CN105663677A - Traditional Chinese medicine composition for treating radiation gastritis - Google Patents
Traditional Chinese medicine composition for treating radiation gastritis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating radiation gastritis. The traditional Chinese medicine composition is prepared from radix prismatomeris connatae, lambert raspberry root or leave, Japanese stephania root, jambolan fruit, wintersweet immature flower, fiveleaf akebia fruit, dwarf mallow root, whorledleaf solomonseal rhizome, bitter citrus immature flower and sea cucumber intestine. An effective method for treating radiation gastritis is provided, the occurrence time of radiation gastritis can be delayed, and the treatment suspending or withdrawing case number is reduced.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly to the Chinese medicine composition of a kind of therapeutic radiation gastritis.
Background technology
Radiation gastritis is the severe complication caused after epigastrium accepts radiotherapy. Owing to radiation gastritis sickness rate is relatively low, often ignored by people, but one of reason causing gastrointestinal hemorrhage. Attention is concentrated mainly on lonizing radiation in the damage of intestinal by conventional people, and along with carrying out of change of disease spectrum and radiation cure, being gradually increased of radiation gastritis sickness rate, the focus that people pay close attention to also has transferred to stomach from original intestinal injury. Radiation gastritis clinical manifestation is pain under xiphoid-process, dysphagia, dyspepsia, heartburn sense and melena etc., severe patient melena repeatedly, has blood in stool. Radiation gastritis clinical symptoms reduces the quality of life of patient, even threatens the life of patient. The curative effect of Modern medical therapy primary disease is unsatisfactory, not yet sets up effective therapeutic scheme of therapeutic radiation gastritis and bleeding thereof. Therefore find the effective treatment means for radiation gastritis clinically and seem particularly urgent. The present inventor, through clinical trial repeatedly, develops the Chinese medicine composition of a kind of therapeutic radiation gastritis, satisfactory effect.
Summary of the invention
It is an object of the invention to overcome in prior art and do not put forward for the deficiency of the rational Chinese medicine composition of radiation gastritis compatibility, namely a kind of therapeutic radiation gastritis Chinese medicine composition is provided.
In order to realize foregoing invention purpose, the invention provides techniques below scheme:
The Chinese medicine composition of a kind of therapeutic radiation gastritis, is made up of the crude drug of following mass ratio:
Xanthorrhiza 10～30 parts, Rubus lambertianus 10～30 parts, Radix Stephaniae Japonicae 9～15 parts, sheep dung fruit 8～12 parts, Flos Chimonanthi Praecocis 3～5 parts, Fructus Akebiae 9～15 parts, dawrf mallow root 15～25 parts, Rhizoma Polygonati Verticillati 6～10 parts, Citrus aurantium L. var. amara Engl. 1～3 part, 8～12 parts of Stichopus japonicus internal organs.
Xanthorrhiza: micro-hardship, cool. Cooling blood for hemostasis, dampness removing jaundice eliminating, the strong muscle of dissipating blood stasis. Cure mainly bleeding from the gum, anemia, hepatitis, rheumatic arthritis, urinary tract infection, traumatic injury.
Rubus lambertianus: bitter, puckery, flat. Expelling wind and clearing away heat, cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling. Cure mainly anemopyretic cold, rheumatic arthralgia, hemiplegia, hemoptysis, epistaxis, have blood in stool, metrorrhagia, amenorrhea, dysmenorrhea, puerperal abdonimal pain, skin infection.
Radix Stephaniae Japonicae: bitter, acrid, cold. Heat-clearing and toxic substances removing, wind-expelling pain-stopping, inducing diuresis to remove edema. Cure mainly laryngopharynx swelling and pain, carbuncle furuncle, venom, rheumatic arthralgia, stomachache, beriberi edema.
Sheep dung fruit: sweet, sour, flat. Astringe the lung and relieving asthma, promote the production of body fluid, astringing intestine to stop diarrhea. Curing mainly phthisical cough, dyspnea due to deficiency, Tianjin wound is thirsty, chronic diarrhea chronic dysentery.
Flos Chimonanthi Praecocis: hardship pungent, sweet, micro-, cool, mild toxicity, attaches to the lung and stomach meridians. Expelling summer-heat heat clearing away, regulating the flow of QI to alleviate depression. Cure mainly summer-heat excessive thirst, dizzy, gastral cavity painful abdominal mass uncomfortable in chest, globus hystericus, laryngopharynx swelling and pain, pertussis, infantile measles, scald.
