CN105698934B - The color collecting device of reagent strip - Google Patents
The color collecting device of reagent strip Download PDFInfo
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- CN105698934B CN105698934B CN201610169758.7A CN201610169758A CN105698934B CN 105698934 B CN105698934 B CN 105698934B CN 201610169758 A CN201610169758 A CN 201610169758A CN 105698934 B CN105698934 B CN 105698934B
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 111
- 239000011159 matrix material Substances 0.000 claims abstract description 22
- 238000005259 measurement Methods 0.000 claims abstract description 16
- 239000011248 coating agent Substances 0.000 claims abstract description 11
- 238000000576 coating method Methods 0.000 claims abstract description 11
- 238000001514 detection method Methods 0.000 claims description 30
- 230000004044 response Effects 0.000 claims description 8
- 230000003287 optical effect Effects 0.000 claims description 7
- 239000011521 glass Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 3
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 30
- 239000000126 substance Substances 0.000 abstract description 18
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract description 15
- 239000000084 colloidal system Substances 0.000 abstract description 12
- 239000010931 gold Substances 0.000 abstract description 12
- 229910052737 gold Inorganic materials 0.000 abstract description 12
- 238000009434 installation Methods 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 16
- 210000002700 urine Anatomy 0.000 description 10
- 238000010586 diagram Methods 0.000 description 8
- 238000011161 development Methods 0.000 description 5
- 238000002965 ELISA Methods 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005670 electromagnetic radiation Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000000644 propagated effect Effects 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 230000008054 signal transmission Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000003491 array Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000004251 human milk Anatomy 0.000 description 1
- 235000020256 human milk Nutrition 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- 230000005622 photoelectricity Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/46—Measurement of colour; Colour measuring devices, e.g. colorimeters
- G01J3/50—Measurement of colour; Colour measuring devices, e.g. colorimeters using electric radiation detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to the color collecting device of reagent strip, including the display device being installed in main body, contact-type image sensor and stage carrier, contact-type image sensor includes sensor support body, sensor circuit board is provided with the top of sensor support body, photodiode array is installed below sensor circuit board, filter coating is provided with below photodiode array, line focus camera lens is provided with below filter coating, light emitting diode matrix is provided with least on one side in linear amasthenic lens, the lower surface installation cover plate of sensor support body, plane and cover plate plane are in predetermined angle where light emitting diode matrix；Stage carrier is located at the lower section of contact-type image sensor, and it has objective table sliding groove, and objective table sliding groove is provided with stage guide, and objective table is slidably mounted in objective table sliding groove, and objective table is provided with article putting groove.The color collecting device of the reagent strip can realize the measurement to dry chemical method reagent strip and colloid gold reagent bar.
Description
Technical field
The invention belongs to the color acquisition technology to reagent strip.More particularly to a kind of color collecting device of reagent strip.
Background technology
The color of reagent strip is identified only by human eye, the degree of accuracy is not high, generally requires by instrument and equipment pair
Reagent strip is detected.In the prior art, for the detection of dry chemistry reagent bar, typically it is irradiated with spot light, passes through band
The photodiode for having colour filter carries out color acquisition, if detection many index, drive mechanism is needed to use, by the shifting put
It is dynamic to form linear scanning.
It is irradiated to using the white light that spot light is sent by the light hole of surface integral instrument in reagent strip, reagent strip is anti-light
It is mapped in surface integral instrument and passes through colour filter, obtain the monochromatic light of specific wavelength, be irradiated on photodiode, realizes that photoelectricity turns
Change.
A project can only be detected every time, must then be adopted for the reagent strip 50 (such as 10,11 etc., urine) of more color lumps
With drive mechanism, such as Fig. 1 concrete structure can be used, be driven reagent strip or be driven optical system, therefore add
Cost and unreliability；
And currently used reagent strip, including dry chemical method reagent strip and colloid gold reagent bar, the knot of both reagent strips
Structure is as shown in Figures 2 and 3.Dry chemical method reagent strip includes plastic base 51, reacts color lump 52, holds region 53.Collaurum tries
Agent bar includes base band 57, and hand-held region 53 is set in base band 57, compares thick stick 54, tests thick stick 55, sample infiltration area 56.
