CN105796109A - Mouse coldness and heat approach behavior tester - Google Patents
Mouse coldness and heat approach behavior tester Download PDFInfo
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- CN105796109A CN105796109A CN201610130791.9A CN201610130791A CN105796109A CN 105796109 A CN105796109 A CN 105796109A CN 201610130791 A CN201610130791 A CN 201610130791A CN 105796109 A CN105796109 A CN 105796109A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
- A61B5/1105—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs of laboratory animals, e.g. activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
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Abstract
The invention discloses a mouse coldness and heat approach behavior tester which comprises a heat box, a room temperature box and a coldness box. The heat box and the coldness box are arranged on the two sides of the room temperature box respectively. Partition plates are arranged inside the heat box, the room temperature box and the coldness box. The three boxes are partitioned into partitions through the partition plates, wherein the numbers of the partitions of the three boxes are equal. Small doors are arranged between the partitions at the same positions inside different boxes. A photoelectric switch is arranged on the top of each small door. A heating device is arranged on the side wall of each partition inside the heat box. A refrigeration device is arranged on the side wall of each partition inside the coldness box. A control panel is installed on the side wall of the coldness box. The tester is internally divided into a plurality of partitions, multiple sets of tests can be performed at the same time, the test result occasionality is eliminated, and the test credibility is enhanced.
Description
Technical field
The present invention relates to a kind of mice cold and heat approach behavior analyzer.
Background technology
At present, index many employings anus gentleness toe temperature of reflection mice cold and heat attribute, evaluate the cold and heat body constitution of mice with the height of anus gentleness toe temperature or medicine acts on the cold and heat effect that mice embodies, but these indexs are by the interference of extraneous anthropic factor, can not well reflect the cold and heat approach behavior of mice.The instrument and equipment of specific determination mice cold and heat approach behavior is there is presently no through retrieval.
The patent No.: CN101301223A discloses a kind of rat cold and heat approach behavior analyzer, this instrument can pass through to observe the cold and heat of the general behavior performance measurement mice of mice to be tended to, it is mainly used in cold and heat body constitution and the impact on rat cold and heat approach behavior of the Chinese medicine cold and heat property of medicine of research rat, and then the change of the cold and heat feature acting on rat cold, hot, warm, cool of four gas theoretical drug of Study of Traditional Chinese Medicine, can better and objectively embody traditional Chinese medical science differentiating cold syndrome and heat syndrome characteristic.According to theory of Chinese medical science, cold body constitution person is addicted to hotter environment, and febricity body constitution person is then addicted to relatively cold environment.The body constitution of experimental animal also has partially thermophilic or inclined to cold tendency；On the other hand during morbid state, can there is the change of cold and heat attribute in body, make patient to partial heat or partially cold environment move and keep here.Disclosed rat cold and heat approach behavior analyzer is exactly a kind of three simultaneous mensuration environment of different temperatures of artificial manufacture, with observe different rats under normal circumstances, morbid state time and treatment after preference to cold and heat environment, it is intended to record rat by objective index and produces thermophilic or residence time in this context during addicted to cold environment, and then infer the body constitution situation of rat, ill time cold and heat partially addicted to, and also the rat that medication is later can be carried out the evaluation of curative effect.
But, a rat once can only be carried out cold and heat by disclosed rat cold and heat approach behavior analyzer to tend to measure, and test efficiency is low, and single group test simultaneously increases the occasionality of test, makes result of the test not accurate enough.
Summary of the invention
In order to solve the problems referred to above, the present invention proposes a kind of mice cold and heat approach behavior analyzer, this instrument possesses following characteristics: be (1) divided into several intervals inside analyzer, many mices can be tested simultaneously, eliminate the occasionality of result of the test, (2) increase the credibility of test, improve test efficiency.(3) behavior whole process shooting mice cold and heat tended to is followed the tracks of, and records the indexs such as its cold and heat trend and cold and heat case holdup time in real time, objectively, and retains coherent video data.(4) possess light prompt function, the living environment of inconspicuous change mice.(5) access computer system, use computer software that index of correlation carries out objective analysis and data statistics.(6) fan can promote that air flows, it is ensured that the temperature inside the box is balanced.