Fructus Akebiae: micro-hardship, flat, returns liver, stomach, bladder warp. Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis. Curing mainly stagnation of liver-QI and stomach-QI, gastral cavity abdomen, distending pain over the hypochondrium, diet does not disappear, dysentery, hernia, lumbago, menoxenia, dysmenorrhea, goiter, scrofula, malignant tumor.
Dawrf mallow root: sweet, warm. QI invigorating hidroschesis, diuretic lactogenesis, expelling pus and toxin by strengthening QI. Curing mainly fatigue and weakness, visceroptosis, cough due to deficiency of the lung, spontaneous sweating, edema, hypogalactia, metrorrhagia, carbuncle difficulty is burst, or bursts and do not close up.
Rhizoma Polygonati Verticillati: hardship sweet, micro-, cool. Spleen reinforcing lung moistening, suppressing the hyperactive liver, removing toxicity for eliminating carbuncles. Cure mainly weakness of the spleen and stomach, xeropulmonary cough, dizziness, headache, sore, carbuncle and painful swelling.
Citrus aurantium L. var. amara Engl.: hardship pungent, sweet, micro-, flat. Regulate the flow of vital energy the chest stuffiness relieving, stomach function regulating preventing or arresting vomiting. Cure mainly painful abdominal mass in the heart vexed, abdominal distention, anorexia, nausea and vomiting.
Stichopus japonicus internal organs: relieving convulsion, stomach function regulating, rash of detoxifying, promoting regeneration of the tissue and arresting bleeding. Cure mainly epilepsy, infantile dyspepsia, gastric and duodenal ulcers, measles, furuncle, wound.
Radiation gastritis belongs to the categories such as the traditional Chinese medical science " stomachache " " hypochondriac pain " " acid regurgitation " " noisy ". The traditional Chinese medical science thinks that lonizing radiation belong to the heresy of pyretic toxicity, and easily consumption impairment of QI is cloudy. Accepting the patient of radiotherapy because MPMN, this is the people of body void, and again by radiation injury (heresy of pyretic toxicity), therefore primary disease belongs to the card of deficiency in origin and excess in superficiality, simulataneous insufficiency and excessive. The present invention adopts xanthorrhiza, Rubus lambertianus, Radix Stephaniae Japonicae expelling wind and clearing away heat, removing heat from blood and promoting blood circulation; Sheep dung fruit is promoted the production of body fluid, astringing intestine to stop diarrhea; Flos Chimonanthi Praecocis, Fructus Akebiae dispersing the stagnated liver-QI for regulating the stomach; Dawrf mallow root replenishing QI to invigorate the spleen; Rhizoma Polygonati Verticillati spleen reinforcing lung moistening; Citrus aurantium L. var. amara Engl. stomach function regulating preventing or arresting vomiting; Stichopus japonicus internal organs stomach function regulating, removing toxic substances, promoting regeneration of the tissue and arresting bleeding. All medicines share, and play clearing away heat and cooling blood, supplementing QI and nourishing YIN, the effect of invigorating the spleen and regulating the stomach altogether.
Preferably, the Chinese medicine composition of described therapeutic radiation gastritis is made up of the crude drug of following mass ratio:
Xanthorrhiza 15～25 parts, Rubus lambertianus 15～25 parts, Radix Stephaniae Japonicae 11～13 parts, sheep dung fruit 9～11 parts, Flos Chimonanthi Praecocis 3～5 parts, Fructus Akebiae 11～13 parts, dawrf mallow root 18～22 parts, Rhizoma Polygonati Verticillati 7～9 parts, Citrus aurantium L. var. amara Engl. 1～3 part, 9～11 parts of Stichopus japonicus internal organs.
It is further preferred that the Chinese medicine composition of described therapeutic radiation gastritis is made up of the crude drug of following mass ratio:
Xanthorrhiza 20 parts, Rubus lambertianus 20 parts, Radix Stephaniae Japonicae 12 parts, sheep dung fruit 10 parts, Flos Chimonanthi Praecocis 4 parts, Fructus Akebiae 12 parts, dawrf mallow root 20 parts, Rhizoma Polygonati Verticillati 8 parts, Citrus aurantium L. var. amara Engl. 2 parts, 10 parts of Stichopus japonicus internal organs.
The Chinese medicine composition of described therapeutic radiation gastritis can adopt existing Chinese medicine preparation technology to prepare into any conventional oral preparations, such as decocting can be adopted to obtain water decoction said components, it is also possible to by other existing Chinese medicine preparation technology, the Chinese medicine composition of described therapeutic radiation gastritis to be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
Compared with prior art, beneficial effects of the present invention
The Chinese medicine composition of therapeutic radiation gastritis provided by the invention, it is provided that the effective ways of a kind of therapeutic radiation gastritis, can postpone the time of occurrence of radiation gastritis, reduces the case load suspending or abandoning radiotherapy.
