CN105849556A - Analyte meter test strip detection - Google Patents
Analyte meter test strip detection Download PDFInfo
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- CN105849556A CN105849556A CN201480070715.2A CN201480070715A CN105849556A CN 105849556 A CN105849556 A CN 105849556A CN 201480070715 A CN201480070715 A CN 201480070715A CN 105849556 A CN105849556 A CN 105849556A
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- 239000012491 analyte Substances 0.000 title claims abstract description 71
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- 239000008103 glucose Substances 0.000 description 14
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/307—Disposable laminated or multilayered electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48785—Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply
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- Hematology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Abstract
An analyte meter (10) having a test strip port (22) is configured to detect an inserted test strip (24) by using an unpowered grounded operational amplifier (80) while the analyte meter (10) is in sleep mode. After the test strip (24) is inserted and the meter (10) is activated, the operational amplifier (80) is powered and provides the sample current for measuring an analyte concentration in the sample.
Description
Priority
This international patent application requires within 23rd, to submit in advance in December in 2013 according to Paris Convention and 35 USC § 119
The priority of U.S. Patent Application Serial Number 14/138,820, this patent application in advance is incorporated by reference accordingly.
Technical field
Present patent application relates generally to blood analyte measurement system regions, and relating more specifically to be configured to can be effectively
Detection test strip is inserted bar port circuit and need not be added the portable analysis thing tester of unnecessary switchgear to circuit.
Background technology
Blood sugar measuring system generally includes analyte test instrument, and described analyte test instrument is configured to receive generally in survey
The biosensor of test strip format.It is portable due to the many in these systems and test can be completed at short notice, because of
This patient can use this kind equipment during daily life, and will not severe jamming personal lifestyle custom.Diabetics
Its blood sugar level can be measured every day repeatedly using the part as self management's process, for guaranteeing the glycemic control amount of its blood glucose
In target zone.Target blood glucose controlled quentity controlled variable can not be kept to may result in serious diabetes-related complication, including cardiovascular disease
Disease, nephropathy, nerve injury and blind.
Presently, there are and be designed to automatically actuated multiple available portable electronics when detecting that test strip is inserted
Analysis measurement device (tester).These equipment at least some of in, the electrical contacts in instrument is built on the test strip
Stand the connection between contact pad so that voltage pulsation occurs in the testing circuit of instrument.This causes change in voltage, to instrument
Microcontroller send the signal activating resident electronic circuit, as by sample apply to insert test strip time analyze perform standard
Standby " waking up up " operation.Generally, the electrical switch in instrument disconnects or disables testing circuit with from test strip detection pattern change
For analysis measurement pattern.Electrical switch itself can consume or leakage current, even also such when switch disables, and this meeting exists
Unwanted noise source is formed during analysis measurement.The minimum electric current generating during analysis procedure and analyzing may be by this
The impact of a little leakage currents.Therefore, the more effective testing circuit implementing need not the equipment of meeting leakage current itself is favourable.
Accompanying drawing explanation
The accompanying drawing of the part being expressly incorporated herein and constitute this specification schematically shows the preferred real of the present invention at present
Execute example, and play explanation inventive feature in the lump with general description given above and fixed detailed description given below
Effect (wherein similar numbering represent similar element).
Figure 1A shows the schematic diagram of exemplary blood analyte measuring system based on test strip；
Figure 1B shows the signal of the example processing system of the blood analyte measurement system based on test strip of Figure 1A
Figure；
Fig. 2 shows another example processing system of the blood analyte measurement system based on test strip of Figure 1A
Schematic diagram；
Fig. 3 A-3B shows the work sheet of the example system institute monitoring voltage level of Fig. 2；And
Fig. 4 shows the flow chart of flow process performed by the example processing system of Fig. 2.
Detailed description of the invention
Should be read in conjunction with the accompanying drawings detailed description below, and wherein the like numbering in different accompanying drawings is identical.Accompanying drawing
(being not necessarily drawn to scale) illustrates selected embodiment, but is not intended to limit the scope of the invention.This detailed description with
Way of example and non-limiting way illustrate the principle of the present invention.This explanation will clearly make those skilled in the art
The present invention be can prepare and use, and multiple embodiments, remodeling, modification, alternative form and the purposes of the present invention described, bag
Include it is presently believed that be the best mode embodiment of the present invention.
As used herein, term " patient " or " user " refer to anyone or animal subject and be not intended as will be
System or method are confined to people and use, but the use that the present invention is in human patients represents preferred embodiment.
Term " sample " is the liquid of certain volume, solution or suspension, and described liquid, solution or suspension are intended to make
Any one of its characteristic stands to qualitatively or quantitatively determine, such as, if there is certain composition, certain composition (e.g., analyte)
Concentration etc..Embodiments of the invention are applicable to the whole blood sample of humans and animals.Typical case in invention as described herein context
Sample includes blood, blood plasma, serum, their suspension and hematocrit.
Running through the term " about " that specification and claims combines used by numerical value to represent, those skilled in the art is familiar with
And acceptable accuracy is interval.The interval controlling this term is preferably ± 10%.Unless otherwise specified, the most above-mentioned art
Language is not intended as reducing described herein and according to claim the scope of the present invention.
