CN105748310A - Synergist, and preparation method and application thereof - Google Patents
Synergist, and preparation method and application thereof Download PDFInfo
- Publication number
- CN105748310A CN105748310A CN201410778954.5A CN201410778954A CN105748310A CN 105748310 A CN105748310 A CN 105748310A CN 201410778954 A CN201410778954 A CN 201410778954A CN 105748310 A CN105748310 A CN 105748310A
- Authority
- CN
- China
- Prior art keywords
- hair
- synergist
- hair dye
- dye
- dyeing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of the cosmetic industry, and concretely relates to a synergist, and a preparation method and an application thereof. The synergist is represented by formula I, and can be used in a hair dye as a hair dyeing synergist. The synergist can be mixed with highly safe European Union approbated food dyes and cosmetic dyes, and substitutes present hair dyes containing genotoxic and carcinogenic allergy p-phenylenediamine, so dyes containing the synergist can be used by people without worrying toxicity or allergy problems. The dyes containing the synergist allow brown black hair to be directly dyed into red hair without bleaching the hair, and have excellent dyeing performance and washing fastness.
Description
Technical field
The invention belongs to cosmetics industry technical field, be specifically related to a kind of synergist and preparation thereof and application.
Background technology
The hair dye accounting for market 80% share at present is p-phenylenediamine class permanent type hair dye, first dose of such hair dye comprises oxidation dye, coupling composition, alkaline matter etc., the Main Ingredients and Appearance of second dose is the hydrogen peroxide of high concentration, hair scale sheet is opened by its dyeing theory with the alkaline matter of first dose, oxidation dye enters cortex of hair layer with coupling composition, the oxidation dye entering cortex of hair layer is carried out oxidation reaction with coupling composition by second dose containing hydrogen peroxide, cortex of hair layer is formed macromole dyestuff, owing to macromole dyestuff cannot pass through narrow and small hair hair scale sheet gap, therefore such hair dye has the washable and fastness to light of excellence.But lot of documents report recently, oxidation dye all has significantly high toxicity with coupling composition such as p-phenylenediamine, resorcinol and has carcinogenic danger, often causes skin to produce anaphylaxis in various degree.Additionally, first dose of alkaline matter used is except having stink, its strong basicity (pH=10-11) meeting heavy losses hair quality, hair is made to tarnish, embrittlement is easily broken, the toxic and side effects of relevant p-phenylenediamine permanent type hair dye and safety problem more and more should be worth the concern of people, and developed country pays much attention to and study the carcinogenecity that this type of hair dye brings already.
For the problem solving p-phenylenediamine class permanent type hair dye health risk, meet consumer's demand to safety non-toxic hair dye, the hair dye manufacturer of China and India releases the botanical hair dye headed by Hai Na, such hair dye dyeing kinetics is slow, in most cases need within several hours, just can complete dyeing, and poor stability, affected greatly by extraneous factor, dye after fastness undesirable in-convenience in use, in addition unresolved toxicity problem.
Nontoxic acid stain, basic stain that European Union is ratified by Japan, Korea S, hair dye research and development institution of Britain are used for hair dye and introduce to the market.ColorRestore, JeromeRussell, Trukolor hair dye of such as Britain, the DARIYA that DARIYA Co., Ltd. of Japan produces is naturally black, DARIYA is dark brown, KAMINOMOTO buttocks Thallus Laminariae (Thallus Eckloniae) naturally black, sharp, Annadonna are blue, Annadonna Fructus Vitis viniferae is red, the JORVES redness hair dye of Korea S.This type of hair dye, without hydrogen peroxide, p-phenylenediamine class material, overcomes p-phenylenediamine class hair dye to the poisonous and hazardous shortcoming of human body.But the dyestuff used by hair dye hardly diffuses to greatly inside hair due to molecular weight, dyeing kinetics is slow, typically require and be heated to more than 40 DEG C, usual more than 40 minutes of dyeing time, and need to dye and repeatedly hair could be dyed color of object, fade and seriously do not reach permanent type effect, in addition the acid stain selected by such hair dye, basic stain all easily pollutes scalp color and not easily goes, and all skin is had coloration, the method solved is to reduce by supplementary means skin is dyeed, as: 1. matched have vaseline oil, it is applied on chignon line before hair dyeing and does bottoming, form a kind of skin care film；2. supporting two kinds of hair dyeing shuttles, one is tiny especially is exclusively used in the dyeing of hair root, to reduce skin dyeing；3. being equipped with the makeup remover being specifically applied to skin dyeing part, dyestuff is washed away by time makeup remover by contamination after skin；Or utilize alkaline soap washing dyeing part.Although utilizing three of the above supplementary means can reduce scalp dyeing, but use very inconvenient, typically require special salon or specialty hairdresser just can complete dyeing, additionally due to the alkalescence of makeup remover or soap relatively strong (pH is typically larger than 10), not only skin being caused stimulation, the skin or the hair that processed dry and astringent simultaneously.Although this type of hair dye is safer, but disadvantages mentioned above limits the popularization of such hair dye.
