CN105663826A

CN105663826A - Traditional Chinese medicine composition for treating gout

Info

Publication number: CN105663826A
Application number: CN201610090832.6A
Authority: CN
Inventors: 姜丽莎
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-19
Filing date: 2016-02-19
Publication date: 2016-06-15

Abstract

The invention relates to a traditional Chinese medicine composition for treating gout. The traditional Chinese medicine composition is prepared from, by weight, 10-30 parts of spreading hedyotis herb, 5-25 parts of fish poison yam, 5-20 parts of Indian iphigenia bulbs, 5-25 parts of scandent schefflera stems and leaves, 5-25 parts of herba siegesbeckiae, 5-20 parts of pine nodular branches, 5-25 parts of radix Morindae officinalis, 5-20 parts of geckos, 5-25 parts of radix aconite, 5-25 parts of obscured homalomena rhizomes, 5-20 parts of sappan wood, 5-25 parts of glabrous greenbrier rhizomes, 5-20 parts of orientvine stems, 5-25 parts of cortex acanthopanacis, 10-30 parts of common cruculigo rhizomes, 5-25 parts of root bark of ampelopsis humulifolia bunge, 5-20 parts of snow of June herb, 5-20 parts of sargentg loryvine stems, 5-25 parts of himalayan teasel roots, 5-20 parts of roots of stephania tetrandra, 5-25 parts of rhizoma atractylodis, 5-25 parts of rhizoma imperatae, 5-25 parts of radix gentianae macrophyllae and 5-15 parts of licorice roots. The traditional Chinese medicine composition has the effects of nourishing the liver and the kidneys, clearing away heat and toxic materials, promoting diuresis to eliminate turbidity, clearing and activating the channels and collaterals, inducing diuresis to alleviate edema, and promoting blood circulation to arrest pain, and is remarkable in treatment effect and reliable in effect when used for treating gout.

Description

A kind of Chinese medicine composition treating gout

Technical field

The present invention relates to the pharmaceutical product not determining structure of a kind of traditional herbal medicines, especially a kind of Chinese medicine composition treating gout.

Background technology

Gout is one group of different substantiality disease that blood uric acid caused by purine metabolic disturbance and (or) uric acid excretion disorder increases, taking toe, the joint congestion and swelling pain such as refer to or the heat that occurs together etc. as main clinical manifestation. Its clinical characters is: hyperuricemia, gouty acute arthritis recurrent exerbation, tophaceous deposition, characteristic chronic arthritis and joint deformity, often involves kidney and causes chronic interstitial nephritis and kidney urate calculus to be formed. Patient is mostly the male sex of more than 40 years old, and women is more common in climacterium sequela. Along with the raising of living standards of the people, the incidence of gout caused by hyperuricemia increases day by day. At present, whole world goat patient is up to 1.2 hundred million, and China goat patient is more than 4,000 ten thousand people, and sickness rate is higher than world average level. Gout and complication thereof can reduce the quality of life of people, seriously endanger health of people. Colchicine is the medicine of current clinical conventional treatment gout, but it exists severe side effect, such as Nausea and vomiting, watery diarrhea, hepatocellular injury, bone marrow depression, alopecia and renal failure etc., makes clinical application be subject to a definite limitation.

The traditional Chinese medical science is thought, gout is mainly due to the ferritic deficiency of Yin, eating and drinking without temperance, obesity, disorder of emotion, the diseases caused by external factors six external factors which cause diseases, wet turbid stasis blocking, joint channels and collaterals of being detained, and gas blood is smooth, caused by the evil infringement of poison.

According to theory of traditional Chinese medical science, for the pathogeny of gout, adopt nourishing liver and kidney, clearing heat and detoxicating, sharp wetting to go therapy turbid, clearing and activating the channels and collaterals, inducing diuresis to remove edema, promoting blood circulation and stopping pain, carry out dialectical prescription compatibility, to reach the object treated both principal and secondary aspect of disease.

