CN105833080A - Traditional Chinese medicine composition for treating diabetes - Google Patents

Traditional Chinese medicine composition for treating diabetes Download PDF

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Publication number
CN105833080A
CN105833080A CN201610292015.9A CN201610292015A CN105833080A CN 105833080 A CN105833080 A CN 105833080A CN 201610292015 A CN201610292015 A CN 201610292015A CN 105833080 A CN105833080 A CN 105833080A
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parts
radix
diabetes
chinese medicine
treating diabetes
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张蛟
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Chengdu Yishengke Biotechnology Co Ltd
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Chengdu Yishengke Biotechnology Co Ltd
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964—Anemarrhena
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a traditional Chinese medicine composition for treating diabetes .The traditional Chinese medicine composition is mainly prepared from, by weight, 350-380 parts of plaster stone, 270-290 parts of radix scutellariae, 270-290 parts of cortex lycii radicis, 290-190 parts of raw licorice roots, 550-560 parts of radix asparagi, 270-290 parts of radix ophiopogonis, 180-190 parts of radix trichosanthis, 180-190 parts of rhizoma anemarrhenae and 180-190 parts of polished round-grained rice .The traditional Chinese medicine composition has the good effect of treating the diabetes, is basically free of adverse reaction and is suitable for long-term taking of diabetes patients .

