CN105709123A - 一种治疗由痰湿内阻所致高血压的中药组合物 - Google Patents

一种治疗由痰湿内阻所致高血压的中药组合物 Download PDF

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CN105709123A
CN105709123A CN201610312646.2A CN201610312646A CN105709123A CN 105709123 A CN105709123 A CN 105709123A CN 201610312646 A CN201610312646 A CN 201610312646A CN 105709123 A CN105709123 A CN 105709123A
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鞠衍松
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Abstract

本发明涉及中药技术领域。本发明的目的是针对由痰湿内阻所致高血压的特点，通过辩证分析，进而提供一种治疗该症的中药组合物，采用下列重量配比的原料药物组合而成：薏苡仁1020份、桃仁515份、白术1020份、红花515份、甘草39份、石决明1020份、大枣515份、五味子1020份、代赭石1020份、巴戟天515份、磁石515份、琥珀515份、远志515份、附子39份、钩藤515份、厚朴1525份、芡实1020份、茯苓1020份、鸡血藤515份、肉桂515份、山茱萸1020份、川芎515份。该中药组合物在药物选用上虽然为常用药物，但通过对病症准确的辩证分析，将常规药物进行合理配伍，斟酌用量，其能取得令人满意的治疗效果。

Description

一种治疗由痰湿内阻所致高血压的中药组合物
技术领域
本发明涉及中药技术领域，具体是指一种治疗由痰湿内阻所致高血压的中药组合物。
背景技术
高血压在中医领域原本没有固定的概念，多是将高血压病的一些症状分属于眩晕、头痛、中风等疾病中。现代中医将高血压病分为肝阳上亢型、阴虚阳亢型、阴阳两虚型、痰湿中阻型等多种证型，诊断治疗方法复杂，并且受西医的影响较重，大部分是针对该病的症状的治疗，难以发挥中医治本的优势。在高血压病的辩证中，由痰湿内阻所致高血压的病例不为少见，主要由于现代人嗜食肥甘、活动量降低造成，主要表现为苔腻黄，脉弦、滑，头晕目眩，健忘耳鸣，失眠多梦等，治疗时常见的药物有白术、半夏、天麻等健脾化湿、化痰熄风的药物。采用上述药物及疗法有时确能取得疗效，但部分患者受药治疗效果较差，而外在症状又表现为典型的痰湿中阻，由此在治疗由痰湿内阻所致高血压时仍需辩证分析，对症施药。 发明内容
本发明的目的是针对由痰湿内阻所致高血压的特点，通过辩证分析，进而提供一种治疗该症的中药组合物。
为实现上述技术目的，本发明采用的技术方案为：一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁10-20份、桃仁5-15份、白术10-20份、红花5-15份、甘草3-9份、石决明10-20份、大枣5-15份、五味子10-20份、代赭石10-20份、巴戟天5-15份、磁石5-15份、琥珀5-15份、远志5-15份、附子3-9份、钩藤5-15份、厚朴15-25份、芡实10-20份、茯苓10-20份、鸡血藤5-15份、肉桂5-15份、山茱萸10-20份、川芎5-15份。
一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁15g、桃仁10g、白术15g、红花10g、甘草6g、石决明15g、大枣10g、五味子15g、代赭石15g、巴戟天10g、磁石10g、琥珀10g、远志10g、附子6g、钩藤10g、厚朴20g、芡实15g、茯苓15g、鸡血藤10g、肉桂10g、山茱萸15g、川芎10g。
本发明所提供的中药组合物的服用方法为：将上述重量配比的原料药物混合后采用常规煎制中药的方法取其药汁300-500ml，每日早晚两次服用，每日一副。
组方分析：由痰湿内阻所致高血压以风痰相搏为主要病机，痰湿为标，脾虚为本，治法为健脾化痰，定眩息风固不为错，在本发明所提供的中药组合物中取白术、薏苡仁、茯苓、厚朴、甘草、大枣泄湿培中、健脾益气，代赭石、钩藤、磁石、石决明平肝熄风。但细究之，头晕目眩、失眠多梦等症多与肝风内动有关，中焦土败，则肝木不升，郁而化风，肝郁过久则必致血瘀，因此在平肝息风的同时需加以化瘀之药，如该中药组合物中的鸡血藤、桃仁、红花、川芎；而人体三气本于一气，肾气为其根本，中焦脾气衰败，根源于肾气之衰，也因此造成由痰湿内阻所致高血压多发于中老年患者之由，以老年肾气衰退，脾气必弱，因此补脾气时需兼顾下焦肾气，加以附子、肉桂、巴戟天回补肾阳；肾气衰败则致精水不藏，精水不藏则肾阳无所依，故取芡实、五味子、山茱萸固精止带；取琥珀、远志镇静安神，清其上焦发散之火。由此可见，在治疗由痰湿内阻所致高血压时，单纯的健脾化痰、定眩熄风可能能够暂时取得疗效，但是对部分患者而言，痰湿中阻有其生痰之源，如肾气衰败，有痰湿内阻所生旁症，如血瘀，针对上述情形，在治疗由痰湿内阻所致高血压时需通盘考虑。本发明所提供的中药组合物通过对原料中药的精选配合，达到健脾化痰、定眩熄风的同时，补肾气、化血瘀、固其精、安其神的效果，从根本上消除痰湿中阻的发病之源及衍生之症，从而可获得良好的治疗效果。该中药组合物在药物选用上虽然为常用药物，但通过对病症准确的辩证分析，将常规药物进行合理配伍，斟酌用量，其能取得令人满意的治疗效果。
具体实施方式
下面结合实施例对本发明所提供的中药组合物做进一步说明。