But above-mentioned reagent strip detection method, it is only suitable for detecting dry chemical method reagent strip, is not suitable for colloid gold reagent bar.
As shown in figures 4 a and 4b, due to be spot light detection, and single photodiode detection either CCD
(Charge-coupled Device, Chinese full name：Charge coupled cell) imaging sensor, therefore the area of detection zone 58 compared with
Greatly, diameter 3mm border circular areas is can be usually reached, this color acquisition is relatively adapted to color lump (5x5mm) on urine reagent bar
Color acquisition, but the color for being detrimental to 3x1mm collaurum color development area (either compare thick stick 54 or test thick stick 55) is adopted
Collection.If adopted in such a way, the base band color in border circular areas is mixed into, causes the inaccuracy of detection, also therefore
Chemical method can not be synthesized in an equipment with the detection of colloidal gold method.
The content of the invention
The present invention is overcomes technical problem present in prior art to provide the color collecting device of reagent strip, the reagent
The color collecting device of bar can realize the measurement to dry chemical method reagent strip and colloid gold reagent bar.
A kind of color collecting device of reagent strip, including be installed in main body display device, contact-type image sensor,
Control circuit and stage carrier, wherein,
Contact-type image sensor includes sensor support body, and sensor circuit board is provided with the top of sensor support body, passes
The lower surface of sensor circuit board is provided with photodiode array, and the lower surface of photodiode array is provided with filter coating, filter
Line focus camera lens is provided with below light film, light emitting diode matrix is provided with least on one side in linear amasthenic lens,
Photodiode array, light emitting diode matrix, line focus camera lens are installed on sensor support body, under sensor support body
Surface is provided with the cover plate for protecting photodiode array, line focus camera lens and light emitting diode matrix, lights
Plane and cover plate plane are in predetermined angle where diode array；
Stage carrier is located at the lower section of contact-type image sensor, and it has objective table sliding groove, objective table sliding groove
Stage guide is provided with, objective table is slidably mounted in objective table sliding groove, and objective table is provided with horizontal positioned for accommodating
The article putting groove of reagent strip, and the depth of article putting groove is more than the thickness of reagent strip, to cause the upper surface of reagent strip positioned at protection glass
Cover plate is not contacted below glass and；
The light that the light emitting diode matrix is sent is irradiated to the upper surface of reagent strip through cover plate, after reflecting
Cover plate is again passed through, and after the focusing of line focus camera lens and the optical filtering of filter coating, projects the photodiode
Array, photodiode array convert optical signals to electric signal and are delivered to sensor circuit board, and sensor circuit board will be believed
Control circuit number is delivered to, control circuit carries out colorimetric, and measurement result is shown in display device.
And photodiode array is set, the accuracy of detection to single luminous point can be improved, from original single luminous point
Interference can be introduced, becomes a reagent bandwidth, multiple test points is still available for and is detected, error signal will not be produced with selection
Point as measured value so that the detection to colloid gold reagent bar becomes possibility.Moreover, for common dry chemical method reagent
Bar, it can also realize while detect multiple color lumps, also need reagent strip and objective table to be moved in the prior art so as to avoid
Caused reliability is low and the problem of kinematic accuracy difference.
Multiple projects can be disposably detected as a result of photodiode array, and light emitting diode matrix.Employ
Contact-type image sensor, linearity test length can disposably detect the multiple projects related to urine up to more than 90mm, because
This equipment also reduces equipment cost without drive mechanism, improves reliability, moreover, the step of also simplify detection,
Improve detection efficiency；
As a result of line acquisition method, can be set as resolution is 100DPI, i.e., can in 25.4mm length
100 available points are detected, being converted into every 1mm length there are 4 test points.For collaurum (enzyme linked immunosorbent assay) reagent strip, it is aobvious
Color region is 3x1mm strip, using 100DPI contact-type image sensor, in 1mm width, can also be read
Go out 4 test points, also disclosure satisfy that the color acquisition of colloid gold reagent bar.Even if the point for excluding 1mm both ends is likely to occur single-point
Interior half is reagent strip substrate, and half is the erroneous point of color development area, and it is available point that also can at least have 2 points.Can fully it detect
To the color development area of colloid gold reagent bar.Therefore this method is both adapted to chemical method reagent strip, is adapted to collaurum (enzyme linked immunosorbent assay) examination again
The detection of agent bar.
