract and concentrate,
Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, the Herba Schizonepetae extracting solution of step 1 gained, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli are carried
Take liquid, Fructus Tribuli extract and carry out maturation process respectively, carry out after cooling filtering, purifying to obtain each raw material essence, by each raw material essence
China's liquid mix homogeneously, and again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions.
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, wherein step 1
In to Herba Schizonepetae, Cortex Meliae, Flos Inulae, Flos Lonicerae, Herb Gynostemmae Pentaphylli, the extraction of Fructus Tribuli, method for concentration are conventional plant extract, concentration
Method, can separate the effective medical active composition in plant, and increases activity component concentration, improves acaricide worm effect.
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, wherein step 2
In to Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract
Carry out maturation process respectively, i.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in extracting solution, reduce
Side effect, improves the adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight becomes the activity of molecular weight
Composition, improves the seepage velocity to skin.
Wherein, in described curing process, the cooking conditions to each raw material is different, effectively can remove in maximum guarantee
Under the reactive conditions of miticidal activities material, destroy the easy allergin in extracting solution, reduce side effect, and molecular weight is bigger
Active ingredient breaks down becomes the active component of molecular weight, improves the seepage velocity to skin, the tool of its temperature, pressure and time
Body selects as follows:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Herba Schizonepetae | 65-70 | 0.1-0.2 | 0.5-1 |
| Cortex Meliae | 75-80 | 0.1-0.2 | 1-2 |
| Flos Inulae | 60-65 | 0.1-0.2 | 0.5-1 |
| Flos Lonicerae | 65-70 | 0.1-0.2 | 0.5-1 |
| Herb Gynostemmae Pentaphylli | 70-75 | 0.1-0.2 | 0.5-1 |
| Fructus Tribuli | 65-70 | 0.1-0.2 | 0.5-1 |
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, by different material
Extracting solution ripening at different conditions, inactivates the easy allergin in raw material extracting solution or decomposes, and retaining and can work in coordination with increasing
Effective medicinal active ingredient of effect, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus
Not only reduce the allergy probability of Chinese medicine composition, improve adaptability, moreover it is possible to improve skin-permeation rate, acaricide worm effect
More preferably, faster.
Compared with prior art, beneficial effects of the present invention:
1, the present composition passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function,
Exciting the property of medicine of effective active matter greatly, acaricide worm is effective, faster.
2, the present composition selects multiple gentle raw material, and formulated by optimal compatibility, drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, to skin
Permeability more preferable, improve acaricide worm speed.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easily
Anaphylaxis and side reaction, improve the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should not understood
Scope for the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to this
The scope of invention.
Embodiment 1
1, by Herba Schizonepetae 14 parts, Cortex Meliae 25 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, after Fructus Tribuli 8 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae carry
Take liquid, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Schizonepetae essence；By the Cortex Meliae extractive liquid of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Cortex Meliae essence；By the Flos Inulae extracting solution of step 1 gained at 63 DEG C, carry out under 0.1Mpa pressure
Carry out after ripening 1h filtering, purifying, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Lonicerae essence；Strand by step 1 gained
Blue extracting solution, at 73 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Herb Gynostemmae Pentaphylli essence under 0.1Mpa pressure；Will step
The Fructus Tribuli extract of rapid 1 gained, at 68 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Fructus Tribuli under 0.2Mpa pressure
Essence；By the Herba Schizonepetae essence of gained, Cortex Meliae essence, Flos Inulae essence, Flos Lonicerae essence, Herb Gynostemmae Pentaphylli elite
Liquid, Fructus Tribuli essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, and speed is fast, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 2
1, by Herba Schizonepetae 10 parts, Cortex Meliae 20 parts, Flos Inulae 15 parts, Flos Lonicerae 6 parts, Herb Gynostemmae Pentaphylli 5 parts, after Fructus Tribuli 6 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae carry
