CN105636598B - 包含胞外基质组织材料和成骨蛋白的产品 - Google Patents

包含胞外基质组织材料和成骨蛋白的产品 Download PDF

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Publication number
CN105636598B
CN105636598B CN201480056459.1A CN201480056459A CN105636598B CN 105636598 B CN105636598 B CN 105636598B CN 201480056459 A CN201480056459 A CN 201480056459A CN 105636598 B CN105636598 B CN 105636598B
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extracellular matrix
tissue material
composition
matrix tissue
morphogenic protein
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Chinese (zh)
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CN105636598A (zh
Inventor
S·L·瓦拉斯
A·F·泰勒
S·查利伯斯
C·M·斯泰因哈特
N·E·佩尔诺特
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Muffin Inc
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Muffin Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
CN201480056459.1A 2013-09-02 2014-09-02 包含胞外基质组织材料和成骨蛋白的产品 Active CN105636598B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361872827P 2013-09-02 2013-09-02
US61/872,827 2013-09-02
PCT/US2014/053671 WO2015031882A1 (en) 2013-09-02 2014-09-02 Products comprising an extracellular matrix tissue material and osteogenic protein

Publications (2)

Publication Number Publication Date
CN105636598A CN105636598A (zh) 2016-06-01
CN105636598B true CN105636598B (zh) 2021-07-23

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CN201480056459.1A Active CN105636598B (zh) 2013-09-02 2014-09-02 包含胞外基质组织材料和成骨蛋白的产品

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Country Link
US (2) US20150065425A1 (enExample)
EP (1) EP3041483B1 (enExample)
JP (2) JP2016529057A (enExample)
CN (1) CN105636598B (enExample)
CA (1) CA2923002C (enExample)
WO (1) WO2015031882A1 (enExample)

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CA2988778A1 (en) * 2015-06-09 2016-12-15 Orthocyte Corporation Osteogenic graft forming unit
WO2017003877A1 (en) * 2015-06-30 2017-01-05 Lattice Biologics Inc. Modified extracellular matrix for enhanced stem cell homing and engraftment
CN106913908B (zh) * 2015-12-25 2020-05-26 北京瑞健高科生物科技有限公司 一种具有结构记忆特性的细胞生长支架
CN107913436A (zh) * 2016-10-09 2018-04-17 刘英芹 作用于伤残组织原位的骨与软组织同步再生诱导剂
KR20180133172A (ko) * 2017-06-05 2018-12-13 주식회사 티앤알바이오팹 골 이식재 고정용 주사형 접착제 조성물의 제조방법 및 이를 통해 제조된 골 이식재 고정용 주사형 접착제 조성물
US11464888B2 (en) 2017-06-12 2022-10-11 Warsaw Orthopedic, Inc. Moldable formulations containing an oxysterol in an acellular tissue matrix
US20190091372A1 (en) * 2017-09-27 2019-03-28 Globus Medical, Inc. Coagulum-based biomaterial compositions and methods thereof
CN113226386A (zh) * 2018-12-25 2021-08-06 奥梭瑞贝斯株式会社 具有由多种电纺纤维形成的棉絮状结构的骨再生材料
CN111500533B (zh) * 2019-01-31 2024-07-16 华东理工大学 干细胞发生器及其构建方法
CN111494711B (zh) 2019-01-31 2023-06-23 华东理工大学 干细胞发生器产生的干细胞用于治疗造血损伤
CN110585484A (zh) * 2019-10-12 2019-12-20 上海白衣缘生物工程有限公司 一种骨组织用复合骨粉及其制备方法和应用
CN114984327B (zh) * 2022-06-18 2023-04-25 广州医科大学 一种复合骨缺损填补剂及其制备方法
CN116370715B (zh) * 2023-05-10 2024-05-17 首都医科大学附属北京口腔医院 一种含他汀类药物的可塑形多孔生物复合骨充填材料及制备方法
CN120189435A (zh) * 2023-12-04 2025-06-24 桂林医学院 关节结构重建诱导剂及其使用方法和用途

Citations (3)

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EP1312383A2 (en) * 2001-11-20 2003-05-21 Ed Geistlich Söhne AG Für Chemische Industrie Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage
WO2005097219A2 (en) * 2004-03-31 2005-10-20 Cook Incorporated Ecm-based graft material
WO2009114535A2 (en) * 2008-03-10 2009-09-17 Marfly 2, Lp Bone paste composition

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CA2192103C (en) * 1994-06-06 2002-02-05 Arnold I. Caplan Biomatrix for tissue regeneration
US6180606B1 (en) * 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
US5755791A (en) * 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
DE19816858A1 (de) * 1998-04-16 1999-10-21 Merck Patent Gmbh Tricalciumphosphathaltige Biozementpasten mit Kohäsionspromotoren
US9107751B2 (en) * 2002-12-12 2015-08-18 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials
US7105001B2 (en) * 2003-05-21 2006-09-12 Mandelbaum Jon A Surgical method and composition utilizing submucosal tissue to prevent incisional hernias
EP1964583A1 (en) * 2007-02-09 2008-09-03 Royal College of Surgeons in Ireland Process for producing a collagen/hydroxyapatite composite scaffold
CN101980714A (zh) * 2008-03-31 2011-02-23 奥古斯蒂努斯·巴德 借助干细胞或骨髓细胞进行组织再生的方法和组合物
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WO2015031809A1 (en) * 2013-09-02 2015-03-05 Muffin Incorporated Cell-seeded compositions and methods useful for treating bone regions

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EP1312383A2 (en) * 2001-11-20 2003-05-21 Ed Geistlich Söhne AG Für Chemische Industrie Resorbable extracellular matrix containing collagen I and collagen II for reconstruction of cartilage
WO2005097219A2 (en) * 2004-03-31 2005-10-20 Cook Incorporated Ecm-based graft material
WO2009114535A2 (en) * 2008-03-10 2009-09-17 Marfly 2, Lp Bone paste composition

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
US9993580B2 (en) 2018-06-12
EP3041483A4 (en) 2017-05-03
CN105636598A (zh) 2016-06-01
JP2016529057A (ja) 2016-09-23
CA2923002A1 (en) 2015-03-05
JP6882361B2 (ja) 2021-06-02
US20150065425A1 (en) 2015-03-05
EP3041483A1 (en) 2016-07-13
US20160263282A1 (en) 2016-09-15
JP2019122410A (ja) 2019-07-25
WO2015031882A1 (en) 2015-03-05
EP3041483B1 (en) 2021-05-26
CA2923002C (en) 2022-12-13

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