CN105616651A - Chinese herbal preparation for treating rheumatism, arthralgia and myalgia and preparing method thereof - Google Patents
Chinese herbal preparation for treating rheumatism, arthralgia and myalgia and preparing method thereof Download PDFInfo
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Abstract
The invention relates to the technical field of rheumatism, arthralgia and myalgia, in particular to a Chinese herbal preparation for treating rheumatism, arthralgia and myalgia and a preparing method thereof. The Chinese herbal preparation is prepared from tinospora sinensis, beautiful millettia root, starflowerlike loosestrife root or herb, philippine flemingia root, periploca forrestii schltr and spinyleaf pricklyash root. The raw materials are mixed, either baijiu or ethyl alcohol is added for dynamic soaking at the normal temperature, and then the Chinese herbal preparation is obtained. The Chinese herbal preparation can be applied to patients suffering from rheumatism, rheumatoid, arthritis, arthralgia and myalgia, and complete healing can be realized; the Chinese herbal preparation can also act on traumatic injuries and soft tissue wounds, the treatment effect is good, and the effective rate is 100%; furthermore, the consolidating treatment effect can be realized in the medicating process, and relapse is avoided.
Description
Technical field
The present invention relates to rheumatism arthralgia and myalgia technical field, especially one treats rheumatism arthralgia and myalgia Chinese medicine preparation and its preparation method.
Background technology
Rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia are common infringement joint, bone, muscle, blood vessels and are main disease about soft tissue or reticular tissue, and wherein majority is autoimmune disorder. Morbidity is much more hidden and slow, and the course of disease is longer, and mostly has genetic predisposition. Patient not only suffers misery, but also loses work capacity, even causes life to take care of oneself. China is in treatment rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia for thousands of years, have accumulated rich experience.
Along with, in constantly the carrying out of the research and development to traditional Chinese medicinal material raw materials, traditional traditional Chinese medical science and grass doctor disclose many new formulas, and some formulas have made preparation, and commercialization. such as rheumatism muscles and bones recovering capsule (the accurate word Z20036078 of traditional Chinese medicines), rheumatic cold pain sheet (the accurate word Z12020022 of traditional Chinese medicines), Heiguteng exract chases after wind collaterals-activating capsule (the accurate word Z20025279 of traditional Chinese medicines), bones and muscles pain due to rheumatism pastes (Jitong defends strong card No. 0003rd, word [2005]), application number be 200810064385 " one treats arthralgia and myalgia, the spray agent of rheumatism class pain and its preparation method ", application number is " a kind of plaster and its preparation method treating rheumatism and arthralgia and myalgia " of 201310081424, application number is " a kind of medicinal liquor and its preparation method treating rheumatic arthralgia and myalgia " of 201510047348 etc.
However, the traditional Chinese medicine ingredients proportioning of various treatment rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia is had nothing in common with each other by it, and its result for the treatment of that can reach also is not identical, and, dosage for diseases such as rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia is bigger, and traditional Chinese medicinal material raw materials is owing to himself side effect is little, result for the treatment of preferably feature so that be applied to by traditional Chinese medicinal material raw materials continual exploitation in order to inevitable developing direction.
Summary of the invention
The above-mentioned technical problem existed to solve in prior art, the present invention provides one to treat rheumatism arthralgia and myalgia Chinese medicine preparation and its preparation method.
It is achieved particular by following technical scheme:
One treats rheumatism arthralgia and myalgia Chinese medicine preparation, and the material composition of said preparation is Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii; And after above-mentioned raw materials is mixed, add the one in white wine or alcohol and carry out dynamic soak at room temperature and become.
One treats rheumatism arthralgia and myalgia Chinese medicine preparation, and its material composition take parts by weight as Herba Lycopodii 40-60 part, Root of Beautiful Millettia 30-40 part, root or all-grass of Umbellateleaf Loosestrife 20-30 part, Root of Philippine Flemingia 30-40 part, Heiguteng exract 20-30 part, Radix Zanthoxyli Spinifolii 20-30 part, white wine or alcohol 400-600 part.
