CN105796833A - Traditional Chinese medicine lotion for treating fracture swelling - Google Patents

Traditional Chinese medicine lotion for treating fracture swelling Download PDF

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CN105796833A
CN105796833A CN201610290644.8A CN201610290644A CN105796833A CN 105796833 A CN105796833 A CN 105796833A CN 201610290644 A CN201610290644 A CN 201610290644A CN 105796833 A CN105796833 A CN 105796833A
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herba
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caulis
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刘毅
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/41—Crassulaceae (Stonecrop family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

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Abstract

The invention discloses a traditional Chinese medicine lotion for treating fracture swelling, belonging to the technical field of traditional Chinese medicine. Based on the pathogenesis of fracture swelling, the inventor selects the traditional Chinese medicines with functions of activating blood and resolving stasis, tonifying middle and replenishing qi and dispersing wind and diminishing swelling, including nephrolepis auriculata, elaegnus henryi, stem and leaf of hookedhairypod tickclover, herba kulanchoes laciniatae, caudate tickclover root, multiflora rose root, manyflower jasmine herb or flower, humulus japonicus, herba euonymi 1, hancock swallowwort herb, smilax riparia, limonium aureum and croton laevigatus vahl to prepare the lotion; according to clinical trials, the curative effect is relatively good.

Description

A kind of external washout with traditional Chinese herbs agent treating fracture swelling
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of external washout with traditional Chinese herbs agent treating fracture swelling.
Background technology
Swelling is fracture early stage and the common clinical manifestation of fracture surgery, and it is improve fracture clinical efficacy that early stage eliminates postoperative limb swelling as early as possible, reduces the important step of post-operative complication.Development along with industry and Modern Traffic, the order of severity of fracture and injury and frequency are also increasing, in the treatment of extremity fracture and Soft tissue injury, suffering limb has swelling in various degree, and severe patient affects venous return, even affect the blood supply of suffering limb, patient is pain because of swelling, and limbs are uncomfortable, increases psychological burden, have a strong impact on quality of life and therapeutic effect, affect union of fracture.Tradition doctor trained in Western medicine, physical method therapeutic effect are not good, and swelling is disappeared relatively slow, is also easily generated side effect.Therefore, the present inventor is little from toxic and side effects, and resourceful Chinese herbal medicine is started with, through clinical practice for many years, according to theory of Chinese medical science, dialectical treat, according to the cause of disease, suit the remedy to the case, developing a kind of external washout with traditional Chinese herbs agent treating fracture swelling, through clinical trial, curative effect is better.
Summary of the invention
It is an object of the invention to provide a kind of external washout with traditional Chinese herbs agent treating fracture swelling.Theory of Chinese medical science thinks that the wet stasis of blood of the deficiency of vital energy is the main pathology of fracture surgery swelling, and swelling is weakened body resistance after belonging to wound, and blood oozing from the body openings or subcuta neous tissue is in outward, and yang-energy is impaired, and QI and blood circumfluence is not smooth, caused by QI and blood alluvial.The spleen being the foundation of acquired constitution, insufficiency of the spleen, diet is not good for, and the source day of nutrition is inadequate, and metabolism is slow, and bones and muscles injury repair ability declines.Therefore treatment should with activating blood circulation to dissipate blood stasis, and invigorating the spleen and replenishing QI, hydrophobic detumescence is main.
It is an object of the invention to be achieved through the following technical solutions, this external washout with traditional Chinese herbs agent is made up of the Chinese medicine of following weight portion: Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 11-17 part, Caulis et Folium Elaeagni Henryi 12-18 part, Caulis et Folium Desmodii Gangetici 8-14 part, Herba Kalanchoes Laciniatae 7-13 part, Radix Desmodii Caudati 6-12 part, Radix rosae multiflorae 14-20 part, Herba jasmini polyanthi 13-20 part, grass 11-17 part, Caulis Seu Folium Euonymi Fortunei 11-19 part, Herba Cynanchi Hancockiani 9-15 part, Radix et Rhizoma Smilacis Ripariae 8-14 part, Flos Limonii Aurei 11-17 part, Radix seu Folium Crotonis Laevigati 11-19 part.
Preferred: Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 14 parts, Caulis et Folium Elaeagni Henryi 15 parts, Caulis et Folium Desmodii Gangetici 11 parts, Herba Kalanchoes Laciniatae 10 parts, Radix Desmodii Caudati 9 parts, Radix rosae multiflorae 17 parts, Herba jasmini polyanthi 17 parts, grass 14 parts, Caulis Seu Folium Euonymi Fortunei 15 parts, Herba Cynanchi Hancockiani 12 parts, Radix et Rhizoma Smilacis Ripariae 11 parts, Flos Limonii Aurei 14 parts, Radix seu Folium Crotonis Laevigati 15 parts.
Preparation method: traditionally make outer lotion.
