CN105853783A - Traditional Chinese medicinal composition for treating rosacea - Google Patents

Traditional Chinese medicinal composition for treating rosacea Download PDF

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CN105853783A
CN105853783A CN201610222918.XA CN201610222918A CN105853783A CN 105853783 A CN105853783 A CN 105853783A CN 201610222918 A CN201610222918 A CN 201610222918A CN 105853783 A CN105853783 A CN 105853783A
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parts
radix
herba
chinese medicine
rhizoma
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刘昌红
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    • A61K36/18—Magnoliophyta (angiosperms)
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating rosacea. The traditional Chinese medicinal composition comprises, by weight, 10-30 parts of Crotalaria ferruginea Grah. ex Benth., 5-25 parts of Hedyotis diffusa, 5-20 parts of Flos Campsis, 5-25 parts of Ludwigia octovalvis, 5-25 parts of Folium Isatidis, 5-25 parts of Cogongrass rhizome, 5-20 parts of Radix Glehniae, 5-25 parts of Cottonrose Hibiscus, 5-25 parts of Pyrrosia lingua, 5-25 parts of Solidago decurrens, 5-20 parts of Spina Gleditsiae, 5-25 parts of Lithospermum erythrorhizon, 5-25 parts of radix scrophulariae, 5-25 parts of Herba Violae, 5-20 parts of sophora flavescens, 5-25 parts of Amur Corktree Bark, 5-25 parts of gypsum rubrum, 5-25 parts of honeysuckle flower, 5-20 parts of Rhizoma Anemarrhenae, 5-25 parts of Rhizoma Polygoni Cuspidati, 5-20 parts of dahurian angelica root, 5-25 parts of Piper betle L., 5-25 parts of Radix Ranunculi Ternati and 5-15 parts of licorice root. The traditional Chinese medicinal composition has the efficacy of clearing lung heat and eliminating heat, tonifying stomach and promoting fluid, clearing heat and draining dampness, activating blood circulation and dissipating blood stasis, expelling pus and killing parasites, and dispelling wind and relieving itching, has a substantial treatment effect on rosacea, and has reliable effects.

Description

A kind for the treatment of Rosacea Chinese medicine composition
Technical field
The present invention relates to the pharmaceutical product not determining structure of a kind of traditional herbal medicines, a kind of Chinese medicine composition treating rosacea.
Background technology
Rosacea mostly occurs in nose accuracy and nose both sides, and with erubescence, pimple, pustule, even nose increases the thickening a kind of dermatosis being characterized, primary disease Chang Bingfa seborrheic dermatitis.There is red little pimple, papulovesicle and pustule in nose in early days, nose capillary injection is serious, obvious dendritic blood capillary branch seen from naked eyes, there is pachydermatosis in late period, the tuberosity that differs in size and rough hypertrophy occur on nose, nose hypertrophy is uncomfortable, has a strong impact on that the image of patient is attractive in appearance and mental health.Mainly dividing currently for the treatment means of rosacea and have two classes, medicine for external use controls portion and interior application treatment；The anti-inflammation and sterilization medicines such as medicine for external use many employings lincomycin, Fusidic Acid Cream, Metrogel, the oral medicines such as innerlich anwenden many employings tinidazole, tetracycline, but said medicine contains antibiotic and some other harmful chemicals composition, numerous crowds should not be used, and there is unsatisfactory curative effect, treatment cycle is long, even increases the weight of the state of an illness to patient, causes more painful deficiency.
Motherland's medical science is thought that rosacea is many and is steamed by lung stomach accumulated heat, or because pungent delicious food thickness of being addicted to drink is greasy, damp and hot long steaming does not dissipates, and is retarded by silt and causes in face.
