CN105622446A - Calcium aspartate synthesis method - Google Patents
Calcium aspartate synthesis method Download PDFInfo
- Publication number
- CN105622446A CN105622446A CN201410598035.XA CN201410598035A CN105622446A CN 105622446 A CN105622446 A CN 105622446A CN 201410598035 A CN201410598035 A CN 201410598035A CN 105622446 A CN105622446 A CN 105622446A
- Authority
- CN
- China
- Prior art keywords
- calcium
- distilled water
- calcium aspartate
- acid
- synthesis method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention relates to a calcium aspartate synthesis method and belongs to the field of food additives and preparation methods thereof. The calcium aspartate synthesis method comprises mixing calcium hydrate and aspartic acid according to a mass ratio of 3: 10, adding distilled water into the mixture, wherein the use amount of the distilled water is 10 times that of the mixture, carrying out stirring heating to a temperature of 65-85 DEG C, carrying out a reaction process under control of pH in a range of 8-9 for 20-30min, filtering the reaction product, concentrating and crystallizing the filtrate, and drying and crushing the crystals to obtain calcium aspartate powder. The calcium aspartate synthesis method has simple processes and good operationality, is suitable for industrial production and can produce high quality products. A determination result shows that the calcium aspartate has purity of 99.2% and has indexes satisfying the calcium aspartate food-grade standards.
Description
Technical field
The present invention relates to the synthetic method of a kind of calcium aminosuccinic acid, belong to food additive and preparation method thereof field.
Background technology
Calcium is one of mineral that in human body, content is the abundantest, is requisite element in our life. Without it, the mankind cannot remain strong skeleton and tooth. In human body, the doped calcium of about BBC is local in the two. Additionally, calcium also helping heart, neural, other system of muscle and human body runs well. It is reported, a large amount of use caffeine can reduce the calcium level in human body; Often the edible food containing high protein, excessively takes in sodium, and phosphorus (passes through soda pop), ethanol and the antacid containing aluminum, also all can cause that the calcium level in Excreta reduces. It is true that the statistics according to World Health Organization (WHO), many Americans to the consumption of calcium lower than in order to keep bone health, the half level of required absorption calcium amount. As for China, situation is then even more serious. In general, food is best calcium source. But those only can not meet the people of calcium demand by food, and calsium supplement is required.
Calcium aminosuccinic acid is the one in amino acid calcium, and it is a kind of calcium of organic acid with biologically active structure. Its steady chemical structure, good water solubility, human absorptivity is high, belongs to the product of latest generation in calcium-nutrition intensifying agent now. In at present relatively famous calsium supplement, such as " god's calcium drink ", " calcium gold ", " happy power " all mainly contains the composition of calcium aminosuccinic acid. So, the synthesis of research calcium aminosuccinic acid is significantly.
Summary of the invention
It is desirable to provide a kind of technique is simple, workable, it is adaptable to the synthetic method of industrialized production and the high calcium aminosuccinic acid of product quality.
The synthetic method of described calcium aminosuccinic acid, comprises the following steps:
It is after calcium hydroxide and aspartic acid are mixed by 3:10 in mass ratio, add in 10 times of distilled water and be stirred and heated to 65-85 DEG C, and control pH value between 8-9, react 20-30min, filter by filtrate concentration, crystallization, dry, pulverize powder is calcium aminosuccinic acid.
Preferably, calcium hydroxide of the present invention is food stage, carries out pretreatment before the reaction, pre-treatment step is as follows: be dissolved in distilled water by calcium hydroxide, make supersaturated solution, stir 20 minutes, stand, until upper solution clarification, clear liquid is toppled over removing, then adds distilled water again, so in triplicate, precipitation is put vacuum drying at low temperatures, puts in agent bottle standby.
It is furthermore preferred that aspartic acid of the present invention is food stage, carry out pretreatment before the reaction, pre-treatment step is as follows: is dissolved in distilled water by aspartic acid, makes supersaturated solution, then when stirring, it is heated to boiling, so as to be completely dissolved, uses rapidly buchner funnel sucking filtration while hot, then, then by filtrate heat, concentrating under reduced pressure, crystallization, dry, the crystal prepared after recrystallization, put in reagent bottle standby.
In order to ensure the quality of fabricated food level calcium aminosuccinic acid, especially for removing possible heavy metal ion and other mechanical admixture in raw material, therefore carry out certain pretreatment to calcium hydroxide (food stage) with to aspartic acid (food stage).
It is simple, workable that synthetic method of the present invention has technique, suitable in industrialized production and product quality high, after measured, the calcium aminosuccinic acid purity that this method prepares is 99.2%, and indices all meets a day ammonia winter propylhomoserin calcium food grade standard.
Detailed description of the invention
Embodiment one:
Take food-grade calcium hydroxide 1000g to be dissolved in 1000ml distilled water, make supersaturated solution, stir 20min, stand, until upper solution clarification, clear liquid is toppled over removing, then adds 1000ml distilled water again, so in triplicate, precipitation is put vacuum drying at low temperatures, puts in agent bottle standby.