To achieve these goals, the present invention adopts the following technical scheme that
A kind of mice cold and heat approach behavior analyzer, including hot tank, room temperature case and cold case, described hot tank and cold case are separately positioned on the both sides of room temperature case, described hot tank, it is designed with dividing plate in room temperature case and cold case, three above-mentioned casees are respectively classified into several equal numbers of intervals by described dividing plate, it is provided with wicket between the interval of the same position in different casees, the top of each wicket is designed with photoswitch, each spaced-apart sidewalls in described hot tank is designed with heater, each spaced-apart sidewalls in described cold case is designed with refrigerating plant, the sidewall of described cold case is provided with control panel.Several intervals will be divided into inside analyzer, it is possible to carry out organizing test more simultaneously, eliminate the occasionality of result of the test, increase the credibility of test.
The top, each interval of described room temperature case is provided with illuminator.Illuminator is set and analyzer inside can be carried out the simulation of day and night, improve the versatility of analyzer.
Described illuminator is cold light source.Adopt cold light source, make light-source temperature in lighting process to raise, it is to avoid the temperature that light source produces affects the temperature in room temperature case.
The top, each interval of described room temperature case is additionally provided with photographic head.Situation in respective interval is monitored by photographic head in each interval respectively, processes emergency situations in time, makes test have more specific aim.
The facade that each interval of described hot tank and cold case is relative with room temperature case is designed with fan.Fan can make the air in interval flow, it is possible to quickly makes whole interval reach constant temperature, it is ensured that the accuracy of test effect.
Described heater is general heater strip.Use commercially available general heating silk, greatly reduce the production cost of equipment, facilitate the maintenance in later stage simultaneously.
Described refrigerating plant is general refrigerating plant.Use commercially available general refrigerating plant, greatly reduce the production cost of equipment, facilitate the maintenance in later stage simultaneously.
The top of described hot tank, room temperature case and cold case is designed with the top cover of activity.Top cover is arranged to activity, it is possible to open the situation in treatment box easily, facilitate picking and placeing of trier simultaneously.
Six faces of described hot tank, room temperature case and cold case are opaque black.Three casees are set to opaque black, it is to avoid extraneous light source enters in case, affects result of the test.
Described control panel can be connected with computer, carries out data sharing and computer controls.Analyzer is connected with computer by control panel, it is achieved data sharing and monitor in real time, by using computer that analyzer is controlled, it is achieved the complete monitoring of dynamic test process, improves the credibility of test.
The invention have the benefit that
(1) present invention arranges multiple interval, it is possible to many group mices is tested simultaneously, improves the accuracy of test；
(2) present invention can be connected with computer, it is achieved that real time data acquisition is also shared；
(3) present invention is provided with illuminator and photographic head in room temperature case, it is possible to simulation daytime and night two kinds of trystates, the mice in room temperature case can be monitored simultaneously.
Accompanying drawing explanation
Fig. 1 is the overall structure schematic diagram of the present invention；
Wherein, 1, hot tank, 2, dividing plate, 3, illuminator, 4, photographic head, 5, room temperature case, 6, cold case, 7, control panel, 8, fan, 9, refrigerating plant, 10, wicket, 11, photoswitch, 12, heater.
Detailed description of the invention:
Below in conjunction with accompanying drawing, the invention will be further described with embodiment.
