CN105771316B8 - Automatic control system and method for panax notoginseng saponins column chromatography process - Google Patents

Automatic control system and method for panax notoginseng saponins column chromatography process Download PDF

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Publication number
CN105771316B8
CN105771316B8 CN201610284671.4A CN201610284671A CN105771316B8 CN 105771316 B8 CN105771316 B8 CN 105771316B8 CN 201610284671 A CN201610284671 A CN 201610284671A CN 105771316 B8 CN105771316 B8 CN 105771316B8
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CN
China
Prior art keywords
panax notoginseng
automatic control
column chromatography
control system
notoginseng saponins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610284671.4A
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Chinese (zh)
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CN105771316A (en
CN105771316B (en
Inventor
方同华
程翼宇
瞿海斌
许照芹
席桂才
张永年
王春生
孙海峰
孙淑娜
季庆亮
徐秀杰
周广红
贾文娟
王维龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heilongjiang, Chen-pao Island, Limited by Share Ltd
Original Assignee
HEILONGJIANG ZBD PHARMACEUTICAL CO Ltd
Harbin Zhenbao Pharmaceutical Co ltd
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Application filed by HEILONGJIANG ZBD PHARMACEUTICAL CO Ltd, Harbin Zhenbao Pharmaceutical Co ltd filed Critical HEILONGJIANG ZBD PHARMACEUTICAL CO Ltd
Priority to CN201610284671.4A priority Critical patent/CN105771316B8/en
Publication of CN105771316A publication Critical patent/CN105771316A/en
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Publication of CN105771316B publication Critical patent/CN105771316B/en
Publication of CN105771316B8 publication Critical patent/CN105771316B8/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/163—Pressure or speed conditioning
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00—Programme-control systems
    • G05B19/02—Programme-control systems electric
    • G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers

Abstract

The invention relates to an automatic control system and method for a panax notoginseng saponins column chromatography process, wherein the automatic control system comprises a control computer, a pump connected with the control computer, a chromatographic column connected with the pump, and a detector connected with the chromatographic column and the control computer. The method can realize automatic control, quantitative elution and fine control of the panax notoginseng saponins column chromatography elution process, improve the batch-to-batch consistency of the panax notoginseng saponins intermediate, and is beneficial to energy conservation and consumption reduction in the elution process and economic benefit improvement.
CN201610284671.4A 2016-05-03 2016-05-03 Automatic control system and method for panax notoginseng saponins column chromatography process Active CN105771316B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610284671.4A CN105771316B8 (en) 2016-05-03 2016-05-03 Automatic control system and method for panax notoginseng saponins column chromatography process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610284671.4A CN105771316B8 (en) 2016-05-03 2016-05-03 Automatic control system and method for panax notoginseng saponins column chromatography process

Publications (3)

Publication Number Publication Date
CN105771316A CN105771316A (en) 2016-07-20
CN105771316B CN105771316B (en) 2017-12-22
CN105771316B8 true CN105771316B8 (en) 2020-08-04

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110348090B (en) * 2019-06-28 2021-05-04 浙江大学 Method for realizing multi-column continuous flow chromatography design and analysis based on artificial neural network

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359320A2 (en) * 1988-09-14 1990-03-21 Philips Electronics Uk Limited Chromatography apparatus
US20070108126A1 (en) * 2005-11-17 2007-05-17 Lee Dian Y Dynamic Flow Liquid Chromatography
CN103969375A (en) * 2013-01-29 2014-08-06 深圳普门科技有限公司 An elution method for liquid chromatography and inspection equipment thereof
CN204767602U (en) * 2015-07-17 2015-11-18 吉首大学 Chromatography column piece -rate system
CN205730460U (en) * 2016-05-03 2016-11-30 哈尔滨珍宝制药有限公司 Radix Notoginseng total arasaponins column chromatography procedure automatic control system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359320A2 (en) * 1988-09-14 1990-03-21 Philips Electronics Uk Limited Chromatography apparatus
US20070108126A1 (en) * 2005-11-17 2007-05-17 Lee Dian Y Dynamic Flow Liquid Chromatography
CN103969375A (en) * 2013-01-29 2014-08-06 深圳普门科技有限公司 An elution method for liquid chromatography and inspection equipment thereof
CN204767602U (en) * 2015-07-17 2015-11-18 吉首大学 Chromatography column piece -rate system
CN205730460U (en) * 2016-05-03 2016-11-30 哈尔滨珍宝制药有限公司 Radix Notoginseng total arasaponins column chromatography procedure automatic control system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
基于近红外光谱的中药过程分析方法研究;杨南林;《中国博士学位论文全文数据库（电子期刊）工程科技I辑》;20040315(第1期);75-76,118-119 *

Also Published As

Publication number Publication date
CN105771316A (en) 2016-07-20
CN105771316B (en) 2017-12-22

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20170628

Address after: 150060 Heilongjiang province Harbin Development Zone Road haping road centralized District No. 8 Yantai

Applicant after: Haerbin Zhenbao Pharmaceutical Co., Ltd.

Applicant after: Heilongjiang, Chen-pao Island, Limited by Share Ltd

Address before: 150060 Heilongjiang city of Harbin province Harbin Development Zone Road haping road centralized District No. 8 Yantai

Applicant before: Haerbin Zhenbao Pharmaceutical Co., Ltd.

GR01 Patent grant
GR01 Patent grant
CI03 Correction of invention patent
CI03 Correction of invention patent

Correction item: Applicant|Address|Applicant

Correct: Haerbin Zhenbao Pharmaceutical Co., Ltd.|150060 Heilongjiang province Harbin Development Zone Road haping road centralized District No. 8 Yantai|Heilongjiang ZBD Pharmaceutical Co., Ltd.

False: Haerbin Zhenbao Pharmaceutical Co., Ltd.|150060 Heilongjiang province Harbin Development Zone Road haping road centralized District No. 8 Yantai|Heilongjiang, Chen-pao Island, Limited by Share Ltd

Number: 29-01

Volume: 33

CI03 Correction of invention patent
CI03 Correction of invention patent

Correction item: Patentee|Address|Patentee

Correct: Harbin Zhenbao Pharmaceutical Co., Ltd|150060 No. 8, Yantai 1st Road, Harbin Development Zone, Heilongjiang Province|Heilongjiang Zhenbaodao Pharmaceutical Co., Ltd

False: Harbin Zhenbao Pharmaceutical Co., Ltd|150060 No. 8, Yantai 1st Road, Harbin Development Zone, Heilongjiang Province|Heilongjiang Zhenbaodao Co., Ltd

Number: 51-02

Volume: 33

Correction item: Patentee|Address|Patentee

Correct: Harbin Zhenbao Pharmaceutical Co., Ltd|150060 No. 8, Yantai 1st Road, Harbin Development Zone, Heilongjiang Province|Heilongjiang Zhenbaodao Pharmaceutical Co., Ltd

False: Harbin Zhenbao Pharmaceutical Co., Ltd|150060 No.8, Yantai 1st Road, Harbin Development Zone, Heilongjiang Province|Heilongjiang Zhenbaodao Co., Ltd

Number: 51-02

Page: The title page

Volume: 33