CN105663174A - Production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid - Google Patents
Production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid Download PDFInfo
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- CN105663174A CN105663174A CN201610012534.5A CN201610012534A CN105663174A CN 105663174 A CN105663174 A CN 105663174A CN 201610012534 A CN201610012534 A CN 201610012534A CN 105663174 A CN105663174 A CN 105663174A
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- ethanol
- eluent
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- pectin
- pectin extraction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/55—Liquid-liquid separation; Phase separation
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The invention discloses a production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid. The technology includes: first step, distilling pectin extracted waste liquid after pectin extraction; second step, adsorbing the liquid subjected to distillation with an adsorption column filled with polyamide or polar macroporous resin as the adsorbent; third step, after adsorption, conducting elution with 30% ethanol, discarding the eluent, then performing elution with a 85% ethanol solution, and collecting the eluent; fourth step, adjusting the pH value of the eluent to 4-5, controlling the temperature at 70-80DEG C for 1-3h; fifth step, centrifuging the raw material of step 4, discarding solid, and retaining the supernatant; and sixth step, performing flash drying to obtain a brown yellow powder product. The technology provided by the invention overcomes the defects of the prior art, broadens the comprehensive utilization value of fruit raw materials, and solves the problems of low extraction rate of bioflavonoid and insecurity in the prior art.
Description
Technical field
The present invention relates to waste liquid recycling technology technical field after pectin extraction, particularly belong to a kind of pectin extraction ethanol devil liquor recovery bioflavonoids production technology.
Background technology
Natural fruit gelatin substance is with Pectin, proto, pectin, the form of pectic acid is widely present in the fruit of plant, root, stem, Ye Zhong, it is a kind of constituent of cell wall, they exist with cellulose, constitute flanking cell interlayer cohesive thing, plant tissue cell is made tightly to be bonded together, pectin can accelerating wound healing, after pectin extraction, its waste material is ethanol waste liquid, wherein bioflavonoids is Secondary Metabolite Production in Plants, they are not single compound, but the multiple general name with similar structures and active substance, because how to be referred to as bioflavonoids in yellow. main Citrin compounds includes flavone, rutacultin, hesperetin etc., belongs to water soluble vitamins, the method for existing main extracting and developing myricetin (myricetin), and it is the method for employing water extraction repeated multiple times recrystallization again. this method yield is very low.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide a kind of pectin extraction ethanol devil liquor recovery bioflavonoids production technology, overcome the deficiencies in the prior art, widen the comprehensive utilization value of fruit raw material, improve prior art and extract that bioflavonoids extraction ratio is low and insecurity problem.
The technical solution used in the present invention is as follows:
A kind of pectin extraction ethanol devil liquor recovery bioflavonoids production technology, the first step, the pectin extraction waste liquid after pectin extraction is distilled;
Second step, the liquid after previous step being distilled adsorbs with being filled with polyamide or the polar macroporous resin adsorption column as adsorbent;
3rd step, after upon adsorption, carries out eluting with 30% ethanol, discards eluent, then carries out eluting with the alcoholic solution of 85%, collects eluent;
It is 4～5 that 4th step eluent regulates pH value, controls temperature 70～80 DEG C, 1～3 hour time;
5th step, is centrifuged the raw material of the 4th step, discards solid containing thing, stays supernatant;
6th step, there is brownish-yellow powder shape finished product in expansion drying.
Described first step distillating extracting liquid introduces concentration and solvent recovering system heating concentration, is reclaimed the ethanol of evaporation by pipeline; Extracting solution forms the mixed liquor of water and flavone after reclaiming ethanol simultaneously, the mixed liquor of water and flavone is introduced special filtration drying all-in-one, is dried in the atmosphere of nitrogen, and baking temperature is 40-60 degree Celsius; Dried yellow substance is exactly last purpose product flavone.
The acid that the 4th described step joint pH value adopts is mineral acid or dilute sulfuric acid.
Compared with the prior art, beneficial effects of the present invention is as follows:
The present invention adopts pectin extraction waste material to carry out recycling, adopts lucifuge, inert gas shielding and temperature to control in extraction process, so the bioflavonoids purity extracted is higher, biological activity keeps; Extract the solvent consumed few; Extraction time is short, so can reduce and produces unnecessary side-product and avoid reducing the biological activity of extract.
Detailed description of the invention
A kind of pectin extraction ethanol devil liquor recovery bioflavonoids production technology, the first step, the pectin extraction waste liquid after pectin extraction is distilled;
Second step, the liquid after previous step being distilled adsorbs with being filled with polyamide or the polar macroporous resin adsorption column as adsorbent;
3rd step, after upon adsorption, carries out eluting with 30% ethanol, discards eluent, then carries out eluting with the alcoholic solution of 85%, collects eluent;
It is 4～5 that 4th step eluent regulates pH value, controls temperature 70～80 DEG C, 1～3 hour time; The acid that the 4th described step joint pH value adopts is mineral acid or dilute sulfuric acid;
5th step, is centrifuged the raw material of the 4th step, discards solid containing thing, stays supernatant;
6th step, there is brownish-yellow powder shape finished product in expansion drying.
