CN105602998A - Preparation method and application of water-soluble natural nitric monoxide - Google Patents
Preparation method and application of water-soluble natural nitric monoxide Download PDFInfo
- Publication number
- CN105602998A CN105602998A CN201610029995.3A CN201610029995A CN105602998A CN 105602998 A CN105602998 A CN 105602998A CN 201610029995 A CN201610029995 A CN 201610029995A CN 105602998 A CN105602998 A CN 105602998A
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- water
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- nitric oxide
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- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title abstract 5
- 238000000855 fermentation Methods 0.000 claims abstract description 23
- 230000004151 fermentation Effects 0.000 claims abstract description 23
- 150000001875 compounds Chemical class 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 20
- 108010082495 Dietary Plant Proteins Proteins 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000004140 cleaning Methods 0.000 claims abstract description 7
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 5
- 201000010099 disease Diseases 0.000 claims abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 5
- 230000035622 drinking Effects 0.000 claims abstract description 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims description 56
- 241000894006 Bacteria Species 0.000 claims description 28
- 230000009286 beneficial effect Effects 0.000 claims description 28
- 238000004519 manufacturing process Methods 0.000 claims description 20
- 241000196324 Embryophyta Species 0.000 claims description 12
- 238000011081 inoculation Methods 0.000 claims description 7
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 4
- 241000092668 Artemisia capillaris Species 0.000 claims description 3
- 235000008658 Artemisia capillaris Nutrition 0.000 claims description 3
- 244000063299 Bacillus subtilis Species 0.000 claims description 3
- 244000068988 Glycine max Species 0.000 claims description 3
- 235000010469 Glycine max Nutrition 0.000 claims description 3
- 244000302512 Momordica charantia Species 0.000 claims description 3
- 235000009811 Momordica charantia Nutrition 0.000 claims description 3
- 235000009812 Momordica cochinchinensis Nutrition 0.000 claims description 3
- 235000018365 Momordica dioica Nutrition 0.000 claims description 3
- 241000235342 Saccharomycetes Species 0.000 claims description 3
- 235000014655 lactic acid Nutrition 0.000 claims description 3
- 239000004310 lactic acid Substances 0.000 claims description 3
- 238000005516 engineering process Methods 0.000 abstract description 5
- 206010020772 Hypertension Diseases 0.000 abstract description 3
- 206010008118 cerebral infarction Diseases 0.000 abstract description 3
- 208000026106 cerebrovascular disease Diseases 0.000 abstract description 3
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 3
- 239000006041 probiotic Substances 0.000 abstract 4
- 235000018291 probiotics Nutrition 0.000 abstract 4
- 239000004475 Arginine Substances 0.000 abstract 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 240000002234 Allium sativum Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 235000004611 garlic Nutrition 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P3/00—Preparation of elements or inorganic compounds except carbon dioxide
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/70—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter
- A23L2/84—Clarifying or fining of non-alcoholic beverages; Removing unwanted matter using microorganisms or biological material, e.g. enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation method of water-soluble natural nitric monoxide. The preparation method includes the steps of S1, selecting vegetable protein raw materials containing a great quantity of arginine, cleaning the raw materials, pulverizing and placing the pulverized raw materials in a fermentation room for standby use; S2, selecting probiotics fermented by multiple kinds of plants and cultivating compound probiotics according to a preset proportion; S3, inoculating the compound probiotics obtained in the S2 onto the raw materials obtained in the S1, adding water and performing constant-temperature fermentation at the temperature of 28-32 DEG C so as to obtain a great quantity of water-soluble nitric monoxide. The preparation method of the water-soluble natural nitric monoxide has the advantages that according to the preparation method which is obviously different from an existing fermentation technology, material selection is quite important, the developed and reserved special probiotics are inoculated, a great quantity of water-soluble nitric monoxide is prepared and stored during fermentation within preset time, and fermentation liquor produced after fermentation contains abundant ferment, so that diseases related to blood vessels, such as hypertension, diabetes and cerebral infarction can be improved during drinking.
Description
Technical field
The present invention relates to plant enzyme technical field, relate in particular to the nitric oxide production preparation method of a kind of water-soluble natural and application.
Background technology
Current plant fermentation technology a part of raw material that can ferment, but can not produce nitric oxide and by present science and technology to artificial being injected in beverage or food and medicine of the useful nitric oxide of human body, and produce the also no exploitation of technology that keeps useful nitric oxide production product, moreover raw material used are all from general plant, to collect to go out popular product by low-cost production. Therefore the present invention proposes the nitric oxide production preparation method of a kind of water-soluble natural and application.