Preferable technical scheme, its additional technical feature are：The bottom of main body is provided with least two and is used to place and determines
The support supporting plate of position stage carrier, the upper surface of each support supporting plate are parallel with the lower surface of cover plate and with preventing
It is equidistant to protect lower glass surface.
By two support supporting plates equidistant with cover plate lower surface, to ensure under stage carrier and cover plate
Surface is parallel, and then ensures that the reagent strip on objective table and objective table is parallel with cover plate, particularly for reagent strip
Color lump contaminated situation, can avoid the dirt contamination on color lump to cover plate, so as to ensure the clear of cover plate
It is clean.
Further preferred technical scheme, its additional technical feature are：Display device is touch-screen, touch-screen and control
Circuit electrically connects, and touch-screen is used to select the species of detection project and detected reagent strip for user and shows measurement result.
By setting touch-screen, testee can be caused, selection test event is needed according to oneself, and show survey
Test result.
Technical scheme still further preferably, its additional technical feature are：Measurement result is converted to bar by control circuit
Shape code or Quick Response Code, and show on the display apparatus.
After the measurement has been completed, Quick Response Code or bar code can also be generated on the touchscreen, swept by intelligent mobile terminal
Retouch the Quick Response Code or bar code, the APP on intelligent mobile terminal decodes to the Quick Response Code or bar code, and soft by APP
Part recorded in intelligent mobile terminal.Avoid and propagated using wireless signal, for user, particularly pregnant woman or quasi- pregnant woman
Caused by electromagnetic radiation.Simultaneously for this mode of wire transmission information, set without in harvester
Put the hardware such as special information transmission circuit or socket.The circuit structure of system is simplified, reduces hardware cost.
Further preferred technical scheme, its additional technical feature are：One end for going deep into stage carrier of objective table
Locating dowel is provided with, locating dowel is used for the bullet with being arranged on stage carrier when objective table is put into color collecting device
Property self-fastening button is engaged to realize the positioning of objective table.
By the combination of locating dowel and elastic self-fastening button, objective table can be accurately positioned, to ensure the accuracy of measurement,
Nor the angle of color collecting device can be limited in measurement, even if color collecting device has tilted, will not also cause
Objective table skids off from stage carrier.Moreover, objective table is promoted again, you can releasing locating dowel is matched somebody with somebody with elastic self-fastening button
Close, it is convenient to take out objective table, reagent strip is changed, cleans objective table.
Further preferred technical scheme, its additional technical feature are：One end for going deep into stage carrier of objective table
Flexible self-fastening button is set, is provided with locating dowel on position corresponding with the elastic self-fastening button on stage carrier, the locating dowel
Carried for being engaged when objective table is put into color collecting device with the elastic self-fastening button being arranged on objective table with realizing
The positioning of thing platform.
By the combination of locating dowel and elastic self-fastening button, objective table can be accurately positioned, to ensure the accuracy of measurement,
Nor the angle of color collecting device can be limited in measurement, even if color collecting device has tilted, will not also cause
Objective table skids off from stage carrier.Moreover, objective table is promoted again, you can releasing locating dowel is matched somebody with somebody with elastic self-fastening button
Close, it is convenient to take out objective table, reagent strip is changed, cleans objective table.
Preferable technical scheme, its additional technical feature are：Plane where light emitting diode matrix is put down with cover plate
Face is into 30 ° of angles.