Described material composition take parts by weight as Herba Lycopodii 50 parts, Root of Beautiful Millettia 35 parts, root or all-grass of Umbellateleaf Loosestrife 25 parts, Root of Philippine Flemingia 35 parts, Heiguteng exract 25 parts, Radix Zanthoxyli Spinifolii 25 parts, white wine or alcohol 500 parts.
Described Herba Lycopodii is the stem of Herba Lycopodii; And/or described Root of Beautiful Millettia is Root of Beautiful Millettia root; And/or described root or all-grass of Umbellateleaf Loosestrife is that root or all-grass of Umbellateleaf Loosestrife is entirely careless; And/or described Root of Philippine Flemingia is very heavy uprooting; And/or described Heiguteng exract is Heiguteng exract stem leaf; And/or described Radix Zanthoxyli Spinifolii is Radix Zanthoxyli Spinifolii root skin; And/or the one in described alcohol to be edible ethanol or described white wine be Kaoliang spirit, corn wine, big rice wine.
Described alcohol is 52 �� or described white wine is 52 ��.
Described preparation is the one in capsule, tablet, tincture.
The present invention also provides the preparation method for the treatment of rheumatism arthralgia and myalgia Chinese medicine preparation, comprises the following steps:
(1) Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii cut respectively carefully, pulverize, sieve, then mixed, obtain medicinal powder;
(2), by a kind of meromict in medicinal powder and white wine or alcohol, under room temperature environment, dynamic soaking 5-7 days, completes first time immersion, filters; Obtain first-time filtrate and a filter residue; Being mixed with the one in remaining white wine or alcohol by a filter residue, under room temperature environment, dynamic soaking 5-7 days, completes second time and soaks, filter; Obtain two filtrates and two filter residues;
(3) first-time filtrate being mixed with two filtrates, concentrating under reduced pressure becomes medicinal extract, then its vacuum concentration is dried to powder;
(4) adding pharmaceutics auxiliary material, make the capsule that content of dispersion is 2-4mg, be distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, and to make the tablet that content of dispersion is 2-4mg, it is distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, being mixed with content of dispersion is the tincture of 5-10% in mass, is distributed into bottle, and sealing preserves.
Described dynamic soaking is in immersion process, adopts the immersion device of stand-by whipping appts to soak, and ceaselessly carries out stir process; In whipping process so that the Chinese medicinal materials soaked in device rotates.
Described dynamic soaking, the time every time soaked is 6 days.
Described sieves, and is 80 object sieves.
The Herba Lycopodii adopted or Herba Lycopodii stem, it is in the treatment being used as the diseases such as rheumatism bone pain, muscle network contraction, fracture, wound among the people, and is recorded in " osmanthus medicine volume " and " Guizhou medicinal herbs among the people "; Root of Beautiful Millettia or Root of Beautiful Millettia root are mainly used to treatment lumbar muscle strain, rheumatic arthritis, control lung heat, cough due to deficiency of the lung, pulmonary tuberculosis, chronic bronchitis, chronic hepatitis, seminal emission, the illness such as leukorrhea, be recorded in " whole nation herbal medicine compilation " and " Guizhou medicinal herbs among the people "; Root or all-grass of Umbellateleaf Loosestrife, has the effect dispelled rheumatism, regulate the flow of vital energy and fall apart and tremble with fear, is used for the treatment of the illnesss such as rheumatic arthralgia, hemiplegia, wound, infantile convulsion, is recorded in " Guizhou herbal medicine ", " Guizhou side among the people medicine collection " and " Guizhou medicinal herbs among the people "; Root of Philippine Flemingia or very heavy leatherware of uprooting have expelling wind and removing dampness, the stasis of blood that disappears detoxicating functions, it is used for the treatment of that rheumatic arthralgia, chronic nephritis, wound, carbuncle be swollen and the disease such as tonsillitis, it is recorded in " south of the Five Ridges gather medicinal herbs record ", " Nanning City's medicine will " and " Guizhou medicinal herbs among the people "; Heiguteng exract or Heiguteng exract stem leaf, there is the meridian dredging, drive rheumatism, invigorate blood circulation, anti-inflammatory effect, it is used for the treatment of the diseases such as wound, rheumatism joint pain, menoxenia, stomatitis, mazoitis, it is recorded in " Yunnan herbal medicine ", " Guizhou medicinal herbs among the people " and " Guizhou side's medicine collection among the people "; Radix Zanthoxyli Spinifolii or Radix Zanthoxyli Spinifolii root skin, have expelling wind and cold, activate blood and relax tendons, analgesic efficacy, is usually used in the diseases such as treatment rheumatism numbness, wound, traumatic hemorrhage, cough due to wind and cold, constipation, is recorded in " Guizhou herbal medicine " and " Shaanxi herbal medicine ".
