CN105641350A - Traditional Chinese medicine capsules for treating severe scapulohumeral periarthritis - Google Patents

Traditional Chinese medicine capsules for treating severe scapulohumeral periarthritis Download PDF

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CN105641350A
CN105641350A CN201610114261.5A CN201610114261A CN105641350A CN 105641350 A CN105641350 A CN 105641350A CN 201610114261 A CN201610114261 A CN 201610114261A CN 105641350 A CN105641350 A CN 105641350A
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孙宁
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Abstract

The invention discloses traditional Chinese medicine capsules for treating severe scapulohumeral periarthritis. The capsules are prepared from traditional Chinese medicinal materials in parts by weight as follows: 10 parts of cassia twigs, 12 parts of prepared rehmannia roots, 10 parts of spiny aralia, 8 parts of Szechwan lovage rhizomes, 12 parts of spike aletris herbs, 6 parts of Chinese thorowax roots, 6 parts of oysters, 8 parts of burdock, 8 parts of stiff silkworms, 6 parts of Halenia elliptica, 5 parts of Disporum cantoniense, 4 parts of flowers of Mesua ferrea, 3 parts of photinia stems, 3 parts of gunnies, 6 parts of aizoon stonecrop herbs, 4 parts of Chinese ilex leaves, 5 parts of glomeris and 2 parts of ginkgo pollen. Clinical experiments prove that through selection of the proper medicinal materials and ratio of the medicinal materials, the capsules have the significant effect of treating the severe scapulohumeral periarthritis and are safe and free of toxic and side effects.

