CN105749355A - Orthopedic plant endoprosthesis - Google Patents
Orthopedic plant endoprosthesis Download PDFInfo
- Publication number
- CN105749355A CN105749355A CN201610255034.4A CN201610255034A CN105749355A CN 105749355 A CN105749355 A CN 105749355A CN 201610255034 A CN201610255034 A CN 201610255034A CN 105749355 A CN105749355 A CN 105749355A
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- CN
- China
- Prior art keywords
- orthopedic implant
- degradable metal
- layer
- metal material
- endoprosthesis
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
Abstract
The invention relates to an orthopedic plant endoprosthesis which comprises a base, a first layer and a second layer.The first layer covers the base, the second layer covers the first layer, the base comprises organic high-polymer materials, the first layer comprises non-degradable metal materials, and the second layer comprises degradable metal materials.The orthopedic plant endoprosthesis has the advantages that the organic high-polymer materials, the non-degradable metal materials and the degradable metal materials are compounded and shaped to form the orthopedic plant endoprosthesis, effects of friction surfaces of the orthopedic plant endoprosthesis and mechanical bearing effects mainly can be realized by the organic high-polymer material portions of the orthopedic plant endoprosthesis, effects of porous structures capable of accommodating bone ingrowth mainly can be realized by non-degradable metal material portions of the orthopedic plant endoprosthesis, degradable metal material portions of the orthopedic plant endoprosthesis are magnesium or magnesium alloy coatings which cover porous metal surfaces, and a bone induction effect and a sterilization effect mainly can be realized by the degradable metal material portions.
Description
Technical field
The present invention relates to a kind of medical rehabilitation instrument, more particularly, to a kind of orthopedic implant prosthese.
Background technology
Wear-resisting, antibacterial and reduction stress shielding is current orthopaedics particularly artificial joint Primary replacement and overhauls encountered Three Difficult Issues.Traditional orthopedic implant prosthese is individually formed by macromolecular material, metal material or ceramic material substantially, or by macromolecular material and metal material, metal material and ceramic material composite molding.It is replaced into example with artificial hip prosthesis, acetabular cup is mainly added bioceramic material such as hydroxyapatite coating layer by titanium alloy or titanium alloy and forms, friction lining is made up of ultra-high molecular weight polyethylene or aluminium oxide ceramics, friction bulb is made up of vitallium or aluminium oxide ceramics, and joint handle is added hydroxyapatite coating layer by titanium alloy or titanium alloy and forms.The abrasion of articular surface obtains immense success in clinic due to the extensive use of supra polymer height cross-linked material and ceramic-on-ceramic rubbing surface.nullBut antibacterial problem still relies only on antibiotic use，And，Owing to being overly dependent upon rigid material such as metal or pottery as mechanics supporting body，Thus the method that a difficult problem for stress shielding is not solved by all the time，Such as the anti-impact force of pottery and metal is weak、Rigidity is too high and stress shielding problem (BaderR,BergschmidtP,FritscheA,AnsorgeS,ThomasP,MittelmeierW.(2008)Alternativematerialsandsolutionsintotalkneearthroplastyforpatientswithmetalallergy.Orthopade.2008Feb；37(2):136-42；PanegrossiG,CerettiM,PapaliaM,CasellaF,FavettiF,FalezF.(2014)Bonelossmanagementintotalkneerevisionsurgery.IntOrthop.2014Feb；38(2):419-27).
Therefore, a kind of novel and desirable orthopedic implant prosthese that can overcome disadvantages mentioned above is desired.
Summary of the invention
Solve the technical problem that for above-mentioned, it is an object of the invention to provide a kind of orthopedic implant prosthese.
In order to realize foregoing invention, the present invention adopts the following technical scheme that
A kind of orthopedic implant prosthese, including matrix, the ground floor covered on matrix and the cladding second layer on the first layer, wherein matrix is made up of high-molecular organic material, and ground floor is made up of non-degradable metal material, and the second layer is made up of degradable metal material.