In addition, in this research, after Chinese medicine powder is broken into powder, in the process that it is mixed with white wine or alcohol, it is possible to according to volume ratio be 1: 8-12 mixing after dynamic soaking process.
Preparation prepared by the present invention can comprise and the traditional Chinese medicinal material raw materials proportioning of the present invention being added after pharmaceutics auxiliary material, be prepared into can external application and various preparation types for oral administration, such as capsule for oral administration, tablet, tincture; The spray agent of external application, tincture etc.
The preparation of the present invention is after carrying out endo-medicine, its have first dispel rheumatism, loose cold, stimulate the circulation of the blood and cause the muscles and joints to relax again, the process of anti-inflammatory analgesic, dispel rheumatism, loose cold process mainly cause the distortion of limbs to get rid of raw poison in patient's body, then these raw poison got rid of after in bodies, it will start to stimulate the circulation of the blood and cause the muscles and joints to relax, the function of anti-inflammatory analgesic, and then reach patient is cured completely.
The preparation of the present invention, when carrying out oral, is according to every day three times, is divided into the morning, noon and afternoon each once, and capsule and tablet are each serving with 3-5 grain or sheet; Tincture is each 5-10mL; The time taken is 2h (medicine) being taken before meals use ante cibum.
When adopting the spray agent of the present invention, tincture to carry out external application, it is applied to the position in pain by outside this spray agent, tincture, and rub gently with palm and make it generate heat by painful area, every day Bao Sanci, lasting 7-15 days;
The present invention is adopting when white wine, and it is a kind of better than adopting the effect of 52 �� of big rice wine that it adopts in the Kaoliang spirit of 52 �� and corn wine, and the consumption of white wine be medicinal material total mass 8-12 doubly.
The medicine of the present invention is in the therapeutic process carrying out the illnesss such as rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, and employing is for oral administration with external application and with when treating, it is possible to promotes that the illness of patient obtains comparatively fast treating recovery from illness, alleviates the misery of patient.
Concrete, this investigator also proves the technique effect of the present invention through a large amount of clinical experiments:
By adopting the preparation of the present invention 64 example nongenetic rheumatism, rheumatoid patient to be treated, the effect of its treatment is remarkable, and curative ratio reaches 90%, and 42 example heredity rheumatism, rheumatoid patient is treated, the effect of its treatment is also comparatively remarkable, and curative ratio reaches 60%; Simultaneously also for 64 example nongenetic rheumatism, rheumatoid patient (or 42 example heredity rheumatism, rheumatoid patient), by patient being carried out the contrast experiment of for oral administration and/or external application, its result shows, for oral administration and the external application that adopts and result for the treatment of be significantly better than the effect of single for oral administration and external application for curing, accelerate the recovery from illness speed of rheumatism, rheumatoid patient; Make patient in two weeks just can activity freely, alleviate the misery of patient; Meanwhile, 87 example sacroiliitis, arthralgia and myalgia patient are also treated by this investigator by the preparation of the present invention, and in 2 weeks, sacroiliitis, the arthralgia and myalgia of 87 example patients are all cured, and reach the curative ratio of 100%; In addition, the present invention also adopts said preparation the patient of 62 example wounies, soft tissue injury to be treated, and it reached recovery from illness in 1 week, and its curative ratio is 100%.
