CN105738432B - Blood sugar test paper hydrophilic film stable and reliable for performance - Google Patents
Blood sugar test paper hydrophilic film stable and reliable for performance Download PDFInfo
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- CN105738432B CN105738432B CN201610058104.7A CN201610058104A CN105738432B CN 105738432 B CN105738432 B CN 105738432B CN 201610058104 A CN201610058104 A CN 201610058104A CN 105738432 B CN105738432 B CN 105738432B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/401—Salt-bridge leaks; Liquid junctions
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Abstract
The invention discloses a kind of blood sugar test paper hydrophilic film stable and reliable for performance, the blood sugar test paper includes test paper body, forms the polyester film of the test paper body base material and be coated on the hydrophilic film of the polyester film surface, it is characterised in that：The hydrophilic film ethanol solution is dissolved in by fatty alcohol polyoxyethylene ether after, by being attached to the polyester film surface after being coated with drying tunnel drying and forming.The hydrophilic film of the present invention, does not have glue solid fraction powder or particle when cutting or rolling cut, will not produce the hidden danger for blocking hydrophilic film sample holes on blood sugar test paper；Moreover, the hydrophilic film of the present invention, ageing resistance and homogeneity are greatly enhanced.
Description
Technical field
The present invention relates to blood sugar test paper, especially a kind of hydrophilic film stable and reliable for performance on blood sugar test paper.
Background technology
According to the sound of China《National news are broadcasted》Report, cut-off on November 15th, 2013 " world's diabetes day ", China's sugar
Urine patient's number is up to 1.14 hundred million, is also being increased every year with 1.5% speed.Therefore, as one kind have concurrently medical instrument and
The blood glucose high speed tester of consumer electronic product, is widely used in the detection and analysis to blood glucose.The test of blood glucose high speed tester
Principle is：Apply certain constant voltage at the blood sugar test paper electrode both ends of insertion blood glucose high speed tester（Such as 300mV）, work as quilt
After survey blood sample sucks electrode working zone by the hydrophilic film on blood sugar test paper, the glucose oxidase in test paper electrode surface workspace
Redox reaction occurs with the glucose in blood sample, after quick biochemical reaction, the response that enzyme electrode test paper produces is electric
Stream（About between 0.1~10 μ A）It is in a linear relationship with concentration of glucose in tested blood sample, it is single in blood glucose high speed tester
The size of blood sample response current is detected under the control of piece machine, so that accurate blood glucose concentration value be calculated and quickly surveyed in blood glucose
Try instrument liquid crystal screen display final result.
Any type blood sugar test paper all can't do without following main component：Oxidoreducing enzyme（Such as glucose oxidase, Portugal
Grape sugar-NAD-dehydrogenase, glucose-PQQ-dehydrogenase and glucose-FAD-dehydrogenase etc.）, various conducting mediums（As benzoquinones,
The potassium ferricyanide, ferrocene, ruthenium compound, osmium compound etc.）, and binder（As hydroxyethyl cellulose, carboxymethyl cellulose,
Stabilizer of surfactant and enzyme and conductive agent etc.）.Table 1 lists domestic and international more commonly used blood sugar test paper at present and makes
Base stock.
Table 1
| Test paper base material | Binder | Conductive agent | Reagent enzyme | Surfactant |
| PET | Hydroxyethyl cellulose | 1,4-benzoquinone | Glucose oxidase | Qula is led to |
| PP | Carboxymethyl cellulose | The potassium ferricyanide | Glucose dehydrogenase | Soil temperature |
| PC | Collagen | Ferrocene | Glucokinase | DOW CORNING defoamer |
| PVC | Seaweed acid gel | Metallic conduction compound | Fluorine class surfactant |
In blood sugar test paper, influence accuracy of detection in addition to mentioned component, also have one layer of crucial material, here it is parent
Moisture film.When tested blood sample is dropped on blood sugar test paper, drop of blood can quickly be spread and suck electrode working zone by hydrophilic film, with true
Protect the progress of blood sugar test.Its essence of hydrophilic film is exactly polyester film（PET) surface is coated with hydrophilic substance, in the prior art,
Hydrophilic film is coated with using thermoplastic hydrophilic material（Hydrophilic substance is dissolved in solvent-based thermal plastic material, by being coated with drying tunnel drying parent
Water substance adheres to pet sheet face in the case where thermoplastic matchmaker connects）, so as to reach hydrophilic effect.This hydrophilic film, hydrophilic substance with
Colloidal solid form is present in pet sheet face, and bulk hydrophilic film is being cut into the parent that can be positioned in blood glucose high speed tester
During moisture film bar, inevitably have glue solid fraction powder or particle produces, these glue solid fraction powder or particle can be in cut-off knives（Or rolling
Knife）Blade at accumulate, if cleaning not in time, these cementation sprills or particle fall on hydrophilic film bar, will direct shadow
Detection result and precision are rung, causes unqualified generation.
