CN105796608A - Compound fullerene healthcare drinking water and preparation method thereof - Google Patents
Compound fullerene healthcare drinking water and preparation method thereof Download PDFInfo
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- CN105796608A CN105796608A CN201610229251.6A CN201610229251A CN105796608A CN 105796608 A CN105796608 A CN 105796608A CN 201610229251 A CN201610229251 A CN 201610229251A CN 105796608 A CN105796608 A CN 105796608A
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- XMWRBQBLMFGWIX-UHFFFAOYSA-N C60 fullerene Chemical compound C12=C3C(C4=C56)=C7C8=C5C5=C9C%10=C6C6=C4C1=C1C4=C6C6=C%10C%10=C9C9=C%11C5=C8C5=C8C7=C3C3=C7C2=C1C1=C2C4=C6C4=C%10C6=C9C9=C%11C5=C5C8=C3C3=C7C1=C1C2=C4C6=C2C9=C5C3=C12 XMWRBQBLMFGWIX-UHFFFAOYSA-N 0.000 title claims abstract description 34
- 229910003472 fullerene Inorganic materials 0.000 title claims abstract description 34
- 150000001875 compounds Chemical class 0.000 title claims abstract description 16
- 239000003651 drinking water Substances 0.000 title claims abstract description 15
- 235000020188 drinking water Nutrition 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 241000121220 Tricholoma matsutake Species 0.000 claims abstract description 55
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- 239000007788 liquid Substances 0.000 claims description 20
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses compound fullerene healthcare drinking water.The compound fullerene healthcare drinking water is prepared from 5-200 ppm of fullerene, 5-500 ppm of tricholoma matsutake extract and 5-500 ppm of inonotus obliquus extract.The invention further discloses a preparation method of the healthcare drinking water.According to the compound fullerene healthcare drinking water and the preparation method, fullerene is mixed with tricholoma matsutake extract and inonotus obliquus extract to achieve strong oxidation resisting and free radical scavenging, and thus the cancer prevention and anti-cancer effects are achieved; besides, the steps are simple and environmentally friendly; meanwhile, tricholoma matsutake and inonotus obliquus soaked with baijiu can be eaten after being taken out and washed clean, and thus wasting of resources is avoided.
Description
Technical field
The present invention relates to health-care medicament field, particularly to a kind of compound recipe fullerene health-care drinking-water and preparation method thereof.
Background technology
Free radical is the product produced in body oxidation reaction, has strong oxidizing property, can damage tissue and the cell of body, cause cell mutation, and abnormal hypertrophy phenomenon occurs the cell of sudden change, and the cell of hypertrophy is known as cancerous cell.Cancerous cell does not have any function, but can migration everywhere in human body, rob internal nutrient, affect Normocellular growth, and can unrestrictedly replicate growth, transfer to other positions of health, therefore, everyone has very big probability to obtain cancer, and prophylaxis of cancer most efficient method is exactly scavenging free radicals.
Fullerene C20 is a kind of native compound, and each global molecular comprises 60 carbon atoms less than a nanometer.C60 in hydration Fullerene C20 HyFn is a kind of macromolecular structure surrounded by the moisture film of high-sequential.Its natural structure is identical with water-bound under health state.In the composition of human body composition, the content of water about accounts for the 75-80% of body weight.Therefore recover health and should first maintain water to steady statue.