With reference to Figure 1A-1B, it is shown that include the analyte measuring system 100 of analyte (or test) instrument 10.Analyte is surveyed
Examination instrument 10 is limited by shell 11, and the interior size of this shell be enough to retain Data Management Unit 150 (Figure 1B), and this shell tool
There is the test strip port 22 for receiving test strip 24.According to an embodiment, analyte test instrument 10 can be blood glucose meter, and
And test strip 24 provides with the form inserting the glucose test strip 24 of the test strip port 22 for performing blood glucose measurement.According to
The analyte test instrument 10 of the present embodiment also includes multiple user interface button or keyboard 16,26 and display 14, in these
Each be arranged on the front of shell 14, FPDP 13 is arranged on one end that shell is relative with test strip port 22, as
Shown in Figure 1A.The glucose test strip of predetermined quantity is storable in shell 11, and is easily obtained for blood sugar test.Multiple
User interface button 16 can be configured to allow data input, prompting data output, navigation to present menu on display 14
And perform order.Output data can include the value such as presenting representative analyte concentration on display 14.Can pass through
The programming prompting request user's input being present on display 14, user's response to this can start order and perform maybe can wrap
Include the data in the memory module being storable in analyte test instrument 10.Specifically and according to this exemplary embodiment party
Case, user interface button 16 includes labelling, as down arrows, text character " determine " etc., thus allows user by presenting
User interface on display 14 is navigated.Although button 16 is illustrated herein as individually switching, but is used as showing
Show the touch screen interface on device 14 with virtual push button.
The electronic component of glucose measurement system 100 can be arranged on such as printed circuit board (PCB), described printed circuit board (PCB)
It is positioned at shell 11 and forms the Data Management Unit 150 of system described herein.For the purpose of this embodiment, Figure 1B with
Rough schematic view form shows the some electronic sub-systems being arranged in shell 11.Data Management Unit 150 includes processing list
(form is microprocessor, microcontroller, special IC (" ASIC "), mixed-signal processor (" MSP "), scene in unit 50
Programmable gate array (" FPGA ") or combinations thereof), and be electrically connected to include on a printed circuit or be connected to printing
The various electronic modules of circuit board, as will be described later.
Microcontroller 50 may be electrically connected to test strip port connector (" SPC ") 70, and this adapter is via AFE (analog front end)
System 90 is arranged on test strip port 22.During blood sugar test, AFE (analog front end) 90 is electrically connected to SPC 70 and microcontroller
50.In order to measure selected analyte concentration, SPC 70 is configured to detection across the electrode being arranged on analyte testing bar 24
Resistance or impedance, this analyte testing bar is electrically connected to be disposed therein the applying blood sample of sample room.Sample room can shape
Become electrochemical cell and sample, and microcontroller 50 uses manostat or transimpedance amplifier that current measurement is changed into number
Font formula is to show on display 14, and unit is usually milligram every deciliter (mg/dl) or mM every liter (mmol/l).Micro-control
Device 50 processed can be configured to receive from the input transmitting signal with sensing SPC 70 via analog front circuit 90, and this will be at this
Described in literary composition, and also can executable portion manostat function and current measurement function.
Test strip 24 can be the form of electrochemical glucose test strips.Test strip 24 can include one or more by non-conductive
The layer that material is made, material such as provide the rigidity of structure inertia or or backing material, also include one or more conductive layer, should
Conductive layer includes working electrode and the antielectrode being arranged on.Test strip 24 may also include multiple electrical contact pads, the most often
Individual electrode can electrically connect with at least one electrical contact pads.SPC 70 is configured to compliant conductive contact or contact pin electricity connects
Close electrical contact pads, and form telecommunication with electrode.Test strip 24 can include the reagent layer being arranged at least one electrode, institute
State the part that electrode forms the electrochemical cell of test strip 24.Reagent layer can include enzyme and regulator.It is applicable to reagent layer
Exemplary enzyme includes glucoseoxidase, glucose dehydrogenase (with PQQ " PQQ ") and glucose dehydrogenation
Enzyme (with flavin adenine dinucleotide (FAD) cofactor " FAD ").The exemplary adjustments agent being applicable to reagent layer includes the iron cyanide,
The iron cyanide is oxidised form in this case.Reagent layer may be configured for glucose substance is changed into enzyme by-product
Thing, and generate a certain amount of reduction regulator (the such as iron cyanide) in the process, the amount of reduction regulator and glucose
Concentration is proportional.Then, one or more working electrode can be used to measure the concentration of reducing medium in the form of electric current.Continue
And, size of current can be converted into concentration of glucose by microcontroller 50.Perform this type of exemplary analyte tester measured to exist
The U.S. Patent application of entitled " System and Method for Measuring an Analyte in a Sample "
Announcing in US 2009/0301899 A1 and be described, the full content of this patent application is incorporated by reference herein.
Can include that the display module 58 of video-stream processor and display buffer is electrically connected to micro-process by communication interface 57
Device 50, in order to receive and show output data and for showing that user interface inputs option under control of microprocessor 50.
Display interface can be accessed via microcontroller 50, present menu option with the user to blood sugar measuring system 100.User inputs mould
Block 64 can receive response input from user operation button or keyboard 16, and this input is processed and transmitted to micro-control via communication interface 63
Device 50 processed.Microcontroller 50 can electronic access to be connected to the digital dock of printed circuit board (PCB) defeated for recording blood glucose measurement and user
The date and time entered, these data can conduct interviews in later time as required, upload or show subsequently.
