CN105614764A - Preparation method of mulberry nanometer microcapsule and nutrition powder prepared from mulberry nanometer microcapsule - Google Patents
Preparation method of mulberry nanometer microcapsule and nutrition powder prepared from mulberry nanometer microcapsule Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation method of a mulberry nanometer microcapsule. The method includes the steps of extracting raw material mulberries with ethanol water with the aid of ultrasonic waves, wherein the volume percent of the ethanol water is 45-50%; separating the obtained extracting solution through a three-level membrane to obtain purified concentrated liquor; dropwise adding the purified concentrated liquor to a preheated nanometer carrier solution, wherein pH of the nanometer carrier solution is 6.5-6.9; conducting embedding under vortex oscillation at a temperature of 20-25 DEG C to obtain an embedding solution; conducting spray freeze drying on the embedding solution to obtain the mulberry nanometer microcapsule. Nutrition powder is prepared from 3-8 parts of mulberry nanometer microcapsule, 24-32 parts of mulberry fruit powder, 12-16 parts of fructus lycii powder, 8-12 parts of purple sweet potato powder, 12-16 parts of carrot powder, 5-10 parts of walnut kernel powder, 20-30 parts of soybean meal, 20-30 parts of wheat germ meal and 16-20 parts of corn gluten meal. The anthocyanin content of the mulberry nanometer microcapsule prepared from the nanometer microcapsule through the combination with the spray freeze drying process reaches up to 200-300 mg/g, and the grain size of the spray freeze drying can be stably kept at 20-100 nm, and therefore it is ensured that the anthocyanin absorption rate is high.
Description
Technical field
The present invention relates to food processing technology field, in particular to a kind of mulberry fruit capsule of nano preparation method and consisting of nutritive powder.
Background technology
Anthocyanidin, also known as cyanidin(e), is a class natural pigment, belongs to flavonoids, is extensively present in the vegetable and fruit of all scarlets, purple or blueness, in the such as tissue of mulberry fruit, grape, blueberry, purple potato, black (red) plant such as rice, black soya bean.
Research proves that anthocyanidin is that mankind nowadays finds most good antioxidant, have anti-ageing, anti-mutation, prevention of arterial are atherosis, protect liver, protect the effects such as eye. Anthocyanidin in clinical medicine report display blueberry can promote the regeneration of rhodopsin in retina cell, can prevent laser high myopia and detachment of retina, and can promote eyesight. Cyanidin(e) can improve the eyesight under dim light; This is for motorist at night, and people watching screen for a long time attentively etc. is helpful. Anthocyanidin is potent antioxidant, can maintain the flowing stablizing, promoting fine vascular circulation, raising capillary blood vessel and vein of normal cell linkages, blood vessel, can effectively suppress to destroy the enzymic activity of eye cell, thus be of value to the health of eyes.
The biological effectiveness of human body is 100% by anthocyanidin, takes and just can detect in blood for latter 20 minutes. But anthocyanidin also exists some defects, as anthocyanidin is very responsive to pH value, temperature, illumination, metal ion, stability is poor. But extract in tradition, degraded that evaporation concentration common in concentrated, purifying process, pH value change all easily cause cyanidin(e). In some plants; the hydrolysis that a small amount of acid can make the anthocyanogen of acylations part or all of; the multiple method extracting anthocyanidin from grape being compared test proof, the anthocyanogen partial hydrolysis of acylations just can be made when the HCl in solvent reaches 0.12mol/L.
In addition, adopting existing general preparation method to prepare Fructus Mori extract, the anthocyanidin content obtained is about about 100mg/g, extracts the anthocyanidin content that obtains low, does not have and good protects an eyesight-improving health care function function.
In recent years, capsule of nano technology has become a focus of food research and Application Areas. Use capsule of nano technology to be embedded by activeconstituents, both can reduce the loss of activeconstituents in processing, storage, can effectively activeconstituents be transported in human body again. The specific targeting of Nano capsule can make functional factor change distribution and concentrate in specific target tissue, the object reduce toxicity to reach, improving curative effect, and improve its bioavailability by Co ntrolled release functional factor, keep the quality of food, structure and its sensory appeal simultaneously.
Summary of the invention
In order to overcome the deficiencies in the prior art or defect, it is an object of the invention to provide the preparation method of a kind of mulberry fruit capsule of nano, adopt anthocyanidin content height and the anthocyanidin specific absorption height of the mulberry fruit capsule of nano that this preparation method obtains.
It is a further object of the present invention to provide the nutritive powder comprising above-mentioned mulberry fruit capsule of nano.