On market, red hair dye needs to float shallow with oxidizing substances such as hydrogen peroxide by the melanin in black hair in use, in order to demonstrate red effect during hair dyeing.As required, float shallow process to carry out with dyeing course, it is possible to first floated by hair and shallow dye again simultaneously.Covering due to hair dye color, consumer's overview is less than the color after bleaching, but hair will become apparent from out light yellow after the color contaminated is decorporated, owing to destroying the melanin of hair purple in bleaching process, the color after dyeing will be unable to after decorporating return to hair black originally.Cut-off order, it does not have black hair dye can be just redness without bleaching by a kind of business-like hair dye.
Red color tone hair dye more fugitive color compared with other colors, the red dye molecules that reason of fading is formed after being in that dyeing is less than the molecule of other colors, more easily by hair scale sheet gap from hair diffusion inside out, during washing faster than other color fadings, in addition, the red dye molecules that hair dye is formed is easier to by the ultraviolet damage (BouillonC in sunlight, WilkinsonJ.TheScienceofHairCareSecondEdition.CRCpress, BocaRaton, 2005,435).Fading serious, persistency difference is the common problem that red color tone hair dye is urgently to be resolved hurrily.
As described above, it is known that current hair dye all exists respective shortcoming, there is not yet safe to the human body, easy to use, color and persistently and do not pollute the hair dye of scalp.
Summary of the invention
It is an object of the invention to provide the synergist of a kind of novel structure and preparation thereof and application.
For achieving the above object, the present invention adopts the technical scheme to be:
A kind of synergist, synergist is shown in Formulas I,
A kind of preparation method of synergist, reaction equation is as follows:
By cysteine sodium under acid binding agent effect and chloracetyl chloride-10-50 DEG C, between pH=2-10 reaction within 0.5-3 hour, obtain 2-(2-chloracetyl imines)-3-mercaptopropionic acid, then 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea reacted 130 hours at 0-100 DEG C be prepared into synergist 2-shown in Formulas I (2-(carbonamidine sulfydryl) acetamido)-3-mercaptopropionic acid；
Wherein,
The mol ratio of chloracetyl chloride and cysteine sodium, acid binding agent is 1-2:1:1-5；
The mol ratio of 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea is 1:1-2.
Preparation method is preferably, by cysteine sodium under sodium carbonate effect and chloracetyl chloride-5-10 DEG C, between pH=6-8 reaction within 0.5-3 hour, obtain 2-(2-chloracetyl imines)-3-mercaptopropionic acid, then 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea reacted at 10-40 DEG C within 10-12 hour, be prepared into synergist 2-shown in Formulas I (2-(carbonamidine sulfydryl) acetamido)-3-mercaptopropionic acid；
Wherein,
Chloracetyl chloride cysteine sodium, sodium carbonate mol ratio be 1-1.2:1:1-1.2；
2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea mol ratio are 1:1-1.5.
Technical scheme also includes the application of a kind of synergist, and synergist is in hair dye, as hair dyeing synergist.
Synergist is in red hair dye, as hair dyeing synergist.Keratoprotein can be dyeed by described hair dye, such as fingernail, beard, eyebrow etc..
A kind of red hair dye, hair dye is dyestuff, synergist, hair penetrant, diluent, alkaline agent, conditioning composition, thickening agent and surfactant；Wherein by weight percentage, dyestuff 0.01-10%, synergist 0.1-20%, hair penetrant 2-20%, diluent 20-90%, alkaline agent 2-18%, conditioning composition 0.5-10%, thickening agent 0.1-20% and surfactant 0.1-10%.
