CN105769586A - Carrying mesoporous binder for dentistry - Google Patents
Carrying mesoporous binder for dentistry Download PDFInfo
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- CN105769586A CN105769586A CN201410799213.5A CN201410799213A CN105769586A CN 105769586 A CN105769586 A CN 105769586A CN 201410799213 A CN201410799213 A CN 201410799213A CN 105769586 A CN105769586 A CN 105769586A
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- mesoporous
- binding agent
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- gear division
- loading according
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Abstract
The invention provides a carrying mesoporous binder for dentistry. The carrying mesoporous binder is mainly prepared from, by mass, 30-40 parts of calcium oxide, 5-10 parts of sulfur oxide, 45-55 parts of phenolic resin ingredients, 35-45 parts of esters solvent, 0.5-1 part of zwitter-ion surfactant, 8-12 parts of monopotassium phosphate, 0.15-0.25 part of polyurethane adhesive accelerant, 2-11 parts of mesoporous material and 60-70 parts of structured packing. The carrying mesoporous binder overcomes the defect of an existing binder and has the effect of carrying drugs and preparations, the drugs are released to speed up wound healing, and the added preparations can strengthen and whiten the teeth, the binding force is high, the inflammation diminishing effect is good, and no toxic or side effect exists.
Description
Technical field
The invention relates to gear division binding agent field, especially the mesoporous gear division binding agent of loading.
Background technology
Mesoporous material has a lot of unique performance, can be applicable to many fields such as catalysis, absorption, separation, sensing, electrode and drug release.It is because having very big specific surface area and pore volume, it is possible to fix the bio-pharmaceuticals such as embedding albumen in the duct of material, by modified with functional group controlled release drug, improving the persistency of drug effect.Therefore, add mesoporous material in a binder and can increase the function of binding agent.If being loaded into hemostasis, antiinflammatory, the medicine such as antibacterial in mesoporous material duct, then will the treatment function of lifting binding agent.The present invention, using mesoporous material as inorganic filler, prepares the dental cement that adhesion strength is high.
The adhesive strength of the binding agent being widely used at present is not high, and function is also more single.The research and development of so this loading mesoporous gear division binding agent are just necessary, and it can not only play good bond effect, and can also accelerate wound healing, reduce the misery of patient.
Summary of the invention
The problem that the invention to solve is to allow common bond have loading function.
For solving above-mentioned technical problem, the invention the technical scheme is that mesoporous its key component of gear division binding agent of loading and mass fraction thereof are:
Preferably, phenolic resin composition is 49-53%；
Preferably, lipid solvent is at least one in acrylate, isopropyl acetate, propyl acetate and binary alcohol esters.
Preferably, anion surfactant in zwitterionic surfactant: cationic surfactant=2-3:1-2, anion surfactant is amino acid pattern, and cationic surfactant is at least one in carboxylic acid group's glycine betaine, sulfobetaines, phosphate ester glycine betaine and imidazoline type.
Preferably, potassium dihydrogen phosphate PH is between 4.45-4.69.
Preferably, adhesive for polyurethane is triethylene diamine, dibutyl tin laurate with accelerator, stannous octoate and at least one in praseodynium aluminum.
Preferably, mesoporous material is silicon-based mesoporous material.
The invention has the advantage that and has the benefit effect that the compatibility strengthening mesoporous material with binding agent, forms organic-inorganic hybrid material, thus improving the intensity of binding agent.Mesoporous material makes binding agent be conducive to the combination with medicine, thus the advantage playing the medicines such as bag load and controlled release antibiotic agent, anti-inflammatory drug, haemostatic medicament.Make binding agent can not only play cementation, and there is the effect of certain treatment and host defense against bacterial infection.
