CN105833217A - Preparation method of muscle and bone membrane - Google Patents

Preparation method of muscle and bone membrane Download PDF

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Publication number
CN105833217A
CN105833217A CN201610223433.2A CN201610223433A CN105833217A CN 105833217 A CN105833217 A CN 105833217A CN 201610223433 A CN201610223433 A CN 201610223433A CN 105833217 A CN105833217 A CN 105833217A
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parts
radix
rhizoma
preparation
carrying
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李颖
王洪珍
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TONGHUA WANTONG PHARMACEUTICAL CO Ltd
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TONGHUA WANTONG PHARMACEUTICAL CO Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/57—Magnoliaceae (Magnolia family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses a preparation method of a muscle and bone membrane. The preparation method comprises the following steps: weighing the medicinal materials including rhizoma corydalis and rhizoma zingiberis according to the weight parts, smashing the medicinal materials respectively to obtain coarse powder, mixing the coarse powder to obtain a mixed material, steeping the mixed material by adopting 70% of ethyl alcohol at 25 DEG C for 24h, carrying out percolation by adopting 70% of ethyl alcohol and using a percolation method to obtain a percolate for later use; adding with 85% of ethyl alcohol according to the weight ratio of polyvinyl alcohol to the 85% of ethyl alcohol being 1 to (3-5), carrying out drying, thus obtaining a mixture, adding water into the mixture, carrying out heating till the mixture is dissolved, and carrying out uniform mixing, thus obtaining a base material; and taking glycerinum, azone, camphor and menthol according to the weight parts, adding with water till the preparation amount is reached, carrying out uniform stirring, carrying out filtering, and carrying out split charging, thus obtaining the muscle and bone membrane. The muscle and bone membrane can inhibit the platelet aggregation, and has the inhibiting effect for the permeability increase of the coeliac capillaries, in the preparation process, the preparation environment is steady, the dramatic physical and chemical changes of the components are avoided, and finally, the efficacies and the purity of the muscle and bone membrane are improved.

