CN105878275A

CN105878275A - Edible montmorillonite nanogel

Info

Publication number: CN105878275A
Application number: CN201510011560.1A
Authority: CN
Inventors: 许铨先; 王志强
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-01-08
Filing date: 2015-01-08
Publication date: 2016-08-24

Abstract

The invention discloses an edible montmorillonite nanogel. The edible montmorillonite nanogel is characterized by consisting of montmorillonite and water, and the edible montmorillonite nanogel is represented as a semi-transparent emulsion. The finished product (the edible montmorillonite nanogel) is processed from medicinal montmorillonite powder as a raw material by pulping, swelling, dispersing at a high speed and modifying through such pure physical methods as ultrahigh pressure micro-jet nano-dispersion and the like, and the grain size of the montmorillonite dispersed in the water is less than 100nm, so that the finished gel product is obtained. The finished product, after entering a human digestive tract, can be attached to gastrointestinal mucosa tissues, so as to effectively repair damaged gastrointestinal mucosa and to selectively adsorb viruses, germs and various toxins in intestines and stomach. The finished product, instead of being absorbed in human body, is finally discharged out of the human body along with feces, so that special detoxifying and toxin eliminating functions are completed.

Description

A kind of edible montmorillonite nano gel

Technical field

The present invention relates to a kind of edible montmorillonite nano gel.

Background technology

Montmorillonite (also referred to as montmorillonite, montmorillonite) is a kind of layered hydrous aluminium silicate mineral, has lamellar structure and heterogeneity electric charge The toxin of the virus in digestive tract, pathogenic bacteria and generation thereof, gas etc. are had extremely strong fixing, inhibitory action so that it is lose pathogenic effects by distribution； In addition alimentary canal mucous membrane is also had the strongest covering protection ability, repairs, improve the Mucosa Barrier defense function to attack factor, there is balance just Often flora and local analgesic effect.

Montmorillonite has natural layer structure, and interlayer contains exchangeable cations, and each crystal layer is pressed from both sides one layer of alumina octahedral group by two-layer silicon-oxy tetrahedron Become, belong to 2: 1 types, form the structure of similar " sandwich ".Between montmorillonite each structure sheaf 1-2nm, it it is a kind of natural nano material.Receive The montmorillonite of riceization is due to nanometer size effect, and the performances such as its specific surface area is greatly promoted, removing toxic substances also have more common montmorillonite to have significantly to promote.But Have motive power between layers due to montmorillonite, nature montmorillonite granule is bigger, the most common physics, chemical processes product Also it is only capable of reaching micron level, does not reaches the requirement of nano material, it is impossible to fully realize the special efficacy of montmorillonite.

Patent ZL 200610042359 " preparation method of nanometer Montmorillonitum " discloses the production method of a kind of nanometer technology, and the method is for realizing covering The nanorize of de-stone, have employed carbamide, poly-pears acid esters intercalator, after employing, and upper use in the industry preferably of nanorize product, and be not suitable for using In food service industry.

There is the most above-mentioned problem in patent ZL 02115591.7 " preparation method of nanometer Montmorillonitum ".Meanwhile, sample average particle diameter described in patent 380nm, does not reaches the requirement of nano material, and stricti jurise does not claims nano material.

Patent ZL 200510091244.6 " montmorillonite is as the composition protecting gastrointestinal mucosa before drinking " discloses the montmorillonite guarantor for gastrointestinal mucosa Protect mechanism, but only describe the pharmaceutical characteristic of common montmorillonite, be not set out any processing method, and it was verified that the most all of illiteracy takes off Stone is suitable for cooking food, and the montmorillonite drug effect of the conventional particle size described in patent inconspicuous.

Summary of the invention

Edible montmorillonite nano gel of the present invention, is characterized in that montmorillonite forms with water, and a kind of outward appearance processed through special process is There is the translucent emulsion form of certain viscosity, after this product enters human body alimentary canal, can be attached in gastrointestinal mucosa tissue, to the intestines and stomach damaged Mucosa is effectively repaired, and optionally adsorbs the virus in the intestines and stomach, pathogenic bacteria and various toxin.This product will not be inhaled in human body Receive, excrete with feces the most at last, complete its distinctive removing toxic substances, functions of expelling toxin.

Inventing described montmorillonite nano gel and use pharmaceutical grade montmorillonite powder powder body for edible rank, primary raw material, smectite content is not less than 95%, Dioxide-containing silica 55.0-65.0%, aluminium sesquioxide content 12.0%-25.0%, cation exchange capacity (CEC) be more than 100mmol/g, color canescence or Person is slightly yellow.Although use montmorillonite powder can improve the production cost of product as the raw materials for production of montmorillonite nano gel, but easily controllable production During product quality, simultaneously without the discharge of any waste water, production site is required relatively low, it is simple to the popularization of industrialization.