The preparation of the treatment rheumatism of the present invention, similar rheumatism, sacroiliitis and arthralgia and myalgia, it is possible to for patients such as each similar rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia so that patient to be reached the effect cured completely; But also the patient of wound, soft tissue injury disease can be acted on, its good effect, there is efficiency to be 100%, and in medication therapeutic process, there is the effect of after treatment, can not recur.
Embodiment
Below in conjunction with concrete enforcement mode, the technical scheme of the present invention is done further restriction, but the description that claimed scope not only is confined to do.
Embodiment 1
One treats rheumatism arthralgia and myalgia Chinese medicine preparation, and the material composition of said preparation is Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii; And after above-mentioned raw materials is mixed, add the one in white wine or alcohol and carry out dynamic soak at room temperature and become. Described Herba Lycopodii is the stem of Herba Lycopodii; And/or described Root of Beautiful Millettia is Root of Beautiful Millettia root; And/or described root or all-grass of Umbellateleaf Loosestrife is that root or all-grass of Umbellateleaf Loosestrife is entirely careless; And/or described Root of Philippine Flemingia is very heavy uprooting; And/or described Heiguteng exract is Heiguteng exract stem leaf; And/or described Radix Zanthoxyli Spinifolii is Radix Zanthoxyli Spinifolii root skin; And/or the one in described alcohol to be edible ethanol or described white wine be Kaoliang spirit, corn wine, big rice wine. Described alcohol is 52 �� or described white wine is 52 ��. Described preparation is the one in capsule, tablet, tincture.
Specifically carrying out above-mentioned treatment rheumatism arthralgia and myalgia Chinese medicine preparation preparation process comprises the following steps:
(1) Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii cut respectively carefully, pulverize, sieve, then mixed, obtain medicinal powder;
(2), by a kind of meromict in medicinal powder and white wine or alcohol, under room temperature environment, dynamic soaking 5-7 days, completes first time immersion, filters; Obtain first-time filtrate and a filter residue; Being mixed with the one in remaining white wine or alcohol by a filter residue, under room temperature environment, dynamic soaking 5-7 days, completes second time and soaks, filter; Obtain two filtrates and two filter residues;
(3) first-time filtrate being mixed with two filtrates, concentrating under reduced pressure becomes medicinal extract, then its vacuum concentration is dried to powder;
(4) adding pharmaceutics auxiliary material, make the capsule that content of dispersion is 2-4mg, be distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, and to make the tablet that content of dispersion is 2-4mg, it is distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, being mixed with content of dispersion is the tincture of 5-10% in mass, is distributed into bottle, and sealing preserves.
It is specifically in immersion process at dynamic soaking described above, adopts the immersion device of stand-by whipping appts to soak, and ceaselessly carry out stir process; In whipping process so that the Chinese medicinal materials soaked in device rotates.
Embodiment 2
On the basis of embodiment 1, other are all with embodiment 1, one treats rheumatism arthralgia and myalgia Chinese medicine preparation, and its material composition counts Herba Lycopodii 40kg, Root of Beautiful Millettia 30kg, root or all-grass of Umbellateleaf Loosestrife 20kg, Root of Philippine Flemingia 30kg, Heiguteng exract 20kg, Radix Zanthoxyli Spinifolii 20kg, white wine or alcohol 400kg with weight.
Described dynamic soaking, the time every time soaked is 6 days.
Embodiment 3
On the basis of embodiment 1, other are all with embodiment 1, one treats rheumatism arthralgia and myalgia Chinese medicine preparation, and its material composition counts Herba Lycopodii 60kg, Root of Beautiful Millettia 40kg, root or all-grass of Umbellateleaf Loosestrife 30kg, Root of Philippine Flemingia 40kg, Heiguteng exract 30kg, Radix Zanthoxyli Spinifolii 30kg, white wine or alcohol 600kg with weight.
Described sieves, and is 80 object sieves.