The content of the invention
The object of the present invention is to provide the preferable and stable and reliable for performance blood sugar test paper use of a kind of anti-aging property, homogeneity
Hydrophilic film.
To achieve the above object, the present invention adopts the following technical scheme that：
A kind of blood sugar test paper hydrophilic film stable and reliable for performance, the blood sugar test paper include test paper body, form the examination
The polyester film of hard copy body base material and the hydrophilic film for being coated on the polyester film surface, it is characterised in that：The hydrophilic film is by fat
Alcohol polyoxyethylene ether be dissolved in ethanol solution after, by being coated be attached to the polyester film surface after drying tunnel drying and form.
In the ethanol solution of the fatty alcohol polyoxyethylene ether, the weight percent content of fatty alcohol polyoxyethylene ether is 1-
3%。
PE films are compounded with the hydrophilic film.
Compared with prior art the beneficial effects of the invention are as follows：Due to the adoption of the above technical scheme, the hydrophilic film is by fat
Fat alcohol polyoxyethylene ether be dissolved in ethanol solution after, by being coated be attached to the polyester film surface after drying tunnel drying and form, should
Oily matter does not have the generation of glue solid fraction material, when making hydrophilic film bar is cut or roller is cut, does not just have glue solid fraction powder or particle
Produce, without clearing up blade, the hidden danger for blocking hydrophilic film sample holes on blood sugar test paper will not be produced；Moreover, the present invention's is hydrophilic
Film, ageing resistance and homogeneity are greatly enhanced.
Brief description of the drawings
Fig. 1 is the structure diagram of the present invention.
Embodiment
As shown in Figure 1, the present invention is a kind of blood sugar test paper hydrophilic film stable and reliable for performance, the blood sugar test paper includes
Test paper body 1, the polyester film 101 for forming 1 base material of test paper body and the hydrophilic film 2 for being coated on 101 surface of polyester film,
The hydrophilic film 2 ethanol solution is dissolved in by fatty alcohol polyoxyethylene ether after, by be coated with after drying tunnel drying be attached to it is described poly-
101 surface of ester film is formed.Preferably, in the ethanol solution of the fatty alcohol polyoxyethylene ether, fatty alcohol polyoxyethylene ether
Weight percent content is 1-3%, and the optimal weight percent content 3% of fatty alcohol polyoxyethylene ether, this ratio can be true
Protecting hydrophilic film 2 has optimal effect.In order to be protected in blood sugar test paper using preceding to hydrophilic film 2, in the hydrophilic film 2 also
Can be with compound PE film 3.
It is the hydrophily and ageing resistance experimental result to hydrophilic film of the present invention below；
Sample message：132mm wide * 100m long, no PE films.Volume 1, single side is hydrophilic.
Experimental method：
Received sample hydrophilic film is opened in clean area packing workshop and cuts into the current specification of production, then aritificial cut-off
Into 6mm wide * 5cm long, dispensed with drying bottle.Before test, with drying bottle take a part of hydrophilic film be placed on test between constant temperature 30
More than minute, contact angle test is pressed《Hydrophilic film examination criteria》The test method test of middle contact angle, remaining hydrophilic film are placed on
Aging in 60 DEG C of baking ovens, extracts weekly the test of part hydrophilic film once later, and (adhesivesresearch, is shown in existing AR
Www.adhesivesresearch.com) hydrophilic film contrasts.