Communication module 60 can include the transceiver circuit for carrying out wireless digital data transmission and reception, and by logical
Letter interface 59 is electrically connected to microcontroller 50.Radio transceiver circuitry can be IC chip, chipset, the onboard storage of use
Device passes through programmable function blocks or the form of combinations thereof that microcontroller 50 operates.The compatible difference of radio transceiver circuitry
Wireless transmission standards.Such as, radio transceiver circuitry can be held concurrently with WLAN IEEE 802.11 standard of referred to as WiFi
Hold.Transceiver circuit can be configured to detect the WiFi access point near analyte test instrument 10, and transmit and receive from
The data of this WiFi access point detected.Radio transceiver circuitry can be compatible with Bluetooth protocol, and is configured to detection
With the data processed from the bluetooth Hub transport near analyte test instrument 10.Radio transceiver circuitry can be with near-field communication
(" NFC ") standard is compatible, and is configured to and the NFC that can test measured value near analyte test instrument 10 collect analyte
Compatible reader equipment sets up radio communication.Radio transceiver circuitry can include for carrying out cellular communication with cellular network
Circuit, and be configured for detection and be linked to the cellular communication tower that can use.
Onboard memory module 62 is electrically connected to microcontroller 50 by communication interface 61, onboard memory module include but
Be not limited to volatile random access memory (" RAM "), nonvolatile memory (can include read only memory (" ROM "), non-easily
The property lost RAM (NVRAM)) or flash memories, and external portable storage device can be connected to via FPDP 13.Outside
Flash memory device that storage device can include being contained in thumb actuator, portable hard disc drives, data card or any other
The electronic storage device of form.Onboard memorizer can include various Embedded Application and the program performed by microcontroller 50, uses
In operation analysis thing tester 10, as will be described later.Onboard or external memory storage can also be used for storing user blood glucose and measures
Historical record, including date and time associated there.As described herein, if using analyte 10 or FPDP 13
Wireless transmission capability, can via wired or wireless transmission by this type of data transfer to be connected computer or its elsewhere
In reason device
Power supply module 56 is electrically connected to the module in shell 11 and microcontroller 50, thus provides electricity for them
Power.Power supply module 56 can include normal cell or rechargeable battery, or can be connected to AC merit at analyte test instrument 10
Rate starts AC power source for seasonable.Power supply module 56 can be electrically connected to microcontroller 50 via communication interface 55 so that micro-
Controller 50 can monitor remaining power level in the battery of power supply module 56.
Being available for, except connecting, the external memory storage that analyte test instrument 10 uses, FPDP 13 can be additionally used in receiving attachment
To the suitable connector of connecting line, thus allow analyte test instrument 10 is wired to external device (ED), such as personal computer.Number
Can be any port that can transmit data, electric power or combinations thereof according to port 13, such as serial port, USB port or also
Row port.
With reference to prior art Figure 1B, it is shown that have bar port connector 70 and a part for front end analogue subsystem 90
Data Management Unit 150.Bar port connector 70 includes at least two working electrode 92,93, and bar detection electric contact 94.
According to the present embodiment, each in electric contact 92-94 is made into the contact being prone to in test strip 24 and electrically connects, this survey
Strip inserts bar port connector 70.Bar port connector 70 is configured to when inserting test strip 24 by switching bar 72 by electricity
Contact 92 and 94 links together, and switch bar is connected to the electrode of inserted test strip 24.Switch bar 72 can produce be transferred to micro-
The signal of controller 50, thereby indicates that test strip 24 has been inserted in bar port connector 70, as will be described later.
Referring still to Figure 1B, working electrode contacts 92 is connected to the input of operational amplifier (op-amp) 80, and computing
The output of amplifier is connected to microcontroller 50 through microcontroller interface 81.Pull-down circuit 78 (such as resistor and FET) is in work
Make to be connected between electrode contacts 92 and ground and be controlled, i.e. opened by the signal from microcontroller 50 via interface 79
And closedown.Bar detection electric contact 94 is connected to microcontroller 50 via another interface 82, and this interface is carried out by microcontroller 50
Monitoring, has inserted the test strip of bar port connector 70 for detection.Pull-up circuit 76 (such as resistor and FET) detects at bar
Being connected between electric contact 94 and voltage source Vcc, voltage source may be configured as predetermined voltage (e.g., from about 3V) controlled, i.e. via another
Interface 77 is opened and closed by the signal from microcontroller 50.
Before test strip 24 is inserted bar port connector 70, microcontroller 50 is programmed, with by analysis measurement system
System 100 is maintained under low-power or passive " sleep " pattern.During low-power mode, microcontroller 50 activates pull-down circuit 78
With pull-up circuit 76, thus working electrode contacts 92 is connected to (logical zero) and by being connected to voltage source VCCBar is examined
Survey contact 94 and be maintained at high voltage (logic 1).Thus, analog front circuit 90 can be as " digital " input circuit by microcontroller
Device 50 is monitored.In implementation process, the resistor used in pull-up circuit 76 is generally selected about 100k Ω, at drop-down electricity
The resistor used in road 78 is generally selected about 1k Ω.