Hair dye is preferred, by weight percentage, and dyestuff 0.1-5%, synergist 0.5-5%, hair penetrant 1-10%, diluent 70-90%, alkaline agent 2-18%, conditioning composition 0.5-10%, thickening agent 0.5-1.5% and surfactant 0.5-2.5%.
Each composition in hair dye, particularly as follows:
Cosmetics are painted and one or more mixing (referring to following table) in the red solvent dye of food color, carmoisine, rosamines, red pigment in can serve as of ratifying of European Union for the dye source adopted.Dyestuff includes:
Synergist is the hair synergist shown in Formulas I, to open hair scale sheet horny layer, promotes dye molecule can diffuse quickly into inside hair, shortens dyeing time, promotes the washable fastness to light of formula.
Hair penetrant its be hair penetration enhancer and hair extender can improve dyeability, wherein the extender of indication, penetration enhancer can known by the art such as benzyl alcohol, isopropanol, N-N-methyl 2-pyrrolidone N-, acrylic acid carbonic ester, anhydrous sodium sulfate, benzoic acid, carbamide, sodium lauryl sulphate, sarcosyl, glucose, sucrose.
Diluent can comprise one or more solvents.Principal diluent is water, other suitable diluent can be selected from international cosmetic raw material list (INCI list) raw material specified, these solvents can be miscible with water and harmless, it is suitable as diluent of the present invention and also includes C1-C20 monohydric alcohol or polyhydric alcohol and their ether, preferred monohydric alcohol and dihydroxylic alcohols, such as the mixture of ethanol, isopropanol, normal propyl alcohol, butanol, propylene glycol, glycol monoethyl ether and above-mentioned solvent.
Surfactant can comprise one or more, and suitable surfactant can find on INCI list.Surfactant selected by the present invention generally comprises 8-30 carbon atom length, and can be selected from the mixture of anionic surfactant, cationic surface active agent, nonionic surfactant, amphoteric surfactant or above surfactant.
Thickening agent can be the thickening agent for the approval of cosmetics aspect.One or more in oleic acid, hexadecanol, octadecanol, oleyl alcohol, carbomer, xanthan gum, hydroxymethyl cellulose, hydroxyethyl cellulose, carboxymethyl cellulose, carboxyethyl cellulose.
Conditioning composition, to improve the feel of hair after dyeing, makes hair surface smooth, improves the cardability of hair, oils and fats that conditioning composition selects to ratify on INCI list, silicone oil, cationic polymer.Oils and fats includes: n-alkane, isoparaffin, monoesters, dibasic ester, triglyceride, hexadecanol, octadecanol, two Lauryl Alcohols or stearic acid；Silicone oil includes: dimethicone, alkyl-silicone oil, polyether silicone oil, alkyl, polyether silicone oil, amino-silicone, quaternary ammonium salt silicone oil or phenyl silicone oil；Cationic polymer includes: alkyl quaternary ammonium salts, alkylamide, alkylamide quaternary ammonium salt, guar hydroxypropyl trimonium chloride, polyquaternary ammonium salt-6, polyquaternary ammonium salt-7, Polyquaternium-10, polyquaternary ammonium salt-37, polyquaternary ammonium salt-39, polyquaternary ammonium salt-47, Polyquaternium-67, quaternized hydrolyzed protein or quaternized starch.
Alkaline agent can make hair soften, and alkaline agent includes one or more of compositions: ornithine, arginine, lysine, ammonia, monoethanolamine, diethanolamine, triethanolamine, alkylolamides, sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate, sodium bicarbonate, potassium bicarbonate etc..
The pH value range of above-mentioned hair dye is between 3.5-11, it is preferable that between 3.5-9.5.It is conventional acid or alkali in order to regulate the reagent of hair coloring preparation composition, wherein acid optimization citric acid, lactic acid, tartaric acid, acetic acid；The preferred sodium hydroxide of alkali, ammonia, triethylamine, ethanolamine, triethanolamine, 2-amino-2-methyl-1-propanol, the consumption of acid or alkali is determined according to the pH value reached needed for actual formula.