Fullerene is because of containing a large amount of electronics, it is possible to supplements electronics, scavenging free radicals to body cell in time, reaches antioxidative purpose, from preventing cell aberration at all.The biological mechanism of its effect is essentially different with the biological mechanism of many traditional antioxidants.Its non-oxidizability be people be familiar with such as vitamin A, C or E, and hundreds and thousands of times of the antioxidant such as natural carotenoid, flavonoid.Result of study shows for many years, and the compound containing low dose of hydration fullerene has extensive and general biological effect.Its scope is as follows:
1, regulate lipid peroxidation process, and contribute to the normalization of Cell membrane lipids compound, improve its resistance to unfavorable factor；
2, intracellular energy oxidizing process is recovered；
3, the process of active cell differentiation and tissue regeneration；
4, the Antioxidative Defense System of human activin self；
5, there is positive immunomodulating performance and anti-interference immune system；
6, there is lasting antihistamine and antiinflammatory action；
7, there is the performance of antihistamine and blood fat reducing；
8, can effective the liver protecting, heart, neural from radiation；
9, antagonism stomach stain infections, anti-burn and wound healing character have significant curative effect, coordinate gentle antibacterial drug therapy to have better curative effect；
10, there is adaptogen and anti-compression property；
11, age ageing phenomenon (as aging, climacteric, health dehydration etc.) is suppressed
Containing precious active substance matsutakealcohol in Tricholoma matsutake (lto et lmai) Singer, in Tricholoma matsutake (lto et lmai) Singer body containing other any plants a kind of all without special double-strand bioactive substance matsutakealcohol (RNA), it has superpower anti-gene mutation ability and strong antitumaous effect, the automatic toxin secreted by tumor cell of energy, targeting ground is close with tumor cell, combination, by dissolving tumor cell membrane and destroying in double-layer of lipoid entrance cell, close the protein receptor of turning of tumor cell, block the protein synthesis of tumor cell, make tumor cell can not schizogamy so that death；Destroy the DNA gene of tumor cell genetic copying, thus reaching anti-gene mutation, it is suppressed that the purpose of tumor and control tumor recurrence, transfer.
Tricholoma matsutake (lto et lmai) Singer has good anti-tumor activity, and the anti-tumor activity of contained polysaccharide is significantly larger than Ganoderma, occupy the first in 15 kinds of edible fungi with anti-tumor activity.Its sporophore hot water extract (polysaccharide) is to the suppression ratio of white mice sarcoma S-180 up to 91.8%, and the suppression ratio to ehrlich carcinoma is 70%.Additionally there are some researches show, human breast carcinoma (MCF-7) cell line is also had inhibitory action by Tricholoma matsutake (lto et lmai) Singer glycoprotein MTSO, and while effect, it is very low to Normocellular toxicity.Blazei polysaccharide can also induce K562 apoptosis simultaneously, it is suppressed that leukocyte proliferation；Research also shows that liver cancer patient takes Tricholoma matsutake (lto et lmai) Singer after hepatocarcinoma is excised. can significantly improving survival rate, and can make GOT, r-GTP, bilirubin value substantially reduces.
Research shows, the antitumor action of Tricholoma matsutake (lto et lmai) Singer shows as two aspects: be directly kill tumor cell on the one hand.Experiment finds that some albumen contained in Tricholoma matsutake (lto et lmai) Singer can directly kill the cancerous cell of skin carcinoma, uterus carcinoma.Being inducing apoptosis of tumour cell on the other hand, experiment finds that in Tricholoma matsutake (lto et lmai) Singer, some active glucoprotein can pass through the transformation stage suppression HeLa cell proliferation of anticancer S to G2M phase in the cycle, and inducing cell generation tune is died.
Birch is fine and soft among the people as the medicinal fungi treating disease in Russia also referred to as Inonqqus obliquus, belongs to pure Chinese medicine, is the heath-function food of 21 century.Long-term zoopery and clinical experiment show to use Inonqqus obliquus without any side effects, and the drug effect played is divided into following several:
1. treatment diabetes.The cure rate of diabetes is 93% by Komsomlshi drugmaker of Russia Inonqqus obliquus fine powder.
2. antitumaous effect.Kinds of tumor cells (such as mastocarcinoma, lip cancer, gastric cancer, parotid gland cancer, pulmonary carcinoma, skin carcinoma, rectal cancer, Huo Jinsi lymphatic cancer) there is obvious inhibitory action.Prevent cancer cell metastasis, recurrence, strengthen immunocompetence, promote health.And for coordinating the radiotherapy of malignant tumor patient, chemotherapy, strengthen the toleration of patient, alleviate toxic and side effects.