Summary of the invention

Treating, in order to overcome, the deficiency that gout exists side effect in prior art, the present invention provides a kind of and prepares the Chinese medicine composition for the treatment of gout that simplicity, cost are low, evident in efficacy, have no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating gout, it is characterized in that: its Chinese medicine material and weight be: Spreading Hedyotis Herb 10-30 part, Bi 5-25 part, Pseudobulbus Cremastrae Seu Pleiones 5-20 part, Schefflera arboricola Hagata 5-25 part, Xian grass 5-25 part, turpentine 5-20 part, Root of Medicinal Indian mulberry 5-25 part, gecko 5-20 part, monkshood 5-25 part, Rhizome of Obscured Homalomena 5-25 part, bush 5-20 part, Rhizome of Glabrous Greenbrier 5-25 part, Stem of Orientoine 5-20 part, Wu Chia Pee 5-25 part, thizoma curculiginis 10-30 part, seven jiaos of radix ampelopsis 5-25 parts, Serissa japonica 5-20 part, Sargent gloryvine 5-20 part, teasel root 5-25 part, root of fangji 5-20 part, rhizoma atractylodis 5-25 part, Rhizome of Lalang Grass 5-25 part, bark of ash 5-25 part, Radix Glycyrrhizae 5-15 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating gout, it is characterized in that: its Chinese medicine material and weight be: Spreading Hedyotis Herb 20 parts, Bi 15 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Schefflera arboricola Hagata 15 parts, Xian grass 15 parts, turpentine 10 parts, Root of Medicinal Indian mulberry 15 parts, gecko 10 parts, monkshood 15 parts, Rhizome of Obscured Homalomena 15 parts, bush 10 parts, Rhizome of Glabrous Greenbrier 15 parts, Stem of Orientoine 10 parts, Wu Chia Pee 15 parts, thizoma curculiginis 20 parts, seven jiaos of radix ampelopsis 15 parts, Serissa japonica 10 parts, Sargent gloryvine 10 parts, teasel root 15 parts, the root of fangji 10 parts, rhizoma atractylodis 15 parts, Rhizome of Lalang Grass 15 parts, bark of ash 15 parts, 10 parts, Radix Glycyrrhizae.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription. In Chinese medicine composition of the present invention: Spreading Hedyotis Herb has effect clearing heat and detoxicating, inducing diuresis to remove edema, promoting blood circulation and stopping pain; The profit that has Bi wets and goes turbid, to dispel wind and relieving paralysis effect; Pseudobulbus Cremastrae Seu Pleiones has effect clearing heat and detoxicating, dissipating phlegm and resolving masses; Schefflera arboricola Hagata has effect of wind-expelling pain-stopping, activating blood circulation and reducing swelling; Xian grass have dispel rheumatism, clearing and activating the channels and collaterals, clearing heat and detoxicating effect; Turpentine has eliminating dampness of dispeling the wind、Channels sootheing and network vessel quickening、Effect of promoting blood circulation and stopping pain; Root of Medicinal Indian mulberry has effect that kidney tonifying is supporing yang, strengthens muscles and bones, dispel rheumatism; Gecko has and drives that wind is relieving convulsion, effect of detoxicating and resolving a mass; Monkshood have dispel rheumatism, effect of antalgic; Rhizome of Obscured Homalomena has wind-damp dispelling, stimulates the circulation of the blood and cause the muscles and joints to relax, effect of alleviating pain and detumescence; Bush has effect of promoting blood circulation to remove blood stasis, subduing swelling and relieving pain; Rhizome of Glabrous Greenbrier has the effect in clearing heat and detoxicating, clearing damp Li Shui, strengthening the spleen and stomach, profit joint; Stem of Orientoine has effect of wind-damp dispelling, the meridian dredging, diuresis; Wu Chia Pee has effect of wind-damp dispelling, invigorating the liver and kidney, strengthening the bones and muscles; Thizoma curculiginis has that kidney tonifying is supporing yang, benefiting essence-blood, strengthening the bones and muscles, promoting circulation of blood detumescence effect; Seven jiaos of radix ampelopsis have promoting blood circulation to remove blood stasis, eliminating inflammation and expelling toxin, myogenic long bone, effect except wind clearing damp; Serissa japonica has expelling wind to resolve the exterior、Clearing heat and promoting diuresis、The effect stimulated the circulation of the blood and cause the muscles and joints to relax; Sargent gloryvine has clearing heat and detoxicating, promoting blood circulation and removing obstruction in channels, to relieve internal heat the loose stasis of blood, wind dispelling insecticide effect; Teasel root has effect of invigorating the liver and kidney, strengthening the bones and muscles, tune blood vessels; The root of fangji has effect of inducing diuresis to remove edema, wind-expelling pain-stopping; Rhizoma atractylodis have effect drying damp and strengthening spleen, expelling wind and cold; Rhizome of Lalang Grass has effect of cooling blood for hemostasis, clearing away heat and promoting diuresis; Bark of ash has effect of rheumatism, relaxing muscles and tendons network, clearind deficient heat; Radix Glycyrrhizae have invigorate the spleen and benefit qi, effect of clearing heat and detoxicating, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription. The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, play altogether nourishing liver and kidney, clearing heat and detoxicating, profit is wet goes effect turbid, clearing and activating the channels and collaterals, inducing diuresis to remove edema, promoting blood circulation and stopping pain, the treatment of gout is reached and treats both principal and secondary aspect of disease.