According to theory of Chinese medical science, for the pathogeny of rosacea, use lung heat clearing to expel the heat-evil, reinforcing stomach reg fluid, clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, evacuation of pus parasite killing, the method for the treatment of of dispelling wind for relieving itching, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome treatment rosacea in prior art to there is unsatisfactory curative effect, treatment cycle is long, even increasing the weight of the state of an illness to patient, cause more painful deficiency, the present invention provides a kind of and prepares simplicity, low cost, evident in efficacy, the Chinese medicine composition for the treatment of rosacea that has no side effect.
nullThe technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating rosacea，It is characterized in that: its raw material of Chinese medicine and weight be: Herba Crotalariae Ferrugineae 10-30 part、Herba Hedyotidis Diffusae 5-25 part、Flos Campsis 5-20 part、Ludwigia octovalvis (Jacq.) Raven 5-25 part、Folium Isatidis 5-25 part、Rhizoma Imperatae 5-25 part、Radix Glehniae 5-20 part、Hibisci Mutabilis 5-25 part、Folium Pyrrosiae 5-25 part、Herba Solidaginis 5-25 part、Spina Gleditsiae 5-20 part、Radix Arnebiae (Radix Lithospermi) 5-25 part、Radix Scrophulariae 5-25 part、Herba Violae 5-25 part、Radix Sophorae Flavescentis 5-20 part、Cortex Phellodendri 5-25 part、Mirabilitum crystallina 5-25 part、Flos Lonicerae 5-25 part、Rhizoma Anemarrhenae 5-20 part、Rhizoma Polygoni Cuspidati 5-25 part、Radix Angelicae Dahuricae 5-20 part、Beans leaf 5-25 part、Radix Ranunculi Ternati 5-25 part、Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating rosacea, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Crotalariae Ferrugineae 20 parts, Herba Hedyotidis Diffusae 15 parts, Flos Campsis 10 parts, Ludwigia octovalvis (Jacq.) Raven 15 parts, Folium Isatidis 15 parts, Rhizoma Imperatae 15 parts, Radix Glehniae 10 parts, Hibisci Mutabilis 15 parts, Folium Pyrrosiae 15 parts, Herba Solidaginis 15 parts, Spina Gleditsiae 10 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Scrophulariae 15 parts, Herba Violae 15 parts, Radix Sophorae Flavescentis 10 parts, Cortex Phellodendri 15 parts, Mirabilitum crystallina 15 parts, Flos Lonicerae 15 parts, the Rhizoma Anemarrhenae 10 parts, Rhizoma Polygoni Cuspidati 15 parts, the Radix Angelicae Dahuricae 10 parts, 15 parts of beans leaf, Radix Ranunculi Ternati 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Herba Crotalariae Ferrugineae has nourishing the kidney and liver、Relieving cough and asthma、Effect of eliminating damp, detoxifying；Herba Hedyotidis Diffusae has effect of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain；Flos Campsis has effect of clearing away heat and cooling blood, blood stasis-eliminating and stagnation-dissipating, dispelling wind for relieving itching；Ludwigia octovalvis (Jacq.) Raven has effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling；Folium Isatidis has effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing；Rhizoma Imperatae has effect of cooling blood for hemostasis, clearing away heat and promoting diuresis；Radix Glehniae has effect of nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid；Hibisci Mutabilis has effect of heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis；Effect that Folium Pyrrosiae has relieving stranguria by diuresis, lung heat clearing expels the heat-evil；Herba Solidaginis has wind and heat dispersing, effect of subduing swelling and detoxicating；Spina Gleditsiae has detumescence poison holding, effect of evacuation of pus parasite killing；Radix Arnebiae (Radix Lithospermi) has clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, effect of removing toxic substances rash；Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication；Herba Violae has heat-clearing and toxic substances removing, effect of removing heat from blood detumescence；Radix Sophorae Flavescentis has effect of heat clearing and damp drying, wind dispelling insecticide；Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging except steaming, effect of detoxification sore treatment；Mirabilitum crystallina has resolving heat and reducing pathogenic fire, effect of profit key detumescence；Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating；The Rhizoma Anemarrhenae has clearing away heat-fire, effect moisturized of promoting the production of body fluid；Rhizoma Polygoni Cuspidati has effect of promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the collateral, clearing away heat-damp and promoting diuresis, removing toxic substances, relieving cough and resolving phlegm；The Radix Angelicae Dahuricae has relieving exterior syndrome and dispelling cold, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, effect of detumescence and apocenosis；Beans leaf has effect that expelling wind and cold, promoting the circulation of QI and reducing phlegm, removing toxic substances and promoting subsidence of swelling, dry temperature are antipruritic；Radix Ranunculi Ternati has effect of mass dissipating and swelling eliminating；Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component through dialectical compatibility, helps using mutually assistant, play altogether lung heat clearing expel the heat-evil, reinforcing stomach reg fluid, clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, evacuation of pus parasite killing, effect of dispelling wind for relieving itching, the treatment to rosacea reaches treating both the principal and secondary aspects of a disease.