By by the angle of light emitting diode matrix be arranged to 30 ° of horizontal plane angle, can improve focus point with focus on
The distance between camera lens, in order to cause reagent strip not to be close on cover plate, light can also accurately project surface
Color lump or colour band and reflex on line focus camera lens, to be received by light emitting diode, and be converted into electric signal transmission to control
Circuit processed is handled.The reagent strip surface attachment dirt such as urine faced especially suitable for the application, if directly adopted
Measured with touch sensor, the contaminated situation in cover plate surface can be caused.
Preferable technical scheme, its additional technical feature are：The bottom of article putting groove and the distance of cover plate lower surface
Thickness than the color lump position of reagent strip is big 1-1.5mm.
Applicant shows by many experiments, when the color lump position of reagent strip is placed at into cover plate bottom surface 1-
During 1.5mm, irradiation of the maximally effective realization of light emitting diode matrix to color lump position can be made, meanwhile, color lump portion can be avoided
The dirt of position, pollutes cover plate.Furthermore, it is possible in effective time of measuring, the steam ascension of dirt is avoided to protection
On glass, in case steam contamination is to cover plate.Meanwhile make equipment more accurate to the color detection of reagent strip.
Brief description of the drawings
Fig. 1 is the structural representation of traditional detection means detection chemical method reagent strip mentioned in background technology：
Fig. 2 is the schematic diagram of the dry chemical method reagent strip mentioned in background technology；
Fig. 3 is the schematic diagram of the colloid gold reagent bar mentioned in background technology；
Fig. 4 a and Fig. 4 b are the color lump and colloid using the detection means measurement dry chemical method reagent strip of prior art respectively
The structural representation of the colour band of gold reagent bar；
Fig. 5 is that the objective table of embodiment 1 places the schematic perspective view after upper dry chemical method reagent strip：
Fig. 6 is the sectional view of the objective table of embodiment 1；
Fig. 7 is the schematic perspective view of stage carrier；
Fig. 8 is schematic perspective view of the stage carrier from another angle；
Fig. 9 is the structural representation of the touch sensor in embodiment 1；
Figure 10 is the schematic diagram after objective table, stage carrier are all installed in main body by embodiment 1；
Figure 11 is the schematic diagram observed with Figure 10 with opposite viewing angle；
Schematic diagram after Figure 12 embodiments 1 touch-screen, keycap are installed in main body；
Figure 13 is that the structural representation after battery is installed in embodiment 1.
Embodiment
In order to further understand the content, features and effects of the present invention, hereby enumerating following examples, and describe in detail
It is as follows：
Embodiment 1：
Fig. 5 is that the objective table of embodiment 1 places the schematic perspective view after upper dry chemical method reagent strip：Fig. 6 is embodiment 1
The sectional view of objective table；Fig. 7 is the schematic perspective view of stage carrier；Fig. 8 is stage carrier from another angle
Schematic perspective view；Fig. 9 is the structural representation of the touch sensor in embodiment 1；Figure 10 is embodiment 1 by objective table, carried
Thing platform support be all installed in main body after schematic diagram；Figure 11 is the schematic diagram observed with Figure 10 with opposite viewing angle；Figure
Schematic diagram after 12 embodiments 1 touch-screen, keycap are installed in main body；Figure 13 is after installing battery in embodiment 1
Structural representation.
In figure, the expression implication of each reference is as follows：
10th, main body；20th, contact-type image sensor；30th, stage carrier；40th, objective table；50th, reagent strip；60th, control
Circuit；70th, touch-screen；80th, keycap；90th, rechargeable battery；
11st, support supporting plate；13rd, support installation base；19th, battery guide rail；21st, sensor support body；22nd, light emitting diode
Array；23rd, line focus camera lens；24th, filter coating；25th, photodiode array；26th, sensor circuit board；27th, binding post；
28th, cover plate；34th, stage guide；41st, locating dowel；69th, line three-way hole is crossed.