Description

A kind of Chinese medicinal capsule for treating severe periarthritis of shoulder
Technical field
The present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule for treating severe periarthritis of shoulder.
Background technology
Scapulohumeral periarthritis, also known as congealed shoulder, scapulohumeral periarthritis, is capsula articularis humeri and a kind of degeneration of surrounding tissue, Lymph nodes. Primary disease mostly is chronic disease, and hidden attacking carries out, and how because upper act abduction activity causes pain to begin to be noted, also has the heavier person of making fast progress of pain, and patient is without obvious trauma history, but pathological changes can by traumatic kindling. Initial classical symptom is arthralgia, muscle weakness, moving obstacle. The most obvious symptom of pain, and have persistence, night to increase the weight of and draw convulsive feature. Therefore to occiput, scapular region, upper limb etc. radiate. Shoulder abduction, upper act, inward turning, interior receipts and after to stretch motion substantially limited, patient wears the clothes, undresses and combs one's hair difficulty. Acute stage symptom is especially pronounced, so that patient lies awake all night. The diagnostic criteria of severe periarthritis of shoulder is: anteflexion upper act less than 110 ��, and thumb touches ridge to waist less than 3, abduction less than 45 ��, interior receipts less than 25 ��. Treatment for severe periarthritis of shoulder still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
It is desirable to provide a kind of for Chinese medicinal capsule treating severe periarthritis of shoulder and preparation method thereof, by selecting suitable medical material and proportioning thereof, reach to contribute to the remarkable efficacy for the treatment of severe periarthritis of shoulder and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicinal capsule for treating severe periarthritis of shoulder, is prepared from by the Chinese crude drug of following weight proportion: Ramulus Cinnamomi 10 parts, 12 parts of Radix Rehmanniae Preparata, Radix araliae armatae 10 parts, Rhizoma Chuanxiong 8 parts, lung-wind syndrome grass 12 parts, Radix Bupleuri 6 parts, Concha Ostreae 6 parts, Fructus Arctii 8 parts, Bombyx Batryticatus 8 parts, Halenia elliptica D. Don 6 parts, cantonese fairy bells 5 parts, ferreous mesua spend 4 parts, 3 parts of stone Fructus Piperis, gunny 3 parts, Herba Sedi Aizoon 6 parts, Folium Ilicis Purpureae 4 parts, roll 5 parts of mountain pearl, 5 parts of long sequence Moghania fluminalis(C. B. Clarke) Li tree, Semen Ginkgo pollen 2 parts.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Roll the entirety that mountain pearl [source] is Glomeridae animal glomeris nipponica Kishida. [nature and flavor] acrid in the mouth, hot in nature. [function cures mainly] dispelling wind and removing obstruction in the collateral, eliminating stasis to stop pain. Cure mainly rheumatic arthralgia, muscle arteries and veins contracture, traumatic injury. Fracture swells and ache.
The root that gunny [source] is ranunculaceae plant Aconitum sinomontanum Nakai. [nature and flavor] bitter in the mouth, hot in nature, poisonous. [function cures mainly] expelling wind and removing dampness, regulating QI to relieve pain, promoting blood circulation and detumescence. Cure mainly rheumatic arthralgia, arthralgia.Traumatic injury, stomachache, distension and fullness of the chest and abdomen, furuncle.
Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi. [nature and flavor] acrid, sweet, warm. [return through] GUIXIN, lung, bladder warp. [function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins. For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Rehmanniae Preparata [source] this product is the Preparation process product of Radix Rehmanniae. [nature and flavor] are sweet, tepor. [return through] returns liver, kidney channel. [function cures mainly] nourishing YIN and supplementing blood, benefit essence fills out marrow. For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizziness, tinnitus, early whitening of beard and hair.
Radix araliae armatae [source] is the root of Araliaceae Herba Damnacanthi wood, root bark or branch and leaf. [nature and flavor] acrid in the mouth, warm in nature, nontoxic. [function cures mainly] dissipating blood stasis for subsidence of swelling, expelling wind and removing dampness. Controlling traumatic injury, rheumatic arthralgia, stomachache, diarrhoea, dysentery, leucorrhea, carbuncle, furuncle swells.
The dry rhizome of Rhizoma Chuanxiong [source] samphire Rhizoma Chuanxiong. [nature and flavor] are pungent, temperature. [return through] returns liver, gallbladder, pericardium channel. [function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.
The herb that lung-wind syndrome grass [source] is samphire Herba Hydrocotyles. [nature and flavor] toil, cold. [function cures mainly] heat clearing away, diuresis, detumescence, removing toxic substances. Harnessing the Yellow River subcutaneous ulcer, dysentery, gonorrhea, dysuria, corneal nebula, larynx swells, carbuncle furuncle, traumatic injury congestive edema. For acute icterohepatitis, acute nephritis, pertussis, lithangiuria, tinea pedis, herpes zoster, conjunctivitis, erysipelas.