The present invention realizes the object of the present invention by the following technical solutions:
A preparation method for mulberry fruit capsule of nano, comprises the following steps:
Volume percent is adopted to be the aqueous ethanolic solution of 45-50% raw material mulberry fruit, and it is aided with ultrasonic extraction, the extracting solution obtained is through three grades of membrane sepn, obtain purifying concentrated solution, the concentrated drop of purifying enters in the nano-carrier solution that the heat treatment in advance that pH is 6.5-6.9 is crossed, at temperature is 20-25 DEG C, vortex oscillation embeds, and obtains encapsulating solution, and this encapsulating solution is through the obtained mulberry fruit capsule of nano of freezing spraying dry.
Wherein, the anthocyanidin content of described mulberry fruit capsule of nano is 200-300mg/g.
Wherein, the nanoparticle particle diameter of described mulberry fruit capsule of nano is 20-100nm.
Wherein, the feed liquid mass volume ratio of described raw material mulberry fruit and aqueous ethanolic solution is 1:10-25; The processing condition of described ultrasonic extraction are: ultrasonic power is 410-450W, and ultrasonic frequency is 40-50KHz, and ultrasonic treatment time is 5-9min.
Wherein, the film of described three grades of membrane sepn is selected from the combination of ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three kinds of films, and it is 2000-2500mg/L that membrane sepn obtains the concentrated concentration of purifying concentrated solution.
Wherein, the carrier in the nano-carrier solution of described heat treatment in advance be selected from beta-lactoglobulin, whey protein concentrate, soybean lecithin, low-methoxy pectin, gelatin, chitosan, glycolipid one or more; Treatment temp 60-70 DEG C of described heat treatment in advance, treatment time 5-20min.
Wherein, described freezing spray-dired processing condition are: feed rate is 31-35ml/min, and freezing spray drying temperature is-40--30 DEG C.
A nutritive powder for the mulberry fruit capsule of nano that the preparation method comprising above-mentioned mulberry fruit capsule of nano obtains, by weight, comprises following component:
Mulberry fruit capsule of nano 3-8 part;
Mulberry fruit fruit powder 24-32 part;
Medlar powder 12-16 part;
Purple sweet potato powder 8-12 part;
Carrot meal 12-16 part;
Walnut kernel powder 5-10 part;
Soyflour 20-30 part;
Wheat germ powder 20-30 part;
Zein powder 16-20 part.
Wherein, described mulberry fruit fruit powder, medlar powder, purple sweet potato powder, carrot meal, walnut kernel powder, soyflour, wheat germ powder, Zein powder are degree of grinding is 100-200 object dried powder.
The present invention compared with prior art, has following useful effect:
1) the present invention adopts the anthocyanidin content of the mulberry fruit capsule of nano that capsule of nano prepares in conjunction with freezing drying process with atomizing up to 200-300mg/g, and can stablize and keep capsule of nano particle diameter to be 20-100nm, thus ensure that anthocyanidin specific absorption is up to 100%.
2) the present invention by above-mentioned mulberry fruit capsule of nano, be aided with mulberry fruit fruit powder, medlar powder, purple sweet potato powder, carrot meal, walnut kernel powder, soyflour, wheat germ powder, Zein powder reasonably combined, can be prepared into have and protect a nutritive powder for eyesight-improving health care function function, can as a long time with the daily meal replacing food of eye crowd, playing the effect alleviating visual fatigue, protection eyesight; And raw material is easy to get, preparation technology is relatively simple, and cost can be controlled.
Embodiment
Below by embodiment, the present invention being described further, following examples are that the present invention preferably implements mode, but embodiments of the present invention are not by the restriction of following embodiment.
Embodiment 1
Adopting 15L volume percent to be the aqueous ethanolic solution of 45wt% 1kg raw material mulberry fruit, and be aided with ultrasonic extraction, wherein ultrasonic power is 430W, and ultrasonic frequency is 45KHz, and ultrasonic treatment time is 7min, the extracting solution obtained is through ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three grades of membrane sepn, obtain the purifying concentrated solution that concentration is 2200mg/L, the concentrated drop of purifying enters the heat treatment in advance (treatment temp of heat treatment in advance 65 DEG C that pH is 6.7, treatment time 10min) cross nanometer beta-lactoglobulin solution in, at temperature is 20-25 DEG C, vortex oscillation embeds, obtain encapsulating solution, this encapsulating solution carries out the mulberry fruit capsule of nano of the obtained microcapsule particle diameter of freezing spraying dry as 60nm taking the feed rate of 33ml/min at-40 DEG C, can ensure that anthocyanidin specific absorption is up to 100%, and anthocyanidin content is up to 250mg/g.
Get the above-mentioned mulberry fruit capsule of nano prepared 5 parts; Mulberry fruit fruit 28 parts, powder; Medlar powder 14 parts; Purple sweet potato powder 9 parts; Carrot meal 13 parts; 7 parts, walnut kernel powder; Soyflour 25 parts; Wheat germ powder 22 parts; Zein powder 18 parts, mix and obtain a kind of have protect a nutritive powder for eyesight-improving health care function function.