The component of the present composition all uses natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, low cost.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug use the use that is decocted in water for oral dose.Verifying by clinic application, it is evident in efficacy reliably, mild in medicine property and, do not occur that toxic and side effects, effective percentage reach 96%, cure rate 74.6%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
A kind of Chinese medicine composition treating rosacea, its raw material of Chinese medicine and weight proportion be: Herba Crotalariae Ferrugineae 20g, Herba Hedyotidis Diffusae 15g, Flos Campsis 10g, Ludwigia octovalvis (Jacq.) Raven 15g, Folium Isatidis 15g, Rhizoma Imperatae 15g, Radix Glehniae 10g, Hibisci Mutabilis 15g, Folium Pyrrosiae 15g, Herba Solidaginis 15g, Spina Gleditsiae 10g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Scrophulariae 15g, Herba Violae 15g, Radix Sophorae Flavescentis 10g, Cortex Phellodendri 15g, Mirabilitum crystallina 15g, Flos Lonicerae 15g, Rhizoma Anemarrhenae 10g, Rhizoma Polygoni Cuspidati 15g, Radix Angelicae Dahuricae 10g, beans leaf 15g, Radix Ranunculi Ternati 15g, Radix Glycyrrhizae 10g.
Embodiment 2
A kind of Chinese medicine composition treating rosacea, its raw material of Chinese medicine and weight proportion be: Herba Crotalariae Ferrugineae 15g, Herba Hedyotidis Diffusae 25g, Flos Campsis 12g, Ludwigia octovalvis (Jacq.) Raven 20g, Folium Isatidis 5g, Rhizoma Imperatae 25g, Radix Glehniae 5g, Hibisci Mutabilis 20g, Folium Pyrrosiae 10g, Herba Solidaginis 25g, Spina Gleditsiae 5g, Radix Arnebiae (Radix Lithospermi) 20g, Radix Scrophulariae 10g, Herba Violae 25g, Radix Sophorae Flavescentis 5g, Cortex Phellodendri 20g, Mirabilitum crystallina 10g, Flos Lonicerae 25g, Rhizoma Anemarrhenae 5g, Rhizoma Polygoni Cuspidati 20g, Radix Angelicae Dahuricae 12g, beans leaf 25g, Radix Ranunculi Ternati 5g, Radix Glycyrrhizae 8g.
Embodiment 3
A kind of Chinese medicine composition treating rosacea, its raw material of Chinese medicine and weight proportion be: Herba Crotalariae Ferrugineae 25g, Herba Hedyotidis Diffusae 10g, Flos Campsis 15g, Ludwigia octovalvis (Jacq.) Raven 5g, Folium Isatidis 20g, Rhizoma Imperatae 10g, Radix Glehniae 15g, Hibisci Mutabilis 5g, Folium Pyrrosiae 20g, Herba Solidaginis 10g, Spina Gleditsiae 15g, Radix Arnebiae (Radix Lithospermi) 5g, Radix Scrophulariae 20g, Herba Violae 10g, Radix Sophorae Flavescentis 15g, Cortex Phellodendri 5g, Mirabilitum crystallina 20g, Flos Lonicerae 10g, Rhizoma Anemarrhenae 15g, Rhizoma Polygoni Cuspidati 5g, Radix Angelicae Dahuricae 20g, beans leaf 10g, Radix Ranunculi Ternati 25g, Radix Glycyrrhizae 5g.