Detailed description of the invention
Embodiment 1:
The preparation method of mesoporous material: dissolve the phenolic resin of 50 parts in 1000mL water, after stirring 20 minutes, adds 8mmolKOH.Isopropyl acetate is dropwise dripped after being stirred vigorously.Mixture is slowly stirred 12 hours at 27 DEG C, the product obtained at room temperature ageing 10 hours, uses second distillation water washing afterwards.Dry 12 hours under 80 DEG C of vacuum environments, finally calcine 6 hours in 550 DEG C of dry air atmosphere.Add the calcium oxide of 30 parts and the sulfur oxide of 5 parts afterwards in the solution, add the zwitterionic surfactant of 0.5 part, reflux 24 hours at 60 DEG C.Product deionized water, methanol gradually wash twice respectively, at room temperature naturally dry, and obtain required mesoporous material.
The preparation method of loading mesoporous material: be dissolved in the structured packing of 60 parts by the potassium dihydrogen phosphates of 8 parts, is subsequently adding the mesoporous material of 15 parts prepared, and subsequently by product filtration washing 3 times in deionized water, obtains loading mesoporous material after dry 24h.
The preparation method of binding agent: add the triethylene diamine of 0.15 part in 2 parts of mesoporous materials, be stirred for the 55min solution becoming homogeneous, then solution is cooled down.Add the loading mesoporous material of 1 part, stir 8 hours so that it is mix homogeneously.Noting lucifuge in whipping process, then obtain binding agent, namely binding agent solidifies after 5 seconds under light-solidified lamp irradiates.
Embodiment 2:
The preparation method of mesoporous material: dissolve the phenolic resin of 52 parts in 1000mL water, after stirring 30 minutes, adds 12mmolKOH.Propyl acetate is dropwise dripped after being stirred vigorously.Mixture is slowly stirred 15 hours at 30 DEG C, the product obtained at room temperature ageing 12 hours, uses second distillation water washing afterwards.Dry 15 hours under 100 DEG C of vacuum environments, finally calcine 8 hours in 700 DEG C of dry air atmosphere.Add the calcium oxide of 40 parts and the sulfur oxide of 10 parts afterwards in the solution, add the zwitterionic surfactant of 0.7 part, reflux 18 hours at 80 DEG C.Product deionized water, methanol gradually wash twice respectively, at room temperature naturally dry, and obtain required mesoporous material.
The preparation method of loading mesoporous material: be dissolved in the structured packing of 70 parts by the potassium dihydrogen phosphates of 10 parts, is subsequently adding the mesoporous material of 20 parts prepared, and subsequently by product filtration washing 2 times in deionized water, obtains loading mesoporous material after dry 25h.
The preparation method of binding agent: add the dibutyl tin laurate of 0.17 part in 2 parts of mesoporous materials, be stirred for the 60min solution becoming homogeneous, then solution is cooled down.Add the loading mesoporous material of 3 parts, stir 10 hours so that it is mix homogeneously.Noting lucifuge in whipping process, then obtain binding agent, namely binding agent solidifies after 5 seconds under light-solidified lamp irradiates.
Embodiment 3:
The preparation method of mesoporous material: dissolve the phenolic resin of 55 parts in 1000mL water, after stirring 40 minutes, adds 15mmolKOH.Binary alcohol esters is dropwise dripped after being stirred vigorously.Mixture is slowly stirred 20 hours at 50 DEG C, the product obtained at room temperature ageing 15 hours, uses second distillation water washing afterwards.Dry 20 hours under 150 DEG C of vacuum environments, finally calcine 10 hours in 1000 DEG C of dry air atmosphere.Add the calcium oxide of 50 parts and the sulfur oxide of 9 parts afterwards in the solution, add the zwitterionic surfactant of 0.9 part, reflux 20 hours at 100 DEG C.Product deionized water, methanol gradually wash twice respectively, at room temperature naturally dry, and obtain required mesoporous material.
The preparation method of loading mesoporous material: be dissolved in the structured packing of 70 parts by the potassium dihydrogen phosphates of 12 parts, is subsequently adding the mesoporous material of 25 parts prepared, and subsequently by product filtration washing 4 times in deionized water, obtains loading mesoporous material after dry 27h.
