CN105848653A - 用于治疗多发性硬化症的拉喹莫德联合治疗 - Google Patents
用于治疗多发性硬化症的拉喹莫德联合治疗 Download PDFInfo
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- CN105848653A CN105848653A CN201480053575.8A CN201480053575A CN105848653A CN 105848653 A CN105848653 A CN 105848653A CN 201480053575 A CN201480053575 A CN 201480053575A CN 105848653 A CN105848653 A CN 105848653A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
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- A—HUMAN NECESSITIES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Neurology (AREA)
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- Dispersion Chemistry (AREA)
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- Zoology (AREA)
- Pulmonology (AREA)
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- Immunology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201361883698P | 2013-09-27 | 2013-09-27 | |
| US61/883,698 | 2013-09-27 | ||
| PCT/US2014/057705 WO2015065628A2 (en) | 2013-09-27 | 2014-09-26 | Laquinimod combination therapy for treatment of multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
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| CN105848653A true CN105848653A (zh) | 2016-08-10 |
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| US (3) | US20150094332A1 (https=) |
| EP (1) | EP3049075A4 (https=) |
| JP (1) | JP2016533323A (https=) |
| KR (1) | KR20160085757A (https=) |
| CN (1) | CN105848653A (https=) |
| AR (1) | AR097792A1 (https=) |
| AU (1) | AU2014342917A1 (https=) |
| BR (1) | BR112016006582A2 (https=) |
| CA (1) | CA2925493A1 (https=) |
| EA (1) | EA201690673A1 (https=) |
| IL (1) | IL244620A0 (https=) |
| MX (1) | MX2016003763A (https=) |
| SG (1) | SG11201602175VA (https=) |
| TW (1) | TW201601722A (https=) |
| UY (1) | UY35748A (https=) |
| WO (1) | WO2015065628A2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201692180A1 (ru) | 2014-04-29 | 2017-08-31 | Тева Фармасьютикал Индастриз Лтд. | Лахинимод для лечения пациентов с рецидивирующе-ремиттирующим рассеянным склерозом (рррс) с высоким статусом инвалидизации |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325302A (zh) * | 1998-11-19 | 2001-12-05 | 富马法姆股份公司 | 富马酸二烷基酯的用途 |
| US20080227847A1 (en) * | 2005-07-07 | 2008-09-18 | Aditech Pharma Ab | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use |
| CN102802415A (zh) * | 2009-06-19 | 2012-11-28 | 泰华制药工业有限公司 | 利用拉喹莫德治疗多发性硬化 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS52169B (sr) * | 2006-06-12 | 2012-08-31 | Teva Pharmaceutical Industries Limited | Stabilni preparati lakvinimoda |
| EA201490377A1 (ru) * | 2011-07-28 | 2014-11-28 | Тева Фармасьютикал Индастриз Лтд. | Лечение рассеянного склероза комбинацией лаквинимода и глатирамера ацетата |
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2014
- 2014-09-26 CA CA2925493A patent/CA2925493A1/en active Pending
- 2014-09-26 TW TW103133660A patent/TW201601722A/zh unknown
- 2014-09-26 SG SG11201602175VA patent/SG11201602175VA/en unknown
- 2014-09-26 EA EA201690673A patent/EA201690673A1/ru unknown
- 2014-09-26 EP EP14857795.0A patent/EP3049075A4/en not_active Withdrawn
- 2014-09-26 AR ARP140103582A patent/AR097792A1/es unknown
- 2014-09-26 US US14/498,024 patent/US20150094332A1/en not_active Abandoned
- 2014-09-26 CN CN201480053575.8A patent/CN105848653A/zh active Pending
- 2014-09-26 MX MX2016003763A patent/MX2016003763A/es unknown
- 2014-09-26 KR KR1020167011039A patent/KR20160085757A/ko not_active Withdrawn
- 2014-09-26 AU AU2014342917A patent/AU2014342917A1/en not_active Abandoned
- 2014-09-26 JP JP2016516547A patent/JP2016533323A/ja not_active Withdrawn
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- 2014-09-26 WO PCT/US2014/057705 patent/WO2015065628A2/en not_active Ceased
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2016
- 2016-03-15 IL IL244620A patent/IL244620A0/en unknown
- 2016-05-31 US US15/169,139 patent/US20160271094A1/en not_active Abandoned
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2017
- 2017-07-06 US US15/643,214 patent/US20170304253A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325302A (zh) * | 1998-11-19 | 2001-12-05 | 富马法姆股份公司 | 富马酸二烷基酯的用途 |
| US20080227847A1 (en) * | 2005-07-07 | 2008-09-18 | Aditech Pharma Ab | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use |
| CN102802415A (zh) * | 2009-06-19 | 2012-11-28 | 泰华制药工业有限公司 | 利用拉喹莫德治疗多发性硬化 |
Non-Patent Citations (3)
| Title |
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| CLAUDIO GASPERINI等: "Emerging oral drugs for multiple sclerosis", 《EXPERT OPINION EMERGING DRUGS》 * |
| JEFFREY A. COHEN: "The future of multiple sclerosis treatment", 《JOURNAL OF THE NEUROLOGICAL SCIENCES》 * |
| 张金妮等: "多发性硬化早期表现为临床孤立综合征79 例临床分析", 《中国神经免疫学和神经病学杂志》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20170304253A1 (en) | 2017-10-26 |
| EP3049075A4 (en) | 2017-05-03 |
| JP2016533323A (ja) | 2016-10-27 |
| AR097792A1 (es) | 2016-04-13 |
| EP3049075A2 (en) | 2016-08-03 |
| WO2015065628A2 (en) | 2015-05-07 |
| CA2925493A1 (en) | 2015-05-07 |
| KR20160085757A (ko) | 2016-07-18 |
| TW201601722A (zh) | 2016-01-16 |
| SG11201602175VA (en) | 2016-04-28 |
| US20150094332A1 (en) | 2015-04-02 |
| MX2016003763A (es) | 2016-10-28 |
| UY35748A (es) | 2015-04-30 |
| US20160271094A1 (en) | 2016-09-22 |
| BR112016006582A2 (pt) | 2017-08-01 |
| IL244620A0 (en) | 2016-04-21 |
| WO2015065628A3 (en) | 2015-10-29 |
| AU2014342917A1 (en) | 2016-04-21 |
| EA201690673A1 (ru) | 2016-08-31 |
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