CN105833047A - Preparation method of dendrobium nobile and American ginseng granules - Google Patents

Preparation method of dendrobium nobile and American ginseng granules Download PDF

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CN105833047A
CN105833047A CN201610429068.0A CN201610429068A CN105833047A CN 105833047 A CN105833047 A CN 105833047A CN 201610429068 A CN201610429068 A CN 201610429068A CN 105833047 A CN105833047 A CN 105833047A
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dendrobium nobile
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radix panacis
panacis quinquefolii
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杨继勇
廖晓康
廖方华
邓贤芬
亢俊峰
赵克琼
张芳
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CHISHUI TRUSKY TRADITIONAL CHINESE MEDICINE INDUSTRY DEVELOPMENT Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K9/1629Organic macromolecular compounds
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    • A61K2236/30Extraction of the material
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    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a preparation method of dendrobium nobile and American ginseng granules. The method comprises the following steps of a, taking dendrobium nobile and American ginseng, and crushing to obtain dendrobium nobile and American ginseng superfine powder; b, taking the dendrobium nobile superfine powder, adding 35 to 55 times of water, performing ultrasonic extraction under the condition that the temperature is 55 to 75DEG C and the power is 130 to 270W for two times, keeping for 65 to 78 minutes each time, then centrifuging, taking supernate, concentrating and drying the supernate to obtain dendrobium nobile extract, and crushing to obtain dendrobium nobile extract powder, namely a product B; c, taking American ginseng superfine powder, adding 70 percent of ethanol, adding 22 to 38ml of 70 percent ethanol according to 1g of American ginseng superfine powder, performing ultrasonic extraction under the condition that the temperature is 52 to 67DEG C and the power is 130 to 270W for two times, keeping for 35 to 55 minutes each time, the centrifuging, taking supernate, concentrating and drying the supernate to obtain American ginseng extract, and crushing to obtain American ginseng extract powder, namely a product C; d, mixing the product B with the product C according to the proportion of 2.4:1 to obtain a product D. The granules prepared by the preparation method disclosed by the invention have good effect for enhancing immunity.