3. prevent and treat acquired immune deficiency syndrome (AIDS).Acquired immune deficiency syndrome (AIDS) is had obvious inhibitory action.
4. defying age.Free radical in purged body, protects cell, extends the division algebraically of passage cell, promotes cell survival, promotes metabolism, thus can slow down aging effectively, long-term taking can life lengthening.
5. effectively suppress infective virus.Can preventing cold.
6. prevent hypertension.It is reported that Inonqqus obliquus is not only a kind of tonic, and be the alleviant of the cleaning agent of blood and pain.
7. improve and Polyglucan cortex.
8. pair hepatitis, gastritis, duodenum stain infections, nephritis have obvious therapeutical effect.And vomiting, diarrhoea, gastrointestinal dysfunction are had therapeutical effect.
Summary of the invention
Goal of the invention: the invention aims to make up the deficiency of existing investigative technique, it is provided that a kind of compound recipe fullerene health-care drinking-water for maintaining healthy.
Technical scheme: a kind of compound recipe fullerene health-care drinking-water, including following component: fullerene 5ppm to 200ppm；Tricholoma matsutake (lto et lmai) Singer extract 5ppm to 500ppm；Phaeoporus obliquus extract 5ppm to 500ppm.
The preparation method that the invention also discloses above-mentioned compound recipe fullerene health-care drinking-water: comprise the following steps:
1) Tricholoma matsutake (lto et lmai) Singer extract is extracted: uniformly punch on Tricholoma matsutake (lto et lmai) Singer or cut into slices by Tricholoma matsutake (lto et lmai) Singer, put in the ethanol that concentration is 52%-70% and soak, 24 to 96 hours, take out Tricholoma matsutake (lto et lmai) Singer, remaining is liquid containing Tricholoma matsutake (lto et lmai) Singer dissolving mixt, liquid heating is purified so that ethanol therein passes through, separated also reclaims, and remaining after purification is water solublity Tricholoma matsutake (lto et lmai) Singer extract；
2) Phaeoporus obliquus extract is extracted: cut into slices by Phaeoporus obliquus, put in 52%-70% ethanol and soak, 30 to 45 days, take out Phaeoporus obliquus sheet, remaining is liquid containing Phaeoporus obliquus dissolving mixt, liquid heating is purified so that ethanol therein is by distilling, it is separated and recovered from, remaining after purification is water solublity Phaeoporus obliquus extract；
3) by step 1) and 2) in obtained Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract add to according to aforementioned proportion with fullerene and pure water be sufficiently mixed and get final product.
Beneficial effect: fullerene is mixed by the present invention with Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract, powerful antioxidation, scavenging free radicals, reach the effect of cancer-resisting, and step is simple and environmentally-friendly；Meanwhile, can also be used to eat after the Tricholoma matsutake (lto et lmai) Singer of soaking in Chinese liquor and Phaeoporus obliquus take out and clean, it is to avoid the wasting of resources.
Detailed description of the invention:
In the present invention, pure water is pure deionized water.
Embodiment 1:
A kind of compound recipe fullerene health-care drinking-water, including following component: fullerene 5ppm；Tricholoma matsutake (lto et lmai) Singer extract 5ppm；Phaeoporus obliquus extract 5ppm, surplus is pure water.
Preparation method is as follows:
1) Tricholoma matsutake (lto et lmai) Singer extract is extracted: by uniformly punching or section on quantitative Tricholoma matsutake (lto et lmai) Singer, put in the ethanol that quantitative concentration is 52%-70% and soak, 24 to 96 hours, take out Tricholoma matsutake (lto et lmai) Singer, remaining is liquid containing Tricholoma matsutake (lto et lmai) Singer dissolving mixt, liquid heating is purified so that ethanol therein passes through, separated also reclaims, and remaining after purification is water solublity Tricholoma matsutake (lto et lmai) Singer extract；
2) Phaeoporus obliquus extract is extracted: cut into slices by Phaeoporus obliquus, put in quantitative 52%-70% ethanol and soak, 30 to 45 days, take out Phaeoporus obliquus sheet, remaining is liquid containing Phaeoporus obliquus dissolving mixt, liquid heating is purified so that ethanol therein is by distilling, it is separated and recovered from, remaining after purification is water solublity Phaeoporus obliquus extract；
3) by step 1) and 2) in obtained Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract add to according to aforementioned proportion with fullerene and pure water be sufficiently mixed and get final product.