Fang Zhong: Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating；Caulis et Folium Elaeagni Henryi fracture-setting powder is long-pending, reducing swelling and alleviating pain；Caulis et Folium Desmodii Gangetici hemostasis and pain-relieving, blood stasis slaking and dissipating edema；Herba Kalanchoes Laciniatae heat-clearing and toxic substances removing, dissipating blood stasis stop blooding；Radix Desmodii Caudati expelling wind and removing dampness, promoting blood circulation and detoxication；Radix rosae multiflorae clearing away heat-damp and promoting diuresis, expelling wind and activating blood circulation, removing toxic substances；Herba jasmini polyanthi heat clearing and inflammation relieving, blood-activating and qi-promoting, pain relieving；Grass clearing away heat and promoting diuresis, repercussive removing toxic substances；Caulis Seu Folium Euonymi Fortunei relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis repercussive；Herba Cynanchi Hancockiani promoting blood circulation and stopping pain, antiinflammatory；Radix et Rhizoma Smilacis Ripariae inrigorating qi and promoting blood circulation, channels sootheing and network vessel quickening；Flos Limonii Aurei analgesic antiphlogistic, enrich blood；Radix seu Folium Crotonis Laevigati restores menstrual flow and invigorates blood circulation, dissipating blood stasis for subsidence of swelling, antipyretic analgesic.
Clinical data
1, physical data is in April 2013 February in 2011, and 100 example patients to our hospital are fracture surgery suffering limb swelling, and stochastic averagina is divided into Chinese drug-treated group 50 example and matched group 50 example.Chinese drug-treated group man 38 examples, female 12 example, the mean age (32.5 ± 3.3) year, ankle joint fracture 9 example, Patella fracture 5 example, fracture of tibia and fibula 13 example, fracture of shaft of femur 20 example, supracondylar fracture of the femur 3 example.Manual reduction plaster fixing 26 example, open reduction and Kirschner wire fixation 24 example.Matched group man 30 examples, female 20 example, the mean age (33.1 ± 3.1) year, ankle joint fracture 8 example, Patella fracture 8 example, fracture of tibia and fibula 9 example, fracture of shaft of femur 20 example, supracondylar fracture of the femur 5 example.Manual reduction plaster fixing 25 example, open reduction and Kirschner wire fixation 25 example.Two groups of equal no difference of science of statistics in age, sex ratio, fracture site, operation method etc..
2, swelling degree calibration by with the limbs same area week footpath trade-off of strong side.Slight: with strong side Zhou Jing than < 1.2, moderate: with strong side Zhou Jing ratio between 1.2～1.5, severe: with strong side Zhou Jing ratio between 1.5～1.8, pole severe: with strong side Zhou Jing than > 1.8.Two groups of patient's suffering limb swelling degree: 10 examples that Chinese drug-treated group is slight, moderate 11 example, severe 19 example, pole severe 10 example；11 examples that matched group is slight, moderate 10 example, severe 17 example, pole severe 12 example, two groups of patient's suffering limb swelling degree also no difference of science of statistics.
3, Therapeutic Method Chinese drug-treated group adopts external washout with traditional Chinese herbs of the present invention treatment, weigh Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 14g, Caulis et Folium Elaeagni Henryi 15g, Caulis et Folium Desmodii Gangetici 11g, Herba Kalanchoes Laciniatae 10g, Radix Desmodii Caudati 9g, Radix rosae multiflorae 17g, Herba jasmini polyanthi 17g, grass 14g, Caulis Seu Folium Euonymi Fortunei 15g, Herba Cynanchi Hancockiani 12g, Radix et Rhizoma Smilacis Ripariae 11g, Flos Limonii Aurei 14g, Radix seu Folium Crotonis Laevigati 15g, washout after decocting, every day 3 times, 7 days is a course for the treatment of；Matched group adopts hemostasis and pain-relieving anti-inflammatory treatment 1. Conventional analgesics, antibiotic medicine, has obvious bleeder to give hemorrhage；2. ice bag applies suffering limb.Ice bag towel parcel spreads on suffering limb, each 1 hour, every day 3 times.Two groups of all foot, padded at one's knees, lifting affected limbs 15～25 degree, be beneficial to vein and lymphatic return, and encourage, instruct and suffer from functional exercise.
4, efficacy evaluation disappears: swelling is wholly absent or substantially disappears.Effective: pole severe transfers moderate to, and severe transfers to slightly.Effective: swelling degree one grade of decline, but do not disappear.Invalid: swelling degree is not down or up.In treating latter 7 days, different time points record swelling starts to alleviate number and ratio, treats latter 7 days record therapeutic effect.
5, therapeutic outcome
After two groups of fracture patients are treated 7 days, suffering limb swelling therapeutic effect compares and sees following table.
Group Number of cases Disappear Effective Effectively Invalid
Chinese drug-treated group 50 35 10 5 0
Matched group 50 5 20 10 15
Upper table shows, after two groups of fracture patients are treated 7 days, suffering limb swelling therapeutic effect rank test is compared, data difference statistically significant (P < 0.05), Chinese drug-treated group extinction rate 70%, matched group extinction rate is 10%, data difference statistically significant (P < 0.05).
Detailed description of the invention
Embodiment one: weigh Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 11g, Caulis et Folium Elaeagni Henryi 12g, Caulis et Folium Desmodii Gangetici 8g, Herba Kalanchoes Laciniatae 7g, Radix Desmodii Caudati 6g, Radix rosae multiflorae 14g, Herba jasmini polyanthi 13g, grass 11g, Caulis Seu Folium Euonymi Fortunei 11g, Herba Cynanchi Hancockiani 9g, Radix et Rhizoma Smilacis Ripariae 8g, Flos Limonii Aurei 11g, Radix seu Folium Crotonis Laevigati 11g, traditionally make outer lotion.
Embodiment two: weigh Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 14g, Caulis et Folium Elaeagni Henryi 15g, Caulis et Folium Desmodii Gangetici 11g, Herba Kalanchoes Laciniatae 10g, Radix Desmodii Caudati 9g, Radix rosae multiflorae 17g, Herba jasmini polyanthi 17g, grass 14g, Caulis Seu Folium Euonymi Fortunei 15g, Herba Cynanchi Hancockiani 12g, Radix et Rhizoma Smilacis Ripariae 11g, Flos Limonii Aurei 14g, Radix seu Folium Crotonis Laevigati 15g, traditionally make outer lotion.
Embodiment three: weigh Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 17g, Caulis et Folium Elaeagni Henryi 18g, Caulis et Folium Desmodii Gangetici 14g, Herba Kalanchoes Laciniatae 13g, Radix Desmodii Caudati 12g, Radix rosae multiflorae 20g, Herba jasmini polyanthi 20g, grass 17g, Caulis Seu Folium Euonymi Fortunei 19g, Herba Cynanchi Hancockiani 15g, Radix et Rhizoma Smilacis Ripariae 14g, Flos Limonii Aurei 17g, Radix seu Folium Crotonis Laevigati 19g, traditionally make outer lotion.