Description

The preparation method of one analgesic bone film
Technical field
The present invention relates to the preparation method of an analgesic bone film.
Background technology
Muscles and bones film is mainly used in hyperosteogeny, cervical spondylosis, arthritis, muscular soreness, scapulohumeral periarthritis, vertebra Intercalated disc is prominent, urgency/chronic torsion, contusion, traumatic injury stasis of blood pain, fracture, rheumatism and the tatanic ridge of rheumatoid pain The pain that vertebra is scorching, Senile osteoarthritis causes.Women sickness rate is slightly above male, is more common in muscle power Labourer.If treated not in time, it is possible to have a strong impact on the movable function in joint, patient local, often Because of Changes in weather and tired induction, can gradually develop into rest pain later, and progressively increase the weight of, make Locally the actively and passively activity in all directions of joint is the most restricted, even causes amyotrophy.Existing There is the preparation technology flow process in technology the most complicated, preparation process easily cause the waste of raw material, It is also easy to make raw material produce bigger physicochemical change in preparation process, affects drug effect.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, it is an object of the invention to provide the preparation of an analgesic bone film Method, to obtain the muscles and bones film of a kind of high curative effect.
Technical scheme is as follows:
The preparation method of one analgesic bone film, it comprises the following steps:
A, weigh according to weight portion Rhizoma Corydalis, Rhizoma Zingiberis, Herba speranskiae tuberculatae, Rhizoma Et Radix Notopterygii, Rhizoma Kaempferiae, Cortex Cinnamomi, Radix Stephaniae Tetrandrae, Radix Et Rhizoma Nardostachyos, Cortex Acanthopancis, Fructus Capsici, Semen Sinapis Albae, Pericarpium Zanthoxyli, Flos Carthami, Herba Taxilli, Radix Dipsaci, Radix Clematidis, stretch Muscle grass, Radix Gentianae Macrophyllae, Cortex Illicii and Lignum Sappan, be respectively crushed into coarse powder by above-mentioned medical material and be mixed to get batch mixing, It is sufficiently mixed, under the conditions of 25 DEG C according to the ratio that part by weight is 1: 1.5-2.5 of batch mixing and 70% ethanol Impregnating 24 hours, carry out percolation with 70% ethanol by percolation the most again, it is standby that collection obtains percolate；
B, according to weight portion weighing polyvinyl alcohol, according to the part by weight of polyvinyl alcohol and 85% ethanol be The ratio of 1: 3-5 adds 85% ethanol, soaks 12 hours under the conditions of 25 DEG C, takes out, and dries, obtains Mixture, then according to mixture and the ratio that part by weight is 1: 1-3 of water, adds water in mixture It is heated to dissolving, stirs, obtain substrate；
C, take glycerol, azone, Camphora and Mentholum according to weight portion, be then added into above-mentioned gained The eutectic mixture that in substrate, co-ground is formed, stirs, then by above-mentioned gained percolate limit Edged stirring joins in the middle of eutectic mixture, is adding water to amount of preparation, is stirring, and filters, Subpackage, obtains described muscles and bones film.
Described preparation method, wherein, the component of above-mentioned muscles and bones film includes according to weight portion:
The Rhizoma Corydalis of 20 parts-30 parts, the Rhizoma Zingiberis of 40 parts-60 parts, the Herba speranskiae tuberculatae of 20 parts-30 parts, 20 part-30 Part Rhizoma Et Radix Notopterygii, the Rhizoma Kaempferiae of 30 parts-50 parts, the Cortex Cinnamomi of 20 parts-30 parts, the Radix Stephaniae Tetrandrae of 20 parts-30 parts, The Radix Et Rhizoma Nardostachyos of 20 parts-40 parts, the Cortex Acanthopancis of 20 parts-30 parts, the Fructus Capsici of 40 parts-60 parts, 20 parts-40 parts Semen Sinapis Albae, the Pericarpium Zanthoxyli of 5 parts-15 parts, the Flos Carthami of 5 parts-15 parts, the Herba Taxilli of 20 parts-40 parts, 20 The Radix Dipsaci of parts-40 parts, the Lignum Sappan of 10 parts-20 parts, the Radix Clematidis of 20 parts-30 parts, 20 parts-30 parts Herba Lycopodii, the Cortex Illicii of 20 parts-30 parts, the Radix Gentianae Macrophyllae of 20 parts-30 parts, the Mentholum of 20 parts-30 parts, The Camphora of 20 parts-30 parts, the polyvinyl alcohol of 50 parts-70 parts, the glycerol of 40 parts-60 parts and 20 part-30 The azone of part.
The preparation method of the analgesic bone film that the present invention provides, has anti-soft tissue injury, antiinflammatory, town Pain and the effect of blood circulation promoting and blood stasis dispelling, in treating rat skin ecchymosis, can dramatically speed up the dermal ecchymosis Dissipation and improvement；In treatment to rat traumatic soft tissue injury, can obviously improve and hinder limb damage Degree, alleviates the pathological changes such as wound local organization blood stasis, swelling and cell infiltration, to Fructus Crotonis Oil causes mice ear, carrageenin causes rat paw edema, Freund's complete adjuvant causes experimental immune and closes The arthroncus that joint inflammation causes has significant inhibitory action, is turning round mice thermostimulation tail-flick method and acetic acid The pain reaction that body method causes has significant inhibitory action, and the muscles and bones film of the present invention can reduce whole blood and glue Degree, suppresses platelet aggregation, and caused by Dichlorodiphenyl Acetate, abdominal cavity capillary permeability raises all inhibitory action, and And in preparation process to prepare environment ratio shallower, it is to avoid each component produces violent physico Learn change, improve drug effect and the purity of muscles and bones film.