Fructus Arctii [source] this product is the dry mature fruit of feverfew Fructus Arctii. [nature and flavor] are pungent, bitter, cold. [return through] attaches to the lung and stomach meridians. [function cures mainly] dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.
The larva of Bombyx Batryticatus [source] Bombycidae insecticide bombyx mori infects muscardine and ossified dry Scorpio. [nature and flavor] acrid in the mouth; Salty; Property is put down. [return through] liver; Lung; Stomach warp. [function cures mainly] expellings wind and relieving convulsion; Dissipating phlegm and resolving masses; Resolving toxin and disinhibiting the throat. Main infantile convulsion is twitched; Middle air port eye is oblique; Migraine and general headache; Laryngopharynx swelling and pain; Scrofula; Mumps; Rubella; Sore.
The dry root of Radix Bupleuri [source] umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii.. [function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating. For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official prolapses, proctoptosis.
The shell of the long Concha Ostreae of Concha Ostreae [source] Ostreidae animal. [nature and flavor] are salty, are slightly cold. [return through] returns liver, gallbladder, kidney channel. [function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.
The dry root of the Radix Astragali [source] leguminous plant Radix Astagali. [nature and flavor] are sweet, temperature. [return through] returns lung, spleen channel. [function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
The wounded in the battle herb that Halenia elliptica D. Don [source] is gentianaceae plant Halenia elliptica D. Don. [nature and flavor] bitter in the mouth, cold in nature. [function cures mainly] presses down association's day, heat clearing away, cures the wound, stomach invigorating. Cure mainly association's day heat, liver-heat, plague fever, internal organs heat.
The root and rhizome that cantonese fairy bells [source] is liliaceous plant cantonese fairy bells. [nature and flavor] bitter in the mouth, property is cold. [function cures mainly] nourishing the lung to arrest cough, spleen invigorating removing food stagnancy. Cure mainly cough with asthma, sputum mixed with blood, discharging fresh blood stool, dyspeptic abdominal distention.
Ferreous mesua spends [source] for the flower of Garcinia maingayii ferreous mesua.[nature and flavor] two grades are xeothermic, bitter in the mouth. [function cures mainly] is raw dry raw hot, temperature compensation heart, the happy will of the refreshing heart, warm-up tonifying YANG, and dampness mends stomach, antidiarrheal, holds back wound, the hemorrhoid that disappear of stopping blooding. Cure mainly raw property or lymphatic temperament disease, as cold having a guilty conscience, depression, neurasthenia, coldness of the body YANG excess, moist insufficiency of stomach, diarrhoea and various wet wound, bleeding hemorrhoids etc.
Stem and leaf that stone Fructus Piperis [source] is Piperaceae phytobezoar Caulis et Folium piperis or Herb. [nature and flavor] taste is numb, peppery, hot in nature. [function cures mainly] wind-damp dispelling, strong waist knee joint, kidney invigorating and YANG supporting, relieving cough and asthma, promoting blood circulation and stopping pain. Cure mainly anemofrigid-damp arthralgia, soreness of waist and knee joint, sexual impotence, cough and asthma, dysmenorrhea, treating swelling and pain by traumatic injury.
Root that long sequence Moghania fluminalis(C. B. Clarke) Li tree [source] is precipice, leguminous plant Simao bean and leaf. [nature and flavor] sweet in the mouth, micro-fiber crops. Property is put down. [function cures mainly] is except wind diuretic. ventilation pain relieving. Main arthralgia due to wind-cold-dampness disease of being in harmony, limbs joint is ached, joint stuffiness, traumatic injury.
Semen Ginkgo pollen [source] is the Semen Ginkgo pollen through micronizing breaking cellular wall Yu anti-oxidant treatment. Containing substantial amounts of flavone in [effect] Semen Ginkgo pollen, lactone isoreactivity material, the cardiovascular disease such as hypertension, hyperlipidemia there is is certain therapeutic effect. Because it contains a kind of dynamical bioactive substance, the metabolism of human tissue organ can be improved, strengthen cardiovascular function, slow down aging, can be used as promoting the reinforcing agent of human physical power and endurance.
The wounded in the battle herb that Halenia elliptica D. Don [source] is gentianaceae plant Halenia elliptica D. Don. [nature and flavor] bitter in the mouth, cold in nature. [function cures mainly] presses down association's day, heat clearing away, cures the wound, stomach invigorating. Cure mainly association's day heat, liver-heat, plague fever, internal organs heat.
Herba Sedi Aizoon [source] medical material Ji Yuan: for crassulaceae plants Herba sedi kamtschatici, the root of horizontal root Herba sedi kamtschatici or herb. [nature and flavor] put down; Sweet; Micro-acid. [return through] heart; Liver; Spleen channel. [function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances. Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
