CN105616216A - Natural whitening skin care product composition - Google Patents

Abstract

The invention discloses a natural whitening skin care product composition, which is prepared from the following raw materials in parts by weight: 1-7 parts of a grape seed extract, 1-8 parts of a bletilla striata extract, 1-6 parts of a tropaeolum majus extract, 1-10 parts of an aloe extract, 1-8 parts of a liquorice extract, 1-9 parts of a kudzu root extract, 1-5 parts of a rhizoma typhonii extract, 1-7 parts of a linden flower extract, 1-8 parts of an extract from phyllanthus emblica L. fruit, 0.5-5 parts of a black pepper extract, 1-6 parts of a common perilla extract, 1-9 parts of a white willow extract and 0.5-6 parts of a radix sophorae flavescentis extract. The skin care product composition disclosed by the invention, on the basis of comprehensive consideration of various reasons causing melanin as well as function and compatibility of each raw material, is prepared by scientifically matching the extracts of 14 well selected natural plants.

Description

Natural whiting composite skin care product

Technical field

The present invention relates to biological skin care industry, be specially a kind of natural whiting composite skin care product.

Background technology

Whitening skin is all that people seeking beauty constantly pursues all the time. Affect a lot of because have of whitening, the ubiquitous electromagnetic radiation of dietary habit depressed, unsound as excessive in mental pressure, long-term, modern society, the cosmetics that excessive use zest is strong, endocrine disturbance, air pollution etc., but the deterrent that skin-whitening is maximum is also originated from UV ultraviolet. UV ultraviolet causes Mai Laning melanin to increase, and this is the main cause causing skin darkening. In our human body, everyone melanocyte is quantitatively essentially identical, why can black and white different, its main cause is the difference of melanin quantity. Melanin among melanocyte, itself is a kind of protein by " manufactures ", and it is via generation after tryrosinase effect, along with the natural renovation of cell, melanin by gradually shift horny layer onto, just can become the black splotch that we have seen that. Therefore, how to suppress the effect of tryrosinase to alleviate the key that melanic generation is whitening.

Nowadays conventional on the market whitening agent mainly has Benzodiazepines, kojic acid, glutathion, arbutin, cysteine, ascorbic acid etc., there is no small zest and safety problem, the cosmetics that life-time service is made up of these whitening agents, likely can cause the untoward reaction such as red swelling of the skin pruritus, allergy, decortication, not only result in the weak of the shining new ability of skin self but also have impact on health more or less. Therefore, need badly and produce a kind of safely and effectively non-stimulated natural whiting composite skin care product.

Here the plant extract that natural skin care product compositions refers in plant component contained in its compositions have to obtain Organic certification, in addition must also can not adding artificial flavors, pigment and petroleum chemicals etc. to the disadvantageous composition of skin in product, the preservative solvent etc. wherein added also has been affected by extremely strictly limiting.

Summary of the invention

It is an object of the invention to provide a kind of to skin-whitening safely and effectively, can life-time service no dependence, it is possible to for the compositions of the natural whiting skin care item of sensitivity skin.

Natural whiting composite skin care product of the present invention is made up of the raw material of following parts by weight: OPC 1��7 part, Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1��8 part, nasturtium extract 1��6 part, aloe extract 1��10 part, Radix Glycyrrhizae extract 1��8 part, Radix Puerariae extract 1��9 part, Rhizoma Typhonii extract 1��5 part, Flos tiliae miquelianae extract 1��7 part, Fructus Phyllanthi fruit extract 1��8 part, black pepper extract 0.5��5 part, Perilla frutescens extract 1��6 part, Salix alba leaf extract 1��9 part and Radix Sophorae Flavescentis extract 0.5��6 part.

The present invention is on the basis of a variety of causes and each raw material effect and the compatibility that consider melanin formation, selected 14 kinds of natural plant extracts also form through scientific matching, concrete effect includes: (1) Radix Puerariae extract, Semen Vitis viniferae extract etc., and skin-whitening is had obvious action; (2) Fructus piperis nigrum extract, Extracts from Perilla frutescens etc., it is possible to effectively alleviate the melanic formation because ultraviolet causes; (3) Aloe extract etc., it is possible to alleviate scytitis well, and then avoid causing melanic formation because of chafing; (4) paeonol is as a kind of tyrosinase inhibitor, and the mitigation that melanin is formed is just particularly evident, and it can either directly through the activity of suppression TYR enzyme and then blocking-up or alleviate melanic formation. Raw material in above-mentioned each component cooperates, mutually coordinated, tyrosinase activity can be suppressed fully and effectively, reduce melanin and formed, serve significant whitening effect.