Description

A kind of Chinese prescription for treating diabetes
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of Chinese prescription for treating diabetes.
Background technology
Diabetes are a kind of commonly encountered diseases, along with economic development, and the change of the living environment such as industrial pollution, onset diabetes rate Increase very fast, and there is rejuvenation trend.Diabetes divide type i diabetes and type ii diabetes.Type i diabetes is multiple is born in green grass or young crops Teenager, clinical manifestation is hypoinsulinism, and body has to rely on exogenous insulin existence.Type ii diabetes is more common in In, old people, clinical manifestation be body to insulin insensitivity, the secretory volume of insulin is the lowest, the most higher, i.e. insulin supports Anti-(IR).In diabetes loyalty person, the ratio shared by type ii diabetes is about 95%.If type ii diabetes loyalty person's glycemic control Bad, blood capillary that diabetes are brought and macrovascular complications, cardiovascular disease secondary, dyslipidemia, blind, kidney will be caused Nonfunction and amputation etc., the health and lives of serious harm people.
The medicine for the treatment of type ii diabetes is divided into biology, chemical drugs and Chinese medicine at present, and biological medicament is insulin, chemical drugs master Will be based on sulfonylureas, biguanide drug, DPPIV, voglibose, row ketone etc., Chinese medicine is main with diabetes pill etc. Represent.Though chemical drugs class Western medicine blood sugar reducing function is obvious, but long-term taking easily occurs as in hypoglycemia, hepatorenal damage, lactate acid Poison, gastrointestinal tract are anti-, lesions of liver and kidney, increase the weight of cardiovascular complication etc..
TCM Treatment of Diabetes is with a long history, discusses a lot in Chinese medicine document, sporadically appear in " quenching one's thirst ", " eliminating mass ", The disease such as " profit yearningly ", " three disappear ".In more than 2000 year Christian era front Huangdi's Internal Classics the most on the books, in long-term medical practice In, the traditional Chinese medical science have accumulated the abundant experience preventing and treating diabetes and complication thereof.TCM treatment of diabetes focuses on entirety regulation and control, blood sugar lowering Action temperature and, stable, the preventing and treating to chronic complicating diseases of diabetes is evident in efficacy.Do not think to drink to eliminating xerostomia, fatigue and weak, weak The diabetic symptoms such as hyperhidrosis have good efficacy；Toxic and side effects is little, treating both the principal and secondary aspects of a disease, improve body.Chinese patent medicine lacks medicine Imitate significant modern Chinese medicine, still can not meet the needs of the diabetes loyalty person of clinical application.
Summary of the invention
The present invention relates to a kind of Chinese prescription for treating diabetes, a kind of medicine one treating diabetes For treating the Chinese prescription of diabetes.This kind of Chinese prescription for treating diabetes has a supplementing QI and nourishing YIN, promoting the production of body fluid to quench thirst, It is applicable to treating diabetes, improves fatigue and weakness, the diseases such as xerostomia tongue is made an uproar, excessive thirst polydipsia.
The present invention is achieved through the following technical solutions: a kind of Chinese prescription for treating diabetes, mainly by following heavy The raw material of Chinese medicine composition of amount part: Gypsum Fibrosum 350-380 part, Radix Scutellariae 270-290 part, Cortex Lycii 270-290 part, Radix Glycyrrhizae 180- 190 parts, Radix Asparagi 550-560 part, Radix Ophiopogonis 270-290 part, Radix Trichosanthis 180-190 part, Rhizoma Anemarrhenae 180-190 part and Semen oryzae sativae 180- 190 parts.
To better implement the present invention, further, mainly it is made up of the raw material of Chinese medicine of following weight portion: Gypsum Fibrosum 370 Part, Radix Scutellariae 278 parts, Cortex Lycii 278 parts, Radix Glycyrrhizae 185 parts, Radix Asparagi 556 parts, Radix Ophiopogonis 278 parts, Radix Trichosanthis 185 parts, the Rhizoma Anemarrhenae 185 parts and Semen oryzae sativae 185 parts.
To better implement the present invention, further, mainly it is made up of the raw material of Chinese medicine of following weight: Gypsum Fibrosum 370g, Radix Scutellariae 278g, Cortex Lycii 278g, Radix Glycyrrhizae 185g, Radix Asparagi 556g, Radix Ophiopogonis 278g, Radix Trichosanthis 185g, Rhizoma Anemarrhenae 185g and round-grained rice Rice 185g.
To better implement the present invention, further, its dosage form is oral liquid, granule, tablet, capsule, pill Or powder.
To better implement the present invention, further, its dosage form is granule.
The preparation method of the above-mentioned Chinese prescription for treating diabetes, the dosage form of this prescription described is granule, Its method comprises the following steps:
1) Gypsum Fibrosum of weight portion, Radix Trichosanthis, Radix Asparagi, Radix Scutellariae, Radix Glycyrrhizae, Cortex Lycii, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Semen oryzae sativae are cleaned, Join in multi-function extractor and decoct three times, filter, merging filtrate；
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum；
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, the soak by water 1 that second time adds 8 times amount is little Time, third time adds the soak by water 1 hour of 6 times amount.
The present invention compared with prior art, has the following advantages and beneficial effect:
The Chinese prescription of the present invention, treats diabetes excellent effect, substantially has no adverse reaction, and applicable diabetics takes for a long time With.
Detailed description of the invention
The present invention is expanded on further below in conjunction with specific embodiment, it should be appreciated that embodiment be merely to illustrate the present invention and not For limiting the scope of the invention.
Embodiment 1:
For treating the Chinese prescription of diabetes, mainly it is made up of the raw material of Chinese medicine of following weight: Gypsum Fibrosum 370g, Radix Scutellariae 278g, Cortex Lycii 278g, Radix Glycyrrhizae 185g, Radix Asparagi 556g, Radix Ophiopogonis 278g, Radix Trichosanthis 185g, Rhizoma Anemarrhenae 185g and Semen oryzae sativae 185g。
The preparation method of the above-mentioned Chinese prescription for treating diabetes, the dosage form of this prescription described is granule, Its method comprises the following steps:
1) Gypsum Fibrosum of weight portion, Radix Trichosanthis, Radix Asparagi, Radix Scutellariae, Radix Glycyrrhizae, Cortex Lycii, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Semen oryzae sativae are cleaned, Join in multi-function extractor and decoct three times, filter, merging filtrate；
2) filtrate of upper step is heated the thick paste that relative density when being concentrated into 60 DEG C is 1.27-1.33 and obtains extractum；
3) extractum and pharmaceutic adjuvant are mixed and made into oral liquid, granule, capsule, pill or powder.
Wherein, decocting the soak by water that includes for three times adding for the first time 10 times amount 2 hours, the soak by water 1 that second time adds 8 times amount is little Time, third time adds the soak by water 1 hour of 6 times amount.
By step 2) extractum and adjuvant dextrin press the weight ratio mix and blend of 1:2, pelletize, granulate, prepare granule, loading Dress, prepares granule.Every bag of 3g Han extractum.
Embodiment 2:
Enter test diabetics: totally 90 example, wherein, male 66 examples, female 24 example, at minimum 40 years old of age, maximum 70 years old, build was fertile Fat 30 examples, medium 18 examples of build, build becomes thin 32 examples, and the course of disease is the longest 8 years, the shortest June, fasting glucose > 28.1mmol/L 5 example, Fasting glucose > 18.0mmol/L 6 example, fasting glucose > 10.1mmol/L 30 example, fasting glucose > 7.5mmol/L 49 example, glucose in urine (+++) 10 example, glucose in urine (++) 15 example, glucose in urine (+) 20 examples, glucose in urine (-) 35 examples, complicated hypertension, 40 examples of hyperlipidemia, clinical table Now for polydipsia, polyphagia, 43 examples of becoming thin, show as polydipsia, polyuria, weak, poor appetite substantially do not become thin person 20 example, show as polydipsia, many Urine, polyphagia are without 47 examples become thin.
Take diabetes pill therapist 23 example before test, take 20 examples of diabetes pill, Or Metformin In Treating, use insulin every day 2 examples of twice.
Medication:
Patient disables all hypoglycemic medicines taken before this, then the granule by warm boiled water embodiment 2, each takes 3g, three times a day, 20 days was 1 course for the treatment of.
Curative effect judging standard:
Cure: clinical symptoms polydipsia, polyphagia, polyuria disappear, chemical examination fasting glucose less than 6.3mmol/L, glucose in urine (-)；
Effective: clinical symptoms, sign disappear, chemical examination fasting glucose < 7.0mmol/L, glucose in urine (-)；
Effective: clinical symptoms, sign take a turn for the better, fasting glucose < 8.5mmol/L, glucose in urine (-)；
Invalid: fasting glucose be more than 12mmol/L, glucose in urine > (+) or treatment after blood glucose raise.
Result of the test:
Curing 60 examples and account for 66.7%, effective 27 examples account for 30%, and effective 2 examples account for 2.2%, and invalid 1 example accounts for 1.1%,
Untoward reaction: feel stomach discomfort after few patients's medication, substantially without other side reaction, particularly go out without hypoglycemic effect Existing.
Through above-mentioned experiment, the Chinese medicine composition of the present invention, treat diabetes excellent effect, substantially have no adverse reaction, suitable Use diabetics long-term taking.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not Depart from and these embodiments can be carried out multiple change under the principle of the present invention and objective, revise, replace and modification, the present invention's Scope is limited by claim and equivalent thereof.