The preparation method of binding agent: add the praseodynium aluminum of 0.18 part in 2 parts of mesoporous materials, be stirred for the 80min solution becoming homogeneous, then solution is cooled down.Add the loading mesoporous material of 6 parts, stir 14 hours so that it is mix homogeneously.Noting lucifuge in whipping process, then obtain binding agent, namely binding agent solidifies after 5 seconds under light-solidified lamp irradiates.
Above the embodiment of the invention is described in detail, but described content has been only the preferred embodiment of the invention, it is impossible to be considered the practical range for limiting the present invention.All equalizations made according to the invention scope change and improvement etc., all should still belong within this patent covering scope.
Claims (7)
1. the mesoporous gear division binding agent of loading, it is characterised in that its key component and mass fraction thereof be:
。
2. the mesoporous gear division binding agent of loading according to claim 1, it is characterised in that: described phenolic resin composition is 49-53%.
3. the mesoporous gear division binding agent of loading according to claim 1, it is characterised in that: described lipid solvent is at least one in acrylate, isopropyl acetate, propyl acetate and binary alcohol esters.
4. the mesoporous gear division binding agent of loading according to claim 1, it is characterized in that: anion surfactant in described zwitterionic surfactant: cationic surfactant=2-3:1-2, anion surfactant is amino acid pattern, and cationic surfactant is at least one in carboxylic acid group's glycine betaine, sulfobetaines, phosphate ester glycine betaine and imidazoline type.
5. the mesoporous gear division binding agent of loading according to claim 1, it is characterised in that: described potassium dihydrogen phosphate PH is between 4.45-4.69.
6. the mesoporous gear division binding agent of loading according to claim 1, it is characterised in that: described adhesive for polyurethane is triethylene diamine, dibutyl tin laurate with accelerator, stannous octoate and at least one in praseodynium aluminum.
7. the mesoporous gear division binding agent of loading according to claim 1, it is characterised in that: described mesoporous material is silicon-based mesoporous material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410799213.5A CN105769586A (en) | 2014-12-19 | 2014-12-19 | Carrying mesoporous binder for dentistry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410799213.5A CN105769586A (en) | 2014-12-19 | 2014-12-19 | Carrying mesoporous binder for dentistry |
Publications (1)
| Publication Number | Publication Date |
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| CN105769586A true CN105769586A (en) | 2016-07-20 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410799213.5A Pending CN105769586A (en) | 2014-12-19 | 2014-12-19 | Carrying mesoporous binder for dentistry |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272263A (en) * | 2013-05-22 | 2013-09-04 | 无锡市华明化工有限公司 | Medical adhesive |
| CN103610598A (en) * | 2013-11-28 | 2014-03-05 | 江苏科技大学 | Bionic dental adhesive composition and preparation method thereof |
| CN103655207A (en) * | 2013-12-04 | 2014-03-26 | 上海纳米技术及应用国家工程研究中心有限公司 | Drug-loaded mesoporous-silica-reinforced dental binder and preparation method thereof |
-
2014
- 2014-12-19 CN CN201410799213.5A patent/CN105769586A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103272263A (en) * | 2013-05-22 | 2013-09-04 | 无锡市华明化工有限公司 | Medical adhesive |
| CN103610598A (en) * | 2013-11-28 | 2014-03-05 | 江苏科技大学 | Bionic dental adhesive composition and preparation method thereof |
| CN103655207A (en) * | 2013-12-04 | 2014-03-26 | 上海纳米技术及应用国家工程研究中心有限公司 | Drug-loaded mesoporous-silica-reinforced dental binder and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 《化工百科全书》编辑委员会: "《化工百科全书（第4卷）》", 30 September 1993, 北京：化学工业出版社 * |
| 王进福等: "基于酚醛树脂的超高比表面积中孔活性炭的研究", 《炭素》 * |
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Application publication date: 20160720 |