Summary of the invention
The object of the invention is the shortcoming existing in prior art in order to solve, and the nitric oxide production preparation method of a kind of water-soluble natural and the application that propose, technique is simple, and cost is low.
To achieve these goals, the present invention has adopted following technical scheme:
The nitric oxide production preparation method of a kind of water-soluble natural, comprises the steps;
S1, selection: choose the raw material that contain a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain water-soluble nitric oxide in a large number.
Preferably, the raw material of the vegetable protein in S1 can be selected Artemisia capillaris, balsam pear and soya bean.
Preferably, in S2, the beneficial bacterium of plant fermentation is selected lactic acid bacteria bacillus subtilis, saccharomycete.
Preferably, the water depth that adds in S3 is 50 times that raw material is stacked height, and Xiang Shuizhong energising.
The nitric oxide production application of a kind of water-soluble natural, the zymotic fluid of generation is to contain abundant ferment, can improve the disease of associated blood vessel while drinking.
The present invention, by the plant fermentation of beneficial bacterium, manufactures nitric oxide production method and related products thereof and produces; The present invention ferment produce useful ferment and nitric oxide, can produce the beverage useful to health, food and medicine. Technique of the present invention is simple, cost is low, there is a zymotechnique to have obvious difference than both, first select raw material very important, next is the special beneficial bacterium inoculation of developing reservation, produces and preserve a large amount of water-soluble natural nitric oxides by the sweat at Preset Time, and the zymotic fluid that fermentation produces is to contain abundant ferment, while drinking, can improve the disease of associated blood vessel, as hypertension, diabetes, cerebral infarction etc.
Brief description of the drawings
Fig. 1 is the structural representation of the nitric oxide production preparation method of a kind of water-soluble natural that proposes of the present invention.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further explained.
Embodiment mono-
With reference to Fig. 1, the nitric oxide production preparation method of a kind of water-soluble natural that the present embodiment proposes, comprises the steps;
S1, selection: choose the Artemisia capillaris that contains a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain the water-soluble nitric oxide that contains in a large number garlic perfume (or spice).
Embodiment bis-
With reference to Fig. 1, the nitric oxide production preparation method of a kind of water-soluble natural that the present embodiment proposes, comprises the steps;
S1, selection: choose the soya bean that contains a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain water-soluble nitric oxide in a large number, except producing the beverage useful to health, food and medicine, also there is effect of kidney tonifying.
Embodiment tri-
With reference to Fig. 1, the nitric oxide production preparation method of a kind of water-soluble natural that the present embodiment proposes, comprises the steps;
S1, selection: choose the balsam pear that contains a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain water-soluble nitric oxide in a large number, except producing the beverage useful to health, food and medicine, also there is the effect of reducing internal heat.
Embodiment tetra-
With reference to Fig. 1, the nitric oxide production preparation method of a kind of water-soluble natural that the present embodiment proposes, comprises the steps;
S1, selection: choose the raw material that contain a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, as lactic acid bacteria bacillus subtilis, saccharomycete, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain water-soluble nitric oxide in a large number.
The invention allows for the nitric oxide production application of a kind of water-soluble natural, the zymotic fluid of generation is to contain abundant ferment, can improve the disease of associated blood vessel, as hypertension, diabetes, cerebral infarction etc. while drinking.
The above; it is only preferably detailed description of the invention of the present invention; but protection scope of the present invention is not limited to this; any be familiar with those skilled in the art the present invention disclose technical scope in; be equal to replacement or changed according to technical scheme of the present invention and inventive concept thereof, within all should being encompassed in protection scope of the present invention.
Claims (5)
1. the nitric oxide production preparation method of water-soluble natural, is characterized in that, comprises the steps;
S1, selection: choose the raw material that contain a large amount of arginic vegetable proteins, after cleaning up, also pulverize, be placed in fermenting cellar for subsequent use;
S2, cultivate compound beneficial bacterium: choose the beneficial bacterium of various plants fermentation, by the cooperation of preset ratio amount, turn out compound beneficial bacterium;
S3, inoculation fermentation: the compound beneficial bacterium in S2 is inoculated in S1 on raw material, and adds water; After 28-30 DEG C of ferment at constant temperature, obtain water-soluble nitric oxide in a large number.