Claims (2)

1. the external washout with traditional Chinese herbs agent treating fracture swelling, it is characterised in that this external washout with traditional Chinese herbs agent is made up of the Chinese medicine of following weight portion: Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 11-17 part, Caulis et Folium Elaeagni Henryi 12-18 part, Caulis et Folium Desmodii Gangetici 8-14 part, Herba Kalanchoes Laciniatae 7-13 part, Radix Desmodii Caudati 6-12 part, Radix rosae multiflorae 14-20 part, Herba jasmini polyanthi 13-20 part, grass 11-17 part, Caulis Seu Folium Euonymi Fortunei 11-19 part, Herba Cynanchi Hancockiani 9-15 part, Radix et Rhizoma Smilacis Ripariae 8-14 part, Flos Limonii Aurei 11-17 part, Radix seu Folium Crotonis Laevigati 11-19 part.
2. a kind of external washout with traditional Chinese herbs agent treating fracture swelling as claimed in claim 1, it is characterised in that this external washout with traditional Chinese herbs agent is made up of the Chinese medicine of following weight portion: Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 14 parts, Caulis et Folium Elaeagni Henryi 15 parts, Caulis et Folium Desmodii Gangetici 11 parts, Herba Kalanchoes Laciniatae 10 parts, Radix Desmodii Caudati 9 parts, Radix rosae multiflorae 17 parts, Herba jasmini polyanthi 17 parts, grass 14 parts, Caulis Seu Folium Euonymi Fortunei 15 parts, Herba Cynanchi Hancockiani 12 parts, Radix et Rhizoma Smilacis Ripariae 11 parts, Flos Limonii Aurei 14 parts, Radix seu Folium Crotonis Laevigati 15 parts.
CN201610290644.8A 2016-04-25 2016-04-25 Traditional Chinese medicine lotion for treating fracture swelling Withdrawn CN105796833A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106728489A (en) * 2017-03-21 2017-05-31 宋祥义 A kind of medicine that Sodium Aescinate liniment side effect is reduced in swelling after treating fracture

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104666567A (en) * 2015-02-26 2015-06-03 赵太虹 Traditional Chinese medicine lotion for treating fracture swelling and nursing method
CN105125822A (en) * 2015-09-17 2015-12-09 王铭伦 Traditional Chinese medicine composition for treating postoperative swelling of fracture of lower limb
CN105148019A (en) * 2015-09-27 2015-12-16 南京晶云化工有限公司 Medicinal preparation used for treating fractures

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104666567A (en) * 2015-02-26 2015-06-03 赵太虹 Traditional Chinese medicine lotion for treating fracture swelling and nursing method
CN105125822A (en) * 2015-09-17 2015-12-09 王铭伦 Traditional Chinese medicine composition for treating postoperative swelling of fracture of lower limb
CN105148019A (en) * 2015-09-27 2015-12-16 南京晶云化工有限公司 Medicinal preparation used for treating fractures

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106728489A (en) * 2017-03-21 2017-05-31 宋祥义 A kind of medicine that Sodium Aescinate liniment side effect is reduced in swelling after treating fracture

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