Description

A kind of preparation method of Dendrobium nobile american ginseng granules
Technical field
The present invention relates to the preparation method of a kind of Dendrobium nobile Radix Panacis Quinquefolii, the Dendrobium nobile of a kind of enhancing immunity The preparation method of american ginseng granules.
Background technology
Immunity refers to that human immune system resists the ability of pathogenic infection.Immune system is by thymus (after adolescence The most gradually atrophy, degeneration), the composition such as spleen and lymphoid tissue.One sound human immune system is the defence that body is main System, can protect body to be without prejudice, and helps body to eliminate external antibacterial, virus, repairs organ in damaged condition and tissue It is made to recover original function etc..And everyone immunity is different, the people that immunity is strong is difficult to sick, and immunity is weak People easily induced various disease by pathogenic bacterial infection.Immunoglobulin is to be produced by immune system, and the power of immunity takes Certainly in quantity and the vigor of its globulin, immunoglobulin is that domestic and international scientific circles generally acknowledge and are the raisings being widely used The material of human disease resistance.0~12 years old front immunization programs for children allelotaxis's imperfection, the internal immune ball having antibody activity Protein secretion is few, and immunologic function is unsound, and child at this moment is as easy as rolling off a log sick.13~be that immunologic function is the most steady during 45 years old Periodically, immunologic function comparatively perfect.But owing to the people in this stage is easily subject to the pressure influence living, learn, work, make Internal antibody and somatomedin secretory volume fluctuate widely, and this to will result in internal immunoglobulin content unstable, Cause immunity degradation and sick.After 46 years old, the immune organ function of human body falls into a decline, the internal immunity having antibody activity Globulin and somatomedin secretion decline, immunity degradation;Start to induce Senile disease.Investigate according to World Health Organization (WHO), entirely Ball there are about the people of more than 35% and is in fatigue state, and especially middle-aged male crowd fatigue state person is up to 60-75%.Expert refers to Going out, extended sleep is the best, continue fatigue easily causes chronic pharyngolaryngitis, cervical region or axillary gland to swell and ache, muscular soreness And the disease such as multiple diarthrodial joint pain, ultimately result in immunity degradation, and after immunity degradation, make again " tired Syndrome " more prominent and deterioration, thus form a vicious cycle.Along with the development of society, the progress of science and technology, rhythm of life Quickening, culture and material life abundant, not only middle age is in the fatigue state of subhealth state, and each big-and-middle college students is the most all There is fatigue phenomenon.
Dendrobium nobile is the rare Chinese medicine that China is traditional, is classified as top grade in " Sheng Nong's herbal classic ".Modern medicine and the traditional Chinese medical science Pharmacological research shows, Herba Dendrobii has significantly at aspects such as improving human body immunity, defying age, suppression tumor, tonifying five ZANG-organs asthenia Effect.The title having " help Herba mesonae chinensis " among the people.It is commonly called as medicine gold, cold in nature, sweet in the mouth, light, micro-salty.Being born on cliff, stem is grown thickly.Health care Function: nourishing YIN and moistening the lung, stomach reinforcing the kidney invigorating, build brain improving eyesight, pathogenic fire reducing good medicine, and have promoting the production of body fluid to quench thirst, tonifying five ZANG-organs asthenia, clearing away lung-heat to relieve cough, anti- Flu, effect of resisting fatigue.Radix Panacis Quinquefolii, as qi-tonifying health-care first-selection medical material, can promote that serum albumin synthesis, bone marrow protein close One-tenth, organ protein's synthesis etc., improve immunity of organisms, and anticancer grows, and is effective against cancer.And Dendrobium nobile effectively becomes The extraction comparison divided is complicated, and extraction ratio is relatively low;Dendrobium nobile can fully be extracted with the effective ingredient of Radix Panacis Quinquefolii and ties mutually Close and just seem more difficult;So studying the system of the effective Dendrobium nobile american ginseng granules of a kind of enhancing body autoimmunity Preparation Method has extensively profound significance.
Summary of the invention
The purpose of the present invention, is to provide the preparation method of a kind of Dendrobium nobile american ginseng granules.The present invention can effectively by The effective ingredient of Dendrobium nobile and Radix Panacis Quinquefolii fully extracts and combines, and extracting method is simple;Extraction ratio is high;Prepare Granule effective to enhancing immunity.
The present invention is realized in.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method includes following step Rapid:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 35-55 times amount, temperature be 55-75 DEG C, under conditions of power is 130-270W Ultrasonic extraction 2 times, each 65-78min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain Dendrobium nobile leaching Cream, pulverizes and obtains dendrobium nobile extractum powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 22-38ml by every 1g Radix Panacis Quinquefolii superfine powder, in temperature be 52-67 DEG C, power be ultrasonic extraction 2 times, each 35-55min under conditions of 130-270W, then be centrifuged, take supernatant, Supernatant concentration is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.3-2.2g dextrin, add the A Si of 60% ethanol 0.2-0.8ml and 0.05-0.15g Ba Tian mixes, and crosses 14 mesh sieve granulate, to obtain final product.
More optimizedly, in the preparation method of aforesaid Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 40-50 times amount, temperature be 60-70 DEG C, under conditions of power is 150-250W Ultrasonic extraction 2 times, each 68-75min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain Dendrobium nobile leaching Cream, pulverizes and obtains dendrobium nobile extractum powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 25-35ml by every 1g Radix Panacis Quinquefolii superfine powder, in temperature be 55-65 DEG C, power be ultrasonic extraction 2 times, each 40-50min under conditions of 150-250W, then be centrifuged, take supernatant, Supernatant concentration is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.5-2g dextrin, add the A Siba of 60% ethanol 0.3-0.7ml and 0.08-0.12g Sweet mixing, crosses 14 mesh sieve granulate, to obtain final product.