When test strip 24 inserts bar port connector 70, via switch bar 72 at working electrode contacts 92 and bar detection electricity
Set up between contact 94 and be directly connected to, bar is detected the voltage on interface 82 from high (being such as equivalent to the about 3V of logic 1) switching
To low (being such as equivalent to the about 0V of logical zero).This pressure drop that microcontroller inputs at 82 sends signal to microcontroller, it is indicated that survey
Strip 24 has inserted bar port connector 70.As response, microcontroller 50 can cause and programs " waking up up " routine and activate
Tester 10 is to perform sample analysis.The part activating routine includes stopping respectively via the signal of transmission on interface 77 and 79
With pull-up circuit 76 and pull-down circuit 78.Perform to need not pull-up circuit 76 and pull-down circuit 78 when analyzing, but disable them
Do not ensure that the leakage current through these equipment also turns off, especially through being connected to the drop-down electricity of working electrode contacts 92
The electric current on road 78.At this moment, analyte test instrument 10 meeting etc. stays in applying blood sample in test strip 24, may then use that work
Electrode contacts 92,93 (and ground reference contact 95) carries out current measurement by the sample applied, every in these contacts
Individual it is connected to microcontroller 50 by operation amplifier circuit 74,80 and microcontroller interface 75,81 respectively.Due at this sample
The current measurement result the least (approximate number microampere) that performs during analysis is also determined by operational amplifier output 81 through opening
Close bar 72 and the signal of working electrode contacts 92 transmission, any leakage current in the pull-up circuit 76 disabled and pull-down circuit 78
All may the impact analysis result by introducing extraneous noise acquisition.
Relative to Fig. 2, it is shown that have a part exemplary of bar port connector 70 and analog front circuit 190
The embodiment of data association equipment (DMU) 250, wherein numbers identical element substantially worked above in association with as described in Figure 1B,
For simplicity not repeating then at this.AFE (analog front end) 190 no longer includes being attached to bar detection interface 82 or working electrode contacts
The pull-up circuit 76 of 92 and pull-down circuit 78, therefore reduce the cost of DMU 250 and eliminate potential noise source.Working electrode
Contact 92 is connected to the anti-phase input of operational amplifier 80, and the output of operational amplifier is connected to micro-control through microcontroller interface 81
Device 50 processed.Microcontroller 50 includes the switch 183 being connected to microcontroller interface 81, and this microcontroller interface can pass through microcontroller
Device 50 is selectively coupled to ground 184.Bar detection electric contact 94 is connected to microcontroller 50 via interface 82.Microcontroller includes
Being connected to the pull-up circuit 176 of interface 82, this pull-up circuit optionally can be activated by microcontroller 50, so that bar is detected contact
94 are connected to include may be configured as the voltage source V of about 3VDDInternal power supply node.
As described above, before test strip 24 is inserted bar port connector 70, microcontroller 50 is programmed, dividing
Analysis thing measurement system 100 is maintained at low-power and " sleeps " under pattern.During low-power mode, microcontroller 50 activates to be examined for bar
Survey interface 82 and the pull-up circuit 176 of bar detection contact 94 power supply.Operational amplifier 80 is also maintained at and does not leads to by microcontroller 50
Electricity condition also activates switch 183 so that microcontroller interface 81 to be connected to ground 184.Voltage source 178 is connected to operational amplifier 80
Non-inverting input.Thus the output of operational amplifier 80 is connected to via the feedback circuit being connected in parallel with operational amplifier 80
Ground 184 and working electrode contacts 92.Feedback circuit includes resistor 177 and capacitor 175, this resistor and capacitor and fortune
Calculate amplifier 80 and form the transimpedance amplifier that can work during the activity pattern of tester 10 together with voltage source 178.By
This, the interface 82 of analog front circuit 190 can be monitored by microcontroller 50 as " digital " input signal, and working method is similar to
The circuit of above-mentioned Figure 1B.Such as, the optional 33nF that is about of the size of capacitor 175, resistor 177 is about 220k Ω, voltage source
17 may be configured as about 400mV.
When test strip 24 inserts bar port connector 70, via switch bar 72 at working electrode contacts 92 and bar detection electricity
Setting up between contact 94 and connect, the voltage detected by bar on interface 82 drops to low from high (being such as equivalent to the about 3V of logic 1)
(being such as equivalent to the about 0V of logical zero).This pressure drop at microcontroller interface 82 sends signal to microcontroller, it is indicated that test strip
24 have inserted bar port connector 70.As response, microcontroller 50 can cause and programs " waking up up " routine and activate test
Instrument 10 is to perform sample analysis.The part activating routine includes disabling pull-up switch 176, thus is energized by operational amplifier 80
And open switch 183.At this moment, analyte test instrument 10 meeting etc. stays in applying blood sample in test strip 24, may then use that
Working electrode contacts 92,93 is generated and flows through the applying of sample and measure electric current, each respectively being put by computing in these contacts
Big device circuit 74,80 and microcontroller interface 75,81 are connected to microcontroller 50.If microcontroller 50 is outside lacks pull-up electricity
Road 76 and pull-down circuit 78, then mean that the leakage current thus generated does not interferes with at least sample at microcontroller interface 81
Analyze current measurement.
In order to detect the test strip 24 of insertion, can be programmed tester 10 detecting interface 82 with periodic polling bar, from
And determine whether to insert test strip, such as when being polled with the interval of about 1 second.Poll is in the sleep of tester 10
Occurring during pattern, mode is to activate pull-up circuit 176 and measure the voltage at interface 82 after preselected delay.As above institute
Stating, during sleep pattern, operational amplifier 80 is not powered on and its output on microcontroller interface 81 is by switch 183
It is connected to ground.