According to the nutritional powder formula of embodiment 1,1000 people try out, and wherein 957 people think that the present invention has significant health-care effect in the bright order of eye protecting, and satisfaction rate is up to 95.7%.
Embodiment 2
Adopting 10L volume percent to be the aqueous ethanolic solution of 40wt% 1kg raw material mulberry fruit, and be aided with ultrasonic extraction, wherein ultrasonic power is 410W, and ultrasonic frequency is 40KHz, and ultrasonic treatment time is 9min, the extracting solution obtained is through ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three grades of membrane sepn, obtain the purifying concentrated solution that concentration is 2000mg/L, the concentrated drop of purifying enters the heat treatment in advance (treatment temp of heat treatment in advance 60 DEG C that pH is 6.9, treatment time 20min) cross nanometer whey protein concentrate solution in, at temperature is 20-25 DEG C, vortex oscillation embeds, obtain encapsulating solution, this encapsulating solution carries out the mulberry fruit capsule of nano of the obtained microcapsule particle diameter of freezing spraying dry as 80nm taking the feed rate of 31ml/min at-30 DEG C, can ensure that anthocyanidin specific absorption is up to 99.9%, and anthocyanidin content is up to 230mg/g.
Get the above-mentioned mulberry fruit capsule of nano prepared 3 parts; Mulberry fruit fruit 32 parts, powder; Medlar powder 16 parts; Purple sweet potato powder 12 parts; Carrot meal 16 parts; 10 parts, walnut kernel powder; Soyflour 30 parts; Wheat germ powder 30 parts; Zein powder 20 parts, mix and obtain a kind of have protect a nutritive powder for eyesight-improving health care function function.
According to the nutritional powder formula of embodiment 2,1000 people try out, and wherein 943 people think that the present invention has significant health-care effect in the bright order of eye protecting, and satisfaction rate is up to 94.3%.
Embodiment 3
Adopting 25L volume percent to be the aqueous ethanolic solution of 50wt% 1kg raw material mulberry fruit, and be aided with ultrasonic extraction, wherein ultrasonic power is 450W, and ultrasonic frequency is 50KHz, and ultrasonic treatment time is 5min, the extracting solution obtained is through ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three grades of membrane sepn, obtain the purifying concentrated solution that concentration is 2500mg/L, the concentrated drop of purifying enters the heat treatment in advance (treatment temp of heat treatment in advance 70 DEG C that pH is 6.5, treatment time 5min) cross nanometer soybean lecithin soln in, at temperature is 20-25 DEG C, vortex oscillation embeds, obtain encapsulating solution, this encapsulating solution carries out the mulberry fruit capsule of nano of the obtained diameter of particle of freezing spraying dry as 50nm taking the feed rate of 35ml/min at-35 DEG C, can ensure that anthocyanidin specific absorption is up to 99.8%, and anthocyanidin content is up to 300mg/g.
Get the above-mentioned mulberry fruit capsule of nano prepared 8 parts; Mulberry fruit fruit 24 parts, powder; Medlar powder 12 parts; Purple sweet potato powder 8 parts; Carrot meal 12 parts; 5 parts, walnut kernel powder; Soyflour 20 parts; Wheat germ powder 20 parts; Zein powder 16 parts, mix and obtain a kind of have protect a nutritive powder for eyesight-improving health care function function.
According to the nutritional powder formula of embodiment 3,1000 people try out, and wherein 964 people think that the present invention has significant health-care effect in the bright order of eye protecting, and satisfaction rate is up to 96.4%.
Comparative example 1:
The aqueous ethanolic solution that 1kg raw material mulberry fruit employing 30L volume fraction is 50% is extracted 30min in room temperature, repeat to extract 3 times, the extracting solution obtained is after vacuum concentration, lyophilize, obtain Fructus Mori extract dry powder, the anthocyanidin content of this Fructus Mori extract dry powder is only 87.8mg/g, and anthocyanidin content is lower, and anthocyanidin specific absorption is only 85%.
Comparative example 2:
Adopting 15L volume percent to be the aqueous ethanolic solution of 45wt% 1kg raw material mulberry fruit, and be aided with ultrasonic extraction, wherein ultrasonic power is 430W, and ultrasonic frequency is 45KHz, and ultrasonic treatment time is 7min; The extracting solution obtained is through ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three grades of membrane sepn, obtain the purifying concentrated solution that concentration is 2200mg/L, the concentrated drop of purifying enters the heat treatment in advance (treatment temp of heat treatment in advance 65 DEG C that pH is 6.7, treatment time 10min) cross nanometer beta-lactoglobulin solution in, at temperature is 20-25 DEG C, vortex oscillation embeds, obtain encapsulating solution, the spray-dried obtained microcapsule particle diameter of this encapsulating solution is the mulberry fruit microcapsule of 240nm, this anthocyanidin specific absorption is only 89%, and anthocyanidin content is only 102mg/g.