As shown in Figure 1, a kind of mice cold and heat approach behavior analyzer, including hot tank 1, room temperature case 5 and cold case 6, hot tank 1 and cold case 6 are separately positioned on the both sides of room temperature case 5, hot tank 1, it is designed with dividing plate 2 in room temperature case 5 and cold case 6, three above-mentioned casees are respectively classified into several equal numbers of intervals by dividing plate 2, interval number is one or more, it is provided with wicket 10 between the interval of the same position in different casees, the top of each wicket 10 is designed with photoswitch 11, whether photoswitch 11 can sense mice by wicket 10, each spaced-apart sidewalls in hot tank 1 is designed with heater 12, heater 12 is general heater strip, use commercially available general heating silk, greatly reduce the production cost of equipment, facilitate the maintenance in later stage simultaneously.The top, each interval of room temperature case 5 is provided with illuminator 3, arranges illuminator 3 and analyzer inside can carry out the simulation of day and night, improve the versatility of analyzer.Illuminator 3 is cold light source, adopts cold light source, makes light-source temperature in lighting process to raise, it is to avoid the temperature that light source produces affects the temperature in room temperature case.The top, each interval of room temperature case 5 is additionally provided with photographic head 4, and the situation in respective interval is monitored by photographic head 4 in each interval respectively, processes emergency situations in time, makes test have more specific aim.Being designed with refrigerating plant in each spaced-apart sidewalls in cold case 6, refrigerating plant is general refrigerating plant 9.Use commercially available general refrigerating plant 9, greatly reduce the production cost of equipment, facilitate the maintenance in later stage simultaneously.The sidewall of cold case 6 is provided with control panel 7.Control panel 7 can be connected with computer, carries out data sharing and computer controls.Analyzer is connected with computer by control panel 7, it is achieved data sharing and monitor in real time, by using computer that analyzer is controlled, it is achieved the complete monitoring of dynamic test process, improves the credibility of test.Being designed with fan 8 on the facade that each interval of hot tank 1 and cold case 6 is relative with room temperature case 5, fan 8 can make the air in interval flow, it is possible to quickly makes whole interval reach constant temperature, it is ensured that the accuracy of test effect.The top of hot tank 1, room temperature case and cold case 6 is designed with the top cover of activity.Top cover is arranged to activity, it is possible to open the situation in treatment box easily, facilitate picking and placeing of trier simultaneously.Six faces of hot tank 1, room temperature case 5 and cold case 6 are opaque black, and three casees are set to opaque black, it is to avoid extraneous light source enters in case, affects result of the test.Several intervals will be divided into inside analyzer, it is possible to carry out organizing test more simultaneously, eliminate the occasionality of result of the test, increase the credibility of test.
In the present embodiment, the inside dimension of hot tank 1, room temperature case 5 and cold case 6 is long 30cm, wide 30cm, high 30cm, employing square is arranged, interval in each case arranges three simultaneously, namely the inner space of hot tank 1, room temperature case 5 and cold case 6 is all divided into three little spaces, and such mice passage is 3, each channel width 10cm, the wherein wicket size between each case, namely the height of the door that mice enters hot tank 1 and cold case 6 at room temperature case 5 is arranged to 4cm, and width is arranged to 5cm.
During use, first mice cold and heat approach behavior analyzer is placed in the test chamber of constant temperature, the test chamber temperature of standard is 22 DEG C～24 DEG C, set room temperature as 23 DEG C now, the top cover of room temperature case 5 is opened, keep consistent with room temperature, the heater 12 of hot tank 1 and the refrigerating plant of cold case 6 is opened respectively by control panel 7, the temperature making hot tank 1 is 25 DEG C, the temperature of cold case 6 is 21 DEG C, and respectively the temperature in hot tank 1 and cold case 6 is detected by temperature sensor, make variations in temperature keep within the limits prescribed.When the temperature in two casees reaches after stably.The mice taking many tests is put in each interval of room temperature case 5 respectively, top cover.Now the temperature in room temperature case 5 remains 23 DEG C.Mice cold and heat approach behavior analyzer is connected by control panel 7 and computer, control panel 7 is opened the switch of the photoswitch 11 of hot tank 1 and cold case 6, now namely photoswitch 11 can experience whether mice enters hot tank 1 or cold case 6, and is shown by computer.Owing to being provided with wicket 10 between room temperature case 5 and hot tank 1 and cold case 6, steam or cold air can be had from wicket 10 to shed, mice can experience different temperature air-flows, even if in dark environment, it is entered in a certain case by duck eye also with to the impression of temperature.Such as mice enters hot tank 1, then the photoswitch 11 in this case starts, and instruction time hour totalizer is started working, to record mice residence time in hot tank 1, after mice leaves hot tank 1, photoswitch 11 is experienced mice and is left away, then instruction time hour totalizer stops the record time.After the cold case 6 of mice entrance, the work of analyzer is as the same.Test mice is after being placed into analyzer in a word, its thermophilic or addicted to cold tendency body constitution urges it in hot tank 1 or cold case 6, then to record mice residence time in which case long for the time cumulation timer of analyzer, then show that this mice has the tendency addicted to this case temperature.If mice is not recorded in hot tank 1 or the record of cold case 6 time of staying, then illustrating that mice is in room temperature case, further relating to this mice does not have thermophilic or addicted to cold tendency, belongs to normal body constitution.Test data are by sharing with computer, it is possible to storage is on computers.