A kind of color collecting device of reagent strip, including contact-type image sensor 20, contact-type image sensor 20 wrap
Sensor support body 21 is included, the top of sensor support body 21 is provided with sensor circuit board 26, the upper surface of sensor circuit board 26
Provided with binding post 27, the lower surface of sensor circuit board 26 is provided with photodiode array 25, photodiode array 25
Lower surface is provided with filter coating, and line focus camera lens 23 is provided with below filter coating, in the one side of linear amasthenic lens 23
Light emitting diode matrix 22 is provided with, the angle of light emitting diode matrix 22 and horizontal plane is 30 °, photodiode array 25,
Light emitting diode matrix 22, line focus camera lens 23 are installed on sensor support body 21, the lower surface peace of sensor support body 21
Equipped with the cover plate 28 for protecting photodiode array 25, line focus camera lens 23 and light emitting diode matrix 22, light
The focal length of the setting angle of electric diode array 25 and light emitting diode matrix 22, position and line focus camera lens 23 is used to protect
Card focus point is located in the range of 1~1.5mm of the lower section of cover plate 28；
The lower section of contact-type image sensor 20 is provided with stage carrier 30, and stage carrier 30 slides with objective table
Groove, objective table sliding groove are provided with stage guide 34, objective table 40 are slidably fitted with objective table sliding groove, objective table 40
Upper surface middle part is provided with article putting groove, and article putting groove is used to keep flat detected reagent strip 50 to cause at the upper surface of reagent strip 50
In the range of 1~1.5mm of the lower section of cover plate 28.
By by light emitting diode be angle be arranged to 30 ° of horizontal plane angle, focus point and amasthenic lens can be improved
The distance between, in order to cause the reagent strip 50 not being close on cover plate 28, light can accurately project surface
Color lump or colour band and reflex on line focus camera lens 23, to be received by light emitting diode, and be converted into electric signal transmission to
Control circuit 60 is handled.The surface attachment dirt of reagent strip 50 faced especially suitable for the application, directly using existing
Common contact-type sensor in technology measures, and can cause the contaminated situation in the surface of cover plate 28.
And photodiode array 25 is set, the accuracy of detection to single luminous point can be improved, from original single light
Point can introduce interference, become a reagent bandwidth, and being still available for multiple test points is detected, and wrong letter will not be produced with selection
Number point as measured value so that the detection to colloid gold reagent bar becomes possibility.Moreover, for common dry chemical method reagent
Bar, can also realize while detect multiple color lumps, also need reagent strip and objective table 40 to move in the prior art so as to avoid
The problem of moving low caused reliability and kinematic accuracy difference.
Particularly, touch sensor is arranged in main body 10, and the bottom of main body 10 is provided with least two and is used to place
And the support supporting plate 11 of positionable stage support 30, the following table of the upper surface of each support supporting plate 11 with cover plate 28
Face is parallel and equidistant with the lower surface of cover plate 28.
By two support supporting plates 11 equidistant with the lower surface of cover plate 28, to ensure stage carrier 30 and protection
The lower surface of glass 28 is parallel, and then ensures that the reagent strip 50 on objective table 40 and objective table 40 is parallel with cover plate 28, especially
It is in the contaminated situation of the color lump for reagent strip 50, dirt contamination on color lump can be avoided to cover plate 28,
So as to ensure the cleaning of cover plate 28.
Further particularly, touch-screen 70 is also equipped with main body 10, touch-screen 70 electrically connects with control circuit 60, touches
Screen 70 is touched to be used to show measurement result and select detection project and the species of detected reagent strip for user.
By setting touch-screen 70, testee can be caused, selection test event is needed according to oneself, and show
Test result.After the measurement has been completed, Quick Response Code or bar code can also be generated on touch-screen 70, by intelligent mobile terminal Lai
Scanning the Quick Response Code or bar code, the APP on intelligent mobile terminal decodes to the Quick Response Code or bar code, and by APP
Software records are into intelligent mobile terminal.Avoid and propagated using wireless signal, for user, particularly pregnant woman or accurate pregnant
Electromagnetic radiation caused by woman, while also simplify the structure of color collecting device.