Further, high-molecular organic material is ultra-high molecular weight polyethylene or polyether-ether-ketone.
Further, non-degradable metal material is any one in titanium, titanium alloy, tantalum, tantalum alloy, zirconium-niobium alloy, vitallium, stainless steel material.
Further, degradable metal material is magnesium or magnesium alloy.
Further, the surface of ground floor is loose structure.
Further, the second layer is the coating being sprayed on described loose structure surface.
Further, the thickness of coating is less than or equal to 20 microns.
Further, orthopedic implant prosthese is any one in biological fixation acetabular cup, biological fixation femur ankle, biological fixation tibia support, the femur bulb of biological fixation hip joint superficial substitution and biological fixation artificial intervertebral disk.
Owing to adopting above technical scheme, the invention have the benefit that
Orthopedic implant prosthese provided by the invention is by high-molecular organic material, non-degradable metal material and degradable metal Material cladding molding.This prosthese macromolecular material part is made up of polyether-ether-ketone or ultra-high molecular weight polyethylene, non-degradable metal material part is titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or rustless steel, and degradable metal material part is degradable magnesium or magnesium alloy.Macromolecular material part primarily serves rubbing surface and the mechanics carrying effect of prosthese, non-degradable metal material part primarily serves the loose structure effect that can hold Bone Ingrowth, degradable metal material part, for covering porous metals surface magnesium or magnesium alloy coating, primarily serves the dual function of self-bone grafting and sterilizing.Therefore, orthopedic implant prosthese provided by the invention solves current orthopaedics particularly artificial joint Primary replacement and overhauls encountered wear-resisting, antibacterial and reduction stress shielding Three Difficult Issues.
Accompanying drawing explanation
Fig. 1 is an embodiment of orthopedic implant prosthese provided by the invention；
Fig. 2 is another embodiment of orthopedic implant prosthese provided by the invention；
Fig. 3 is the another embodiment of orthopedic implant prosthese provided by the invention；
Fig. 4 is the another embodiment of orthopedic implant prosthese provided by the invention；
Fig. 5 is the another embodiment of orthopedic implant prosthese provided by the invention.
Description of reference numerals
1 acetabular cup, 11 acetabular cup mortar linings, the intermediate layer of 12 acetabular cups, the outermost layer of 13 acetabular cups, 2 femur ankles, 21 matrixes, the intermediate layer of 22 femur ankles, the innermost layer of 23 femur ankles, 3 tibia supports, 31 matrixes, 32 mid portions, 33 lowermost parts, 4 tibial prosthesis, 41 matrixes, 42 mid portions, 43 inner surfaces, 5 artificial intervertebral disks, the outer surface of 51 soleplates, 51' moving part, 52 soleplate tibial side, 53 coatings.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is described in further detail.Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention.
Fig. 1 is the embodiment that orthopaedics provided by the invention is implanted into prosthese.As it is shown in figure 1, orthopedic implant prosthese is biological fixation acetabular cup 1.Acetabular cup 1 includes acetabular cup mortar lining 11, cover on acetabular cup mortar lining 11 the intermediate layer 12 of acetabular cup and the outermost layer 13 of acetabular cup being coated on intermediate layer 12.Wherein, acetabular cup mortar lining 11 is made up of the high-molecular organic material of High molecular weight polyethylene or polyether-ether-ketone；Intermediate layer 12 is titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or stainless steel material, and the outer surface in intermediate layer 12 is loose structure；Outermost layer 13 is for degradable magnesium or magnesium alloy coating, and the thickness of this coating is less than 20 microns.
Fig. 2 is another embodiment of orthopedic implant prosthese provided by the invention.As in figure 2 it is shown, in the present embodiment, orthopedic implant prosthese is biological fixation knee joint femoral ankle 2.The intermediate layer 22 of the femur ankle that femur ankle 2 includes matrix 21 (outer layer of femur ankle), cover on matrix 21 and the innermost layer 23 of femur ankle being coated on intermediate layer 22.Wherein, matrix 1 is by high-molecular organic material, for instance, High molecular weight polyethylene or polyether-ether-ketone are made；Intermediate layer is 22 is non-degradable metal material, for instance titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or stainless steel material, the inner surface in intermediate layer 22 is loose structure；Innermost layer 23 is the coating of degradable metal material such as magnesium or magnesium alloy, and the thickness of this coating is less than 20 microns.