Embodiment 4
On the basis of embodiment 1, other are all with embodiment 1, and described material composition counts Herba Lycopodii 50kg, Root of Beautiful Millettia 35kg, root or all-grass of Umbellateleaf Loosestrife 25kg, Root of Philippine Flemingia 35kg, Heiguteng exract 25kg, Radix Zanthoxyli Spinifolii 25kg, white wine or alcohol 500kg with weight.
In addition, the present invention also provides the following embodiment scheme specifically carrying out operating in pilot product production process:
Embodiment 5
Treat a capsule for rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, Herba Lycopodii stem 2.0kg, Root of Beautiful Millettia 1.5kg, root or all-grass of Umbellateleaf Loosestrife 1.0kg, Root of Philippine Flemingia 1.0kg, Heiguteng exract 1.0kg, Radix Zanthoxyli Spinifolii 0.5kg; Its preparation method be traditional Chinese medicinal material raw materials is cut respectively thin, pulverize, process of sieving is to 80 orders, medicinal powder is obtained after mixing, get 70kg white wine again, after it is mixed with medicinal powder, soak 6 days, in immersion process, it takes continuous stir process, make medicinal powder be suspended in white wine, then filter, obtain first-time filtrate and a filter residue; Mix immersion 6 days with 70kg white wine with a filter residue again, and constantly stir in immersion process so that one time filter residue is suspended in white wine, then after its filtration, will obtain two filtrates and two filter residues; After first-time filtrate and two filtrates being mixed, concentrating under reduced pressure becomes medicinal extract, then purifying vacuum concentration further for medicinal extract is dried to powder, add corresponding pharmaceutics auxiliary material stearic acid again, it is prepared into the capsule that content of dispersion is 2mg, is then distributed into bottle, sealing preserves, and namely makes 500 bottles, 50 every bottle.
Embodiment 6
Treating a tablet for rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, on the basis of embodiment 5, other are all with embodiment 5, Herba Lycopodii stem 2.0kg, Root of Beautiful Millettia 1.5kg, root or all-grass of Umbellateleaf Loosestrife 1.0kg, Root of Philippine Flemingia 1.0kg, Heiguteng exract 1.0kg, Radix Zanthoxyli Spinifolii 0.5kg; White wine 80kg; Soaking at normal temperatures, one time soak time is 5 days, and two times soak time is 7 days, and after the filtrate once soaked and two times are soaked is mixed, concentrating under reduced pressure becomes medicinal extract, then after medicinal extract purifying vacuum concentration is dried to powder, at the corresponding pharmaceutics auxiliary material of interpolation, such as lactose, being prepared into the tablet that content of dispersion is 2mg, be then distributed into bottle, sealing preserves, namely 500 bottles are made, 50 every bottle.
Embodiment 7
Treating a tincture for rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, on the basis of embodiment 5, other are all with embodiment 5, Herba Lycopodii stem 2.0kg, Root of Beautiful Millettia 1.5kg, root or all-grass of Umbellateleaf Loosestrife 1.0kg, Root of Philippine Flemingia 1.0kg, Heiguteng exract 1.0kg, Radix Zanthoxyli Spinifolii 0.5kg; White wine 75kg; Soaking at normal temperatures, one time soak time is 7 days, and two times soak time is 5 days, and after the filtrate once soaked and two times are soaked is mixed, concentrating under reduced pressure becomes medicinal extract, then after medicinal extract purifying vacuum concentration is dried to powder, at the corresponding pharmaceutics auxiliary material of interpolation, such as glucose syrup, being prepared into the tincture that content of dispersion is 5%, be then distributed into bottle, sealing preserves, namely 500 bottles are made, every bottle of 100ml.
Embodiment 8
Treat an externally applied formulation for rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, adopt Herba Lycopodii stem 2.0kg, Root of Beautiful Millettia 1.5kg, root or all-grass of Umbellateleaf Loosestrife 1.0kg, Root of Philippine Flemingia 1.0kg, Heiguteng exract 1.0kg, Radix Zanthoxyli Spinifolii 0.5kg; The alcohol of 80kg, after traditional Chinese medicinal material raw materials respectively grind into powder, it is mixed with alcohol immersion, and in immersion process, it is carried out constant stir process, Chinese medicinal materials is suspended in spirituous solution, after soak time reaches 12 days, filtered, and filtrate is condensed into medicinal extract, again by medicinal extract vacuum concentration to being dried to powder, being added pharmaceutics auxiliary material again and be prepared into the tincture that content of dispersion is 10%, be then distributed into bottle, sealing preserves, bottling into 300 bottles, every bottle is 100ml.