Fig. 3 A-3B illustrates the bar detection voltage levvl 302,303 on interface 82, and this voltage levvl is being surveyed by microcontroller 50
Strip 24 is not inserted into (Fig. 3 A) bar port connector 70 and test strip 24 is surveyed when inserting (Fig. 3 B) bar port connector 70 respectively
Measure and obtain.Seeing Fig. 3 A, polling sequence starts from, at about 60 μ s, the most having activated pull-up circuit 176 so that bar is detected interface
82 are connected to voltage source VDD, wherein the voltage levvl on bar detection interface 82 rises to about 3V immediately.Preliminary election at about 15 μ s is prolonged
After Chi, during activating, sense the voltage levvl of bar detection interface 82, i.e. from the beginning of about 75 μ s to about 85 μ s, microcontroller
The level high of sensing circuit measurement window 304.The about 3V level high 302 of microcontroller sensing bar detection interface 82
(i.e. logic or numeral 1), thus indicate test strip not yet to insert bar port connector 70 microcontroller 50, cause microcontroller
Tester is maintained at low-power sleep mode by 50, until poll next time.With reference to Fig. 3 B, the poll work of the test strip that detection is inserted
Sequence starts at about 60 μ s, activates pull-up circuit 76 the most as described above and is connected to voltage source V so that bar to detect interface 82DD.?
After the preselected delay of about 15 μ s, during activating, sense the voltage levvl of bar detection interface 82, i.e. from about 75 μ s to about 85 μ
S starts, the level high of microcontroller sensing circuit measurement window 304.The pact of microcontroller sensing bar detection interface 82
The low voltage levels of 0.2V 303 (i.e. logic or numeral 0), thus indicate test strip to insert bar port connector microcontroller 50
70, cause microcontroller 50 to start the wake-up activation operation of tester 10, as previously discussed.Lead to bar being detected signaling interface 82
About 15 μ s preselected delay after electricity provide time window 304, and wherein the voltage levvl of bar detection interface 82 is not inserted in test strip
Voltage levvl 302 and test strip have been inserted notable differentiation between voltage levvl 303, therefore microcontroller 50 can pass through numeral side
Formula (logical zero/1) distinguishes difference.As shown in Figure 3 B, bar detection interface voltage 303 continues to rise after inserting test strip 24.Cause
This, read for numeral accurately, and it can measure voltage levvl thereon the most earlier rather than more behindhand.
With reference to Fig. 4, it is shown that operation analysis thing measures the flow chart of the method for the embodiment of system 100.In step 401
In, analyte measuring system 100 is maintained under the low-power inactive sleep pattern of acquiescence.Sleep pattern is kept to include testing
Operational amplifier 80 power-off of instrument, such as by disconnecting or closing its power supply and be connected to ground by the output of operational amplifier
184.In step 402, the voltage levvl of bar detection interface 82 is periodically sensed by analyte measuring system 100.If felt
The voltage levvl surveyed is the level high being equivalent to logical one, the most in step 403, is programmed by analyte measuring system 100
For continuing periodic polling bar detection interface 82.If the voltage levvl sensed is the low voltage level being equivalent to digital " 0 ", then
In step 404, analyte measuring system 100 is programmed for activate analog front circuit 190 to perform analysis measurement, including
Operational amplifier is energized, such as by being connected to its power supply or opening its power supply and output it and ground
184 disconnect.In step 405, perform analysis measurement, be included in the amount measuring electric current at the output 81 of operational amplifier 80
Level.
It will be understood by those of skill in the art that various aspects of the invention can be implemented as processing system, method or set
Standby.Therefore, various aspects of the invention can use following form: hardware embodiments, complete Software implementations completely (includes
Firmware, resident software, microcode etc.) or combine software and hardware aspect and (can be collectively referred to as " circuit ", " Circuits System ", " mould herein
Block ", " subsystem " and/or " system ") embodiment.Additionally, the aspect of the present invention can be taked to be embedded in one or more meter
Computer program product in calculation machine computer-readable recording medium (this computer-readable medium have be embedded in computer calibration program thereon)
The form of product.
Performed computing and the program code of measurement and/or data represent can use any suitable media storage, including
But it is not limited to the combination in any of one or more computer-readable medium.Computer-readable recording medium can be such as electricity, magnetic
Property, optics, electromagnetism, infrared or semiconductor system, equipment or device or their any appropriate combination.Computer-readable stores
The more concrete example of medium will include following medium: have the electrical connection of one or more wire, portable computer diskette,
Hard disk, RAM memory, ROM, NVRAM, EPROM, flash memories, optical fiber, portable optic disk read only memory (CD-ROM),
Optical storage, magnetic memory apparatus or their any appropriate combination.In context of this document, computer-readable stores
Medium can be any tangible, medium of non-transitory, and described medium can include or store for instruction execution system, equipment or dress
Put use or combined command performs the program that system, equipment or device use.
Performed computing and the program code of measurement and/or data represent any suitable medium can be used to be transmitted,
Described medium includes but not limited to wireless, Wireline, fiber optic cables, RF or their any appropriate combination.