Fig. 3 is another embodiment of orthopedic implant prosthese provided by the invention.As it is shown on figure 3, in the present embodiment, orthopedic implant prosthese is biological fixation knee joint femoral holder 3.Femur holder 3 includes matrix 31 (topmost of tibia support), the mid portion 32 covered on matrix 31 and the lowermost part 33 of tibia support being coated on mid portion 32.Wherein, matrix 31 is made up of the high-molecular organic material of High molecular weight polyethylene or polyether-ether-ketone；Mid portion 32 is non-degradable metal material, for instance, titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or stainless steel material, the lower surface of mid portion 32 is loose structure；Lowermost part 33 is the coating of degradable metal material such as magnesium or magnesium alloy, and the thickness of this coating is less than 20 microns.
Fig. 4 is another embodiment of orthopedic implant prosthese provided by the invention.As shown in Figure 4, in the present embodiment, orthopedic implant prosthese is biological fixation knee joint femoral prosthesis 4.Femoral prosthesis 4 includes matrix 41, cover on matrix 41 mid portion 42 and the inner surface 43 being coated on mid portion 42.Wherein, matrix 41 is high-molecular organic material, for instance High molecular weight polyethylene or polyether-ether-ketone；Mid portion 42 is non-degradable metal material, for instance, titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or stainless steel material, the inner surface of mid portion 42 is loose structure；Inner surface 43 is the coating of degradable metal material such as magnesium or magnesium alloy, and the thickness of this coating is less than 20 microns.
Fig. 5 is another embodiment of orthopedic implant prosthese provided by the invention.As it is shown in figure 5, in the present embodiment, orthopedic implant prosthese is biological fixation artificial intervertebral disk 5.Artificial intervertebral disk 5 comprises soleplate and lower soleplate, and the outer surface 51 of soleplate is by high-molecular organic material, for instance ultra-high molecular weight polyethylene or polyether-ether-ketone are constituted；Moving part 51' between upper and lower soleplate is the friction pair of organic material composition, and the high-molecular organic material wherein constituting 51' is different from the high-molecular organic material constituting 51；The nearly bone side 52 of soleplate is non-degradable metal material, for instance titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or stainless steel material；The surface of this non-degradable metal material part is loose structure, and comprises degradable metal material coating 53 such as magnesium or magnesium alloy coating 53, and the thickness of this coating 53 is less than 20 microns.
Orthopedic implant prosthese provided by the invention is by high-molecular organic material, non-degradable metal material and degradable metal Material cladding molding.The high-molecular organic material of this prosthese is made up of ultra-high molecular weight polyethylene or polyether-ether-ketone, primarily serves prosthese rubbing surface and the effect of part mechanics supporting body；The non-degradable metal material of this prosthese is made up of titanium or titanium alloy, tantalum or tantalum alloy, zirconium-niobium alloy, vitallium or rustless steel, primarily serves and forms the many bore geometries and part mechanics carrying effect holding Bone Ingrowth；The degradable metal material of this prosthese is made up of magnesium or magnesium alloy, and this degradable metal is the coating covering non-degradable metal porous structure surface, and the effect of this coating has induction Bone Ingrowth and antibacterial double effects.
The foregoing is only presently preferred embodiments of the present invention, be not used for limiting the practical range of the present invention；If without departing from the spirit and scope of the present invention, the present invention is modified or equivalent replacement, all should be encompassed in the middle of the protection domain of the claims in the present invention.
Claims (8)
1. an orthopedic implant prosthese, it is characterized in that, including matrix, cover ground floor on the matrix and the cladding second layer on the first layer, wherein said matrix is made up of high-molecular organic material, described ground floor is made up of non-degradable metal material, and the described second layer is made up of degradable metal material.