Embodiment 4
A kind of Chinese medicine composition treating rosacea, its raw material of Chinese medicine and weight proportion be: Herba Crotalariae Ferrugineae 10g, Herba Hedyotidis Diffusae 20g, Flos Campsis 5g, Ludwigia octovalvis (Jacq.) Raven 25g, Folium Isatidis 10g, Rhizoma Imperatae 20g, Radix Glehniae 12g, Hibisci Mutabilis 25g, Folium Pyrrosiae 5g, Herba Solidaginis 20g, Spina Gleditsiae 12g, Radix Arnebiae (Radix Lithospermi) 25g, Radix Scrophulariae 5g, Herba Violae 20g, Radix Sophorae Flavescentis 12g, Cortex Phellodendri 25g, Mirabilitum crystallina 5g, Flos Lonicerae 20g, Rhizoma Anemarrhenae 12g, Rhizoma Polygoni Cuspidati 25g, Radix Angelicae Dahuricae 5g, beans leaf 20g, Radix Ranunculi Ternati 10g, Radix Glycyrrhizae 15g.
Embodiment 5
A kind of Chinese medicine composition treating rosacea, its raw material of Chinese medicine and weight proportion be: Herba Crotalariae Ferrugineae 30g, Herba Hedyotidis Diffusae 5g, Flos Campsis 20g, Ludwigia octovalvis (Jacq.) Raven 10g, Folium Isatidis 25g, Rhizoma Imperatae 5g, Radix Glehniae 20g, Hibisci Mutabilis 10g, Folium Pyrrosiae 25g, Herba Solidaginis 5g, Spina Gleditsiae 20g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Scrophulariae 25g, Herba Violae 5g, Radix Sophorae Flavescentis 20g, Cortex Phellodendri 10g, Mirabilitum crystallina 25g, Flos Lonicerae 5g, Rhizoma Anemarrhenae 20g, Rhizoma Polygoni Cuspidati 10g, Radix Angelicae Dahuricae 15g, beans leaf 5g, Radix Ranunculi Ternati 20g, Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, added water no powder about 6 centimetres, carries out decocting for the first time, at a simmer before use intense fire to decoct, with slow fire boiling 20～30 minutes after boiling；Second time decocts, and added water no powder about 4 centimetres, decocts 15～20 minutes after water boiling.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition treating rosacea given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 75 example, male 23 examples, female 52 example, age 25～55 years old.
Two, diagnosis basis:
1, multiple middle age of being born in, women is more, is often accompanied by seborrhea；
2, send out in the middle part of face well, common with nose, two cheeks, glabella, lower chin portion, it is distributed symmetrically；
3, infringement can be divided for three phases by progress, there is no obvious boundary between each phase.The erythema phase: predominantly flush, telangiectasis.Erythema is temporary, does not then persistently move back.The papulopustule phase: acne sample pimple, pustule in batch on the basis of erythema, but formed without acne.Telangiectasis becomes apparent from.The pachydermatosis phase: nose portion forms aubergine tuberosity in expanding tumor shape, and skin surface is rough and uneven in surface, and telangiectasis is notable, and follicular orifice substantially expands, squeezable go out thick white sebum secretion thing；
4, the course of disease is slow, without obvious subjective symptoms.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice about 400ml, point morning, twice empty stomach decoction being taken warmly in evening.It within six days, it is a course for the treatment of.Avoid cold and uncooked food during treatment the thing of pungent stimulation.