As can be seen from the above table：The contact angle of the present invention and the deviation of maxima and minima are slightly larger than AR when unaged
Hydrophilic film, but contact angle after AR hydrophilic film agings and when unaged differ larger and maxima and minima deviation also compared with
Greatly, the anti-aging property and homogeneity for illustrating the present invention are better than AR hydrophilic films.
Compared with the AR hydrophilic films of import, the price of every square metre of the present invention is less than its half, and current market accounts for
There is rate steadily improving.
Claims (3)
1. a kind of blood sugar test paper hydrophilic film stable and reliable for performance, the blood sugar test paper includes test paper body（1）, form the examination
Hard copy body（1）The polyester film of base material（101) and it is coated on the polyester film（101）The hydrophilic film on surface（2）, it is characterised in that：
The hydrophilic film（2）After being dissolved in ethanol solution by fatty alcohol polyoxyethylene ether, by be coated with after drying tunnel drying be attached to it is described
Polyester film（101）Surface is formed.
2. blood sugar test paper hydrophilic film stable and reliable for performance according to claim 1, it is characterised in that：The fatty alcohol
In the ethanol solution of polyoxyethylene ether, the weight percent content of fatty alcohol polyoxyethylene ether is 1-3%.
3. blood sugar test paper hydrophilic film stable and reliable for performance according to claim 1 or 2, it is characterised in that：Described
Hydrophilic film（2）On be compounded with PE films（3）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610058104.7A CN105738432B (en) | 2016-01-27 | 2016-01-27 | Blood sugar test paper hydrophilic film stable and reliable for performance |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610058104.7A CN105738432B (en) | 2016-01-27 | 2016-01-27 | Blood sugar test paper hydrophilic film stable and reliable for performance |
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| Publication Number | Publication Date |
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| CN105738432A CN105738432A (en) | 2016-07-06 |
| CN105738432B true CN105738432B (en) | 2018-05-11 |
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| CN201610058104.7A Active CN105738432B (en) | 2016-01-27 | 2016-01-27 | Blood sugar test paper hydrophilic film stable and reliable for performance |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109453675A (en) * | 2018-12-19 | 2019-03-12 | 杭州快诊新材料科技有限公司 | Two-sided hydrophilic film coating system |
| CN109453677A (en) * | 2018-12-19 | 2019-03-12 | 杭州快诊新材料科技有限公司 | The manufacturing method of two-sided hydrophilic film |
| CN112162095A (en) * | 2020-09-24 | 2021-01-01 | 上海印标包装有限公司 | Hydrophilic film and manufacturing method thereof |
| CN114414560A (en) * | 2021-12-30 | 2022-04-29 | 广东环凯生物技术有限公司 | Test paper for measuring total chlorine, preparation method thereof and method for rapidly measuring total chlorine |
| CN116087286A (en) * | 2023-03-10 | 2023-05-09 | 上海微创生命科技有限公司 | Biosensor and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1867407A (en) * | 2003-10-17 | 2006-11-22 | 3M创新有限公司 | Surfactant composition having stable hydrophilic character |
| CN101246175A (en) * | 2007-02-14 | 2008-08-20 | 胡军 | Silk screen printing method for producing blood sugar test paper |
| CN101303358A (en) * | 2007-05-10 | 2008-11-12 | 胡军 | Siphoning type blood sugar test paper |
| CN104007255A (en) * | 2014-05-16 | 2014-08-27 | 中南林业科技大学 | Aflatoxin B1 rapid detection test paper strip and preparation method and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2402759B1 (en) * | 2010-06-29 | 2014-02-26 | Actherm Inc. | Testing strip for detecting a fluidic sample |
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2016
- 2016-01-27 CN CN201610058104.7A patent/CN105738432B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1867407A (en) * | 2003-10-17 | 2006-11-22 | 3M创新有限公司 | Surfactant composition having stable hydrophilic character |
| CN101246175A (en) * | 2007-02-14 | 2008-08-20 | 胡军 | Silk screen printing method for producing blood sugar test paper |
| CN101303358A (en) * | 2007-05-10 | 2008-11-12 | 胡军 | Siphoning type blood sugar test paper |
| CN104007255A (en) * | 2014-05-16 | 2014-08-27 | 中南林业科技大学 | Aflatoxin B1 rapid detection test paper strip and preparation method and application thereof |
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| CN105738432A (en) | 2016-07-06 |
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