The component list of Figure 1A-4
10 analyte test instruments
11 shells, instrument
13 FPDPs
14 display
16 user interface button/keyboard
22 test strip ports
24 test strip
50 microcontrollers (processing unit)
55 power supply interfaces
56 power supplies
57 display module interfaces
58 display modules
59 communication module interfaces
60 communication modules
61 storage module interfaces
62 memory modules
63 buttons/keys dish interfaces
64 buttons/keys disk modules
Article 70, port connector
72 switch bars
74 operational amplifiers
75 microcontroller interfaces
76 pull-up circuits
77 microcontroller interfaces
78 pull-down circuits
79 microcontroller interfaces
80 operational amplifiers
81 microcontroller interfaces
Article 82, detection interface
90 analog front circuits
92 working electrode contacts
93 working electrode contacts
Article 94, detection contact
95 ground reference
100 analyte measuring systems
150 Data Management Unit
Article 170, port connector
175 capacitors
176 pull-up circuits
177 resistors
178 voltage sources
183 switches
184 ground
190 analog front circuits
250 Data Management Unit
Article 302, detection voltage levvl, test strip is not inserted into
Article 303, detection voltage levvl, test strip is inserted
304 measurement window
401 steps-by analyte test instrument are maintained at sleep pattern: by operational amplifier power-off, operational amplifier is defeated
Go out to be connected to ground
402 steps-sensing bar detection voltage
403 decision-bar detection voltages are low？
404 steps-activation analysis thing tester: be energized by operational amplifier, disconnects operational amplifier output with ground
Analysis electric current in the output of 405 steps-measuring operational amplifier
Although the present invention is described according to concrete modification and exemplary picture, the ordinary skill people of this area
Member is it will be appreciated that the invention is not restricted to send the change of description or picture.Additionally, indicate in above-mentioned method and steps with certain
In the case of there is some event in order, those of ordinary skill in the art it will be recognized that the order of some step can be modified,
And this type of amendment is according to variant of the invention.It addition, some step is in addition to can performing the most in order,
Can also perform in parallel procedure in the case of Ke Neng simultaneously.Therefore, this patent is intended to variant of the invention, as long as this
In a little modification are in the essence of the disclosure occurred in the claims or it is equal to the present invention.
Claims (20)
1. an analyte test instrument, including:
Bar port connector, described bar port connector is configured to receive analysis based on the electrochemistry test being inserted
Bar；
Being electrically connected to the front-end circuit of described analytical test strip, described front-end circuit includes operational amplifier, described operation amplifier
Device is for defeated at it corresponding to applying to the sample analysis substrate concentration of described analytical test strip when described operational amplifier is energized
Signal is provided at egress；With
Be connected to voltage supply and ground bar signal lines, wherein described operational amplifier be in be not powered on state time ground connection
Connect through the described output node of described operational amplifier and pass through inserted test strip and provide.
Analyte test instrument the most according to claim 1, wherein by the described output node of described operational amplifier
Described grounding connection includes the feedback circuit in parallel with described operational amplifier.
Analyte test instrument the most according to claim 2, wherein said feedback circuit include the capacitor that is connected in parallel and
Resistor.
Analyte test instrument the most according to claim 3, wherein said analyte test instrument is configured with activity pattern and sleeps
Sleep mode, and described in wherein said operational amplifier, it is not powered on the state described sleep corresponding to described analyte test instrument
Pattern.
Analyte test instrument the most according to claim 3, wherein said operational amplifier is supplied by described analyte test instrument
Electricity, with respond described analyte test instrument described bar detection line on sense described ground voltage.
Analyte test instrument the most according to claim 1, is wherein not inserted into described bar port connector in described test strip
Shi Suoshu voltage supply promotes described bar signal lines to be in digital high voltage level.
Analyte test instrument the most according to claim 1, is wherein programmed for described analyte test instrument examining at described bar
Survey and on holding wire, periodically sense described voltage.
8. an analyte test instrument, including:
Bar port connector, described bar port connector is for receiving the test strip being inserted and measuring described test strip
The analyte level of sample in sample room；
Working-electrode circuit, described working-electrode circuit can be connected to when described test strip inserts described bar port connector
Ground and the described sample being connectable in inserted test strip, for generating corresponding to analyzing described in described sample
The signal of thing level, described working-electrode circuit includes operational amplifier；With
Microcontroller, described microcontroller is connected to the output of described operational amplifier, for receiving from which corresponding to institute
State the described signal of analyte level described in sample and the described output of described operational amplifier is connected to ground, for
Bar detection signal is generated when described test strip inserts described bar port connector.
Analyte test instrument the most according to claim 8, is additionally included in described test strip and inserts described bar port connector
Time be connected to the bar signal lines of described working-electrode circuit.
Analyte test instrument the most according to claim 9, wherein ground voltage level includes that described bar detects signal, and
Wherein said bar detection signal is transferred to described microcontroller through described bar signal lines.
11. analyte test instruments according to claim 10, also include that sleep state, wherein said operational amplifier do not lead to
Electricity, and wherein said test strip is not inserted into described bar port connector.
12. analyte test instruments according to claim 11, wherein described bar detection signal during described sleep state
Line is in logical one voltage level.
13. analyte test instruments according to claim 12, wherein said working-electrode circuit also includes being connected to described
The feedback circuit of operational amplifier, described feedback circuit includes capacitor and the resistor being connected in parallel.
14. analyte test instruments according to claim 11, wherein said microcontroller by described analyte test instrument from
Described sleep state switches to active state and is energized by described operational amplifier in response to receiving described bar detection signal.
15. analyte test instruments according to claim 14, wherein said microcontroller is in response to receiving the detection of described bar
Signal and the described output of described operational amplifier is disconnected with described.
16. analyte test instruments according to claim 13, wherein said working-electrode circuit is connected to described computing and puts
The anti-phase input of device, and reference voltage source greatly is connected to the non-inverting input of described operational amplifier.