Take liquid, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 65 DEG C, carry out after carrying out ripening 1h under 0.1Mpa pressure filtering, purifying, cold
But Herba Schizonepetae essence is obtained；By the Cortex Meliae extractive liquid of step 1 gained at 80 DEG C, carried out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purification, cool down to obtain Cortex Meliae essence；By the Flos Inulae extracting solution of step 1 gained at 65 DEG C, carry out ripe under 0.1Mpa pressure
Carry out filtering, purifying after changing 0.5h, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 65 DEG C,
Carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Lonicerae essence；Strand by step 1 gained
Blue extracting solution, at 70 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Herb Gynostemmae Pentaphylli essence under 0.1Mpa pressure；Will step
The Fructus Tribuli extract of rapid 1 gained, at 70 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Fructus Tribuli under 0.2Mpa pressure
Essence；By the Herba Schizonepetae essence of gained, Cortex Meliae essence, Flos Inulae essence, Flos Lonicerae essence, Herb Gynostemmae Pentaphylli elite
Liquid, Fructus Tribuli essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 3
1, by Herba Schizonepetae 18 parts, Cortex Meliae 30 parts, Flos Inulae 10 parts, Flos Lonicerae 10 parts, Herb Gynostemmae Pentaphylli 2 parts, after Fructus Tribuli 9 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae carry
Take liquid, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Schizonepetae essence；By the Cortex Meliae extractive liquid of step 1 gained at 75 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Cortex Meliae essence；By the Flos Inulae extracting solution of step 1 gained at 60 DEG C, carry out under 0.1Mpa pressure
Carry out after ripening 1h filtering, purifying, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 65 DEG C,
Carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Lonicerae essence；Herb Gynostemmae Pentaphylli by step 1 gained
Extracting solution, at 75 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herb Gynostemmae Pentaphylli essence under 0.2Mpa pressure；Will step
The Fructus Tribuli extract of rapid 1 gained, at 65 DEG C, carries out after carrying out ripening 1h filtering, purifying under 0.1Mpa pressure, cools down to obtain Fructus Tribuli essence
China's liquid；By the Herba Schizonepetae essence of gained, Cortex Meliae essence, Flos Inulae essence, Flos Lonicerae essence, Herb Gynostemmae Pentaphylli essence,
Fructus Tribuli essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, has no side effect, the advantage of suitable various skin skin quality.
Comparative example 1
1, by Herba Schizonepetae 14 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, Fructus Tribuli 8 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains Herba Schizonepetae extracting solution, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli carry
Take liquid；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Schizonepetae essence；By the Flos Inulae extracting solution of step 1 gained at 63 DEG C, carry out after carrying out ripening 1h under 0.1Mpa pressure
Filter, purify, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 70 DEG C, carry out under 0.2Mpa pressure
Carry out after ripening 0.5h filtering, purifying, cool down to obtain Flos Lonicerae essence；By the Herb Gynostemmae Pentaphylli extract of step 1 gained at 73 DEG C,
Carry out after carrying out ripening 1h under 0.1Mpa pressure filtering, purifying, cool down to obtain Herb Gynostemmae Pentaphylli essence；The Fructus Tribuli of step 1 gained is carried
Take liquid at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Fructus Tribuli essence；By gained
Herba Schizonepetae essence, Flos Inulae essence, Flos Lonicerae essence, Herb Gynostemmae Pentaphylli essence, Fructus Tribuli essence mix homogeneously, and again enter
Row purifies, and obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, the Chinese medicine composition for acaricide worm cosmetics obtained；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 2
1, by Herba Schizonepetae 14 parts, Cortex Meliae 25 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Fructus Tribuli 8 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Fructus Tribuli carry
Take liquid；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Schizonepetae essence；By the Cortex Meliae extractive liquid of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Cortex Meliae essence；By the Flos Inulae extracting solution of step 1 gained at 63 DEG C, carry out under 0.1Mpa pressure
Carry out after ripening 1h filtering, purifying, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Lonicerae essence；Fructus Tribuli by step 1 gained
Extracting solution, at 68 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Fructus Tribuli essence under 0.2Mpa pressure；By gained
