CN1058893C - Medicine for treating woman's dysmenorrhea and preparing process thereof - Google Patents

Medicine for treating woman's dysmenorrhea and preparing process thereof Download PDF

Info

Publication number
CN1058893C
CN1058893C CN97120289A CN97120289A CN1058893C CN 1058893 C CN1058893 C CN 1058893C CN 97120289 A CN97120289 A CN 97120289A CN 97120289 A CN97120289 A CN 97120289A CN 1058893 C CN1058893 C CN 1058893C
Authority
CN
China
Prior art keywords
radix
medicine
parts
treatment
dysmenorrhea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN97120289A
Other languages
Chinese (zh)
Other versions
CN1179327A (en
Inventor
王汝辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN97120289A priority Critical patent/CN1058893C/en
Publication of CN1179327A publication Critical patent/CN1179327A/en
Priority to PCT/CN1998/000264 priority patent/WO1999025368A1/en
Priority to AU10196/99A priority patent/AU1019699A/en
Application granted granted Critical
Publication of CN1058893C publication Critical patent/CN1058893C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/50Fumariaceae (Fumitory family), e.g. bleeding heart
    • A61K36/505Corydalis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention discloses a medicament for treating woman's dysmenorrhea, which uses faeces trogopterorum, red sage root, fructus, liquorice, nutgrass galingale rhizome, corydalis tuber, white peony root, sinomenium acutum, angelica, safflower, radix bupleuri and rock candy as raw materials which are encapsulated to wine or tincture after the working procedures of pulverization, sieving, soaking, centrifugal separation, filtration, clarifying, resoaking, centrifugal separation, filtration, clarification and mixing. The prescription and the preparation method of the medicament are peculiar, and the therapeutic effect is obvious.

