CN105683158A - 4-甲基磺酰基-2-丁烯腈及其药学用途 - Google Patents

4-甲基磺酰基-2-丁烯腈及其药学用途 Download PDF

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Publication number
CN105683158A
CN105683158A CN201480055104.0A CN201480055104A CN105683158A CN 105683158 A CN105683158 A CN 105683158A CN 201480055104 A CN201480055104 A CN 201480055104A CN 105683158 A CN105683158 A CN 105683158A
Authority
CN
China
Prior art keywords
pain
inflammation
pharmaceutically acceptable
butenenitrile
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480055104.0A
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English (en)
Chinese (zh)
Inventor
约瑟夫·P·圣劳伦特
杰拉尔德·S·琼斯
大卫·M·布雷斯
斯考特·A·古德里奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olatec Therapeutics Inc
Original Assignee
Olatec Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olatec Therapeutics Inc filed Critical Olatec Therapeutics Inc
Publication of CN105683158A publication Critical patent/CN105683158A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201480055104.0A 2013-10-07 2014-10-01 4-甲基磺酰基-2-丁烯腈及其药学用途 Pending CN105683158A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361887776P 2013-10-07 2013-10-07
US61/887,776 2013-10-07
PCT/US2014/058685 WO2015054008A1 (en) 2013-10-07 2014-10-01 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use

Publications (1)

Publication Number Publication Date
CN105683158A true CN105683158A (zh) 2016-06-15

Family

ID=52813515

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480055104.0A Pending CN105683158A (zh) 2013-10-07 2014-10-01 4-甲基磺酰基-2-丁烯腈及其药学用途

Country Status (4)

Country Link
EP (1) EP3055286A4 (https=)
JP (1) JP6426746B2 (https=)
CN (1) CN105683158A (https=)
WO (1) WO2015054008A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015094626A1 (en) * 2013-12-20 2015-06-25 The Procter & Gamble Company Diaper with improved cuffs and comfort

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444175A (en) * 1966-11-09 1969-05-13 Merck & Co Inc Certain picolylmethyl sulfones
CN103260613A (zh) * 2010-12-15 2013-08-21 欧拉泰克工业有限责任公司 用于治疗炎症和疼痛的3-甲磺酰基丙腈
WO2014043144A1 (en) * 2012-09-11 2014-03-20 Olatec Industries Llc Methods for treating inflammation and pain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6151723B2 (ja) * 2012-02-27 2017-06-21 オラテック セラピューティクス リミティド ライアビリティ カンパニー ３−メチルスルホニルプロピオニトリルを調製するプロセス

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444175A (en) * 1966-11-09 1969-05-13 Merck & Co Inc Certain picolylmethyl sulfones
CN103260613A (zh) * 2010-12-15 2013-08-21 欧拉泰克工业有限责任公司 用于治疗炎症和疼痛的3-甲磺酰基丙腈
WO2014043144A1 (en) * 2012-09-11 2014-03-20 Olatec Industries Llc Methods for treating inflammation and pain

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KHAMIS, G. G.等: "Synthesis of γ-functionalised allyl sulphones", 《OXIDATION COMMUNICATIONS》 *
YANG, ZHEN YU等: "Preparation of α,α-difluoromethylene functionalized sulfones", 《HETEROATOM CHEMISTRY》 *

Also Published As

Publication number Publication date
JP2016539179A (ja) 2016-12-15
EP3055286A4 (en) 2017-05-24
EP3055286A1 (en) 2016-08-17
JP6426746B2 (ja) 2018-11-21
WO2015054008A1 (en) 2015-04-16

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160615