实施例1
一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁15g、桃仁10g、白术15g、红花10g、甘草6g、石决明15g、大枣10g、五味子15g、代赭石15g、巴戟天10g、磁石10g、琥珀10g、远志10g、附子6g、钩藤10g、厚朴20g、芡实15g、茯苓15g、鸡血藤10g、肉桂10g、山茱萸15g、川芎10g。
本发明人对本实施例中所提供的中药组合物进行了临床观察试验，试验如下：
(1) -般资料
筛选由痰湿内阻所致高血压患者44例，血压平均值为：低压109毫米汞柱、高压146毫米汞柱，其中男性患者24例，女性患者20例，最小年龄41岁，最大年龄71岁，平均年龄53岁，患者典型症状表现为：尺脉沉细无力、关脉弦、滑，纳食差、眩晕耳鸣、头目胀痛，急躁易怒，心悸健忘，失眠多梦等。
(2)治疗方法：服用本实施例所提供的中药组合物，每日早晚两次服用，每日一副，7日为一疗程。
(3)疗效评定标准
治愈：舒张压降至89毫米汞柱以下、收缩压降至139毫米汞柱以下，停药1个月以上血压无大的升幅。
有效：舒张压及收缩压相对服药前数值有所下降。
无效：舒张压及收缩压数值无变化或持续升高。
（4）试验结果
服药一周后，有23例患者的血压值出现下降，其中8例患者的血压值进入正常值范围，继续服药两周后测试，共有36例患者的血压值出现不同程度下降，其中30例患者的血压值进入正常值范围，继续服用两周，共有37例患者的血压值进入正常值范围，4例患者的血压值出现下降，3例患者无改变。3个月后跟踪测试，37例正常值患者中，无血压值升高，血压值仍处于正常值范围。统计表明，该中药组合物对治疗由痰湿内阻所致高血压具有显著的治疗效果，其治愈率达到84.09%、有效率达93.18%以上。
典型病例
1、汤某，女，59岁，高血压病史2年，舒张压108毫米汞柱、收缩压162毫米汞柱，期间服用过多种西药控制血压，但降压效果一直不明显，患者表现为易躁易怒，眩晕耳鸣，健忘，纳食差，舌滑多津液，脉弦、滑，诊断为由痰湿内阻所致高血压。
治疗方法：在服用已有降压药物的同时服用本实施例所提供的中药组合物，服用1周后，病人自感眩晕耳鸣症状减轻，纳食有所改善，血压测试，舒张压99毫米汞柱，收缩压152毫米汞柱，停掉其他药物，继续服用该中药组合物1周，再测血压，舒张压降至96毫米汞柱，收缩压降至145毫米汞柱，继续服用两周，再测，舒张压降至88毫米汞柱，收缩压降至136毫米汞柱，为巩固疗效，继续服用两周后停药，舒张压降至85毫米汞柱，收缩压维持136毫米汞柱。停药3个月内，患者无眩晕、健忘等症状出现，纳食恢复正常，测血压值，舒张压及收缩压都维持在正常值范围内，患者得以彻底康复。
2、江某，男，62岁，高血压病史4年，舒张压115毫米汞柱、收缩压168毫米汞柱，期间一直服用过丹参片、卡托普利、代文等血压控制药物，在患病期间表现为易躁易怒，不思饮食，全身无力，舌滑多津，不思水饮，尺脉沉细无力，关脉滑，诊断为肾气衰败导致的由痰湿内阻所致高血压。
治疗方法：在服用已有降压药物的同时服用本实施例所提供的中药组合物，服用2周后，病人自感情绪平稳，能够控制情绪，进食量增加，血压测试，舒张压106毫米汞柱，收缩压158毫米汞柱，停掉其他药物，继续服用该中药组合物3周，再测血压，舒张压降至95毫米汞柱，收缩压降至145毫米汞柱，为巩固疗效，继续服用两周后停药，舒张压降至88毫米汞柱，收缩压降至138毫米汞柱。停药3个月内，患者无躁怒，头目胀痛等症状出现，进食恢复正常，测血压值，舒张压及收缩压都维持在正常值范围内，患者得以彻底康复。
实施例2
一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁10份、桃仁15份、白术10份、红花15份、甘草3份、石决明20份、大枣5份、五味子20份、代赭石10份、巴戟天15份、磁石5份、琥珀15份、远志5份、附子9份、钩藤5份、厚朴25份、芡实10份、茯苓20份、鸡血藤5份、肉桂15份、山茱萸10份、川芎15份。
实施例3
一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁20份、桃仁5份、白术20份、红花5份、甘草9份、石决明10份、大枣15份、五味子10份、代赭石20份、巴戟天5份、磁石15份、琥珀5份、远志15份、附子3份、钩藤15份、厚朴15份、芡实20份、茯苓10份、鸡血藤15份、肉桂5份、山茱萸20份、川芎5份。

Claims (2)

1.一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁10-20份、桃仁5-15份、白术10-20份、红花5-15份、甘草3-9份、石决明10-20份、大枣5-15份、五味子10-20份、代赭石10-20份、巴戟天5-15份、磁石5-15份、琥珀5-15份、远志5-15份、附子3-9份、钩藤5-15份、厚朴15-25份、芡实10-20份、茯苓10-20份、鸡血藤5-15份、肉桂5-15份、山茱萸10-20份、川芎5-15份。
2.根据权利要求1所述的一种治疗由痰湿内阻所致高血压的中药组合物，其特征在于，该中药组合物是采用下列重量配比的原料药物组合而成：薏苡仁15g、桃仁10g、白术15g、红花10g、甘草6g、石决明15g、大枣10g、五味子15g、代赭石15g、巴戟天10g、磁石10g、琥珀10g、远志10g、附子6g、钩藤10g、厚朴20g、芡实15g、茯苓15g、鸡血藤10g、肉桂10g、山茱萸15g、川芎10g。
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