The component of the present composition all adopts natural Chinese medicine material, and its preparation is easy, medicine source is wide, cost is low. The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts water decoction to use. Through clinical application checking, it is reliably evident in efficacy, mild in medicine property and, toxic side effect does not occur, has efficiency to reach 92%, curative ratio 65%.

Embodiment

Below in conjunction with embodiment, the invention will be further described.

Embodiment 1

Treating a Chinese medicine composition for gout, its Chinese medicine material and weight proportion be: Spreading Hedyotis Herb 20g, Bi 15g, Pseudobulbus Cremastrae Seu Pleiones 10g, Schefflera arboricola Hagata 15g, Xian grass 15g, turpentine 10g, Root of Medicinal Indian mulberry 15g, gecko 10g, monkshood 15g, Rhizome of Obscured Homalomena 15g, bush 10g, Rhizome of Glabrous Greenbrier 15g, Stem of Orientoine 10g, Wu Chia Pee 15g, thizoma curculiginis 20g, seven jiaos of radix ampelopsis 15g, Serissa japonica 10g, Sargent gloryvine 10g, teasel root 15g, root of fangji 10g, rhizoma atractylodis 15g, Rhizome of Lalang Grass 15g, bark of ash 15g, Radix Glycyrrhizae 10g.

Embodiment 2

Treating a Chinese medicine composition for gout, its Chinese medicine material and weight proportion be: Spreading Hedyotis Herb 15g, Bi 25g, Pseudobulbus Cremastrae Seu Pleiones 12g, Schefflera arboricola Hagata 20g, Xian grass 5g, turpentine 15g, Root of Medicinal Indian mulberry 10g, gecko 20g, monkshood 5g, Rhizome of Obscured Homalomena 25g, bush 12g, Rhizome of Glabrous Greenbrier 20g, Stem of Orientoine 5g, Wu Chia Pee 25g, thizoma curculiginis 10g, seven jiaos of radix ampelopsis 20g, Serissa japonica 5g, Sargent gloryvine 15g, teasel root 10g, root of fangji 20g, rhizoma atractylodis 5g, Rhizome of Lalang Grass 25g, bark of ash 10g, Radix Glycyrrhizae 8g.

Embodiment 3

Treating a Chinese medicine composition for gout, its Chinese medicine material and weight proportion be: Spreading Hedyotis Herb 25g, Bi 10g, Pseudobulbus Cremastrae Seu Pleiones 15g, Schefflera arboricola Hagata 5g, Xian grass 20g, turpentine 12g, Root of Medicinal Indian mulberry 25g, gecko 5g, monkshood 20g, Rhizome of Obscured Homalomena 10g, bush 15g, Rhizome of Glabrous Greenbrier 5g, Stem of Orientoine 20g, Wu Chia Pee 10g, thizoma curculiginis 25g, seven jiaos of radix ampelopsis 5g, Serissa japonica 20g, Sargent gloryvine 12g, teasel root 25g, root of fangji 5g, rhizoma atractylodis 20g, Rhizome of Lalang Grass 10g, bark of ash 25g, Radix Glycyrrhizae 5g.