The Chinese medicine composition of a kind of therapeutic radiation gastritis, clinical efficacy is summed up
1 physical data
Select the hepatocarcinoma of row gamma knife treatment, cancer of pancreas, metastasis of retroperitoneal lymph node patient 60 example, be randomly divided into treatment group and matched group, often organize each 30 examples.Male 18 examples for the treatment of group, female 12 example; Year mean age (63.60 ± 9.77); KPS scoring (82.36 ± 5.14) point; Hepatocarcinoma 19 example, cancer of pancreas 5 example, metastasis of retroperitoneal lymph node 6 example. Matched group man's 20 examples, female 10 example; Year mean age (62.52 ± 8.78); KPS scoring (83.48 ± 6.21) point; Hepatocarcinoma 21 example, cancer of pancreas 4 example, metastasis of retroperitoneal lymph node 5 example. Before two groups of ages, sex, sick kind, treatments, KPS scoring is compared, and no significant difference (P > 0.05) has comparability.
2 Therapeutic Method
Matched group starts to give metoclopramide 10mg from gamma knife treatment on the 1st day, oral, day 3 times; Montmorillonite powder 3g, takes after mixing it with water, day 3 times. Treatment group is the Chinese medicine composition water decoction of oral therapeutic radiation gastritis provided by the invention on matched group basis, composed as follows:
Xanthorrhiza 20 grams, Rubus lambertianus 20 grams, Radix Stephaniae Japonicae 12 grams, sheep dung fruit 10 grams, Flos Chimonanthi Praecocis 4 grams, Fructus Akebiae 12 grams, dawrf mallow root 20 grams, Rhizoma Polygonati Verticillati 8 grams, Citrus aurantium L. var. amara Engl. 2 grams, 10 grams of Stichopus japonicus internal organs. Conventionally Chinese medicine preparation technology makes water decoction, everyone potion every day.
3 therapeutic outcomes
3.1 observation index: 1. start to the time that radioactivity gastric injury symptom occurs from radiotherapy; 2. suspend or abandon the case load of radiotherapy.
3.2 results: result sees attached list. Two groups of patients symptomatic's time of occurrences, suspend or abandon the case load of radiotherapy and compare, difference statistically significant (P < 0.05).
Two groups of patient's incidences of subordinate list compare
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail. But this should not being interpreted as, the scope of the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to the scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition of therapeutic radiation gastritis, water decoction is made, everyone potion every day by xanthorrhiza 30 grams, Rubus lambertianus 30 grams, Radix Stephaniae Japonicae 15 grams, sheep dung fruit 12 grams, Flos Chimonanthi Praecocis 5 grams, Fructus Akebiae 15 grams, dawrf mallow root 25 grams, Rhizoma Polygonati Verticillati 10 grams, Citrus aurantium L. var. amara Engl. 3 grams, 12 grams of Stichopus japonicus internal organs conventionally Chinese medicine preparation technology.
Embodiment 2
A kind of Chinese medicine composition of therapeutic radiation gastritis, water decoction is made, everyone potion every day by xanthorrhiza 25 grams, Rubus lambertianus 25 grams, Radix Stephaniae Japonicae 13 grams, sheep dung fruit 11 grams, Flos Chimonanthi Praecocis 5 grams, Fructus Akebiae 13 grams, dawrf mallow root 22 grams, Rhizoma Polygonati Verticillati 9 grams, Citrus aurantium L. var. amara Engl. 3 grams, 11 grams of Stichopus japonicus internal organs conventionally Chinese medicine preparation technology.
Embodiment 3
A kind of Chinese medicine composition of therapeutic radiation gastritis, water decoction is made, everyone potion every day by xanthorrhiza 20 grams, Rubus lambertianus 20 grams, Radix Stephaniae Japonicae 12 grams, sheep dung fruit 10 grams, Flos Chimonanthi Praecocis 4 grams, Fructus Akebiae 12 grams, dawrf mallow root 20 grams, Rhizoma Polygonati Verticillati 8 grams, Citrus aurantium L. var. amara Engl. 2 grams, 10 grams of Stichopus japonicus internal organs conventionally Chinese medicine preparation technology.