Folium Ilicis Purpureae [another name] Folium Ilicis Purpureae (Jiangsu). [source] is the blade of holly plant Ilicis Purpureae. [chemical analysis] leaf is containing two kinds of antipathogenic compositions, and one of them is protocatechuic acid, separately containing volatile oil, flavonoid. [nature and flavor] are pained, cold. [function cures mainly] controls scald, ulcer disunion of a specified duration, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, bacillary dysentery, and traumatic hemorrhage freezes chilblain, chaps.
The root that Radix vitis romanetii [source] is vitaceae trilobated leaf Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae). [nature and flavor] bitter in the mouth, puckery, property is cold. [function cures mainly] promoting blood circulation to remove obstruction in the collateral, hemostasia and promoting granulation, removing toxic substances and promoting subsidence of swelling. Cure mainly rheumatic arthralgia, tumbling down congestive edema, wound hemorrhage, scald, carbuncle sore.
Herb that the high foot red sorrel of Herba Brediae Amoenae [another name], HUOXUEDAN [source] are Melastomateae plants Herba Brediae Amoenae and root. [nature and flavor] put down. [function cures mainly] expelling wind and removing dampness, promoting blood flow to regulate menstruation.
The calculus grass swollen cylinder of [popular name] big gun, Radix et Rhizoma Thalictri, sheep milk, the Yanshan Mountain is red, sheep tail chicken tail careless, yellow, toilet is colored, Mel is colored, big gun is swollen flower, rock trumpet flower. The band rhizome herb that [source] is Bignoniaceae plant Herba Melicae Scabrosae. [nature and flavor] bitter in the mouth, micro-pungent, property is cold. [function cures mainly] invigorating spleen to remove dampness, promoting flow of QI and blood. Cure mainly and have loose bowels, dysentery, stomachache, hypochondriac pain, rheumatalgia. Menoxenia.Carbuncle, fracture.
The present invention compared with prior art, has the advantages that
1, severe periarthritis of shoulder cure rate is high and safe without toxic side effect for treatment for Chinese medicine preparation of the present invention, and can prevent related complication. Between formula medical material, compatibility is rigorous, produced synergistic function after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, it is important to note that and selects the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect. Wherein: Fructus Arctii, Bombyx Batryticatus two medicine, control the key medicine of expectorant eliminating stagnation for it, Fructus Arctii: cool in nature, acrid in the mouth is bitter, eliminating phlegm for diminishing swelling, current twelve channels and collaterals; " medicineization justice " says it: " can rise and can drop, cure mainly top wind-phlegm. " Bombyx Batryticatus: property is flat, acrid in the mouth is salty, expelling wind to relieve convulsion, dissipating phlegm and resolving masses. " book on Chinese herbal medicine analyze mentally record " is said it and " is controlled the wind-phlegm of domination of damp pathogen ... rob phlegm-damp and dissipate liver-wind. " thus, the application of Fructus Arctii, Bombyx Batryticatus, both compatibilities can pass through the twelve regular channels, open brokenly expectorant knot, to lead its knot stagnant, declare and reach QI and blood, relieving rigidity of joints. Radix Bupleuri Concha Ostreae two medicine mutually 5, had both declared not reaching of yang-energy, again not the relaxing of the cloudy gas of exhibition, can snorkeling sun, hold back Kidney-Yin, soothing liver-QI is strongly fragrant, softening the hard mass addiction, from becoming the wonderful of collaborative, two-ways regulation. Radix Bupleuri has reinforcement non-specific immunity, Concha Ostreae also has the effect promoting immunologic function to strengthen, the synergism of this same tropism, enhances body anti-infection ability, help spend with Halenia elliptica D. Don, cantonese fairy bells, ferreous mesua, the conditioning the five internal organs such as stone Fructus Piperis, wherein Halenia elliptica D. Don promoting digestion and protecting liver, cantonese fairy bells lung moistening spleen invigorating, ferreous mesua spends temperature compensation heart, stone Fructus Piperis kidney invigorating and YANG supporting, take spleen, lung, the heart, liver, kidney QI of five ZANG-organs the moon respectively into account, reduce concurrent syndrome, separately strengthen immunity with Semen Ginkgo pollen. By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, reach medicine to remove to disease, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study is theoretical, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reaches the purpose for the treatment of both the principal and secondary aspects of a disease, clinic popularization and application.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: Ramulus Cinnamomi 10 grams, 12 grams of Radix Rehmanniae Preparata, Radix araliae armatae 10 grams, Rhizoma Chuanxiong 8 grams, lung-wind syndrome grass 12 grams, Radix Bupleuri 6 grams, Concha Ostreae 6 grams, Fructus Arctii 8 grams, Bombyx Batryticatus 8 grams, Halenia elliptica D. Don 6 grams, cantonese fairy bells 5 grams, ferreous mesua spend 4 grams, 3 grams of stone Fructus Piperis, gunny 3 grams, Herba Sedi Aizoon 6 grams, Folium Ilicis Purpureae 4 grams, roll 5 grams of mountain pearl, 5 grams of long sequence Moghania fluminalis(C. B. Clarke) Li tree, Semen Ginkgo pollen 2 grams.