Embodiment 4

Treating a Chinese medicine composition for gout, its Chinese medicine material and weight proportion be: Spreading Hedyotis Herb 10g, Bi 20g, Pseudobulbus Cremastrae Seu Pleiones 5g, Schefflera arboricola Hagata 25g, Xian grass 10g, turpentine 20g, Root of Medicinal Indian mulberry 5g, gecko 15g, monkshood 10g, Rhizome of Obscured Homalomena 20g, bush 5g, Rhizome of Glabrous Greenbrier 25g, Stem of Orientoine 12g, Wu Chia Pee 20g, thizoma curculiginis 15g, seven jiaos of radix ampelopsis 25g, Serissa japonica 12g, Sargent gloryvine 20g, teasel root 5g, root of fangji 15g, rhizoma atractylodis 10g, Rhizome of Lalang Grass 20g, bark of ash 5g, Radix Glycyrrhizae 15g.

Embodiment 5

Treating a Chinese medicine composition for gout, its Chinese medicine material and weight proportion be: Spreading Hedyotis Herb 30g, Bi 5g, Pseudobulbus Cremastrae Seu Pleiones 20g, Schefflera arboricola Hagata 10g, Xian grass 25g, turpentine 5g, Root of Medicinal Indian mulberry 20g, gecko 12g, monkshood 25g, Rhizome of Obscured Homalomena 5g, bush 20g, Rhizome of Glabrous Greenbrier 10g, Stem of Orientoine 15g, Wu Chia Pee 5g, thizoma curculiginis 30g, seven jiaos of radix ampelopsis 10g, Serissa japonica 15g, Sargent gloryvine 5g, teasel root 20g, root of fangji 2g, rhizoma atractylodis 25g, Rhizome of Lalang Grass 5g, bark of ash 20g, Radix Glycyrrhizae 12g.

Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament. Concrete grammar is as follows: the Chinese medicine material of prescription is put into container, adds cold water and covers powder, soaks 15～20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time and decocts and boil, adopts intense fire to decoct and boil, with slow fire boiling 20～30 minutes after boiling before not boiling; Second time is decocted and is boiled, and adds water and did not have powder about 4 centimetres, and water is decocted after boiling and boiled 15～20 minutes. Decoct to boil for twice and get juice, merge.

The present invention, with a kind of Chinese medicine composition treating gout given by embodiment 1, does clinical efficacy and is summarized as follows:

One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 79 example, female 21 example, 40～65 years old age.

Two, diagnosis basis: the Case definition with reference to gout in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ":

1, mainly with single toe articulations digitorum manus, soldier's so congestion and swelling pain, pain is acute gradually stings such as tiger, light night in daytime very, recurrent exerbation. Can occur together the diseases such as heat, headache;

2, it is more common in aging male, can have gout family history. Often because of fatigue, eating and drinking immoderately, eat high purine food, drink and catching cold etc. is brought out;

3, from the beginning of falling ill by simple joint, taking Metatarsophalangeal joint as common. Continue then ankle, with, finger and other Minor articulus, red and swollen heat pain occurs, very then joint cavity can sepage. After recurrent exerbation, can with periarticular and auricle, helix and toe, refer between bone occur " block scrofula " (uratoma);

4, blood uric acid, acid of urinating are increased.Stage of attack, total white blood cells can increase;

5, doing the detection of kidney B ultrasonic if desired, routine urinalysis, renal function etc. check, to understand nephropathy situation after gout. Sheet inspection taken the photograph by X line: can show that the sclerotin of cartilage edge adjacent joints has irregular sample round defect of giving a farfetched interpretation.

Three, usage and dosage: during clinical application, one day one dose, water is decocted and is got juice for twice and be about 400ml, and point early, evening warmly takes for twice on an empty stomach. It within ten days, it is a course for the treatment of. Avoid cold and uncooked food during treatment the thing of pungent stimulation.