Herba Schizonepetae essence, Cortex Meliae essence, Flos Inulae essence, Flos Lonicerae essence, Fructus Tribuli essence mix homogeneously, and again
Purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 3
1, by Herba Schizonepetae 20 parts, Cortex Meliae 15 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, after Fructus Tribuli 8 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae carry
Take liquid, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, by the Herba Schizonepetae extracting solution of step 1 gained at 68 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Schizonepetae essence；By the Cortex Meliae extractive liquid of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Cortex Meliae essence；By the Flos Inulae extracting solution of step 1 gained at 63 DEG C, carry out under 0.1Mpa pressure
Carry out after ripening 1h filtering, purifying, cool down to obtain Flos Inulae essence；By the Flos Lonicerae extractive solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Flos Lonicerae essence；Strand by step 1 gained
Blue extracting solution, at 73 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Herb Gynostemmae Pentaphylli essence under 0.1Mpa pressure；Will step
The Fructus Tribuli extract of rapid 1 gained, at 68 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Fructus Tribuli under 0.2Mpa pressure
Essence；By the Herba Schizonepetae essence of gained, Cortex Meliae essence, Flos Inulae essence, Flos Lonicerae essence, Herb Gynostemmae Pentaphylli elite
Liquid, Fructus Tribuli essence mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 4
1, by Herba Schizonepetae 14 parts, Cortex Meliae 25 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, after Fructus Tribuli 8 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae carry
Take liquid, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
2, the Herba Schizonepetae extracting solution of step 1 gained, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli are carried
Take liquid, Fructus Tribuli extract mix homogeneously, and again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the Chinese medicine for acaricide worm cosmetics containing Cortex Meliae
Compositions；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Acaricide worm cosmetics above-described embodiment 1-3 and comparative example 1-4 obtained are tried out, and randomly choosing 45 has demodicid mite
The mild skin disease volunteer that worm causes, is divided into 9 groups, and wherein 1-7 uses the cosmetic that embodiment and comparative example prepare respectively
Product, select the best acaricide worm cosmetics of commercial type for the 8th group, the 9th group for not use acaricide worm cosmetics, use 5 respectively,
10, after 15 days and suspend and use after 10 days, acaricide worm effect is detected and evaluates, records as follows:
| Group Not | Use front acarid average Quantity (individual/cm2) | After using 5 days, acarid is put down All quantity (individual/cm2) | After using 10 days, acarid is put down All quantity (individual/cm2) | Use 15 days acarids average Quantity (individual/cm2) | Suspend and use 10 days acarids to put down All quantity (individual/cm2) |
| 1 | 10.3 | 3.1 | 0.5 | 0.2 | 0.3 |
| 2 | 10.5 | 3.4 | 0.6 | 0.3 | 0.5 |
| 3 | 10.8 | 3.5 | 0.7 | 0.3 | 0.5 |
| 4 | 8.9 | 7.6 | 6.3 | 6.1 | 7.3 |
| 5 | 10.6 | 6.3 | 5.5 | 5.1 | 6.8 |
| 6 | 11.1 | 6.8 | 6.0 | 5.3 | 6.5 |
| 7 | 10.2 | 5.3 | 2.7 | 1.5 | 1.7 |
| 8 | 9.8 | 6.8 | 4.2 | 2.5 | 3.6 |
| 9 | 10.5 | 10.2 | 10.8 | 10.6 | 10.5 |
From above proof test data, 1-3 group (embodiment 1-3) have employed present composition raw material composition and joins
The acaricide worm Chinese medicine composition that side prepares, has synergistic function, and acaricide worm effect is notable, and speed is fast, and persistently has
Effect；4th group (comparative example 1) does not adds monarch drug Cortex Meliae, and compositions compatibility changes completely, and drug effect changes, acaricide worm poor effect；
5th group (comparative example 2) does not adds makes medicine Herb Gynostemmae Pentaphylli, and compositions compatibility changes, and loses synergistic function, acaricide worm between medical material
Effect is deteriorated；6th group (comparative example 3) does not use the raw material number of the present composition, and compatibility changes, and Herba Schizonepetae becomes monarch
Medicine, Cortex Meliae becomes ministerial drug, and the overall property of medicine of compositions prepared changes, and also loses synergistic function, remove between medical material
Acarid effect is deteriorated；The method that 7th group (comparative example 4) does not use the present invention to prepare compositions, has preferable acaricide equally
Worm effect, but the onset of drug effect slows, and the acaricide worm time is elongated；8th group is situation after existing acaricide worm cosmetics use,
Its acaricide worm effect is general, and speed is general, after cutting time-out use, and acarid secondary parasite the most again.