2. orthopedic implant prosthese according to claim 1, it is characterised in that described high-molecular organic material is ultra-high molecular weight polyethylene or polyether-ether-ketone.
3. orthopedic implant prosthese according to claim 1, it is characterised in that described non-degradable metal material is any one in titanium, titanium alloy, tantalum, tantalum alloy, zirconium-niobium alloy, vitallium, stainless steel material.
4. orthopedic implant prosthese according to claim 1, it is characterised in that described degradable metal material is magnesium or magnesium alloy.
5. orthopedic implant prosthese according to claim 1, it is characterised in that the surface of described ground floor is loose structure.
6. orthopedic implant prosthese according to claim 5, it is characterised in that the described second layer is the coating being sprayed on described loose structure surface.
7. orthopedic implant prosthese according to claim 6, it is characterised in that the thickness of described coating is less than or equal to 20 microns.
8. the orthopedic implant prosthese according to any one of claim 1-7, it is characterized in that, described orthopedic implant prosthese is any one in biological fixation acetabular cup, biological fixation femur ankle, biological fixation tibia support, the femur bulb of biological fixation hip joint superficial substitution, biological fixation artificial intervertebral disk.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610255034.4A CN105749355A (en) | 2016-04-22 | 2016-04-22 | Orthopedic plant endoprosthesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610255034.4A CN105749355A (en) | 2016-04-22 | 2016-04-22 | Orthopedic plant endoprosthesis |
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| CN105749355A true CN105749355A (en) | 2016-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610255034.4A Pending CN105749355A (en) | 2016-04-22 | 2016-04-22 | Orthopedic plant endoprosthesis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106264802A (en) * | 2016-08-05 | 2017-01-04 | 北京爱康宜诚医疗器材有限公司 | Knee-joint prosthesis |
| CN107699860A (en) * | 2017-10-23 | 2018-02-16 | 南昌航空大学 | A kind of preparation method for improving medical porous titanium alloy bioactivity |
| CN114176811A (en) * | 2021-11-15 | 2022-03-15 | 浙江大学 | PEEK base station of nano-needle interface and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1647242B1 (en) * | 2004-10-12 | 2008-05-28 | Benoist Girard Sas | Prosthetic acetabular cups |
| CN202724040U (en) * | 2012-08-08 | 2013-02-13 | 嘉思特华剑医疗器材(天津)有限公司 | Dual coating hip joint prosthesis |
| CN104921845A (en) * | 2015-07-03 | 2015-09-23 | 江苏奥康尼医疗科技发展有限公司 | Bone defect filler |
| CN105030380A (en) * | 2015-05-15 | 2015-11-11 | 江苏奥康尼医疗科技发展有限公司 | Combined artificial hip joint cup |
-
2016
- 2016-04-22 CN CN201610255034.4A patent/CN105749355A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1647242B1 (en) * | 2004-10-12 | 2008-05-28 | Benoist Girard Sas | Prosthetic acetabular cups |
| CN202724040U (en) * | 2012-08-08 | 2013-02-13 | 嘉思特华剑医疗器材(天津)有限公司 | Dual coating hip joint prosthesis |
| CN105030380A (en) * | 2015-05-15 | 2015-11-11 | 江苏奥康尼医疗科技发展有限公司 | Combined artificial hip joint cup |
| CN104921845A (en) * | 2015-07-03 | 2015-09-23 | 江苏奥康尼医疗科技发展有限公司 | Bone defect filler |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106264802A (en) * | 2016-08-05 | 2017-01-04 | 北京爱康宜诚医疗器材有限公司 | Knee-joint prosthesis |
| CN107699860A (en) * | 2017-10-23 | 2018-02-16 | 南昌航空大学 | A kind of preparation method for improving medical porous titanium alloy bioactivity |
| CN114176811A (en) * | 2021-11-15 | 2022-03-15 | 浙江大学 | PEEK base station of nano-needle interface and preparation method thereof |
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