Four, criterion of therapeutical effect: the efficacy assessment standard with reference to gout in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ":

(1) fully recover: symptom disappears, and laboratory examination is normal;

(2) effective: arthroncus is cut down, pain relief, and laboratory examination is improved;

(3) invalid: symptom and laboratory examination are unchanged.

Five, result for the treatment of: in this clinical observation case, take medicine 2-5 the course for the treatment of, recovery from illness 65 example, follows up a case by regular visits to and has no recurrence; Effective 27 examples, invalid 8 examples. Toxic side effect is there is not during treatment.

Six, model case:

Case 1:

Poplar, man, 45 years old. Patient Yin Chang eats high purine food, drinks, and finger, toes, instep repeatability swelled and ache more than 1 year. Whenever tired or after having a cold, its finger, toes have secret anguish and gradually aggravate, and with night more so, even be difficult to fall asleep, locally scorching hot redness. Once colchicine treatment was taken, but poor effect. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, swelling and ache of toes alleviates; Continuing to take 3 courses for the treatment of, all symptoms disappear, and cure.

Case 2:

Woods, female, 52 years old. Suffer from nearly 2 years of gout, lower limb Minor articulus red and swollen heat pain, refuse by, the local touched is scorching hot, occurs together hot thirsty, vexed uneasiness, Huang of urinating. Examine and see: tongue is red, yellow and greasy fur, slippery and rapid pulse. It is diagnosed as: gout. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the symptoms such as pain alleviate, and continue to take 2 courses for the treatment of, and all symptoms disappear, and cure. Follow up a case by regular visits to half a year without recurrence.

Case 3:

Certain, male recklessly, 63 years old. The violent pain of trick redness and swelling of joints, in more than 1 year of recurrent exerbation, eats seafood every time and has the beer postemphasis. Examine as gout through checking. Through treating with Western medicine antigout, effect is not obvious. Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, arthroncus is cut down, pain relief; Continuing to take 2 courses for the treatment of, symptom disappears, and cures.

Claims

1. treat the Chinese medicine composition of gout for one kind, it is characterized in that: its Chinese medicine material and weight be: Spreading Hedyotis Herb 10-30 part, Bi 5-25 part, Pseudobulbus Cremastrae Seu Pleiones 5-20 part, Schefflera arboricola Hagata 5-25 part, Xian grass 5-25 part, turpentine 5-20 part, Root of Medicinal Indian mulberry 5-25 part, gecko 5-20 part, monkshood 5-25 part, Rhizome of Obscured Homalomena 5-25 part, bush 5-20 part, Rhizome of Glabrous Greenbrier 5-25 part, Stem of Orientoine 5-20 part, Wu Chia Pee 5-25 part, thizoma curculiginis 10-30 part, seven jiaos of radix ampelopsis 5-25 parts, Serissa japonica 5-20 part, Sargent gloryvine 5-20 part, teasel root 5-25 part, root of fangji 5-20 part, rhizoma atractylodis 5-25 part, Rhizome of Lalang Grass 5-25 part, bark of ash 5-25 part, Radix Glycyrrhizae 5-15 part.

2. a kind of Chinese medicine composition treating gout according to claim 1, it is characterized in that: its Chinese medicine material and weight be: Spreading Hedyotis Herb 20 parts, Bi 15 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts, Schefflera arboricola Hagata 15 parts, Xian grass 15 parts, turpentine 10 parts, Root of Medicinal Indian mulberry 15 parts, gecko 10 parts, monkshood 15 parts, Rhizome of Obscured Homalomena 15 parts, bush 10 parts, Rhizome of Glabrous Greenbrier 15 parts, Stem of Orientoine 10 parts, Wu Chia Pee 15 parts, thizoma curculiginis 20 parts, seven jiaos of radix ampelopsis 15 parts, Serissa japonica 10 parts, Sargent gloryvine 10 parts, teasel root 15 parts, the root of fangji 10 parts, rhizoma atractylodis 15 parts, Rhizome of Lalang Grass 15 parts, bark of ash 15 parts, 10 parts, Radix Glycyrrhizae.