Optimum, in the preparation method of aforesaid Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 45 times amount, temperature be 65 DEG C, power be 200W under conditions of ultrasonic extraction 2 Secondary, each 72min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 30ml by every 1g Radix Panacis Quinquefolii superfine powder, be 60 in temperature DEG C, power be ultrasonic extraction 2 times, each 45min under conditions of 200W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.8g dextrin, add 60% ethanol 0.5ml and 0.1g aspartame mixing, cross 14 mesh Sieve granulate, to obtain final product.
Compared with the prior art, the preparation method of Dendrobium nobile american ginseng granules of the present invention.Wherein Dendrobium nobile Cold nature, sweet in the mouth, return stomach, kidney channel, have except the spleen therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia, reinforcing YIN-essence grow smart effect, hinder for calentura Tianjin, mouth Dry excessive thirst, deficiency of stomach-Yin, lack of appetite nausea;The diseases such as deficiency-heat is not moved back after being ill, hyperactivity of fire caused by deficiency of YIN, steaming bone and consumptive fever, poor vision, flaccidity of extremities Disease.Radix Panacis Quinquefolii is cool in nature, sweet in the mouth, micro-hardship;GUIXIN, lung, kidney, have boosting qi and nourishing yin, effect of clearing away heat and promoting production of body fluid, is usually used in the deficiency of vital energy cloudy Lose, the diseases such as deficiency-heat is tired of tired, and cough with asthma expectorant blood interior-heat is quenched one's thirst, dryness of the mouth and throat.With Dendrobium nobile reinforcing stomach reg fluid, nourishing YIN and clearing away heat as monarch Medicine;Radix Panacis Quinquefolii boosting qi and nourishing yin, clearing away heat and promoting production of body fluid, helping Herba Dendrobii clearing away heat and promoting production of body fluid is ministerial drug;Raw material adds a certain amount of liquid, special Under conditions of the present invention utilize ultrasound wave that liquid is extracted, the solution obtained takes supernatant again, the working substance in supernatant Matter content is maximum, utilizes supernatant to carry out follow-up processing again;Accordingly, it is capable to having Dendrobium nobile and Radix Panacis Quinquefolii effectively Effect composition fully extracts and combines, and extracting method is simple;Extraction ratio is high;The granule prepared is to enhancing immunity effect Good.
Detailed description of the invention
Embodiment 1.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, be utilized respectively super micron mill and pulverize and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii ultra micro Powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 45 times amount, temperature be 65 DEG C, power be 200W under conditions of ultrasonic extraction 2 Secondary, each 72min, recycling centrifuge is centrifuged, and takes supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, Pulverize with pulverizer and obtain dendrobium nobile extractum powder;I.e. B product;Described pulverizer is conventional grinder;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 30ml by every 1g Radix Panacis Quinquefolii superfine powder, be 60 in temperature DEG C, power be ultrasonic extraction 2 times under conditions of 200W, each 45min, recycling centrifuge is centrifuged, and takes supernatant, will Supernatant concentration is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes with pulverizer and obtains American ginseng extract powder;I.e. C product;Described pulverizer For conventional grinder;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.8g dextrin, add 60% ethanol 0.5ml and 0.1g aspartame mixing, cross 14 mesh Sieve granulate, to obtain final product.
Embodiment 2.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 35 times amount, temperature be 55 DEG C, power be 130W under conditions of ultrasonic extraction 2 Secondary, each 65min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 22ml by every 1g Radix Panacis Quinquefolii superfine powder, be 52 in temperature DEG C, power be ultrasonic extraction 2 times, each 35min under conditions of 130W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.3g dextrin, add 60% ethanol 0.2ml and 0.05g aspartame mixing, cross 14 Mesh sieve granulate, to obtain final product.
Embodiment 3.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 55 times amount, temperature be 75 DEG C, power be 270W under conditions of ultrasonic extraction 2 Secondary, each 78min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 38ml by every 1g Radix Panacis Quinquefolii superfine powder, be 67 in temperature DEG C, power be ultrasonic extraction 2 times, each 55min under conditions of 270W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 2.2g dextrin, add 60% ethanol 0.8ml and 0.15g aspartame mixing, cross 14 Mesh sieve granulate, to obtain final product.
Embodiment 4.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 40 times amount, temperature be 60 DEG C, power be 150W under conditions of ultrasonic extraction 2 Secondary, each 68min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 25ml by every 1g Radix Panacis Quinquefolii superfine powder, be 55 in temperature DEG C, power be ultrasonic extraction 2 times, each 40min under conditions of 150W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.5g dextrin, add 60% ethanol 0.3ml and 0.08g aspartame mixing, cross 14 Mesh sieve granulate, to obtain final product.
Embodiment 5.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 50 times amount, temperature be 70 DEG C, power be 250W under conditions of ultrasonic extraction 2 Secondary, each 75min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 35ml by every 1g Radix Panacis Quinquefolii superfine powder, be 65 in temperature DEG C, power be ultrasonic extraction 2 times, each 50min under conditions of 250W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 2g dextrin, add 60% ethanol 0.7ml and 0.12g aspartame mixing, cross 14 mesh Sieve granulate, to obtain final product.
Embodiment 5.The preparation method of a kind of Dendrobium nobile american ginseng granules, the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 43 times amount, temperature be 68 DEG C, power be 220W under conditions of ultrasonic extraction 2 Secondary, each 70min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 32ml by every 1g Radix Panacis Quinquefolii superfine powder, be 62 in temperature DEG C, power be ultrasonic extraction 2 times, each 43min under conditions of 180W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product after mixing;
E, by every 1g D product add 1.7g dextrin, add 60% ethanol 0.6ml and 0.09g aspartame mixing, cross 14 Mesh sieve granulate, to obtain final product.