Claims (5)

1. the Chinese prescription being used for treating diabetes, it is characterised in that be mainly made up of the raw material of Chinese medicine of following weight portion: Gypsum Fibrosum 350-380 part, Radix Scutellariae 270-290 part, Cortex Lycii 270-290 part, Radix Glycyrrhizae 180-190 part, Radix Asparagi 550-560 Part, Radix Ophiopogonis 270-290 part, Radix Trichosanthis 180-190 part, Rhizoma Anemarrhenae 180-190 part and Semen oryzae sativae 180-190 part.
A kind of Chinese prescription for treating diabetes the most according to claim 1, it is characterised in that main by following heavy Amount part raw material of Chinese medicine composition: Gypsum Fibrosum 370 parts, Radix Scutellariae 278 parts, Cortex Lycii 278 parts, Radix Glycyrrhizae 185 parts, Radix Asparagi 556 parts, Radix Ophiopogonis 278 parts, Radix Trichosanthis 185 parts, the Rhizoma Anemarrhenae 185 parts and Semen oryzae sativae 185 parts.
A kind of Chinese prescription for treating diabetes the most according to claim 2, it is characterised in that main by following heavy The raw material of Chinese medicine composition of amount: Gypsum Fibrosum 370g, Radix Scutellariae 278g, Cortex Lycii 278g, Radix Glycyrrhizae 185g, Radix Asparagi 556g, Radix Ophiopogonis 278g, Radix Trichosanthis 185g, Rhizoma Anemarrhenae 185g and Semen oryzae sativae 185g.
4. according to the arbitrary described a kind of Chinese prescription for treating diabetes of claim 1-3, it is characterised in that its preparation Form is oral liquid, granule, tablet, capsule, pill or powder.
A kind of Chinese prescription for treating diabetes the most according to claim 4, it is characterised in that its dosage form is Granule.
CN201610292015.9A 2016-05-05 2016-05-05 Traditional Chinese medicine composition for treating diabetes Withdrawn CN105833080A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653642A (en) * 2018-07-09 2018-10-16 张春枝 Treat the drug and preparation method thereof of diabetes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653642A (en) * 2018-07-09 2018-10-16 张春枝 Treat the drug and preparation method thereof of diabetes

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