The method of 17. 1 kinds of operation analysis thing testers, described analyte test instrument has bar port connector and measuring circuit,
Described bar port connector is configured to receive the test strip being inserted, and described measuring circuit is for measuring the test inserted
The analyte level of sample in bar, described method includes:
When not receiving bar detection signal, described analyte test instrument is made to be maintained under low-power inactive mode；
Detect signal periodic monitoring bar signal lines for described bar, be connected to voltage including by described bar signal lines
Source；
Configure described bar signal lines and described measuring circuit so that the test strip inserted is by described bar signal lines coupling
Receive the ground connection output of operational amplifier to generate described bar detection signal；And
In response to receiving described bar detection signal, described analyte test instrument is switched to from described low-power inactive mode
Activity pattern.
18. methods according to claim 17, wherein said make analyte test instrument be maintained at low-power inactive mode
Under step also include described operational amplifier power-off, and the output of described operational amplifier is connected to ground.
19. methods according to claim 18, the wherein said step bag that analyte test instrument is switched to activity pattern
Include and described operational amplifier is energized, and output it and disconnect with described.
20. methods according to claim 19, also include measuring the described analysis of sample described in the test strip inserted
Thing level, including the levels of current of the described output measuring described energising operational amplifier.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/138820 | 2013-12-23 | ||
| US14/138,820 US9442089B2 (en) | 2013-12-23 | 2013-12-23 | Analyte meter test strip detection |
| PCT/EP2014/078990 WO2015097151A1 (en) | 2013-12-23 | 2014-12-22 | Analyte meter test strip detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105849556A true CN105849556A (en) | 2016-08-10 |
| CN105849556B CN105849556B (en) | 2019-06-04 |
Family
ID=52395024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480070715.2A Expired - Fee Related CN105849556B (en) | 2013-12-23 | 2014-12-22 | The detection of analyte test instrument test-strips |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9442089B2 (en) |
| EP (1) | EP3087389A1 (en) |
| JP (1) | JP6483708B2 (en) |
| KR (1) | KR20160102240A (en) |
| CN (1) | CN105849556B (en) |
| AU (1) | AU2014372668A1 (en) |
| CA (1) | CA2934765A1 (en) |
| HK (1) | HK1231552A1 (en) |
| RU (1) | RU2672111C2 (en) |
| WO (1) | WO2015097151A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110869746A (en) * | 2017-08-17 | 2020-03-06 | 雅培医护站股份有限公司 | Techniques for performing optical and electrochemical assays using universal circuitry |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180172664A1 (en) | 2016-12-20 | 2018-06-21 | Abbott Diabetes Care Inc. | Systems, devices, and methods for wireless communications in analyte monitoring systems |
| EP3759465B1 (en) * | 2018-02-26 | 2023-08-02 | F. Hoffmann-La Roche AG | Methods and systems for calibrating and using a camera for detecting an analyte in a sample |
| DE102018208049A1 (en) * | 2018-05-23 | 2019-11-28 | Robert Bosch Gmbh | Framework structure for interaction with an image evaluation device for at least one at least one optochemical detection surface having carrier |
| EP4039520A3 (en) * | 2021-02-09 | 2022-10-26 | Hyundai Mobis Co., Ltd. | Vehicle display device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070170073A1 (en) * | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Method and System for Detecting Age, Hydration, and Functional States of Sensors Using Electrochemical Impedance Spectroscopy |
| AU2008265610A1 (en) * | 2007-06-21 | 2008-12-24 | Gen-Probe Incorporated | Instrument and receptacles for performing processes |
| CN102116743A (en) * | 2009-12-31 | 2011-07-06 | 北京硕泰汇丰科技有限公司 | Portable urine analyzer |
| CN103002795A (en) * | 2010-05-09 | 2013-03-27 | 拉布斯戴尔创新有限公司 | Fluids testing apparatus and methods of use |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK115989D0 (en) * | 1989-03-09 | 1989-03-09 | Nordisk Gentofte | METHOD AND METHOD FOR MEASURING A LIQUID COMPONENT |
| AU7017994A (en) * | 1993-06-08 | 1995-01-03 | Boehringer Mannheim Corporation | Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips |
| US7267948B2 (en) | 1997-11-26 | 2007-09-11 | Ut-Battelle, Llc | SERS diagnostic platforms, methods and systems microarrays, biosensors and biochips |
| US6635167B1 (en) * | 1997-12-04 | 2003-10-21 | Roche Diagnostics Corporation | Apparatus and method for determining the concentration of a component of a sample |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6509796B2 (en) | 2000-02-15 | 2003-01-21 | Broadcom Corporation | Variable transconductance variable gain amplifier utilizing a degenerated differential pair |
| JP2003528312A (en) | 2000-03-22 | 2003-09-24 | オールメディカス カンパニー リミテッド | Electrochemical biosensor test strip having recognition electrode and measuring device using the same |
| US6525330B2 (en) | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
| US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
| US7557353B2 (en) | 2001-11-30 | 2009-07-07 | Sicel Technologies, Inc. | Single-use external dosimeters for use in radiation therapies |