Claims (9)
1. the preparation method of a mulberry fruit capsule of nano, it is characterised in that, comprise the following steps:
Volume percent is adopted to be the aqueous ethanolic solution of 45-50% raw material mulberry fruit, and it is aided with ultrasonic extraction, the extracting solution obtained is through three grades of membrane sepn, obtain purifying concentrated solution, the concentrated drop of purifying enters in the nano-carrier solution that the heat treatment in advance that pH is 6.5-6.9 is crossed, at temperature is 20-25 DEG C, vortex oscillation embeds, and obtains encapsulating solution, and this encapsulating solution is through the obtained mulberry fruit capsule of nano of freezing spraying dry.
2. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterised in that, the anthocyanidin content of described mulberry fruit capsule of nano is 200-300mg/g.
3. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterised in that, the nanoparticle particle diameter of described mulberry fruit capsule of nano is 20-100nm.
4. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterised in that, the feed liquid mass volume ratio of described raw material mulberry fruit and aqueous ethanolic solution is 1:10-25; The processing condition of described ultrasonic extraction are: ultrasonic power is 410-450W, and ultrasonic frequency is 40-50KHz, and ultrasonic treatment time is 5-9min.
5. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterized in that, the film of described three grades of membrane sepn is selected from the combination of ultra-filtration membrane, nanofiltration membrane, reverse osmosis membrane three kinds of films, and it is 2000-2500mg/L that membrane sepn obtains the concentrated concentration of purifying concentrated solution.
6. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterized in that, the carrier in the nano-carrier solution of described heat treatment in advance be selected from beta-lactoglobulin, whey protein concentrate, soybean lecithin, low-methoxy pectin, gelatin, chitosan, glycolipid one or more; Treatment temp 60-70 DEG C of described heat treatment in advance, treatment time 5-20min.
7. the preparation method of mulberry fruit capsule of nano according to claim 1, it is characterised in that, described freezing spray-dired processing condition are: feed rate is 31-35ml/min, and freezing spray drying temperature is-40--30 DEG C.
8. a nutritive powder for the mulberry fruit capsule of nano that the preparation method comprising the mulberry fruit capsule of nano described in the arbitrary item of claim 1-7 obtains, by weight, comprises following component:
Mulberry fruit capsule of nano 3-8 part;
Mulberry fruit fruit powder 24-32 part;
Medlar powder 12-16 part;
Purple sweet potato powder 8-12 part;
Carrot meal 12-16 part;
Walnut kernel powder 5-10 part;
Soyflour 20-30 part;
Wheat germ powder 20-30 part;
Zein powder 16-20 part.
9. nutritive powder according to claim 8, it is characterised in that, it is 100-200 object dried powder that described mulberry fruit fruit powder, medlar powder, purple sweet potato powder, carrot meal, walnut kernel powder, soyflour, wheat germ powder, Zein powder are degree of grinding.
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| CN201511001827.5A CN105614764B (en) | 2015-12-29 | 2015-12-29 | A kind of preparation method of mulberry fruit capsule of nano and the nutrient powder being made from it |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN106798333A (en) * | 2017-01-20 | 2017-06-06 | 中山森谱生物科技有限公司 | A kind of mulberry fruit polyphenol microcapsules, its preparation method and application |
| CN107348480A (en) * | 2017-05-19 | 2017-11-17 | 云南雪域印象生物科技有限公司 | Walnut oil microcapsule albumen powder |
| CN107897714A (en) * | 2017-11-21 | 2018-04-13 | 想念食品股份有限公司 | Anti-oxidant wheat germ powder and preparation method thereof |
| CN109222069A (en) * | 2018-08-10 | 2019-01-18 | 江苏省农业科学院 | A kind of anthocyanidin nano-complex and preparation method thereof of " core-shell structure copolymer " structure |
| CN109363170A (en) * | 2018-09-14 | 2019-02-22 | 中国热带农业科学院海口实验站 | The preparation method of hill gooseberry's anthocyanidin microcapsules |
| CN109091409A (en) * | 2018-10-25 | 2018-12-28 | 福建农林大学 | A kind of preparation method of passionflower anthocyanidin and ovalbumin peptide facial mask dry powder |
| CN109091409B (en) * | 2018-10-25 | 2021-09-21 | 福建农林大学 | Preparation method of passion flower anthocyanin and egg albumin peptide mask dry powder |
| CN109602025A (en) * | 2018-11-26 | 2019-04-12 | 华中农业大学 | A kind of production method for the energy ball mixing microencapsulation mulberry fruit polyphenol |
| CN112493489A (en) * | 2020-12-21 | 2021-03-16 | 广东省农业科学院蚕业与农产品加工研究所 | Preparation method of synbiotics |
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