Claims (3)

1. the preparation method of a Dendrobium nobile american ginseng granules, it is characterised in that: the method comprises the steps:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 35-55 times amount, temperature be 55-75 DEG C, under conditions of power is 130-270W Ultrasonic extraction 2 times, each 65-78min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain Dendrobium nobile leaching Cream, pulverizes and obtains dendrobium nobile extractum powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 22-38ml by every 1g Radix Panacis Quinquefolii superfine powder, in temperature be 52-67 DEG C, power be ultrasonic extraction 2 times, each 35-55min under conditions of 130-270W, then be centrifuged, take supernatant, Supernatant concentration is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product;
E, by every 1g D product add 1.3-2.2g dextrin, add the A Si of 60% ethanol 0.2-0.8ml and 0.05-0.15g Ba Tian mixes, and crosses 14 mesh sieve granulate, to obtain final product.
2. the preparation method of Dendrobium nobile american ginseng granules as claimed in claim 1, it is characterised in that: the method includes following Step:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 40-50 times amount, temperature be 60-70 DEG C, under conditions of power is 150-250W Ultrasonic extraction 2 times, each 68-75min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain Dendrobium nobile leaching Cream, pulverizes and obtains dendrobium nobile extractum powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 25-35ml by every 1g Radix Panacis Quinquefolii superfine powder, in temperature be 55-65 DEG C, power be ultrasonic extraction 2 times, each 40-50min under conditions of 150-250W, then be centrifuged, take supernatant, Supernatant concentration is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product;
E, by every 1g D product add 1.5-2g dextrin, add the A Siba of 60% ethanol 0.3-0.7ml and 0.08-0.12g Sweet mixing, crosses 14 mesh sieve granulate, to obtain final product.
3. the preparation method of Dendrobium nobile american ginseng granules as claimed in claim 2, it is characterised in that: the method includes following Step:
A, take Dendrobium nobile and Radix Panacis Quinquefolii, pulverize respectively and obtain Dendrobium nobile superfine powder and Radix Panacis Quinquefolii superfine powder, standby;
B, depletion hairpin dendrobe ultrafine powder add the water of 45 times amount, temperature be 65 DEG C, power be 200W under conditions of ultrasonic extraction 2 Secondary, each 72min, then be centrifuged, take supernatant, supernatant concentration is dried to obtain dendrobium nobile extractum, pulverize and obtain gold Hairpin Herba Dendrobii extract powder;I.e. B product;
C, take Radix Panacis Quinquefolii superfine powder and add 70% ethanol, add 70% ethanol 30ml by every 1g Radix Panacis Quinquefolii superfine powder, be 60 in temperature DEG C, power be ultrasonic extraction 2 times, each 45min under conditions of 200W, then be centrifuged, take supernatant, by supernatant concentration It is dried to obtain Radix Panacis Quinquefolii extractum, pulverizes and obtain American ginseng extract powder;I.e. C product;
D, by B product: C product be 2.4:1 mixing, obtain D product;
E, by every 1g D product add 1.8g dextrin, add 60% ethanol 0.5ml and 0.1g aspartame mixing, cross 14 mesh Sieve granulate, to obtain final product.
CN201610429068.0A 2016-06-17 2016-06-17 Preparation method of dendrobium nobile and American ginseng granules Pending CN105833047A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101305801A (en) * 2008-06-17 2008-11-19 陶国闻 Dendrobium nobile American ginseng capsule
CN101757453A (en) * 2010-03-03 2010-06-30 澳诺(中国)制药有限公司 American ginseng-glossy ganoderma-dendrobe preparation and preparation method thereof
CN102907670A (en) * 2012-10-22 2013-02-06 广西壮族自治区农业科学院农产品加工研究所 Compound dendrobium candidum and American ginseng buccal tablets and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101305801A (en) * 2008-06-17 2008-11-19 陶国闻 Dendrobium nobile American ginseng capsule
CN101757453A (en) * 2010-03-03 2010-06-30 澳诺(中国)制药有限公司 American ginseng-glossy ganoderma-dendrobe preparation and preparation method thereof
CN102907670A (en) * 2012-10-22 2013-02-06 广西壮族自治区农业科学院农产品加工研究所 Compound dendrobium candidum and American ginseng buccal tablets and preparation method thereof

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