Preparation method is: mixes after above-mentioned medical material is removed impurity respectively, sends in drying baker and dry at 120 DEG C of temperature, be ground into 100-130 order smalls, presses 0.5g/ grain and loads capsule, be finished product after disinfection by ultraviolet light.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal.
Clinical data:
1, case selection:
In the severe periarthritis of shoulder patient 46 example clinical observation of my institute's diagnosis and treatment since selecting 2013, clinical symptoms all meets severe periarthritis of shoulder diagnosis and treatment standard. Patient is randomly divided into treatment group and matched group two groups, treatment group 33 example, matched group 13 example.Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 7 days, it is 1 course for the treatment of.
Matched group adopts conventional western medicine Comprehensive Treatment, and the course for the treatment of is with treatment group.
2 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) cure: shoulder pain disappears, and functional rehabilitation is normal.
(2) take a turn for the better: pain disappears, and upper act reaches more than 135 degree, and backhand can touch more than waist 5 spinous process, but function is not exclusively same as strong side.
(3) do not heal: pain is improved inconspicuous, and dysfunction is without improvement.
4, result:
Selecting in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 26 examples, take a turn for the better 6 examples, and do not heal 1 example, cure rate 78.8%, total effective rate 97.0%.
Curing 7 examples in matched group, take a turn for the better 3 examples, and do not heal 3 examples, cure rate 53.8%, total effective rate 76.9%.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Embodiment 2
Weigh: Ramulus Cinnamomi 10 grams, 12 grams of Radix Rehmanniae Preparata, Radix araliae armatae 10 grams, Rhizoma Chuanxiong 8 grams, Radix vitis romanetii 12 grams, Fructus Arctii 12 grams, Bombyx Batryticatus 12 grams, Halenia elliptica D. Don 6 grams, cantonese fairy bells 5 grams, ferreous mesua spend 4 grams, 3 grams of stone Fructus Piperis, gunny 3 grams, calculus grass 15 grams, Herba Sedi Aizoon 6 grams, Folium Ilicis Purpureae 4 grams, roll 5 grams of mountain pearl, 5 grams of long sequence Moghania fluminalis(C. B. Clarke) Li tree, Herba Brediae Amoenae 6 grams, Semen Ginkgo pollen 2 grams.
Preparation method is: mixes after above-mentioned medical material is removed impurity respectively, sends in drying baker and dry at 120 DEG C of temperature, be ground into 100-130 order smalls, presses 0.5g/ grain and loads capsule, be finished product after disinfection by ultraviolet light.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal.
In the severe periarthritis of shoulder patient 13 example clinical observation of my institute's diagnosis and treatment, selecting the embodiment of the present invention 2 Chinese medicinal capsule to treat, cure 11 examples after 15 days, take a turn for the better 1 example, and do not heal 1 example, cure rate 84.6%, total effective rate 92.3%.
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not the restriction to embodiments of the present invention. Relevant Chinese medicine and pharmacology thereof all can be obtained by existing open source literature and network. For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description. Here cannot all of embodiment be given exhaustive. Every belong to apparent change that technical scheme extended out or the variation row still in protection scope of the present invention.

Claims (1)

1. the Chinese medicinal capsule being used for treating severe periarthritis of shoulder, it is characterized in that, the Chinese crude drug of following weight proportion be prepared from: Ramulus Cinnamomi 10 parts, 12 parts of Radix Rehmanniae Preparata, Radix araliae armatae 10 parts, Rhizoma Chuanxiong 8 parts, lung-wind syndrome grass 12 parts, Radix Bupleuri 6 parts, Concha Ostreae 6 parts, Fructus Arctii 8 parts, Bombyx Batryticatus 8 parts, Halenia elliptica D. Don 6 parts, cantonese fairy bells 5 parts, ferreous mesua spend 4 parts, 3 parts of stone Fructus Piperis, gunny 3 parts, Herba Sedi Aizoon 6 parts, Folium Ilicis Purpureae 4 parts, roll 5 parts of mountain pearl, Semen Ginkgo pollen 2 parts.
CN201610114261.5A 2016-03-01 2016-03-01 Traditional Chinese medicine capsules for treating severe scapulohumeral periarthritis Withdrawn CN105641350A (en)

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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
朱震云等: "自拟玉屏风散加减方结合中药外敷对肩关节周围炎的疗效分析", 《中外医疗》 *

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