Detailed description of the invention
The invention provides the preparation method of an analgesic bone film, for making the purpose of the present invention, technical scheme And effect is clearer, clear and definite, the present invention is described in more detail below.Should be appreciated that herein Described specific embodiment, only in order to explain the present invention, is not intended to limit the present invention.
The invention provides the preparation method of an analgesic bone film, it comprises the following steps:
Step 101: according to weight portion weigh Rhizoma Corydalis, Rhizoma Zingiberis, Herba speranskiae tuberculatae, Rhizoma Et Radix Notopterygii, Rhizoma Kaempferiae, Cortex Cinnamomi, Radix Stephaniae Tetrandrae, Radix Et Rhizoma Nardostachyos, Cortex Acanthopancis, Fructus Capsici, Semen Sinapis Albae, Pericarpium Zanthoxyli, Flos Carthami, Herba Taxilli, Radix Dipsaci, prestige Radix Clematidis, Herba Lycopodii, Radix Gentianae Macrophyllae, Cortex Illicii and Lignum Sappan, be respectively crushed into coarse powder by above-mentioned medical material and mix Obtain batch mixing, be sufficiently mixed according to the ratio that part by weight is 1: 1.5-2.5 of batch mixing and 70% ethanol, Impregnating 24 hours under the conditions of 25 DEG C, carry out percolation with 70% ethanol by percolation the most again, collection obtains Percolate is standby；
Step 102: according to weight portion weighing polyvinyl alcohol, according to polyvinyl alcohol and the weight of 85% ethanol Ratio be 1: 3-5 ratio add 85% ethanol, under the conditions of 25 DEG C soak 12 hours, take out, dry, Obtain mixture, then according to mixture and the ratio that part by weight is 1: 1-3 of water, in mixture Add water and be heated to dissolving, stir, obtain substrate；
Step 103: take glycerol, azone, Camphora and Mentholum according to weight portion, be then added into State the eutectic mixture that in gained substrate, co-ground is formed, stir, more above-mentioned gained is oozed Liquid of filtering is stirring while adding to be joined in the middle of eutectic mixture, is adding water to amount of preparation, is stirring, Filter, subpackage, obtain described muscles and bones film.
Further, the component of above-mentioned muscles and bones film includes according to weight portion:
The Rhizoma Corydalis of 20 parts-30 parts, the Rhizoma Zingiberis of 40 parts-60 parts, the Herba speranskiae tuberculatae of 20 parts-30 parts, 20 part-30 Part Rhizoma Et Radix Notopterygii, the Rhizoma Kaempferiae of 30 parts-50 parts, the Cortex Cinnamomi of 20 parts-30 parts, the Radix Stephaniae Tetrandrae of 20 parts-30 parts, The Radix Et Rhizoma Nardostachyos of 20 parts-40 parts, the Cortex Acanthopancis of 20 parts-30 parts, the Fructus Capsici of 40 parts-60 parts, 20 parts-40 parts Semen Sinapis Albae, the Pericarpium Zanthoxyli of 5 parts-15 parts, the Flos Carthami of 5 parts-15 parts, the Herba Taxilli of 20 parts-40 parts, 20 The Radix Dipsaci of parts-40 parts, the Lignum Sappan of 10 parts-20 parts, the Radix Clematidis of 20 parts-30 parts, 20 parts-30 parts Herba Lycopodii, the Cortex Illicii of 20 parts-30 parts, the Radix Gentianae Macrophyllae of 20 parts-30 parts, the Mentholum of 20 parts-30 parts, The Camphora of 20 parts-30 parts, the polyvinyl alcohol of 50 parts-70 parts, the glycerol of 40 parts-60 parts and 20 part-30 The azone of part.
Illustrate with the most detailed following embodiment.
First, the Rhizoma Corydalis of 25g, the Rhizoma Zingiberis of 50g, the Herba speranskiae tuberculatae of 25g, the Rhizoma Et Radix Notopterygii of 25g, 40g are weighed Rhizoma Kaempferiae, the Cortex Cinnamomi of 25g, the Radix Stephaniae Tetrandrae of 25g, the Radix Et Rhizoma Nardostachyos of 30g, the Cortex Acanthopancis of 25g, 50g peppery Green pepper, the Semen Sinapis Albae of 30g, the Pericarpium Zanthoxyli of 10g, the Flos Carthami of 10g, the Herba Taxilli of 30g, the Radix Dipsaci of 30g, The Lignum Sappan of 15g, the Radix Clematidis of 25g, the Herba Lycopodii of 25g, the Cortex Illicii of 25g and the Radix Gentianae Macrophyllae of 25g, will Above-mentioned medical material is respectively crushed into coarse powder and is mixed to get batch mixing, according to batch mixing and the weight ratio of 70% ethanol Example be 1: 1.5-2.5 ratio be sufficiently mixed, under the conditions of 25 DEG C impregnate 24 hours, use 70% second the most again Alcohol carries out percolation by percolation, and it is standby that collection obtains percolate；
Then, weigh 60g polyvinyl alcohol, be 1: 3-5 according to the part by weight of polyvinyl alcohol and 85% ethanol Ratio add 85% ethanol, under the conditions of 25 DEG C soak 12 hours, take out, dry, obtain mixture, Then according to mixture and the ratio that part by weight is 1: 1-3 of water, adding water in mixture, it is molten to be heated to Solve, stir, obtain substrate；
Finally, weigh and take 50g glycerol, 25g azone, 25g Camphora and 25g Mentholum, then by it Add the eutectic mixture that in above-mentioned gained substrate, co-ground is formed, stir, then by above-mentioned Gained percolate is stirring while adding to be joined in the middle of eutectic mixture, joins 1000ml adding water to, stirs Mix uniformly, filter, subpackage, obtain described muscles and bones film.
It should be appreciated that the application of the present invention is not limited to above-mentioned citing, to ordinary skill For personnel, can be improved according to the above description or convert, all these modifications and variations are all answered Belong to the protection domain of claims of the present invention.