Embodiment 9
On the basis of embodiment 1, other are all with embodiment 1, and it is when being prepared into capsule, adopt Herba Lycopodii stem 2.0kg, Root of Beautiful Millettia 1.5kg, root or all-grass of Umbellateleaf Loosestrife 1.0kg, Root of Philippine Flemingia 1.0kg, Heiguteng exract 1.0kg, Radix Zanthoxyli Spinifolii 0.5kg; The white wine of 85kg, is prepared into capsule, and content of dispersion is 4mg, is prepared into 300 bottles, 50 every bottle.
The above embodiments are not that limit is in the explanation of the operation scheme of the present invention, but the brief operation of the technical scheme of the present invention is made the description and interpretation of guided bone, it it is not the further restriction of the technical scheme to the present invention, embodiments of the invention are except above-mentioned introduction, its in certain embodiments, its white wine adopted is be one in Kaoliang spirit, corn wine, big rice wine; In certain embodiments, its white wine adopted is 52 ��; Meanwhile, its alcohol adopted in certain embodiments is the one in edible ethanol, medicinal alcohol; The alcoholic strength of alcohol in certain embodiments is 52 ��.
In addition, in certain embodiments, its Chinese medicinal materials adopted language set forth on array mode be several as follows: the stem of Herba Lycopodii or Herba Lycopodii; And/or Root of Beautiful Millettia or Root of Beautiful Millettia root; And/or root or all-grass of Umbellateleaf Loosestrife or root or all-grass of Umbellateleaf Loosestrife entirely careless; And/or Root of Philippine Flemingia or very heavy skin of uprooting; And/or Heiguteng exract or Heiguteng exract stem leaf; And/or Radix Zanthoxyli Spinifolii or Radix Zanthoxyli Spinifolii root skin; That is, above-mentioned traditional Chinese medicinal material raw materials is when combining, and when being really difficult to the traditional Chinese medicinal material raw materials finding embodiment 1-3, it can also adopt other positions of this Chinese medicinal materials to replace, and it also can realize effect.
In other embodiment, when it is a kind of in Kaoliang spirit or corn wine for the white wine adopted, its pharmacological effect produced is more remarkable.
In addition, in certain embodiments, it is not the one being prepared in capsule, tablet, tincture, and it is any one dosage form being prepared in pharmacy preparation so that treatment rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia are conveniently carried out treatment and use by it. As prepared spray agent, put agent on the skin, aromatic water, solution, injection, mixture, lotion, powder, pill, film agent, ointment, paste, gelifying agent, air pressure agent etc.
When the auxiliary material of the pharmaceutics adopted in the present invention is not clearly explained in certain embodiments, what it adopted is be prepared into this kind of preparation, one or several in pharmaceutics auxiliary material conventional inside pharmaceutics mix and add, and after adding pharmaceutics auxiliary material, its preparation that can meet preparation meets the following conditions: during the shape such as solid particulate, tablet, and the medicine content met in every sheet or every is 2-4mg; During for liquid preparation, it to be met content of dispersion in mass for 5-10% is better.
The preparation of the treatment rheumatism of the present invention, similar rheumatism, sacroiliitis and arthralgia and myalgia, a kind of effective, safe, quick-acting pharmaceutical preparation, can the clinical patient for all kinds for the treatment of rheumatism, similar rheumatism, sacroiliitis and arthralgia and myalgia, good effect, efficacy consolidation after curing, does not recur.
Claims (10)
1. a treatment rheumatism arthralgia and myalgia Chinese medicine preparation, it is characterised in that, the material composition of said preparation is Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii; And after above-mentioned raw materials is mixed, add the one in white wine or alcohol and carry out dynamic soak at room temperature and become.