Except mentioned component, when not damaging effect of the present invention, can add and use other compositions of the side of generally using in hair dye, such as, specifiable such as cationic surfactant, anion surfactant, nonionic surfactant, amphoteric surfactant, lanolin derivative, protein derivatives, oils and fats, fat, polyhydroxy-alcohol, ester, amide, wetting agent composition, Chinese medicine extract composition, gelling thickener, low-carbon alcohols solvent, vitamin, aminoacid, preservative, antibacterial, pH adjusting agent, penetrating agent, ultraviolet absorber, antioxidant, coloring agent, antioxidant, spice etc..
Described hair dye can be made into cream rinse, hair dye emulsion, hair dyeing frost, hair dye gel, hair dyeing shampoo, foam type hair dye or spray-type hair-dyeing agent.
Described hair dye prepares into one dosage type low temperature or two-form hair dye.
When using above-mentioned hair dye to have hair dyed, temperature range is 10-50 DEG C, it is preferable that 25-35 DEG C, and the too low Color of temperature is undesirable, and uncomfortable sensation is implemented and scalp is caused to too high being not easy to of temperature.Dyeing time 10-50 minute, it is preferable that 10-30 minute, the color depth that can reach as required specifically adjusts dyeing time.
First with Hair-dyeing brush, hair dye is applied on hair uniformly during hair dyeing, places 15-25 minute in room temperature, with tap water once, then remove remaining hair dye with shampoo washing, dry by hair dryer or in room temperature with hair-dryer.
Described hair dye can be used for the stain of beard, eyebrow or fingernail.
Advantage for present invention:
The present invention have hair dyed synergist (Formulas I) colorless and odorless and food dye, dyestuff used for cosmetic composite go out safety non-toxic hair dye, optionally coloring hairs is not infected with scalp, there is dyeability and the fastness to washing of excellence.
Amido and imido grpup are contained in booster molecules one end of the present invention simultaneously, the protein of hair is had very big affinity and is rich in permeability, and booster molecules of the present invention can also form hydrogen bond with dye molecule, inside dye molecule " being transported to " hair, therefore synergist makes dye molecule diffusion rate in hair apparently higher than the osmosis on skin, and then reduces skin dyeing.It addition, sulfydryl is contained in molecule one end, it is possible to open hair scale under the premise not damaging hair quality, synergism is played in the diffusion accelerating dye molecule.Synergist of the present invention is to hair not damaged, and the solution of high-load is also unlikely to make hair scale come off, and Long contact time is also nontoxic.
The food dye ratified with the European Union of high security by synergist of the present invention, the synthetic dyestuffs being used for cosmetics mix as hair dye, hair dye of the present invention instead of the hypersensitive p-phenylenediamine case hair dye of genotoxicity, carcinogenecity at present, human body uses no longer to be worried during hair dye of the present invention to can be applicable to toxicity and anaphylaxis problem containing cuticular hair, beard, eyebrow, fingernail etc..Hair dye provided by the invention has exceeded the standard of hair dye in the market, including washability, persistency, convenience, rapidity, particularly in just hair color not being dyed redness under the premise of black bleached hair.
Being had hair dyed by the present invention, synergist composite acquisition hair dye is easy to use, color lasting, oxide-free matter, Color are good.Following advantage is possessed compared with commercially available hair dye:
(1) hair dye of the present invention is the nontoxic acid stain of consumer goods committee of European Union annotation, solvent dye, pigment, basic stain, food dye substituted p-phenylenediamine class oxidation dye, and it solves existing hair dye because of the global problem of the potential sensitization brought containing the material such as p-phenylenediamine, resorcinol, carcinogenic, mutagenic action.
(2) hair dye formulas provided by the present invention is without oxidation materials such as hydrogen peroxide, oxidation bleaching effect is there is not during dyeing, when not changing black hair background color, it is dyed redness, owing to hair black pigment not being damaged, by reduction hair black originally after the color contaminated is decorporated, this is that on market, red permanent hair dye cannot be accomplished.
(3) hair dye formulas provided by the invention has the incomparable fastness to washing of market redness hair dye and fastness to light, hair after dyeing washs without discolouration phenomena through 30 times, after volunteer's hair dyeing, color is able to maintain that five months, and after dyeing with market redness hair dye, color generally persistently has clear superiority compared with in the of about 40 days.
(4) present invention furthers investigate the composition of protein in scalp and hair, utilize synergist of the present invention change dyestuff migration rate on skin and hair, when solving the dyestuffs such as current acid stain, solvent dye, pigment, basic stain, food coloring for hair dye enemy's leather dyeing seriously, not easy cleaning, inconvenient problem with use.