Claims (2)

1. the preparation method of an analgesic bone film, it comprises the following steps:
A, weigh according to weight portion Rhizoma Corydalis, Rhizoma Zingiberis, Herba speranskiae tuberculatae, Rhizoma Et Radix Notopterygii, Rhizoma Kaempferiae, Cortex Cinnamomi, Radix Stephaniae Tetrandrae, Radix Et Rhizoma Nardostachyos, Cortex Acanthopancis, Fructus Capsici, Semen Sinapis Albae, Pericarpium Zanthoxyli, Flos Carthami, Herba Taxilli, Radix Dipsaci, Radix Clematidis, stretch Muscle grass, Radix Gentianae Macrophyllae, Cortex Illicii and Lignum Sappan, be respectively crushed into coarse powder by above-mentioned medical material and be mixed to get batch mixing, It is sufficiently mixed, under the conditions of 25 DEG C according to the ratio that part by weight is 1: 1.5-2.5 of batch mixing and 70% ethanol Impregnating 24 hours, carry out percolation with 70% ethanol by percolation the most again, it is standby that collection obtains percolate；
B, according to weight portion weighing polyvinyl alcohol, according to the part by weight of polyvinyl alcohol and 85% ethanol be The ratio of 1: 3-5 adds 85% ethanol, soaks 12 hours under the conditions of 25 DEG C, takes out, and dries, obtains Mixture, then according to mixture and the ratio that part by weight is 1: 1-3 of water, adds water in mixture It is heated to dissolving, stirs, obtain substrate；
C, take glycerol, azone, Camphora and Mentholum according to weight portion, be then added into above-mentioned gained The eutectic mixture that in substrate, co-ground is formed, stirs, then by above-mentioned gained percolate limit Edged stirring joins in the middle of eutectic mixture, is adding water to amount of preparation, is stirring, and filters, Subpackage, obtains described muscles and bones film.
Preparation method the most according to claim 1, it is characterised in that the component of above-mentioned muscles and bones film Include according to weight portion:
The Rhizoma Corydalis of 20 parts-30 parts, the Rhizoma Zingiberis of 40 parts-60 parts, the Herba speranskiae tuberculatae of 20 parts-30 parts, 20 part-30 Part Rhizoma Et Radix Notopterygii, the Rhizoma Kaempferiae of 30 parts-50 parts, the Cortex Cinnamomi of 20 parts-30 parts, the Radix Stephaniae Tetrandrae of 20 parts-30 parts, The Radix Et Rhizoma Nardostachyos of 20 parts-40 parts, the Cortex Acanthopancis of 20 parts-30 parts, the Fructus Capsici of 40 parts-60 parts, 20 parts-40 parts Semen Sinapis Albae, the Pericarpium Zanthoxyli of 5 parts-15 parts, the Flos Carthami of 5 parts-15 parts, the Herba Taxilli of 20 parts-40 parts, 20 The Radix Dipsaci of parts-40 parts, the Lignum Sappan of 10 parts-20 parts, the Radix Clematidis of 20 parts-30 parts, 20 parts-30 parts Herba Lycopodii, the Cortex Illicii of 20 parts-30 parts, the Radix Gentianae Macrophyllae of 20 parts-30 parts, the Mentholum of 20 parts-30 parts, The Camphora of 20 parts-30 parts, the polyvinyl alcohol of 50 parts-70 parts, the glycerol of 40 parts-60 parts and 20 part-30 The azone of part.
CN201610223433.2A 2016-03-31 2016-03-31 Preparation method of muscle and bone membrane Pending CN105833217A (en)

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CN106853242A (en) * 2017-03-09 2017-06-16 李卫红 A kind of externally applied drug for treating lumbar vertebra disease, cervical spondylopathy
CN110243981A (en) * 2019-06-25 2019-09-17 湖南中医药大学 A kind of detection reagent and detection method of anthraquinone analog compound

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106853242A (en) * 2017-03-09 2017-06-16 李卫红 A kind of externally applied drug for treating lumbar vertebra disease, cervical spondylopathy
CN110243981A (en) * 2019-06-25 2019-09-17 湖南中医药大学 A kind of detection reagent and detection method of anthraquinone analog compound

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