Four, criterion of therapeutical effect:
1, cure: skin lesion disappears；
2, effective: part skin lesion alleviates, or disappearance more than 30%；
3, invalid: skin lesion is unchanged or disappears less than 30%.
Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, 56 examples of fully recovering, follow up a case by regular visits to have no recurrence；Effective 16 examples, invalid 3 examples.Toxic and side effects is there is not during treatment.
Six, model case:
Case 1:
Poplar, female, 39 years old.Patient's nose enlargement, skin color is aubergine, above has intensive pustule, two buccals to be also covered with red point, smears lincomycin treatment, poor effect.Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, skin aubergine shoals, and Face and cheek is red to be reduced；Continuing to take 3 courses for the treatment of, pustule calms down completely, and swelling is disappeared, and only color of the leather is slightly dark, and color of the leather recovers normal, recovery from illness.Follow up a case by regular visits to after half a year without recurrence.
Case 2:
Zhao, man, 26 years old.Between 2 years prenasal both sides of patient and two eyebrows, the big furuncle of foxtail millet grain often occurs, disappear the most voluntarily, the most constantly.After half a year, nose pore is thicker, and color of the leather reddens.Once tetracycline treatment, unsatisfactory curative effect were taken.Examining and see: nose both wings telangiectasis, follicular orifice substantially expands, squeezable go out thick white sebum secretion thing.Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, skin lesion alleviates, red thin out；Continuing to take 2 courses for the treatment of, skin lesion disappears, and cures.

Claims (2)

1. the Chinese medicine composition treating rosacea, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Crotalariae Ferrugineae 10-30 part, Herba Hedyotidis Diffusae 5-25 part, Flos Campsis 5-20 part, Ludwigia octovalvis (Jacq.) Raven 5-25 part, Folium Isatidis 5-25 part, Rhizoma Imperatae 5-25 part, Radix Glehniae 5-20 part, Hibisci Mutabilis 5-25 part, Folium Pyrrosiae 5-25 part, Herba Solidaginis 5-25 part, Spina Gleditsiae 5-20 part, Radix Arnebiae (Radix Lithospermi) 5-25 part, Radix Scrophulariae 5-25 part, Herba Violae 5-25 part, Radix Sophorae Flavescentis 5-20 part, Cortex Phellodendri 5-25 part, Mirabilitum crystallina 5-25 part, Flos Lonicerae 5-25 part, Rhizoma Anemarrhenae 5-20 part, Rhizoma Polygoni Cuspidati 5-25 part, Radix Angelicae Dahuricae 5-20 part, beans leaf 5-25 part, Radix Ranunculi Ternati 5-25 part, Radix Glycyrrhizae 5-15 part.
A kind of Chinese medicine composition treating rosacea, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Crotalariae Ferrugineae 20 parts, Herba Hedyotidis Diffusae 15 parts, Flos Campsis 10 parts, Ludwigia octovalvis (Jacq.) Raven 15 parts, Folium Isatidis 15 parts, Rhizoma Imperatae 15 parts, Radix Glehniae 10 parts, Hibisci Mutabilis 15 parts, Folium Pyrrosiae 15 parts, Herba Solidaginis 15 parts, Spina Gleditsiae 10 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Scrophulariae 15 parts, Herba Violae 15 parts, Radix Sophorae Flavescentis 10 parts, Cortex Phellodendri 15 parts, Mirabilitum crystallina 15 parts, Flos Lonicerae 15 parts, the Rhizoma Anemarrhenae 10 parts, Rhizoma Polygoni Cuspidati 15 parts, the Radix Angelicae Dahuricae 10 parts, 15 parts of beans leaf, Radix Ranunculi Ternati 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610222918.XA 2016-04-12 2016-04-12 Traditional Chinese medicinal composition for treating rosacea Pending CN105853783A (en)

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