Fullerene is mixed by the present invention with Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract, powerful antioxidation, and scavenging free radicals reaches the effect of cancer-resisting, and step is simple and environmentally-friendly；Meanwhile, can also be used to eat after the Tricholoma matsutake (lto et lmai) Singer of soaking in Chinese liquor and Phaeoporus obliquus take out and clean, it is to avoid the wasting of resources.
Embodiment 2:
A kind of compound recipe fullerene health-care drinking-water, including following component: fullerene 200ppm；Tricholoma matsutake (lto et lmai) Singer extract 500ppm；Phaeoporus obliquus extract 500ppm.
Preparation method is as follows:
1) Tricholoma matsutake (lto et lmai) Singer extract is extracted: by uniformly punching or section on Tricholoma matsutake (lto et lmai) Singer, put in the ethanol that quantitative concentration is 52%-70% and soak, 24 to 96 hours, take out Tricholoma matsutake (lto et lmai) Singer, remaining is liquid containing Tricholoma matsutake (lto et lmai) Singer dissolving mixt, liquid heating is purified so that ethanol therein passes through, separated also reclaims, and remaining after purification is water solublity Tricholoma matsutake (lto et lmai) Singer extract；
2) Phaeoporus obliquus extract is extracted: cut into slices by Phaeoporus obliquus, put in quantitative 52%-70% ethanol and soak, 30 to 45 days, take out Phaeoporus obliquus sheet, remaining is liquid containing Phaeoporus obliquus dissolving mixt, liquid heating is purified so that ethanol therein is by distilling, it is separated and recovered from, remaining after purification is water solublity Phaeoporus obliquus extract；
3) by step 1) and 2) in obtained Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract add to according to aforementioned proportion with fullerene and pure water be sufficiently mixed and get final product.
Fullerene is mixed by the present invention with Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract, powerful antioxidation, and scavenging free radicals reaches the effect of cancer-resisting, and step is simple and environmentally-friendly；Meanwhile, can also be used to eat after the Tricholoma matsutake (lto et lmai) Singer of soaking in Chinese liquor and Phaeoporus obliquus take out and clean, it is to avoid the wasting of resources.
Embodiment 3:
A kind of compound recipe fullerene health-care drinking-water, including following component: fullerene 100ppm, extract 100ppm；Phaeoporus obliquus extract 100ppm.
Preparation method is as follows:
1) Tricholoma matsutake (lto et lmai) Singer extract is extracted: by uniformly punching or section on Tricholoma matsutake (lto et lmai) Singer, put in the ethanol that quantitative concentration is 52%-70% and soak, 24 to 96 hours, take out Tricholoma matsutake (lto et lmai) Singer, remaining is liquid containing Tricholoma matsutake (lto et lmai) Singer dissolving mixt, liquid heating is purified so that ethanol therein passes through, separated also reclaims, and remaining after purification is water solublity Tricholoma matsutake (lto et lmai) Singer extract；
2) Phaeoporus obliquus extract is extracted: cut into slices by Phaeoporus obliquus, put in quantitative 52%-70% ethanol and soak, 30 to 45 days, take out Phaeoporus obliquus sheet, remaining is liquid containing Phaeoporus obliquus dissolving mixt, liquid heating is purified so that ethanol therein is by distilling, it is separated and recovered from, remaining after purification is water solublity Phaeoporus obliquus extract；
3) by step 1) and 2) in obtained Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract add to according to aforementioned proportion with fullerene and pure water be sufficiently mixed and get final product.