2. the nitric oxide production preparation method of a kind of water-soluble natural according to claim 1, is characterized in that, the raw material of the vegetable protein in S1 can be selected Artemisia capillaris, balsam pear and soya bean.
3. the nitric oxide production preparation method of a kind of water-soluble natural according to claim 1, is characterized in that, in S2, the beneficial bacterium of plant fermentation is selected lactic acid bacteria bacillus subtilis, saccharomycete.
4. the nitric oxide production preparation method of a kind of water-soluble natural according to claim 1, is characterized in that, the water depth that adds in S3 is 50 times that raw material is stacked height, and Xiang Shuizhong energising.
5. the nitric oxide production application of water-soluble natural, is characterized in that, the zymotic fluid of generation is to contain abundant ferment, can improve the disease of associated blood vessel while drinking.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610029995.3A CN105602998A (en) | 2016-01-18 | 2016-01-18 | Preparation method and application of water-soluble natural nitric monoxide |
| PCT/CN2016/073522 WO2017124590A1 (en) | 2016-01-18 | 2016-02-04 | Preparation method and application of water-soluble natural nitric oxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610029995.3A CN105602998A (en) | 2016-01-18 | 2016-01-18 | Preparation method and application of water-soluble natural nitric monoxide |
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| CN105602998A true CN105602998A (en) | 2016-05-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610029995.3A Pending CN105602998A (en) | 2016-01-18 | 2016-01-18 | Preparation method and application of water-soluble natural nitric monoxide |
Country Status (2)
| Country | Link |
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| CN (1) | CN105602998A (en) |
| WO (1) | WO2017124590A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110353255A (en) * | 2018-04-10 | 2019-10-22 | 上海美瘦生物科技有限公司 | A kind of Chinese herbal medicine kidney tonifying ferment and preparation method thereof |
| CN111728223A (en) * | 2020-07-07 | 2020-10-02 | 西安因子元素科技有限公司 | Method for producing compound cytokine elements by fermentation |
Citations (4)
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|---|---|---|---|---|
| CN1739404A (en) * | 2004-08-27 | 2006-03-01 | 修红花 | Antihypertensive functional beverage and its prepn process |
| CN102669761A (en) * | 2011-03-10 | 2012-09-19 | 南昌大学 | Balsam pear beverage and preparation method thereof |
| CN103263018A (en) * | 2013-04-27 | 2013-08-28 | 北京中国科学院老专家技术中心 | Nitric oxide functional beverage and preparation method thereof |
| CN104940933A (en) * | 2015-06-15 | 2015-09-30 | 青岛大学附属医院 | Medicine used for preventing and treating cardiovascular disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273057A (en) * | 1999-05-06 | 2000-11-15 | 田三德 | Fermented soybean beverage |
| CN1476770A (en) * | 2003-07-14 | 2004-02-25 | 福建师范大学 | Preparation technique of sour soybean curd |
| CN1254196C (en) * | 2004-04-28 | 2006-05-03 | 中国农业大学 | Fermented bean curd and its preparing method |
| ES2773928T5 (en) * | 2008-01-04 | 2023-06-28 | Nestle Sa | Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancement of cognitive and related functions |
| CN101933972A (en) * | 2010-08-20 | 2011-01-05 | 王亭 | Nitric oxide reinforcing agent and application thereof |
| CN102845529A (en) * | 2012-01-10 | 2013-01-02 | 北京和美科盛生物技术有限公司 | Composite probiotic fermented soybean milk beverage for effectively reducing blood lipid and preparation method |
-
2016
- 2016-01-18 CN CN201610029995.3A patent/CN105602998A/en active Pending
- 2016-02-04 WO PCT/CN2016/073522 patent/WO2017124590A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1739404A (en) * | 2004-08-27 | 2006-03-01 | 修红花 | Antihypertensive functional beverage and its prepn process |
| CN102669761A (en) * | 2011-03-10 | 2012-09-19 | 南昌大学 | Balsam pear beverage and preparation method thereof |
| CN103263018A (en) * | 2013-04-27 | 2013-08-28 | 北京中国科学院老专家技术中心 | Nitric oxide functional beverage and preparation method thereof |
| CN104940933A (en) * | 2015-06-15 | 2015-09-30 | 青岛大学附属医院 | Medicine used for preventing and treating cardiovascular disease |
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| 余元勋: "《中国分子心脏病学》", 31 August 2015, 安徽科学技术出版社 * |
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| WO2017124590A1 (en) | 2017-07-27 |
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