(5) formula that hair dye of the present invention provides can complete dyeing in gentle when, and the time completed dyeing, dyeing temperature 20-30 DEG C in 10-20 minute.
Detailed description of the invention
Synergist prepares example:
Embodiment 1
The synthetic route of Formulas I synergist is as follows:
Under room temperature, 14.3g (0.1mol) cysteine sodium is dissolved in 100ml water, it is cooled to less than 0 DEG C with ice-water bath, dropping 12.4g (0.11mol) chloracetyl chloride, it is simultaneously added dropwise 60g sodium carbonate liquor (0.1mol) that mass fraction is 17.6%, maintain pH between 7-8, time for adding about 30 minutes, reaction 3 hours it is stirred for after dropwising, then room temperature it is warmed up to, it is gradually added thiourea 7.6g (0.1mol), within 10 minutes, add complete, continue stirring 12 hours, the white solid powder precipitated out is filtered, and use 100ml water washing, dry and obtain synergist shown in 21.2g Formulas I, yield 89.4%.Synergist spectrum data shown in Formulas I is: and 1H-NMR (400MHz, CDCl3) δ: 1.5 (1H, s), 2.93-3.18 (2H, m), 3.76 (2H, m), 4.78 (1H, m), 8.32 (1H, s), and 9.27-9.29 (3H, m), 12.57 (1H, s).
Embodiment 2
Under room temperature, 28.6g (0.2mol) cysteine sodium is dissolved in 150ml water, it is cooled to less than 5 DEG C with ice-water bath, dropping 33.8g (0.3mol) chloracetyl chloride, it is simultaneously added dropwise 168g sodium carbonate liquor (2.4mol) that mass fraction is 15%, maintain pH between 6-7, time for adding about 50 minutes, reaction 2.5 hours it is stirred for after dropwising, then 40 DEG C it are warmed up to, it is gradually added thiourea 22.8g (0.3mol), within 20 minutes, add complete, continue stirring 15 hours, the white solid powder precipitated out is filtered, and use 100ml water washing, dry and obtain synergist shown in 45.06g Formulas I, yield 95.0%.Synergist spectrum data shown in Formulas I is: and 1H-NMR (400MHz, CDCl3) δ: 1.5 (1H, s), 2.93-3.18 (2H, m), 3.76 (2H, m), 4.78 (1H, m), 8.32 (1H, s), and 9.27-9.29 (3H, m), 12.57 (1H, s).
The configuration embodiment of hair dye
Involved by following hair dye except synergist, all reagent derive from commercially available.
Embodiment 1, solvent dye are used as formula (one dosage type low temperature hair dye)
Each composition such as following table in formula:
| Material name | Percentage by weight (%) |
| Solvent red 3 | 0.5 |
| Ethanol | 10.0 |
| Glucose | 5.0 |
| Synergist shown in Formulas I | 1.0 |
| Xanthan gum | 1.5 |
| Hexadecanol | 1.5 |
| Oleic acid | 5.0 |
| Disodium EDTA | 0.5 |
| Citric acid | 1.0 |
| Triethanolamine | 3.0 |
| Spice | 0.1 |
| Water | Surplus |
According to hair colouring methods described below, formula in embodiment 1 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 2, solvent red dye are used as formula (two component hair dyes)
Each composition such as following table in formula:
| Material name | First dose of percentage by weight (%) | Second dose of percentage by weight (%) |
| Solvent red 3 | 0.5 | |
| Ethanol | 10.0 | |
| Glucose | 5.0 | |
| Synergist shown in Formulas I | 1.0 |
| Xanthan gum | 0.5 | 0.5 |
| Octadecanol | 1.0 | 0.5 |
| Oleic acid | 3.0 | 2.0 |
| Disodium EDTA | 0.5 | 0.5 |
| Citric acid | 1.0 | 1.5 |
| Sodium hydroxide | 1.0 | 2.0 |
| Spice | 0.1 | 0.1 |
| Water | Surplus | Surplus |
According to hair colouring methods described below, formula in embodiment 2 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 3, pigment are used as hair dye (one dosage type low temperature hair dye)
Each composition such as following table in formula:
| Material name | Percentage by weight (%) |
| Paratonere 7 | 0.1 |
| Ethanol | 5.0 |
| Glucose | 1.0 |
| Synergist shown in Formulas I | 2.0 |
| Carbopol 940 | 0.5 |
| Polyoxyethylene ether | 13.0 |
| Oleic acid | 5.0 |
| Disodium EDTA | 0.5 |
| Citric acid | 2.0 |
| Monoethanolamine | 3.0 |
| Spice | 0.1 |
| Water | Surplus |