Take food grade aspartic acid 1000g to be dissolved in 1000ml distilled water, make supersaturated solution, then when stirring, it is heated to boiling, so as to be completely dissolved, use rapidly buchner funnel sucking filtration while hot, then, again filtrate is heated, concentrating under reduced pressure, crystallization, dry, the crystal prepared after recrystallization, puts in reagent bottle standby.
After taking above-mentioned calcium hydroxide 150g and aspartic acid 500g mixing, add in 6500ml distilled water and be stirred and heated to 80 DEG C, and control pH value between 8.5, react 25min, filter by filtrate concentration, crystallization, dry, pulverize powder is calcium aminosuccinic acid 530g, after measured, this product purity is 99.2%.
Embodiment two: product quality is as follows:
From upper table, the indices of the synthesized sky ammonia winter propylhomoserin calcium prepared of the present invention all meets a day ammonia winter propylhomoserin calcium food grade standard.
Claims (3)
1. the synthetic method of calcium aminosuccinic acid, comprises the following steps:
It is after calcium hydroxide and aspartic acid are mixed by 3:10 in mass ratio, add in 10 times of distilled water and be stirred and heated to 65-85 DEG C, and control pH value between 8-9, react 20-30min, filter by filtrate concentration, crystallization, dry, pulverize powder is calcium aminosuccinic acid.
2. the synthetic method of calcium aminosuccinic acid as claimed in claim 1, it is characterised in that described calcium hydroxide is food stage, carries out pretreatment before the reaction, pre-treatment step is as follows: be dissolved in distilled water by calcium hydroxide, make supersaturated solution, stir 20 minutes, stand, until upper solution clarification, clear liquid is toppled over removing, then adds distilled water again, so in triplicate, precipitation is put vacuum drying at low temperatures, puts in agent bottle standby.
3. the synthetic method of calcium aminosuccinic acid as claimed in claim 1, it is characterised in that described aspartic acid is food stage, carries out pretreatment before the reaction, pre-treatment step is as follows: is dissolved in distilled water by aspartic acid, makes supersaturated solution, then when stirring, it is heated to boiling, so as to be completely dissolved, uses rapidly buchner funnel sucking filtration while hot, then, then by filtrate heat, concentrating under reduced pressure, crystallization, dry, the crystal prepared after recrystallization, put in reagent bottle standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410598035.XA CN105622446A (en) | 2014-10-31 | 2014-10-31 | Calcium aspartate synthesis method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410598035.XA CN105622446A (en) | 2014-10-31 | 2014-10-31 | Calcium aspartate synthesis method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105622446A true CN105622446A (en) | 2016-06-01 |
Family
ID=56037835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410598035.XA Pending CN105622446A (en) | 2014-10-31 | 2014-10-31 | Calcium aspartate synthesis method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105622446A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110511155A (en) * | 2019-08-15 | 2019-11-29 | 河北力维素科技有限公司 | A kind of preparation method of asparatate mineral sequestration object and its salt |
-
2014
- 2014-10-31 CN CN201410598035.XA patent/CN105622446A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110511155A (en) * | 2019-08-15 | 2019-11-29 | 河北力维素科技有限公司 | A kind of preparation method of asparatate mineral sequestration object and its salt |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102775340B (en) | Method for synthesizing pyroglutamic calcium glutamate with shells serving as calcium sources | |
| CN104041791A (en) | Method for producing edible salt from sea water through industrial process and processing device of edible salt | |
| CN108552447A (en) | A kind of lemonade and preparation method thereof | |
| JP2005515952A (en) | Method for recovering low sodium salt from bitter juice | |
| CN101215231A (en) | Method for preparing calcium salt by using shell as raw material | |
| CN101747179B (en) | Method for preparing citric acid malic acid calcium | |
| CN103936034B (en) | Preparation method of high-purity sodium iodide powder | |
| CN103549572A (en) | Medlar fruit juice beverage and production process thereof | |
| CN108726499B (en) | Food-grade calcium hydrophosphate and preparation method thereof | |
| CN101161099A (en) | A method for preparation of fresh vermicelli | |
| CN110078192A (en) | A kind of mineral water and preparation method thereof | |
| CN107216264B (en) | A kind of processing method of l-Alanine waste liquor | |
| CN105622446A (en) | Calcium aspartate synthesis method | |
| CN105566098A (en) | Method for combined production of high purity crystalline calcium acetate and waterless calcium acetate | |
| CN104262132A (en) | Method for preparing calcium propionate from eggshell | |
| CN103880692A (en) | Production method of irony food nutritive fortifier sodium iron ethylenediamine tetraacetate | |
| CN104557822A (en) | Refinement method of vitamin C sodium salt | |
| CN102219767B (en) | Method for preparing calcium ascorbate by utilizing shrimp shells | |
| CN103951553A (en) | Calcium malate prepared by adopting abalone shell as raw material and preparation method of calcium malate | |
| RU2613279C1 (en) | Method for processing sea algae | |
| CN108658039B (en) | Water hydrogen production material and preparation method and application thereof | |
| CN104086396A (en) | Shell-source citric acid complexed calcium product and preparation method | |
| CN104086397B (en) | Shell source oxysuccinic acid complexing calcium product and preparation method | |
| CN104291367B (en) | A kind of production method of magnesium sulfate monohydrate | |
| CN1051898A (en) | The method for making of refined natural salt |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160601 |