The specific embodiment of the present invention is described in conjunction with accompanying drawing although above-mentioned; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme, those skilled in the art need not pay various amendments or deformation that creative work can make still within protection scope of the present invention.
Claims (10)
1. a mice cold and heat approach behavior analyzer, it is characterized in that: include hot tank, room temperature case and cold case, described hot tank and cold case are separately positioned on the both sides of room temperature case, described hot tank, it is designed with dividing plate in room temperature case and cold case, three above-mentioned casees are respectively classified into several equal numbers of intervals by described dividing plate, it is provided with wicket between the interval of the same position in different casees, the top of each wicket is designed with photoswitch, each spaced-apart sidewalls in described hot tank is designed with heater, each spaced-apart sidewalls in described cold case is designed with refrigerating plant, the sidewall of described cold case is provided with control panel.
2. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: the top, each interval of described room temperature case is provided with illuminator.
3. a kind of mice cold and heat approach behavior analyzer as claimed in claim 2, is characterized in that: described illuminator is cold light source.
4. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: the top, each interval of described room temperature case is additionally provided with photographic head.
5. mice cold and heat approach behavior analyzer as claimed in claim 1 a kind of, is characterized in that: be designed with fan on the facade that each interval of described hot tank and cold case is relative with room temperature case.
6. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: described heater is general heater strip.
7. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: described refrigerating plant is general refrigerating plant.
8. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: the top of described hot tank, room temperature case and cold case is designed with the top cover of activity.
9. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: six faces of described hot tank, room temperature case and cold case are opaque black.
10. a kind of mice cold and heat approach behavior analyzer as claimed in claim 1, is characterized in that: described control panel can be connected with computer, carries out data sharing and computer controls.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610130791.9A CN105796109A (en) | 2016-03-08 | 2016-03-08 | Mouse coldness and heat approach behavior tester |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610130791.9A CN105796109A (en) | 2016-03-08 | 2016-03-08 | Mouse coldness and heat approach behavior tester |
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| CN105796109A true CN105796109A (en) | 2016-07-27 |
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| CN201610130791.9A Pending CN105796109A (en) | 2016-03-08 | 2016-03-08 | Mouse coldness and heat approach behavior tester |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301223A (en) * | 2008-06-24 | 2008-11-12 | 山东中医药大学 | Rat chills and fever approach behavior determinator |
| CN102389291A (en) * | 2011-06-09 | 2012-03-28 | 广西中医学院 | Experimental animal sign information collection and analysis system and collection and analysis method |
| CN103621444A (en) * | 2013-12-03 | 2014-03-12 | 山东中医药大学 | Zebra fish temperature-sensitive behavior track monitor and detection method for effects of cold-heat drug natures of trace ingredients of traditional Chinese medicines |
-
2016
- 2016-03-08 CN CN201610130791.9A patent/CN105796109A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101301223A (en) * | 2008-06-24 | 2008-11-12 | 山东中医药大学 | Rat chills and fever approach behavior determinator |
| CN102389291A (en) * | 2011-06-09 | 2012-03-28 | 广西中医学院 | Experimental animal sign information collection and analysis system and collection and analysis method |
| CN103621444A (en) * | 2013-12-03 | 2014-03-12 | 山东中医药大学 | Zebra fish temperature-sensitive behavior track monitor and detection method for effects of cold-heat drug natures of trace ingredients of traditional Chinese medicines |
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Application publication date: 20160727 |
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