Description

Medicine of treatment dysmenorrhes and preparation method thereof
The present invention relates to a kind of medicine for the treatment of dysmenorrhes, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.
Dysmenorrhea is common gynecological disease and frequently-occurring disease, the cause of disease is many, the pathogenesis complexity, repeatability is big, treat thorny, especially unmarried young woman and menarche the maiden general especially, before and after showing as gynecologic menstrual or passing through, the hypogastric region distending pain periodically takes place, cold type of pain, causalgia, twinge, dull pain, weigh down pain, angor, spasmic pain, tearing property pain, pain is extended down to the sacrum lower back, even relate to thigh and foot, often with General Symptoms: distending pain of the breast, the tripe door weighs down and expands, agitation uncomfortable in chest, sad irritability, the insomnia heart is frightened, headache and dizzy, nausea and vomiting, stomachache diarrhoea, fatigue and weakness, pale complexion, extremity are ice-cold, dripping cold sweat, collapse symptom such as faint.Have a strong impact on numerous women's working and learning and daily life, and caused psychology and anxiety in life and discomfort.Deliver numeral according to national woman month through physical constants cooperative groups (1980) investigation, China women is serious, and dysmenorrhea accounts for 13.55%, and moderate pain is through accounting for 38.81%.In " health care of women " book after the record menophania in 1 year primary dysmenorrhea account for to account in 75%, second year to account in 13%, the 3rd year and accounted for 4% in 5%, the 4th year.
China's population occupies first of the countries in the world, and the women accounts for population half, the height of body of women health level, the quality of body constitution, closely bound up with nationality prosperous happy family life, Ministry of Public Health bureau of drug administration has issued the clinical research guideline of treatment by Chinese herbs dysmenorrhea in June, 87, needs development to truly have the Chinese medicine of curative effect and new drug to be invested in clinical to primary disease.The doctor trained in Western medicine pain relieving of suiting the medicine to the illness at present is easy to generate drug resistance and the big situation of hormone therapy side effect, and Chinese medicine is subjected to generally paying attention to and the patient welcomes, great mass of data proves, no matter be that traditional disease executing of debating controlled, still the folk prescription proved recipe that emerges in large numbers recently, brought into play great role for the relieving dysmenorrhea symptom, but pain relieving is slow, administration time is long, and dosage form still falls behind, and the radical cure effect is not remarkable, in, doctor trained in Western medicine lacks specimen clinically and controls altogether, the active drug of radical cure dysmenorrhea, develop as early as possible and can be extensive use of for clinical, simple and effective treatment dysmenorrhea Chinese patent medicine is present problem extremely to be solved.
The object of the present invention is to provide a kind of curative effect height, specimen to control altogether, easy to use, cure mainly the TREATMENT OF DYSMENORRHOEA agent.
Another object of the present invention provides the preparation method that cures mainly the dysmenorrhea treatment agent.
Solution of the present invention is on the basis of secret prescription handed down in the family from generation to generation, at above-mentioned the deficiencies in the prior art, carries out exploratory development, according to the theory of blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, soothing liver-QI for relieving depression, dredging the meridian, and forms prescription.The inventor has consulted medical literature in a large amount of ancient times from motherland medicine treasure-house, with reference to modern pharmacology drug efficacy study achievement, collect numerous doctor families treatment experience, according to theory of Chinese medical science " stagnation of QI and blood may bring about pain, general rule not bitterly, qi depression to blood stasis, the capable then blood of gas is capable ".In conjunction with the pharmacodynamic study result of new Chinese medicine treatment dysmenorrhea, i.e. the dysmenorrhea no matter which kind of reason causes, all with hormone between dysequilibrium relevant, promptly PCF2a (prostaglandin) content raises in the dysmenorrhea patient blood plasma, then dysmenorrhea increases the weight of; PCF2a reduces, and then dysmenorrhea alleviates, and PCF2a is normal, and then dysmenorrhea disappears.Having determined prescription perfect according to a large amount of clinic trial cases again forms and effective dosage ranges.
Medicine of the present invention is made (consumption is a weight portion) by following component:
Oletum Trogopterori 10-25 part Radix Salviae Miltiorrhizae 6-20 part Fructus Aurantii 6-20 part
Radix Glycyrrhizae 5-20 part Rhizoma Cyperi 10-25 part Rhizoma Corydalis 10-25 part