According to hair colouring methods described below, formula in embodiment two being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 4, pigment are used as hair dye (two component hair dyes)
Each composition such as following table in formula:
According to hair colouring methods described below, formula in embodiment 4 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 5, acid stain are used as hair dye (one dosage type low temperature hair dye)
Each composition such as following table in formula:
| Material name | Percentage by weight (%) |
| Azogeramine 4 | 0.4 |
| Ethanol | 5.0 |
| Glucose | 1.0 |
| Synergist shown in Formulas I | 2.0 |
| Xanthan gum | 0.5 |
| Hexadecanol | 1.5 |
| N-Methyl pyrrolidone | 5.0 |
| Glycerol | 5.0 |
| Disodium EDTA | 0.5 |
| Citric acid | 1.0 |
| Triethanolamine | 3.0 |
| Spice | 0.2 |
| Water | Surplus |
According to hair colouring methods described below, formula in embodiment 5 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 6, acid stain are used as hair dye (two component hair dyes)
Each composition such as following table in formula:
According to hair colouring methods described below, formula in embodiment 6 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 7, food dye are used as hair dye (one dosage type low temperature hair dye)
Each composition such as following table in formula:
| Material name | Percentage by weight (%) |
| Food Red 17 | 1.0 |
| Ethanol | 10.0 |
| Glucose | 1.0 |
| Synergist shown in Formulas I | 2.0 |
| Hydroxyethyl cellulose | 1.5 |
| Hexadecanol | 1.5 |
| Oleic acid | 10.0 |
| Disodium EDTA | 0.5 |
| Citric acid | 1.0 |
| Triethanolamine | 3.0 |
| Spice | 0.2 |
| Water | Surplus |
According to hair colouring methods described below, formula in embodiment 7 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
Embodiment 8, food dye are used as hair dye (two component hair dyes)
Each composition such as following table in formula:
| Material name | First dose of percentage by weight (%) | Second dose of percentage by weight (%) |
| Food Red 17 | 0.3 | |
| Ethanol | 5.0 | |
| Glucose | 1.0 | |
| Synergist shown in Formulas I | 1.0 | |
| Hydroxyethyl cellulose | 1.0 | 0.5 |
| Hexadecanol | 1.0 | 1.0 |
| Oleic acid | 3.0 | 3.0 |
| Disodium EDTA | 0.5 | 01.0 |
| Citric acid | 1.0 | 1.5 |
| Triethanolamine | 2.0 | 2.0 |
| Spice | 0.2 | 0.1 |
| Water | Surplus | Surplus |
According to hair colouring methods described below, formula in embodiment 8 being carried out dye test, hair used is untreated brownish black hair, and Color is estimated according to method as described below.
The various embodiments described above configuration being obtained hair dye dye in the following manner, the effect after hair dyeing is estimated simultaneously, concrete hair colouring methods and evaluation criteria are as follows:
The use of one dosage type low temperature hair dye: the one dosage type low temperature hair dye 2.5g of above-mentioned offer is applied on the hair of 5.0g length 15 centimetres uniformly with Hair-dyeing brush, stop 15-20 minute in room temperature, with Warm Wash decaptitate send out on hair dye, then with shampoo clean namely complete hair dyeing.
The use of two component hair dyes: being mixed the first of above-mentioned offer dose, second dose with mass ratio 1:2 ratio, it is standby to stir, take the mixed hair dye of 2.5g and be applied on the hair of 5.0g length 15 centimetres uniformly, stop 15-20 minute in room temperature, with Hair-dyeing brush, mixed hair dye is applied on hair uniformly, stop 15-20 minute in room temperature, with Warm Wash decaptitate send out on hair dye, then with shampoo clean namely complete hair dyeing.
Hair dye Color appraisal procedure: the indexs such as degree that wash away after the smooth degree of hair, skin dyeing after the colouring power of hair dye, color durability and dyeing are graded by the hair swatch after dyeing according to unified standard by 10 professional hairdressers.