Embodiment 4
A kind of Chinese medicine composition of therapeutic radiation gastritis, water decoction is made, everyone potion every day by xanthorrhiza 15 grams, Rubus lambertianus 15 grams, Radix Stephaniae Japonicae 11 grams, sheep dung fruit 9 grams, Flos Chimonanthi Praecocis 3 grams, Fructus Akebiae 11 grams, dawrf mallow root 18 grams, Rhizoma Polygonati Verticillati 7 grams, Citrus aurantium L. var. amara Engl. 1 gram, 9 grams of Stichopus japonicus internal organs conventionally Chinese medicine preparation technology.
Embodiment 5
A kind of Chinese medicine composition of therapeutic radiation gastritis, water decoction is made, everyone potion every day by xanthorrhiza 10 grams, Rubus lambertianus 10 grams, Radix Stephaniae Japonicae 9 grams, sheep dung fruit 8 grams, Flos Chimonanthi Praecocis 3 grams, Fructus Akebiae 9 grams, dawrf mallow root 15 grams, Rhizoma Polygonati Verticillati 6 grams, Citrus aurantium L. var. amara Engl. 1 gram, 8 grams of Stichopus japonicus internal organs conventionally Chinese medicine preparation technology.
Claims (4)
1. the Chinese medicine composition of a therapeutic radiation gastritis, it is characterised in that be made up of the crude drug of following mass ratio:
Xanthorrhiza 10～30 parts, Rubus lambertianus 10～30 parts, Radix Stephaniae Japonicae 9～15 parts, sheep dung fruit 8～12 parts, Flos Chimonanthi Praecocis 3～5 parts, Fructus Akebiae 9～15 parts, dawrf mallow root 15～25 parts, Rhizoma Polygonati Verticillati 6～10 parts, Citrus aurantium L. var. amara Engl. 1～3 part, 8～12 parts of Stichopus japonicus internal organs.
2. the Chinese medicine composition of therapeutic radiation gastritis as claimed in claim 1, it is characterised in that be made up of the crude drug of following mass ratio:
Xanthorrhiza 15～25 parts, Rubus lambertianus 15～25 parts, Radix Stephaniae Japonicae 11～13 parts, sheep dung fruit 9～11 parts, Flos Chimonanthi Praecocis 3～5 parts, Fructus Akebiae 11～13 parts, dawrf mallow root 18～22 parts, Rhizoma Polygonati Verticillati 7～9 parts, Citrus aurantium L. var. amara Engl. 1～3 part, 9～11 parts of Stichopus japonicus internal organs.
3. the Chinese medicine composition of therapeutic radiation gastritis as claimed in claim 1, it is characterised in that be made up of the crude drug of following mass ratio:
Xanthorrhiza 20 parts, Rubus lambertianus 20 parts, Radix Stephaniae Japonicae 12 parts, sheep dung fruit 10 parts, Flos Chimonanthi Praecocis 4 parts, Fructus Akebiae 12 parts, dawrf mallow root 20 parts, Rhizoma Polygonati Verticillati 8 parts, Citrus aurantium L. var. amara Engl. 2 parts, 10 parts of Stichopus japonicus internal organs.
4. the preparation method of the Chinese medicine composition of therapeutic radiation gastritis as claimed in claim 1, it is characterised in that the Chinese medicinal components of described mass ratio is prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1394629A (en) * | 2002-07-10 | 2003-02-05 | 石淑纯 | Chinese patent medicine for curing gastropathy |
| CN103405482A (en) * | 2013-01-25 | 2013-11-27 | 同济大学丽水中药研究院 | Application of salix leaf and wintersweet extract in preparation of medicines for treating inflammatory bowel diseases and alleviating digestive tract damage caused by chemotherapy drugs |
| CN104758694A (en) * | 2015-04-15 | 2015-07-08 | 邓进巍 | Traditional Chinese medicine composition for treating acute radiation esophagitis |
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2016
- 2016-02-03 CN CN201610084883.8A patent/CN105663677A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1394629A (en) * | 2002-07-10 | 2003-02-05 | 石淑纯 | Chinese patent medicine for curing gastropathy |
| CN103405482A (en) * | 2013-01-25 | 2013-11-27 | 同济大学丽水中药研究院 | Application of salix leaf and wintersweet extract in preparation of medicines for treating inflammatory bowel diseases and alleviating digestive tract damage caused by chemotherapy drugs |
| CN104758694A (en) * | 2015-04-15 | 2015-07-08 | 邓进巍 | Traditional Chinese medicine composition for treating acute radiation esophagitis |
Non-Patent Citations (1)
| Title |
|---|
| 刘永新: "清胃散合芍药甘草汤防治伽玛刀所致急性放射性胃损伤29例", 《河南中医》 * |
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Application publication date: 20160615 |