Further particularly, one end for going deep into stage carrier 30 of objective table 40 is provided with locating dowel 41, locating dowel
41 are used to setting with the elastic self-fastening button on stage carrier 30 match when objective table 40 is put into color collecting device
Close to realize that the intermittent of objective table 40 positions, intermittence positioning is after objective table 40 is positioned, again to color collecting device
Objective table 40 is promoted, objective table 40 can be caused to be in the state that can be directly taken out, the front end of locating dowel 41 is to remove tip
Arrow-shaped, the shape can coordinate with elastic self-fastening button, realize the positioning of objective table 40.
By the combination of locating dowel 41 and elastic self-fastening button, objective table 40 can be accurately positioned, to ensure the standard of measurement
True property, nor the angle of color collecting device can be limited in measurement, even if color collecting device has tilted, also will not
Objective table 40 is caused to be skidded off from stage carrier 30.Moreover, objective table 40 is promoted again, you can release locating dowel 41 and elasticity
The cooperation of self-fastening button, it is convenient to take out objective table 40, change reagent strip 50 and objective table 40.
The assembly method of the color collecting device of mentioned reagent bar is as follows：
It will be fixed between main body 10 and contact-type image sensor 20 by screw hole；
The support that stage carrier 30 screws in main body 10 by screw is arranged in boss 13, and is entered by support supporting plate 11
Row is fixed；By the objective table 40 for being placed with reagent strip by the stage guide 34 on stage carrier, stage carrier 30 is inserted
Using cable connection control circuit 60 and touch-screen 70；
Keycap 80 is installed on the switch key in insertion control circuit 60；
Control circuit 60 is enclosed in main body 10, passed through by screw on touch-screen 70 by 4 vias in main body 10
Connection through hole 17 realizes the fixation of touch-screen 70 and main body 10；
Positioned between rechargeable battery 90 and main body 10 by battery guide rail 19；
Line three-way hole 69 is crossed through in main body 10, is inserted by cable, cable between rechargeable battery 90 and control circuit 60
Enter in control circuit 60.
After said process has been carried out, screw can also be coordinated by screwed hole, shell is installed in main body.
It is as follows using the reagent strip color acquisition method of above-mentioned color collecting device：
Reagent strip step is placed, the reagent strip 50 after tested sample will be had leached into, be placed on objective table 40；
Objective table step is placed, by the objective table 40 for being placed with reagent strip 50 by stage guide 34, inserts objective table branch
Frame 30；
Start step, the keycap 80 of the color collecting device for opening and closing reagent strip is pressed, opens color acquisition
Device so that all operations are carried out by touch-screen 70；
Measuring process, operation is measured according to the prompting on touch-screen 70；
Lumination of light emitting diode, the upper surface that light is irradiated to reagent strip through cover plate 28 is reflected, and wears again
Cover plate 28 is crossed, is projected by the focusing of line focus camera lens 23, and by the optical filtering of filter coating in photodiode, light
Color signal is simultaneously delivered to control circuit 60 by electric diode, is carried out A/D conversions, is compared by the CPU in control circuit 60
Color method contrast, obtain reagent strip) on each project signal component value, signal component value is shown on touch-screen 70 and shown；
Step is taken out, after detection, presses objective table 40 again, the outer end of objective table 40 outwards leans out, then pulled out again
Go out objective table 40..
Multiple projects can be disposably detected as a result of photodiode array 25, and light emitting diode matrix 22.Adopt
With contact-type image sensor 20, linearity test length can be detected disposably related to urine multiple up to more than 90mm
Project, therefore equipment is without drive mechanism, while equipment cost is also reduced, reliability is improved, moreover, also simplify detection
The step of, improve detection efficiency；
As a result of line acquisition method, can be set as resolution is 100DPI, i.e., can in 25.4mm length
100 available points are detected, being converted into every 1mm length there are 4 test points.For collaurum (enzyme linked immunosorbent assay) reagent strip, it is aobvious
Color region is 3x1mm strip, using 100DPI contact-type image sensor, in 1mm width, can also be read
Go out 4 test points, also disclosure satisfy that the color acquisition of colloid gold reagent bar.Even if the point for excluding 1mm both ends is likely to occur single-point
Interior half is reagent strip substrate, and half is the erroneous point of color development area, and it is available point that also can at least have 2 points.Can fully it detect
To the color development area of colloid gold reagent bar.Therefore this method is both adapted to chemical method reagent strip, is adapted to collaurum (enzyme linked immunosorbent assay) examination again
The detection of agent bar.