Fullerene is mixed by the present invention with Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract, powerful antioxidation, and scavenging free radicals reaches the effect of cancer-resisting, and step is simple and environmentally-friendly；Meanwhile, can also be used to eat after the Tricholoma matsutake (lto et lmai) Singer of soaking in Chinese liquor and Phaeoporus obliquus take out and clean, it is to avoid the wasting of resources.
Claims (2)
1. a compound recipe fullerene health-care drinking-water, it is characterised in that: include following component: fullerene 5ppm to 200ppm；Tricholoma matsutake (lto et lmai) Singer extract 5ppm to 500ppm；Phaeoporus obliquus extract 5ppm to 500ppm.
2. the preparation method of compound recipe fullerene health-care drinking-water as claimed in claim 1, it is characterised in that: comprise the following steps:
1) Tricholoma matsutake (lto et lmai) Singer extract is extracted: uniformly punch on Tricholoma matsutake (lto et lmai) Singer or cut into slices by Tricholoma matsutake (lto et lmai) Singer, put in the ethanol that concentration is 52%-70% and soak, 24 to 96 hours, take out Tricholoma matsutake (lto et lmai) Singer, remaining is liquid containing Tricholoma matsutake (lto et lmai) Singer dissolving mixt, liquid heating is purified so that ethanol therein, by separated reclaiming, remaining after purification is water solublity Tricholoma matsutake (lto et lmai) Singer extract；
2) Phaeoporus obliquus extract is extracted: cut into slices by Phaeoporus obliquus, put in quantitative 52%-70% ethanol and soak, 30 to 45 days, take out Phaeoporus obliquus sheet, remaining is liquid containing Phaeoporus obliquus dissolving mixt, liquid heating is purified so that ethanol therein is by distilling, it is separated and recovered from, remaining after purification is water solublity Phaeoporus obliquus extract；
3) by step 1) and 2) in obtained Tricholoma matsutake (lto et lmai) Singer extract, Phaeoporus obliquus extract add to according to aforementioned proportion with fullerene and pure water be sufficiently mixed and get final product.
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| CN201610229251.6A CN105796608A (en) | 2016-04-13 | 2016-04-13 | Compound fullerene healthcare drinking water and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753511A (en) * | 2016-08-15 | 2018-03-06 | 中国科学院化学研究所 | The medicine of purposes and protection spleen of the fullerene in medicine is prepared |
| CN107753512A (en) * | 2016-08-15 | 2018-03-06 | 中国科学院化学研究所 | The medicine of purposes and protection kidney of the fullerene in medicine is prepared |
| CN107753513A (en) * | 2016-08-15 | 2018-03-06 | 北京福纳康生物技术有限公司 | Purposes and liver-protective medicine of the fullerene in medicine is prepared |
| WO2023113708A1 (en) * | 2021-12-15 | 2023-06-22 | Ckr Bi̇li̇şi̇m Gida Organi̇zasyon Hi̇zmetleri̇ Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Mineral water and water and concentrate enriched with c60 and aronia or elderberry |
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| CN1327433A (en) * | 1999-10-22 | 2001-12-19 | 法伊鲁特股份有限公司 | Method and apparatus for producing fullerene water |
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| CN1327433A (en) * | 1999-10-22 | 2001-12-19 | 法伊鲁特股份有限公司 | Method and apparatus for producing fullerene water |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107753511A (en) * | 2016-08-15 | 2018-03-06 | 中国科学院化学研究所 | The medicine of purposes and protection spleen of the fullerene in medicine is prepared |
| CN107753512A (en) * | 2016-08-15 | 2018-03-06 | 中国科学院化学研究所 | The medicine of purposes and protection kidney of the fullerene in medicine is prepared |
| CN107753513A (en) * | 2016-08-15 | 2018-03-06 | 北京福纳康生物技术有限公司 | Purposes and liver-protective medicine of the fullerene in medicine is prepared |
| WO2023113708A1 (en) * | 2021-12-15 | 2023-06-22 | Ckr Bi̇li̇şi̇m Gida Organi̇zasyon Hi̇zmetleri̇ Sanayi̇ Ve Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Mineral water and water and concentrate enriched with c60 and aronia or elderberry |
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