Colouring power appraisal procedure: immediately with warm water washing after being dyeed 20 minutes by Hair grooming hair dye, after flushing again with the shampoo solution washing of 5% concentration once, after blower fan dries up, allow 10 professional hairdressers that hair colouring degree after dyeing to be graded.
Hair feel after dyeing: immediately with warm water washing after being dyeed 20 minutes by Hair grooming hair dye, after flushing again with the shampoo solution washing of 5% concentration once, after drying up with blower fan, allow 10 professional hairdressers that the feel on hair after dyeing is commented grading；
Fastness to washing after dyeing: immediately with warm water washing after Hair grooming hair dye is dyeed 20 minutes, after flushing again with the shampoo solution washing of 5% concentration once, after drying up with blower fan, again with the shampoo solution washing of 5% concentration, dry up with blower fan, after iterative cycles 30 times, 10 professional hairdressers hair bleaching degree before and after washing is graded；
Complexity is washed away: be applied on arm skin by 0.5g hair dye after skin contamination, smear radius 1.0 centimetres, stop 15 minutes on arm under room temperature, graded by 10 professional hairdressers after tap water, if clear water cannot wash away, washing with the suds of 5% concentration, be again evaluated by 10 professional hairdressers after washing, average after statistics.
Rating scale is following table such as
Comparative example 1
Brownish black hair, white hair are dyeed and be estimated according to Color appraisal procedure according to above-mentioned colouring method by red hair dye ColorRestore respectively that buy from Britain.
Comparative example 2
Brownish black hair, white hair are dyeed and be estimated according to Color appraisal procedure according to above-mentioned colouring method by Fructus Vitis viniferae red hair dye Annadonna respectively that buy from Japanese market.
The hair dye of the present invention above-mentioned hair dye embodiment configuration and market purchased from hair dye colouring power test result such as following table:
Remarks *: light yellow hair is to utilize dual oxide by the light yellow hair that obtains after shallow for the drift of brownish black hair
Result from table it can be seen that
(1) red hair dye formulas provided by the invention can by Chinese brownish black hair under the premise without bleaching directly dye be redness, after dyeing color persistently, be smooth to the touch, be very easy to wash away to after skin dyeing.
(2) English market is bought red hair dye ColorRestore and the red hair dye Annadonna of Fructus Vitis viniferae that Japanese market is bought can not manifest Color on after brownish black hair-dyeing owing to being affected by hair background color, hair after dyeing is still brownish black, must be floated by hair color by salon stylist and shallow just can dye before brownish black hair-dyeing.
(3) compared with the red hair dye Annadonna of Fructus Vitis viniferae of English market redness hair dye ColorRestore and Japanese market, after hair dye formulas provided by the invention dyeing, color is more lasting, skin will not be caused dyeing.
Claims (10)
1. a synergist, it is characterised in that: synergist is shown in Formulas I,
2. the preparation method of the synergist described in a claim 1, it is characterised in that: reaction equation is as follows:
By cysteine sodium under acid binding agent effect and chloracetyl chloride-10-50 DEG C, between pH=2-10 reaction within 0.5-3 hour, obtain 2-(2-chloracetyl imines)-3-mercaptopropionic acid, then 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea reacted 130 hours at 0-100 DEG C be prepared into synergist 2-shown in Formulas I (2-(carbonamidine sulfydryl) acetamido)-3-mercaptopropionic acid；
Wherein,
The mol ratio of chloracetyl chloride and cysteine sodium, acid binding agent is 1-2: 1: 1-5；
The mol ratio of 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea is 1: 1-2.
3. by the preparation method of the synergist described in claim 2, it is characterized in that: by cysteine sodium under sodium carbonate effect and chloracetyl chloride-5-10 DEG C, between pH=6-8 reaction within 0.5-3 hour, obtain 2-(2-chloracetyl imines)-3-mercaptopropionic acid, then 2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea reacted at 10-40 DEG C within 10-12 hour, be prepared into synergist 2-shown in Formulas I (2-(carbonamidine sulfydryl) acetamido)-3-mercaptopropionic acid；
Wherein,
Chloracetyl chloride cysteine sodium, sodium carbonate mol ratio be 1-1.2: 1: 1-1.2；
2-(2-chloracetyl imines)-3-mercaptopropionic acid and thiourea mol ratio are 1: 1-1.5.