Using the device, the corresponding reagent strip of many kinds of substance can be detected：
By in the urine detection reagent strip of dry chemical method (11 or 10 functions) immersion urine specimen, put after taking-up
After entering objective table 40, stage carrier 30, start-up circuit detection so that contact-type image sensor 20 enters to reagent strip 50 are pushed into
Row color acquisition, colorimetric is then carried out by software, draw the diagnostic value of Related Component in urine.
The reagent strip of the onset of ovulation of colloidal gold method is immersed into urine specimen, after objective table 40 is put into after taking-up, is pushed into loading
Platform support 30, start-up circuit detection so that contact-type image sensor 20 carries out color acquisition to reagent strip 50, by test
Bar and the color contrast for compareing thick stick, draw the diagnostic value of Related Component in reagent strip.
The pregnancy reagent strip of colloidal gold method is immersed into urine specimen, after objective table 40 is put into after taking-up, is pushed into objective table branch
Frame 30, start-up circuit detection so that contact-type image sensor 20 to reagent strip 50 carry out color acquisition, by reference test bar with
The color contrast of thick stick is compareed, draws the diagnostic value of Related Component in reagent strip.
Detected for the breast milk nutritional ingredient after pregnant, it is identical with above-mentioned first method using dry chemical method reagent.
Although the preferred embodiments of the present invention are described above in conjunction with accompanying drawing, the invention is not limited in upper
The embodiment stated, above-mentioned embodiment is only schematical, be not it is restricted, this area it is common
Technical staff in the case of present inventive concept and scope of the claimed protection is not departed from, may be used also under the enlightenment of the present invention
By make it is many in the form of, such as：
(1) the locating dowel in embodiment 1 is exchanged with the set location of elastic self-fastening button, it is fixed to be set on stage carrier
Position post, elastic self-fastening button is set on objective table, can also play same effect.
(2) light-emitting diode optical arrays are set in the both sides of linear amasthenic lens, so, can make it that light is more uniform.
These are belonged within protection scope of the present invention.
Claims (8)
- A kind of 1. color collecting device of reagent strip, it is characterised in that：Including be installed in main body display device, contact figure As sensor, control circuit and stage carrier, wherein,The contact-type image sensor includes sensor support body, and sensor circuit is provided with the top of the sensor support body Plate, the lower surface of the sensor circuit board are provided with photodiode array, and the lower surface of the photodiode array is set Filter coating is equipped with, line focus camera lens is provided with below the filter coating, at least one side of the line focus camera lens Light emitting diode matrix is provided with, the photodiode array, the light emitting diode matrix, the line focus camera lens are equal On sensor support body, the lower surface of the sensor support body is provided with for protecting the photodiode array, institute The cover plate of line focus camera lens and the light emitting diode matrix is stated, plane where the light emitting diode matrix and protection Glass planar is in predetermined angle；The stage carrier is located at the lower section of contact-type image sensor, and it has objective table sliding groove, and the objective table is slided Dynamic groove is provided with stage guide, and the objective table is slidably mounted in the objective table sliding groove, and the objective table, which is provided with, to be used In the article putting groove for accommodating horizontal positioned reagent strip, and the depth of the article putting groove is more than the thickness of reagent strip, described to cause The upper surface of reagent strip is located at below the cover plate and does not contact the cover plate；The light that the light emitting diode matrix is sent is irradiated to the upper surface of the reagent strip through the cover plate, occurs anti- The cover plate is again passed through after penetrating, and after the focusing of the line focus camera lens and the optical filtering of the filter coating, is thrown The photodiode array is mapped to, the photodiode array converts optical signals to electric signal and is delivered to the sensing Device circuit board, the sensor circuit board transfer signals to the control circuit, and the control circuit carries out colorimetric, and will survey Amount result is shown in the display device.