Described first step distillating extracting liquid introduces concentration and solvent recovering system heating concentration, is reclaimed the ethanol of evaporation by pipeline; Extracting solution forms the mixed liquor of water and flavone after reclaiming ethanol simultaneously, the mixed liquor of water and flavone is introduced special filtration drying all-in-one, is dried in the atmosphere of nitrogen, and baking temperature is 40-60 degree Celsius; Dried yellow substance is exactly last purpose product flavone; Adopting pectin extraction waste material to carry out recycling, adopt lucifuge, inert gas shielding and temperature to control in extraction process, so the bioflavonoids purity extracted is higher, biological activity keeps; Extract the solvent consumed few; Extraction time is short, so can reduce and produces unnecessary side-product and avoid reducing the biological activity of extract.
The ultimate principle of the present invention, principal character and advantages of the present invention have more than been shown and described. Skilled person will appreciate that of the industry; the present invention is not restricted to the described embodiments; described in above-described embodiment and description is that principles of the invention is described; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements both fall within the claimed scope of the invention. Claimed scope is defined by appending claims and equivalent thereof.
Claims (3)
1. a pectin extraction ethanol devil liquor recovery bioflavonoids production technology, it is characterised in that: the first step, the pectin extraction waste liquid after pectin extraction is distilled;
Second step, the liquid after previous step being distilled adsorbs with being filled with polyamide or the polar macroporous resin adsorption column as adsorbent;
3rd step, after upon adsorption, carries out eluting with 30% ethanol, discards eluent, then carries out eluting with the alcoholic solution of 85%, collects eluent;
It is 4～5 that 4th step eluent regulates pH value, controls temperature 70～80 DEG C, 1～3 hour time;
5th step, is centrifuged the raw material of the 4th step, discards solid containing thing, stays supernatant;
6th step, there is brownish-yellow powder shape finished product in expansion drying.
2. pectin extraction ethanol devil liquor recovery bioflavonoids production technology according to claim 1, it is characterised in that: described first step distillating extracting liquid introduces concentration and solvent recovering system heating concentration, is reclaimed the ethanol of evaporation by pipeline; Extracting solution forms the mixed liquor of water and flavone after reclaiming ethanol simultaneously, the mixed liquor of water and flavone is introduced special filtration drying all-in-one, is dried in the atmosphere of nitrogen, and baking temperature is 40-60 degree Celsius; Dried yellow substance is exactly last purpose product flavone.
3. pectin extraction ethanol devil liquor recovery bioflavonoids production technology according to claim 1, it is characterised in that: the acid that the 4th described step joint pH value adopts is mineral acid or dilute sulfuric acid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610012534.5A CN105663174A (en) | 2016-01-05 | 2016-01-05 | Production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610012534.5A CN105663174A (en) | 2016-01-05 | 2016-01-05 | Production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid |
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| Publication Number | Publication Date |
|---|---|
| CN105663174A true CN105663174A (en) | 2016-06-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610012534.5A Pending CN105663174A (en) | 2016-01-05 | 2016-01-05 | Production technology for recovery of bioflavonoid from pectin extracted ethanol waste liquid |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101817809A (en) * | 2009-12-18 | 2010-09-01 | 烟台安德利果胶有限公司 | Method for producing flavonoids by using pectin-extracted orange peel |
| CN102988457A (en) * | 2012-12-24 | 2013-03-27 | 重庆市中药研究院 | Total flavone extract of lonicera macranthoides leaves, and preparation method and application thereof |
-
2016
- 2016-01-05 CN CN201610012534.5A patent/CN105663174A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101817809A (en) * | 2009-12-18 | 2010-09-01 | 烟台安德利果胶有限公司 | Method for producing flavonoids by using pectin-extracted orange peel |
| CN102988457A (en) * | 2012-12-24 | 2013-03-27 | 重庆市中药研究院 | Total flavone extract of lonicera macranthoides leaves, and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 周春山: ""柚子中果胶和生物类黄酮提取分离工艺及测定研究"", 《中国优秀硕士学位论文全文数据库》 * |
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Address after: 235323 Anhui city of Suzhou province Dangshan County Guan Di Miao Zhen one kilometer north (Highway 101 West Road) Applicant after: Anhui Yu Ning pectin Limited by Share Ltd Address before: 235323 Anhui city of Suzhou province Dangshan County Guan Di Miao Zhen one kilometer north (Highway 101 West Road) Applicant before: Anhui Yuning Biotechnology Co., Ltd. |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160615 |
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| RJ01 | Rejection of invention patent application after publication |