Claims (10)
1. the Chinese medicine composition for acaricide worm cosmetics containing Cortex Meliae, it is characterised in that described compositions be by
The raw material of following weight is prepared from: Herba Schizonepetae 10-18 part, Cortex Meliae 20-30 part, Flos Inulae 10-15 part, Flos Lonicerae
6-10 part, Herb Gynostemmae Pentaphylli 2-5 part, Fructus Tribuli 6-9 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is former by following weight
Material is prepared from: Herba Schizonepetae 12-15 part, Cortex Meliae 22-25 part, Flos Inulae 11-13 part, Flos Lonicerae 8-10 part, Herb Gynostemmae Pentaphylli 2-4
Part, Fructus Tribuli 7-9 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is former by following weight
Material is prepared from: Herba Schizonepetae 14 parts, Cortex Meliae 25 parts, Flos Inulae 12 parts, Flos Lonicerae 9 parts, Herb Gynostemmae Pentaphylli 3 parts, Fructus Tribuli 8 parts.
4. according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation side of described Chinese medicine composition
Method, its concrete preparation process is as follows:
(1), Herba Schizonepetae, Cortex Meliae, Flos Inulae, Flos Lonicerae, Herb Gynostemmae Pentaphylli, Fructus Tribuli are separately dried after pulverize, extract and concentrate,
Obtain Herba Schizonepetae extracting solution, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli extract, Fructus Tribuli extract；
(2), by the Herba Schizonepetae extracting solution of step 1 gained, Cortex Meliae extractive liquid, Flos Inulae extracting solution, Flos Lonicerae extractive solution, Herb Gynostemmae Pentaphylli
Extracting solution, Fructus Tribuli extract carry out maturation process respectively, carry out filtering, purifying to obtain each raw material essence, by each raw material after cooling
Essence mix homogeneously, and again carry out filtering, purifying, obtain mixing essence；
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtain containing Cortex Meliae in acaricide worm cosmetics
Drug composition.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Herba Schizonepetae
The curing temperature of extracting solution is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Melia azedarach L.
The curing temperature of skin extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, gold small cup
The curing temperature of flower extract is 60-65 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, gold silver
To spend the curing temperature of extracting solution be 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, strand
The curing temperature of blue extracting solution is 70-75 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, puncture
The curing temperature of Herba chenopodii extracting solution is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104450290A (en) * | 2013-09-16 | 2015-03-25 | 天津普范科技开发有限公司 | Laundry detergent for killing acarus |
| CN104946413A (en) * | 2015-05-26 | 2015-09-30 | 柳州市亿廷贸易有限责任公司 | Acarid-removal laundry detergent |
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2016
- 2016-06-08 CN CN201610400542.7A patent/CN105919870A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104450290A (en) * | 2013-09-16 | 2015-03-25 | 天津普范科技开发有限公司 | Laundry detergent for killing acarus |
| CN104946413A (en) * | 2015-05-26 | 2015-09-30 | 柳州市亿廷贸易有限责任公司 | Acarid-removal laundry detergent |
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| Title |
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