Owing to montmorillonite has chance water " disintegrate ", the most expanded swelling characteristic, this invention is first by montmorillonite powder raw material and certain proportion pure water Mixing, control solids in pulp amount 10-30%, employing normal agitation machine, stirring at low speed 0.5-2 hour, the most expanded swelling 24 hours, it is therefore an objective to Use more natural mode to make montmorillonite raw material be separated into thinner granule in water, both ensured the effect of follow-up nanorize technique, and also saved follow-up Production cost.Root it was found that the montmorillonite of fine particulate in water after 24 hours expanded swelling, grain diameter is respectively less than 10 microns, Major part grain diameter less than 2 microns.

The most expanded swelling montmorillonite serosity, owing to concentration is bigger, in addition it is also necessary to supplement certain proportion pure water, slip is diluted to solid content 1-5%, Using high speed dispersor stirring 10-60min to be attenuated by montmorillonite granule further, mixing speed 3000-8000 per minute turns, and then uses industry to lead to By ZNN-D6 type six speed rotating cylinder viscometer tested viscosity.Owing to China's each place of production montmorillonite performance difference is relatively big, different montmorillonite powder raw material production Phosphoric acid also has relatively big difference, and according to the needs of subsequent technique, 600 turns of viscosity most preferably should be between 5-15mPa.s.

If phosphoric acid is less than 5mPa.s, then by adding the edible soda of montmorillonite amount 0.5%-3%, controls slurry temperature scope 50-70 DEG C, enter One step uses high speed dispersor stirring, and mixing speed 2000-5000 per minute turns, it is achieved the increase of phosphoric acid；If higher than 15mPa.s, passing through Supplement the method that pure water reduces the solid content of slip, it is achieved the reduction of phosphoric acid.

Subsequently, the qualified slip of each side such as viscosity, injects and carries out high intensity cutting in super-voltage micro jet nano-dispersed machine and delaminate, work Stress control is between 150-300Mpa.Test proves, once dispersion is extremely difficult to effect, therefore needs to select by organizing equipment, by series connection more Mode, make montmorillonite grain diameter 90% degree in serosity less than 100nm, form that to have certain viscosity outward appearance be the most non-setting translucent illiteracy De-stone nanogel.

Super-voltage micro jet nano-dispersed machine can make the material of suspension state under supertension effect, flows through the height with special internal structure at a high speed , there are a series of changes such as physics, chemistry, structural property, be finally reached the effect of nanorize in pressure homogenizing chamber.It is mainly used in biology, medicine, food The industry such as product, chemical industry.Equipment is mainly made up of high pressure homogenize chamber and booster body.High pressure homogenize chamber is the core component of equipment, permissible from principle It is divided into collision type and Y correlation type.Collision type can be divided into again cavitation pitting nozzle type and collision valve body type, cavitation pitting nozzle type directly refer to high pressure cutting and Cavitation erosion nozzle arrangements in spacecraft propulsion technology, but due under the effect of supertension, the valve core meeting that material solution is the most small through aperture Producing the speed of several times of velocities of sound, and with valve core internal structure, fierce friction and collision occur, therefore its service life is shorter, and it is micro-to be attended by metal Grain residual fall；Collision valve body type, by collision valve and the introducing of collision ring structure, reduces concentrated wear, extends the service life in homogenizing chamber.But Due in its cardinal principle or by the material in solution and high rigidity metal (such as tungsten alloy) structural collision, thus the abrasion of metal particle residual fall Problem the most thoroughly solves.The basic difference of Y correlation type is that it applies the principle to jet.Utilize distinctive Y-shaped structure, make high-pressure solution The material of high speed motion from colliding, substantially increases the service life of cavity, and solve metal particle residual fall problem.

The mineralogical compositions such as the montmorillonite raw material that montmorillonite nano gel uses inevitable association of meeting during mineral formation is quartzy, although passing through Major part quartz can be proposed to go by the method for various purifications, but still has a small amount of quartz existence, and these quartz are mixed in montmorillonite formation serosity, Carry out nanorize etc. a series of during can be formed and there is high pressure jer cutting effect " water cutter ", if only considering nanorize effect and being not added with district Point employing collision type homogenizing chamber produce time, residual fall inert metal granule be likely to occur gathering or formed larger particle, affect equipment life and illiteracy De-stone nanogel quality, product likely causes acute or chronic inflammatory reaction in entering human body；Y correlation type, due to internal structure reason, works as thing When the concentration of material and viscosity are bigger, relatively collision type is more easy to block, and therefore strictly to control concentration and the viscosity of product pan feeding.

The montmorillonite gelling processed through nanorize is sent into and is carried out liquid filled bottle with the can packing machine of bactericidal unit and can form product.

Accompanying drawing explanation

Fig. 1 montmorillonite nano gel production technological process

Fig. 2 montmorillonite raw material X diffraction analysis

Fig. 3 montmorillonite raw material mineral component analysis

Fig. 4 montmorillonite raw material CEC (cation exchange capacity) index test

Fig. 5 montmorillonite nano gel products size distribution curve

Detailed description of the invention

Below in conjunction with example, the invention will be further elaborated:

1) choosing pharmaceutical grade montmorillonite powder powder body is raw material, and smectite content is not less than 95%, dioxide-containing silica 55.0-65.0%, and aluminium sesquioxide contains Amount 12.0%-25.0%, cation exchange capacity (CEC) is more than 100mmol/g, color canescence or slightly yellow.