- 2. the color collecting device of reagent strip according to claim 1, it is characterised in that：The bottom of the main body is provided with extremely Few two are used to place and position the support supporting plate of the stage carrier, the upper surface of each support supporting plate with The lower surface of the cover plate is parallel and equidistant with the cover plate lower surface.
- 3. the color collecting device of reagent strip according to claim 1 or 2, it is characterised in that：The display device is tactile Screen is touched, the touch-screen electrically connects with the control circuit, and the touch-screen is used to select detection project for user and is detected The species of reagent strip simultaneously shows measurement result.
- 4. the color collecting device of reagent strip according to claim 1 or 2, it is characterised in that：Control circuit will be measured and tied Fruit is converted to bar code or Quick Response Code, and shows on the display apparatus.
- 5. the color collecting device of reagent strip according to claim 1 or 2, it is characterised in that：The objective table gos deep into One end of the stage carrier is provided with locating dowel, and the locating dowel is used to be put into color collecting device in the objective table It is engaged when middle with the elastic self-fastening button being arranged on the stage carrier to realize the positioning of the objective table.
- 6. the color collecting device of reagent strip according to claim 1 or 2, it is characterised in that：The objective table gos deep into One end of the stage carrier sets flexible self-fastening button, is set on stage carrier on position corresponding with the elastic self-fastening button Locating dowel is equipped with, the locating dowel is used for when the objective table is put into color collecting device with being arranged at the objective table Elastic self-fastening button be engaged to realize the positioning of the objective table.
- 7. the color collecting device of reagent strip according to claim 1, it is characterised in that：The light emitting diode matrix institute Plane is into 30 ° of angles where plane and the cover plate.
- 8. the color collecting device of reagent strip according to claim 1, it is characterised in that：The bottom of the article putting groove and institute The distance for stating cover plate lower surface is bigger 1-1.5mm than the thickness at the color lump position of the reagent strip.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610169758.7A CN105698934B (en) | 2016-03-23 | 2016-03-23 | The color collecting device of reagent strip |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610169758.7A CN105698934B (en) | 2016-03-23 | 2016-03-23 | The color collecting device of reagent strip |
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| CN105698934A CN105698934A (en) | 2016-06-22 |
| CN105698934B true CN105698934B (en) | 2017-11-21 |
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| CN201610169758.7A Expired - Fee Related CN105698934B (en) | 2016-03-23 | 2016-03-23 | The color collecting device of reagent strip |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107037208B (en) * | 2016-11-18 | 2019-03-29 | 百奥森（江苏）食品安全科技有限公司 | A kind of Multifunctional fluorescent immunochromatographirapid rapid quantitative detection card |
| CN109001191A (en) * | 2018-06-06 | 2018-12-14 | 西安纸贵互联网科技有限公司 | A kind of sxemiquantitative recognition methods of external diagnosis reagent and device |
| CN110044883A (en) * | 2019-04-07 | 2019-07-23 | 东莞市金翔光电科技有限公司 | Immune quantitative analysis system color developing detection method |
| CN110044882A (en) * | 2019-04-07 | 2019-07-23 | 东莞市金翔光电科技有限公司 | Immune quantitative analysis system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7573575B2 (en) * | 2005-12-29 | 2009-08-11 | Honeywell International Inc. | System and method for color measurements or other spectral measurements of a material |
| JP4710680B2 (en) * | 2006-03-23 | 2011-06-29 | トヨタ自動車株式会社 | Object colorimetry |
| CN201707304U (en) * | 2010-06-08 | 2011-01-12 | 惠州市德赛西威汽车电子有限公司 | Device for automated optical inspection of surface of product |
| CN102798637B (en) * | 2012-08-29 | 2014-12-03 | 北京大恒图像视觉有限公司 | Device and method for detecting surface quality of printed matters |
| CN205426341U (en) * | 2016-03-23 | 2016-08-03 | 微堪健康科技（上海）有限公司 | Reagent strips's colour collection system |
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