Radix Paeoniae Alba 5-15 part Radix Stephaniae Tetrandrae 10-25 part Radix Angelicae Sinensis 5-15 part
Flos Carthami 3-12 part Radix Bupleuri 3-12 part
The composition of raw materials preferred weight ratio range of preparation medicine of the present invention is:
Oletum Trogopterori 12-20 part Radix Salviae Miltiorrhizae 8-15 part Fructus Aurantii 8-15 part
Radix Glycyrrhizae 7-15 part Rhizoma Cyperi 12-20 part Rhizoma Corydalis 12-20 part
Radix Paeoniae Alba 6-10 part Radix Stephaniae Tetrandrae 12-20 part Radix Angelicae Sinensis 6-10 part
Flos Carthami 4-10 part Radix Bupleuri 4-10 part
The optimum weight proportioning of medicine material of the present invention is:
10 parts of 10 parts of Fructus Aurantiis of 15 parts of Radix Salviae Miltiorrhizaes of Oletum Trogopterori
15 parts of 15 parts of Rhizoma Corydalis of 9 portions of Rhizoma Cyperis of Radix Glycyrrhizae
8 parts of 15 parts of Radix Angelicae Sinensis of 8 parts of Radixs Stephaniae Tetrandrae of the Radix Paeoniae Alba
6 parts of 6 parts of Radix Bupleuri of Flos Carthami
Can add crystal sugar 1-20 part in the medicine of the present invention, preferred 7-15 part, the best is 9 weight portions.
It can be conventional preparation process that above-mentioned each component is made medicine production method of the present invention, preparation process condition for medicine of the present invention does not have strict qualification, the professional in present technique field can implement fully, said components added in the pulverizer in described ratio pulverize, sieve and remove big slag, with Chinese liquor and medical material ratio is 1-12: 1 soaks, the concentration of Chinese liquor (also available edible ethanol or medical ethanol dilution offspring use) is 12-40%, be preferably 20-30%, steeping tank is used rustless steel, glass, ceramic material, then carry out centrifugalize, remove medicinal residues, refilter, separate slag and filtering residue reuse soaking in Chinese liquor except that clarifying behind the filtering residue, medicinal residues are removed in centrifugalize again, clarify behind the elimination filtering residue, two secondary clearing immersion add crystal sugar and mix, and medicated wine or tincture are made in encapsulation, also recyclable ethanol is made oral solutions, or concentrate drying is made electuary.Capsule, tablet.
Medicine of the present invention its most preferred dosage form at present is a medicated wine, because dysmenorrhea belongs to gynecological's pain disease, emergency case category, clinical at first is to need quickly alleviating pain, and the characteristics of medicated wine are exactly that pain relieving is fast, curative effect is high, is that other dosage form can't be compared, wine itself just has promoting blood circulation, resisting cold gas, row medicine gesture, control the wind and cold arthralgia pain, muscle arteries and veins contraction is anxious, the effect of thoracic obstruction trusted subordinate's cold type of pain, liquor preparation can improve dissolubility thus, relax the property of medicine, be easy to absorb and disperse.It can promote that the human intestines and stomach secretes, and facilitating digestion absorbs, and strengthens blood circulation, promotes tissue metabolism, increases the cell viability effect.Borrow capacity for liquor to drive the efficacy of a drug, operate among the collaterals of human blood vessels, between the yang blood and qi, reach the purpose that pain relieving is fast and cure.After no matter each disease dysmenorrhea patient took medicine, the sensation medicine was like the through rapidly hypogastric region of one warm current, and pain disappeared at once in 3-15 minute, and the heaviest patient also can accomplish not have pain, resumes work and study and daily life at once.If can before pain, take medicine, can make the patient not have pain and take place.General dysmenorrhea patient can cure in three cycles of taking medicine.
The first-selected medicated wine of the present invention takes into full account the received energy of women to wine, preparation has adopted low wine, wine has the smelly antiseptical effect of rectifying, and can correct and get rid of the Chinese medicine abnormal flavour, makes medicated wine become a kind of good to eat beverage, one glass of taste pure ends, the medicated wine that gives off a strong fragrance does not promptly have the worry of good medicine tastes bitter that ancients say, does not have the have an injection misery of fluid infusion of modern times yet, what bring to people is a kind of enjoyment of vintage wine good wine, so people are willing to accept.If be used to the alcohol user at ordinary times, take the comparable common people of medicated wine amount and slightly increase, but also GPRS sense of propriety, can not be undue, the uncomfortable people who drinks is when taking medicated wine, can progressively be increased to the amount that to take earlier from low dose, also can take after the cold boiled water dilution.