2. a treatment rheumatism arthralgia and myalgia Chinese medicine preparation, it is characterized in that, its material composition take parts by weight as Herba Lycopodii 40-60 part, Root of Beautiful Millettia 30-40 part, root or all-grass of Umbellateleaf Loosestrife 20-30 part, Root of Philippine Flemingia 30-40 part, Heiguteng exract 20-30 part, Radix Zanthoxyli Spinifolii 20-30 part, white wine or alcohol 400-600 part.
3. treatment rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 1 or 2, it is characterized in that, described material composition take parts by weight as Herba Lycopodii 50 parts, Root of Beautiful Millettia 35 parts, root or all-grass of Umbellateleaf Loosestrife 25 parts, Root of Philippine Flemingia 35 parts, Heiguteng exract 25 parts, Radix Zanthoxyli Spinifolii 25 parts, white wine or alcohol 500 parts.
4. treatment rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 1 or 2, it is characterised in that, described Herba Lycopodii is the stem of Herba Lycopodii; And/or described Root of Beautiful Millettia is Root of Beautiful Millettia root; And/or described root or all-grass of Umbellateleaf Loosestrife is that root or all-grass of Umbellateleaf Loosestrife is entirely careless; And/or described Root of Philippine Flemingia is very heavy uprooting; And/or described Heiguteng exract is Heiguteng exract stem leaf; And/or described Radix Zanthoxyli Spinifolii is Radix Zanthoxyli Spinifolii root skin; And/or the one in described alcohol to be edible ethanol or described white wine be Kaoliang spirit, corn wine, big rice wine.
5. treatment rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 1 or 2, it is characterised in that, described alcohol is 52 �� or described white wine is 52 ��.
6. treatment rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 1 or 2, it is characterised in that, described preparation is the one in capsule, tablet, tincture.
7. the preparation method for the treatment of rheumatism arthralgia and myalgia Chinese medicine preparation as described in item as arbitrary in claim 1-6, it is characterised in that, comprise the following steps:
(1) Herba Lycopodii, Root of Beautiful Millettia, root or all-grass of Umbellateleaf Loosestrife, Root of Philippine Flemingia, Heiguteng exract, Radix Zanthoxyli Spinifolii cut respectively carefully, pulverize, sieve, then mixed, obtain medicinal powder;
(2), by a kind of meromict in medicinal powder and white wine or alcohol, under room temperature environment, dynamic soaking 5-7 days, completes first time immersion, filters; Obtain first-time filtrate and a filter residue; Being mixed with the one in remaining white wine or alcohol by a filter residue, under room temperature environment, dynamic soaking 5-7 days, completes second time and soaks, filter; Obtain two filtrates and two filter residues;
(3) first-time filtrate being mixed with two filtrates, concentrating under reduced pressure becomes medicinal extract, then its vacuum concentration is dried to powder;
(4) adding pharmaceutics auxiliary material, make the capsule that content of dispersion is 2-4mg, be distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, and to make the tablet that content of dispersion is 2-4mg, it is distributed into bottle, sealing preserves; Or add pharmaceutics auxiliary material, being mixed with content of dispersion is the tincture of 5-10% in mass, is distributed into bottle, and sealing preserves.
8. the preparation method for the treatment of rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 7, it is characterised in that, described dynamic soaking is in immersion process, adopts the immersion device of stand-by whipping appts to soak, and ceaselessly carries out stir process; In whipping process so that the Chinese medicinal materials soaked in device rotates.
9. the preparation method for the treatment of rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 7, it is characterised in that, described dynamic soaking, the time every time soaked is 6 days.
10. the preparation method for the treatment of rheumatism arthralgia and myalgia Chinese medicine preparation as claimed in claim 7, it is characterised in that, described sieves, and is 80 object sieves.
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| CN108354955A (en) * | 2018-05-24 | 2018-08-03 | 贵阳中医学院 | Application of the starflowerlike loosestrife root or herb in preparing the drug for repairing joint injury |
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Application publication date: 20160601 |