2) being mixed with certain proportion pure water by montmorillonite raw material, control solids in pulp amount 10-30%, use normal agitation machine, stirring at low speed 0.5-2 is little Time, the most expanded swelling 24 hours.

3) slip supplements certain proportion pure water, controls solids in pulp amount 1-5%, uses high speed dispersor stirring 10-60min, and mixing speed is per minute 3000-8000 turns.

4) use industry universal ZNN-D6 type six speed rotating cylinder viscometer testing procedure 3 600 turns of viscosity of slip, most preferably should between 5-15mPa.s, If less than 5mPa.s, accounted for the edible soda of montmorillonite amount 0.5%-3% by interpolation, control slurry temperature scope 50-70 DEG C, use further at a high speed Dispersion machine stirring 10-30min, mixing speed 2000-5000 per minute turn, it is achieved the increase of phosphoric acid；If higher than 15mPa.s, by supplementing Pure water reduces the method for the solid content of slip, it is achieved the reduction of phosphoric acid.

5) meeting and carry out high intensity cutting in the slip injection Y correlation type super-voltage micro jet nano-dispersed machine of viscosity requirement and delaminate, operating pressure controls Between 150-300Mpa, according to material practical situation, can be with multi-pass operation, until the montmorillonite granule 90% in product is less than 100nm, Now product appearance is the most non-setting translucent gel.

6) treated montmorillonite nano gel is sent into the can packing machine with bactericidal unit and is carried out liquid filled bottle and can form product.

The present invention is further illustrated below by embodiment 1.

Embodiment 1

1) the montmorillonite powder powder body choosing the production of Zhejiang enterprise is raw material, raw material smectite content 95.3%, quartz 4.7%, dioxide-containing silica 59.40%, aluminium sesquioxide content 18.03%, cation exchange capacity (CEC) is more than 104.34mmol/g, and colours white, such as Fig. 2,3,4.

2) this montmorillonite raw material is mixed with certain proportion pure water, control solids in pulp amount 15%, employing normal agitation machine, stirring at low speed 1 hour, The most expanded swelling 24 hours.

3) slip supplements certain proportion pure water, controls solids in pulp amount 3%, uses high speed dispersor stirring 30min, and it is 5000 that revolutions per minute controls Turn.

4) after tested, 600 turns of viscosity of serosity are 3mPa.s, less than 5mPa.s.Through test of many times, add the edible soda of montmorillonite amount 2%, control Slurry temperature processed 70 DEG C, uses further high speed dispersor 3000 rotating speeds stirring 15min per minute, phosphoric acid increase to 7Pa.s, meet and receive Rice processes feed needs.

5) being injected by slip and carry out 3 high intensity cuttings in Y correlation type super-voltage micro jet nano-dispersed machine and delaminate, operating pressure is set as 180Mpa, montmorillonite serosity outward appearance now is the most non-setting translucent gel.After tested, product granularity is all in below 54nm, average particle Degree 7 to 15nm, such as Fig. 5.

6) montmorillonite nano gel is sent into the can packing machine with bactericidal unit and carry out liquid filled bottle.

Claims

1. an edible montmorillonite nano gel, is characterized in that product is made up of with water montmorillonite, and outward appearance is to have the translucent emulsion form of certain viscosity.

Product the most according to claim 1, with pharmaceutical grade montmorillonite powder powder body as raw material, raw material smectite content is not less than 95%, silicon dioxide Content 55.0-65.0%, aluminium sesquioxide content 12.0%-25.0%, cation exchange capacity (CEC) is more than 100mmol/g, color canescence or slightly yellow.

Product the most according to claim 1, mixes montmorillonite raw material with certain proportion pure water, controls solids in pulp amount 10-30%, uses general Logical blender, stirring at low speed 0.5-2 hour, the most expanded swelling 24 hours.

Slip the most according to claim 3, supplements certain proportion pure water, controls solids in pulp amount 1-5%, uses high speed dispersor stirring 10-60min, mixing speed 3000-8000 per minute turn.

Slip the most according to claim 4 uses industry universal ZNN-D6 type six speed rotating cylinder viscometer tested viscosity, and its 600 turns of viscosity should be Between 5-15mPa.s, if accounted for the edible soda of montmorillonite amount 0.5%-3% by interpolation less than 5mPa.s, control slurry temperature scope 50-70 DEG C, High speed dispersor stirring 10-30min, mixing speed 2000-5000 per minute is used to turn further, it is achieved the increase of phosphoric acid；Higher than 15mPa.s The method being reduced the solid content of slip by supplementary pure water, it is achieved the reduction of phosphoric acid.

The most according to claim 5, the slip of viscosity 5-15mPa.s, inject and carry out high intensity cutting in super-voltage micro jet nano-dispersed machine and delaminate, Operating pressure controls between 150-300Mpa, according to material practical situation, can with multi-pass operation, until the montmorillonite granule 90% in product with Upper less than 100nm, now product appearance is the most non-setting translucent gel.

High pressure microjet nano-dispersed machine homogenizing cavity configuration the most according to claim 6 should use Y correlation type.