Detailed description of the invention

Enumerate several concrete example below to be verified. It should be noted that, make natural plants cosmetic composition weight proportion of the present invention, be not limited in the weight portion in following instance, but through experiment, after exceeding the upper limit of said ratio scope, the effect that whitening effect increases can't be further continued for obvious enhancing.

The component of the natural plants cosmetic composition used in example 1��3 and weight proportion such as following table thereof:

This product preparation method is as follows: each component is pressed proportion speed and weighs, be sufficiently mixed and stir. What the refinement method of the plant extract comprised mainly adopted is macroporous resin extraction method. , Amberlyst process is by adopting special adsorbent to adsorb effective ingredient therein from above-mentioned plant material solution selectively, and removes a kind of extracting method of invalid components. It has the advantages such as adsorptive selectivity, simple to operate, regeneration is convenient, desorption condition is gentle, safe and reliable. The concrete operating procedure of Amberlyst process is as follows: the first step, plant to be extracted washed, dry, pulverizing standby. Second step, gets out extract associated materials during operation. These materials include: standby plant powder, macroporous adsorbent resin, ethanol, hydrochloric acid, PH meter, Rotary Evaporators, centrifuge, pipettor, pipet, volumetric flask in step one, be heated to reflux device baking oven, chromatographic column, beaker, filter paper, 60 mesh sieves. 3rd step, proportionally weighs united extraction liquid after then plant material fine powder decocts with water heating respectively respectively. Extracting solution is cooled to after room temperature respectively and regulates to pH value suitable accordingly with hydrochloric acid respectively, and is filled with after carrying out centrifugal filtration. 4th step, is quantitatively drawn the centrifugal liquid of respective volume respectively, is adsorbed by macroporous adsorptive resins, with water rinse resin post to clarification after absorption, more thin to eluent color with certain density alcohol flushing post bed. Use certain density ethanol elution, then collect this elution fractions.

The Inhibition test of tryrosinase is made of the plant extract weight proportion in above-described embodiment 1��3:

The path that the melanin generally acknowledged at present is formed is: tyrosine is as melanic primary raw material, catalysis by tryrosinase, TYR is made to be converted into DOPA, and catalysis DOPA is converted into DOPA quinone, and then it is converted into dopachrome, it is then converted to dihydroxy indole, keto-acid indole, is eventually converted into melanocyte. The activity suppressing tryrosinase is the key stoping or alleviating melanin to be formed.

The content measuring DOPA quinone can draw the use present invention inhibitory action to TYR enzyme, and the content of DOPA quinone can pass through ultraviolet spectrometer (475) and measure. During mensuration, reaction carries out in test tube, by uniform for the sample mix of the present invention that the levodopa of 1mL30mmol/L, phosphate buffer and concentration are 0.1mg/ml, it is positioned in the water-bath of 26 degrees Celsius again and reacts 15 minutes, it is subsequently added tyrosinase solution, making total reaction volume is 10mL, it is incubated 15 minutes then at 26 degrees Celsius, finally measures OD value in 721 spectrophotometer 475nm places, and carry out the comparison of sample cell OD value and control tube OD value. Calculate the suppression ratio of tryrosinase vigor. Computing formula is: suppression ratio=(after suppressing protyrosinase gross activity-plant extract to suppress residue tyrosinase activity)/suppress protyrosinase gross activity, by calculating: after the plant extract mixed solution preparation of the present invention that working concentration is 0.1mg/ml, the plant extract mixed liquor preparation of the present invention to the maximal percentage inhibition of tryrosinase up to 55.8%.

Claims (1)

1. a natural whiting composite skin care product, it is characterised in that it is made up of the raw material of following parts by weight: OPC 1��7 part, Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1��8 part, nasturtium extract 1��6 part, aloe extract 1��10 part, Radix Glycyrrhizae extract 1��8 part, Radix Puerariae extract 1��9 part, Rhizoma Typhonii extract 1��5 part, Flos tiliae miquelianae extract 1��7 part, Fructus Phyllanthi fruit extract 1��8 part, black pepper extract 0.5��5 part, Perilla frutescens extract 1��6 part, Salix alba leaf extract 1��9 part and Radix Sophorae Flavescentis extract 0.5��6 part.