| US6946299B2 (en) * | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US6743635B2 (en) | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
| US20040118704A1 (en) * | 2002-12-19 | 2004-06-24 | Yi Wang | Analyte test intrument having improved versatility |
| JP2004233294A (en) * | 2003-01-31 | 2004-08-19 | Tanita Corp | Electrochemical sensor measuring device and its measuring method |
| US7964146B2 (en) | 2004-05-30 | 2011-06-21 | Agamatrix, Inc. | Measuring device and methods for use therewith |
| US9636450B2 (en) | 2007-02-19 | 2017-05-02 | Udo Hoss | Pump system modular components for delivering medication and analyte sensing at seperate insertion sites |
| AU2006226988B2 (en) | 2005-03-21 | 2011-12-01 | Abbott Diabetes Care, Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
| US20070169533A1 (en) | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Methods and systems for detecting the hydration of sensors |
| EP1990634A4 (en) | 2006-02-27 | 2015-05-06 | Sumitomo Electric Industries | Biosensor chip, biosensor system, and measuring device thereof |
| US7943034B2 (en) | 2006-10-19 | 2011-05-17 | Agamatrix, Inc. | Method and apparatus for providing a stable voltage to an analytical system |
| US7794658B2 (en) | 2007-07-25 | 2010-09-14 | Lifescan, Inc. | Open circuit delay devices, systems, and methods for analyte measurement |
| WO2009059194A1 (en) | 2007-11-02 | 2009-05-07 | Edwards Lifesciences Corporation | Analyte monitoring system capable of detecting and providing protection against signal noise generated by external systems that may affect the monitoring system |
| JP2009121996A (en) * | 2007-11-15 | 2009-06-04 | Sumitomo Electric Ind Ltd | Biosensor system and measuring instrument therefor |
| JP2009180545A (en) * | 2008-01-29 | 2009-08-13 | Sumitomo Electric Ind Ltd | Biosensor correction chip and biosensor system |
| US8551320B2 (en) | 2008-06-09 | 2013-10-08 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
| US20110057671A1 (en) | 2009-09-04 | 2011-03-10 | Lifescan Scotland, Ltd. | Methods, system and device to identify a type of test strip |
| US8742773B2 (en) | 2010-02-25 | 2014-06-03 | Lifescan Scotland Limited | Capacitance detection in electrochemical assay with improved response |
| US8603323B2 (en) | 2010-09-20 | 2013-12-10 | Lifescan, Inc. | Apparatus and process for improved measurements of a monitoring device |
| CA2823180C (en) | 2010-12-31 | 2018-10-23 | Ronald C. Chatelier | Systems and methods for high accuracy analyte measurement |
| EP2681538B1 (en) | 2011-03-11 | 2019-03-06 | Mc10, Inc. | Integrated devices to facilitate quantitative assays and diagnostics |
| US8623660B2 (en) | 2011-09-30 | 2014-01-07 | Lifescan Scotland Limited | Hand-held test meter with phase-shift-based hematocrit measurement circuit |
| US8896292B2 (en) | 2011-12-22 | 2014-11-25 | Semiconductor Components Industries, Llc | System and method for gain adjustment in transimpedance amplifier configurations for analyte measurement |
| US9903830B2 (en) | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
| JP6404681B2 (en) * | 2013-11-08 | 2018-10-10 | アークレイ株式会社 | Measuring apparatus and measuring method |
-
2013
- 2013-12-23 US US14/138,820 patent/US9442089B2/en active Active
-
2014
- 2014-12-22 EP EP14830386.0A patent/EP3087389A1/en not_active Withdrawn
- 2014-12-22 WO PCT/EP2014/078990 patent/WO2015097151A1/en active Application Filing
- 2014-12-22 JP JP2016541516A patent/JP6483708B2/en not_active Expired - Fee Related
- 2014-12-22 AU AU2014372668A patent/AU2014372668A1/en not_active Abandoned
- 2014-12-22 CN CN201480070715.2A patent/CN105849556B/en not_active Expired - Fee Related
- 2014-12-22 RU RU2016129889A patent/RU2672111C2/en not_active IP Right Cessation
- 2014-12-22 KR KR1020167019565A patent/KR20160102240A/en not_active Application Discontinuation
- 2014-12-22 CA CA2934765A patent/CA2934765A1/en not_active Abandoned
-
2017
- 2017-04-11 HK HK17103701.5A patent/HK1231552A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070170073A1 (en) * | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Method and System for Detecting Age, Hydration, and Functional States of Sensors Using Electrochemical Impedance Spectroscopy |
| AU2008265610A1 (en) * | 2007-06-21 | 2008-12-24 | Gen-Probe Incorporated | Instrument and receptacles for performing processes |
| CN102116743A (en) * | 2009-12-31 | 2011-07-06 | 北京硕泰汇丰科技有限公司 | Portable urine analyzer |
| CN103002795A (en) * | 2010-05-09 | 2013-03-27 | 拉布斯戴尔创新有限公司 | Fluids testing apparatus and methods of use |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110869746A (en) * | 2017-08-17 | 2020-03-06 | 雅培医护站股份有限公司 | Techniques for performing optical and electrochemical assays using universal circuitry |
| CN110869746B (en) * | 2017-08-17 | 2023-08-11 | 雅培医护站股份有限公司 | Techniques for performing optical and electrochemical assays using universal circuitry |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105849556B (en) | 2019-06-04 |
| KR20160102240A (en) | 2016-08-29 |
| EP3087389A1 (en) | 2016-11-02 |
| JP6483708B2 (en) | 2019-03-13 |
| RU2672111C2 (en) | 2018-11-12 |
| AU2014372668A1 (en) | 2016-06-30 |
| US20150177176A1 (en) | 2015-06-25 |
| JP2017500571A (en) | 2017-01-05 |
| HK1231552A1 (en) | 2017-12-22 |
| US9442089B2 (en) | 2016-09-13 |
| CA2934765A1 (en) | 2015-07-02 |
| WO2015097151A1 (en) | 2015-07-02 |
| RU2016129889A (en) | 2018-01-30 |
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