Medicated wine of the present invention can external to (the comprising ethanol) allergy sufferers of drinking, and medicated wine is dripped ear, can drip a side earlier, drip opposite side after 10 minutes again, or soak medicated wine with absorbent cotton and fill in auditory meatus or middle ear every interior, the lighter uses monaural, weight person uses ears, take out behind the alleviating pain, also available absorbent cotton soaks medicated wine and wipes or apply SHENQUE acupoint, Guanyuan acupoint, Zhongji acupoint, SANYINJIAO acupoint adds hot water bag above and accelerates drug effect, all can alleviating pain.Also medicated wine can be sprayed directly on external genital or sanitary towel surface, analgesic effect is all arranged.
Medicine of the present invention is oral administration and externally no matter, equal no side effects, safe and reliable, the effective percentage height, easy to use, in the treatment dysmenorrhea, to menoxenia, chronic pelvic inflammatory disease, hysteromyoma, endometriosis, pelvic congestion syndrome, uterine hypoplasia, infertility, the endocrine disturbance, common gynecological diseases such as chloasma also have certain curative effect, to pain after other pain, neuralgia, the wound, and some smooth muscle spasm pain, cancer pains etc. also can alleviate to a certain extent, have accomplished that a medicine controls more.
The first-selected medicated wine of medicine of the present invention can directly be contained in the container of little plastic bottle or vial and so on, is easy to keeping, and storage is for a long time never degenerated, and can carry, and is easy to use, 10-30 milliliter for oral administration, and suitable amount used externally gets final product.
Drug manufacture raw material of the present invention source is sufficient, and cost is low, technology is simple, equipment investment is few, economic benefit is high, is the good product of pharmaceuticals industry, is that the simple and effective Chinese patent medicine of dysmenorrhea is treated at present fabulous using.Can be extensive use of for clinical, not only can solve the hardship of numerous women's disease, and can improve the economic and social benefits, will play very big impetus gynopathic theory and clinical research.
Why medicine of the present invention produces, and outstanding effect as above is inseparable with the principles of formulating prescriptions of medicine of the present invention and prescription." General Treatise on the Cause and Symptoms of Diseases " record, " women's menstrual abdominalgia person, by the impairment caused by overstrain vim and vigour, so that body void, be subjected to air-cooled gas visitor in collaterals of the uterus ... fight with mutually with vim and vigour, so the order pain is also." illustrate that dysmenorrhes is relevant with air-cooled gas.And in the antidysmenorrheic thing in the past, adopt the method for treatment of blood circulation promoting and blood stasis dispelling mostly, and ignored the rule of treatment of expelling wind and removing dampness, so can not receive satisfied effect, medicine of the present invention on the material combination except that blood circulation promoting and blood stasis dispelling, select the Radix Stephaniae Tetrandrae expelling wind and removing dampness for use, drive away air-cooled gas, matching with the blood circulation promoting and blood stasis dispelling and the resolving depression of passing through, reach optimum efficiency, also is the distinctive feature that the present invention conceives.
Because medicine of the present invention has the uterine ligaments of expansion microvascular diameter, increase point of intersect of the capillary network, quicken blood flow rate, thereby improve the uterus microcirculation function, alleviate the spastic contraction of uterine smooth muscle, medicine of the present invention reduces the effect of menses Prostaglandin F2a content, so can be used for dissimilar clinically dysmenorrheas.
The treatment dysmenorrhea effect of medicine of the present invention is remarkable, pain relieving in 3-15 minute, and three cycles cure, and are that other treatment dysmenorrhea medicine institute is inaccessible.
Embodiment
Composition of raw materials:
Oletum Trogopterori 15 gram Radix Salviae Miltiorrhizaes 10 gram Fructus Aurantiis 10 grams
Radix Glycyrrhizae 9 gram Rhizoma Cyperis 15 gram Rhizoma Corydalis 15 grams
The Radix Paeoniae Alba 8 gram Radixs Stephaniae Tetrandrae 15 gram Radix Angelicae Sinensis 8 grams
Flos Carthami 6 gram Radix Bupleuri 6 gram crystal sugar 9 grams
Method for making:
The raw material of above-mentioned component is except that crystal sugar, go in the pulverizer in proportion to pulverize, sieve and remove big slag, soak with 12: 1 ratio with Chinese liquor and medical material, the concentration of Chinese liquor is 30%, soaks after 7 days, carry out centrifugalize, remove medicinal residues, refilter, make it clarification except that behind the filtering residue, centrifugalize medicinal residues and filtration medicinal residues reuse soaking in Chinese liquor, cross powder with soaking in Chinese liquor and be advisable, soaked 7 days, medicinal residues are removed in centrifugalize again, behind the elimination filtering residue, make it clarification, two secondary clearing immersion add crystal sugar and mix, and medicated wine is made in encapsulation.

Claims (7)

1. medicine for the treatment of dysmenorrhes is characterized in that it is the medicament of being made by the following weight proportion raw material:
Oletum Trogopterori 10-25 part Radix Salviae Miltiorrhizae 6-20 part Fructus Aurantii 6-20 part
Radix Glycyrrhizae 5-20 part Rhizoma Cyperi 10-25 part Rhizoma Corydalis 10-25 part
Radix Paeoniae Alba 5-15 part Radix Stephaniae Tetrandrae 10-25 part Radix Angelicae Sinensis 5-15 part
Flos Carthami 3-12 part Radix Bupleuri 3-12 part.
2. the medicine of treatment dysmenorrhes according to claim 1, wherein the weight proportion of each raw material is:
Oletum Trogopterori 12-20 part Radix Salviae Miltiorrhizae 8-15 part Fructus Aurantii 8-15 part
Radix Glycyrrhizae 7-15 part Rhizoma Cyperi 12-20 part Rhizoma Corydalis 12-20 part
Radix Paeoniae Alba 6-10 part Radix Stephaniae Tetrandrae 12-20 part Radix Angelicae Sinensis 6-10 part
Flos Carthami 4-10 part Radix Bupleuri 4-10 part.
3. the medicine of treatment dysmenorrhes according to claim 1, wherein the weight proportion of each raw material is:
10 parts of 10 parts of Fructus Aurantiis of 15 parts of Radix Salviae Miltiorrhizaes of Oletum Trogopterori
15 parts of 15 parts of Rhizoma Corydalis of 9 portions of Rhizoma Cyperis of Radix Glycyrrhizae
8 parts of 15 parts of Radix Angelicae Sinensis of 8 parts of Radixs Stephaniae Tetrandrae of the Radix Paeoniae Alba
6 parts of 6 parts of Radix Bupleuri of Flos Carthami.
4. according to the medicine of claim 1 or 2 or 3 described treatment dysmenorrhes, it is characterized in that also containing in the said medicament crystal sugar of 1-20 weight portion.
5. the medicine of treatment dysmenorrhes according to claim 4 is characterized in that said medicament is medicated wine or tincture.
6. the preparation method of the medicine of treatment dysmenorrhes according to claim 5, it is characterized in that getting earlier Oletum Trogopterori, Radix Salviae Miltiorrhizae, Fructus Aurantii, Radix Glycyrrhizae, Rhizoma Cyperi, Rhizoma Corydalis, the Radix Paeoniae Alba, Radix Stephaniae Tetrandrae, Radix Angelicae Sinensis, Flos Carthami, Radix Bupleuri, through pulverizing, sieving and remove big slag, soak with Chinese liquor, then carry out the centrifugalize slagging-off, refilter and remove filtering residue, separate slag and cross filtering residue reuse soaking in Chinese liquor, then carry out the centrifugalize slagging-off, refilter slagging-off, two secondary clearing immersion add the crystal sugar mix homogeneously, through encapsulation medicated wine or tincture.
7. according to the method for claim 6, wherein soak with Chinese liquor with edible ethanol or medical ethanol dilution offspring, diluted concentration is 12-40%, and ethanol is 1-12 with the leaching ratio of Chinese crude drug: 1.
CN97120289A 1997-11-13 1997-11-13 Medicine for treating woman's dysmenorrhea and preparing process thereof Expired - Fee Related CN1058893C (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN97120289A CN1058893C (en) 1997-11-13 1997-11-13 Medicine for treating woman's dysmenorrhea and preparing process thereof
PCT/CN1998/000264 WO1999025368A1 (en) 1997-11-13 1998-11-06 A medicine for treating algomenorrhea and the method of preparation thereof
AU10196/99A AU1019699A (en) 1997-11-13 1998-11-06 A medicine for treating algomenorrhea and the method of preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN97120289A CN1058893C (en) 1997-11-13 1997-11-13 Medicine for treating woman's dysmenorrhea and preparing process thereof

Publications (2)

Publication Number Publication Date
CN1179327A CN1179327A (en) 1998-04-22
CN1058893C true CN1058893C (en) 2000-11-29

Family

ID=5175874

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97120289A Expired - Fee Related CN1058893C (en) 1997-11-13 1997-11-13 Medicine for treating woman's dysmenorrhea and preparing process thereof

Country Status (3)

Country Link
CN (1) CN1058893C (en)
AU (1) AU1019699A (en)
WO (1) WO1999025368A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100335101C (en) * 2004-08-20 2007-09-05 黄小兰 Dysmenorrhea treating medicine
TWI298259B (en) * 2004-10-08 2008-07-01 Tzu Chi Buddhist General Hospital Pharmaceutical composition for inhibiting/treating brain cancer
US7713555B2 (en) * 2007-07-19 2010-05-11 Cheng Jin Lubricant additive to enhance staying power of male erectile function
CN101129971B (en) * 2007-09-25 2010-11-24 徐有章 Traditional Chinese medicine composition for treating women's menorrhalgia and menoxenia, and method of preparing the same
CN102641361B (en) * 2012-02-21 2014-02-26 常熟华港制药有限公司 Chinese herb preparation for treating abnormal menstruation
CN102614343A (en) * 2012-05-01 2012-08-01 马守云 Medicament for treating dysmenorrhea
CN105999205A (en) * 2016-08-11 2016-10-12 朱其臣 Traditional Chinese medicine for treating cancer pain
CN109700910A (en) * 2017-10-25 2019-05-03 杜学双 Gynaecological disease formula
CN114098032A (en) * 2021-11-24 2022-03-01 王嘉骏 Red crab soup for dietary therapy for treating dysmenorrhea
CN115120661B (en) * 2022-08-15 2024-04-02 冯玲 A topical Chinese medicinal composition for treating dysmenorrhea, and its preparation method
CN116211983B (en) * 2023-01-17 2024-05-07 昆明理工大学 Gastrodia elata prescription medicine for treating primary dysmenorrhea and application thereof

Also Published As

Publication number Publication date
CN1179327A (en) 1998-04-22
AU1019699A (en) 1999-06-07
WO1999025368A1 (en) 1999-05-27

Similar Documents

Publication Publication Date Title
CN102293874B (en) Multifunctional medicinal pillow and preparation method thereof
CN100506251C (en) Chinese medicine preparation for treating mastoproliferation and preparation method thereof
CN102106974B (en) Oral liquid for healing hemiplegia
CN103386088B (en) Chinese medicine composition for treating insomnia
CN1058893C (en) Medicine for treating woman's dysmenorrhea and preparing process thereof
CN104435692A (en) Prescription for treating nerve headache and preparation method thereof
CN102058715B (en) Chinese medicine preparation for treating chronic prostatitis and preparation method thereof
CN104547036B (en) A kind of medicinal liquor for treating rheumatism
CN102085299B (en) Chinese patent medicine for treating prostatitis and preparation method thereof
CN102362983A (en) Chinese medicinal composition for treating dizziness
CN101972446B (en) Medicament for treating coronary disease and preparation method thereof
CN101269157B (en) Method for preparing wine for warming meridian, removing paralysism, releasing tendon, activating collaterals to relieve pain
CN101953989A (en) Electromagnetic wave vision rehabilitation instrument and Chinese medicinal composition
CN102920807A (en) Herb tea for lowering blood pressure
CN102949507B (en) Traditional Chinese medicine lotion for treating lumbocrural pain and preparation method thereof
CN1116883C (en) Medicated wine for treating rheumatism and pain bones and muscles and its preparation
CN112043805A (en) Preparation method of external-use spleen and stomach strengthening and digestion promoting plaster
CN104940613A (en) Traditional Chinese medicine pills for treating vestibular neuritis and preparation method
CN104758652A (en) Traditional Chinese medicine composition for treating dizziness
CN100546629C (en) The Chinese medicine preparation and the preparation method of treatment liver-Yang sthenia type climacteric syndrome
CN103356962B (en) Traditional Chinese medicine composition for treating climacteric syndrome
CN103736027A (en) Traditional Chinese medicine composition for treating insomnia
CN110464803A (en) A kind of Chinese medicine composition and preparation method thereof for reducing blood pressure
CN100998770A (en) Hypertensor plaster with tranquilizing function
CN101112604A (en) Medicine for treating glaucoma and method for preparing the same

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20001129

Termination date: 20121113