4. the application of the synergist described in a claim 1, it is characterised in that: synergist is in hair dye, as hair dyeing synergist.
5. by the application of the synergist described in claim 4, it is characterised in that: synergist is in red hair dye, as hair dyeing synergist.
6. a red hair dye, it is characterised in that: hair dye contains dyestuff, synergist, hair penetrant, diluent, alkaline agent, conditioning composition, thickening agent and surfactant；Wherein by weight percentage, dyestuff 0.01-10%, synergist 0.1-20%, hair penetrant 2-20%, diluent 20-90%, alkaline agent 2-18%, conditioning composition 0.5-10%, thickening agent 0.1-20% and surfactant 0.1-10%.
7. by the red hair dye described in claim 6, it is characterized in that: by weight percentage, this redness hair dye contains dyestuff 0.1-5%, synergist 0.5-5%, hair penetrant 1-10%, diluent 70-90%, alkaline agent 2-18%, conditioning composition 0.5-10%, thickening agent 0.5-1.5% and surfactant 0.5-2.5%.
8. by the red hair dye described in claim 6 or 7, it is characterised in that: described hair dye can be made into cream rinse, hair dye emulsion, hair dyeing frost, hair dye gel, hair dyeing shampoo, foam type hair dye or spray-type hair-dyeing agent.
9. by the red hair dye described in claim 8, it is characterised in that: described hair dye prepares into one dosage type low temperature or two-form hair dye.
10. by the red hair dye described in claim 8, it is characterised in that: described hair dye can be used for the stain of beard, eyebrow or fingernail.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410778954.5A CN105748310B (en) | 2014-12-15 | 2014-12-15 | A kind of synergist and its preparation and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410778954.5A CN105748310B (en) | 2014-12-15 | 2014-12-15 | A kind of synergist and its preparation and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105748310A true CN105748310A (en) | 2016-07-13 |
| CN105748310B CN105748310B (en) | 2018-08-24 |
Family
ID=56336771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410778954.5A Active CN105748310B (en) | 2014-12-15 | 2014-12-15 | A kind of synergist and its preparation and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105748310B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068930A (en) * | 2010-08-17 | 2013-04-24 | 巴斯夫欧洲公司 | Disulfide or thiol polymeric hair dyes |
-
2014
- 2014-12-15 CN CN201410778954.5A patent/CN105748310B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068930A (en) * | 2010-08-17 | 2013-04-24 | 巴斯夫欧洲公司 | Disulfide or thiol polymeric hair dyes |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105748310B (en) | 2018-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1306924C (en) | Two-part aqueous composition for oxidative coloration of hair | |
| KR101363383B1 (en) | Hair dye, dyeing hair product combination and its use method | |
| CN101175535B (en) | Permanent waving agent | |
| CN101528192A (en) | Use of natural dyes for dying human hair | |
| KR20110122742A (en) | A mordant and hair dyeing products containing the same | |
| DE3824122A1 (en) | METHOD FOR COLORING KERATINIC FIBERS WITH AT LEAST ONE DYE OF THE INDOLE RANGE | |
| CN105992583A (en) | Process for dyeing keratin materials using powder from indigo-producing plants and alkaline agent(s) | |
| JPH05339134A (en) | Hair dye | |
| JP2007119480A (en) | Hair-dyeing agent composition and method for producing the same | |
| DE3028131A1 (en) | HAIR DYE | |
| JP4815626B1 (en) | Hair dye | |
| Wall | Bleaches, hair colorings, and dye removers | |
| CN101820856B (en) | Non-oxidative hair dye composition | |
| RU2493814C1 (en) | Composition for hair dyeing | |
| US7578857B1 (en) | Color shampoo formula | |
| JP4287719B2 (en) | Hair dye and hair dyeing method using the same | |
| CN105748310B (en) | A kind of synergist and its preparation and application | |
| KR100884894B1 (en) | Composition of hairdye and method of manufacturing thereof | |
| CN114668681A (en) | Keratin fiber dyeing composition and dyeing method | |
| JPH10182374A (en) | Hair dye composition | |
| JPH11158049A (en) | Hair dye composition | |
| JPH11199445A (en) | Hair cosmetic | |
| JP7430386B2 (en) | Oxidized hair dye first agent | |
| KR100844228B1 (en) | Composition of hairdye and method of manufacturing thereof | |
| KR102086071B1 (en) | Hair-dye product |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |