CN105596785A - 一种治疗皮肤角化症的中药组合物 - Google Patents
一种治疗皮肤角化症的中药组合物 Download PDFInfo
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Abstract
本发明公开了一种治疗皮肤角化症的中药组合物，其中药原料及重量份配比为：白蒺藜10-30份，荆芥10-20份，白及5-15份，蛇床子10-20份，石斛10-20份，龙船花5-15份，白鲜皮10-20份，南蛇藤根10-20份，蝉蜕5-15份，丹参10-20份，柽柳10-20份，地榆5-15份，凤仙花10-20份，紫草10-20份，地肤子5-15份，红藤5-15份，独叶岩珠10-20份，柳叶10-20份，红参5-15份，滑石10-20份，鸡血藤10-20份，玄参10-20份，甘草5-15份。本发明中药组合物具有滋养肌肤、活络散瘀、驱风止痒、清热解毒的功效，其治疗皮肤角化症疗效显著，作用可靠。
Description
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品，尤其是一种治疗皮肤角化症的中药组合物。
背景技术
皮肤角化症是以表皮角化过度为主要变化的一组皮肤病。可表现局部皮肤角质增生、皮肤干燥，有鳞屑、皲裂，一般无主观不适，有时可有瘙痒或疼痛，常在冬季加重。本病病程多是慢性，治疗较困难，多数只能对症治疗。目前，临床上治疗皮肤角化症多采用去角质膏药，如A酸、果酸、水杨酸及尿素，需使用较长时间才能见效，且费用高。
中医认为，皮肤角化症多由湿热内蕴，外受热邪，进而熏蒸肺系，蕴结肌肤而发。
根据中医理论，针对皮肤角化症的发病机理，以滋润肌肤、活络散瘀、驱风止痒为治则，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有采用去角质膏治疗皮肤角化症存在见效慢、费用高的不足，本发明提供一种配制方便、药源广、成本低、疗效显著、作用可靠、无副作用的治疗皮肤角化症的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗皮肤角化症的中药组合物，其特征在于：其中药原料及重量份配比为：白蒺藜10-30份，荆芥10-20份，白及5-15份，蛇床子10-20份，石斛10-20份，龙船花5-15份，白鲜皮10-20份，南蛇藤根10-20份，蝉蜕5-15份，丹参10-20份，柽柳10-20份，地榆5-15份，凤仙花10-20份，紫草10-20份，地肤子5-15份，红藤5-15份，独叶岩珠10-20份，柳叶10-20份，红参5-15份，滑石10-20份，鸡血藤10-20份，玄参10-20份，甘草5-15份。
本发明的优选技术方案是：一种治疗皮肤角化症的中药组合物，其特征在于：其中药原料及重量份配比为：白蒺藜20份，荆芥15份，白及10份，蛇床子15份，石斛15份，龙船花10份，白鲜皮15份，南蛇藤根15份，蝉蜕10份，丹参15份，柽柳15份，地榆10份，凤仙花15份，紫草15份，地肤子10份，红藤10份，独叶岩珠15份，柳叶15份，红参10份，滑石15份，鸡血藤15份，玄参15份，甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：白蒺藜具有平肝解郁、祛风明目的功效；荆芥具有解表散风、透疹、消疮、止血的功效；白及具有补肺、止血、消肿、生肌、敛疮的功效；蛇床子具有温肾壮阳、燥湿、祛风、杀虫的功效；石斛具有益胃生津、滋阴清热的功效；龙船花具有散瘀止血、调经、降压的功效；白鲜皮具有清热燥湿、祛风解毒的功效；南蛇藤根具有祛风胜湿、行气散血、消肿解毒的功效；蝉蜕具有散风除热、宣肺定痉的功效；丹参具有活血调经、祛瘀消痈、清心除烦、养血安神的功效；柽柳具有疏风散寒、解表止咳、升散透疹、祛风除湿、消痞解酒的功效；地榆具有凉血止血、清热解毒、消肿敛疮的功效；凤仙花具有活血止痛、利湿消肿、解毒、行瘀降气、软坚散结的功效；紫草具有清热凉血、活血化瘀、解毒透疹的功效；地肤子具有利小便、清湿热的功效；红藤具有清热解毒、活血通络、败毒散瘀、祛风杀虫的功效；独叶岩珠具有滋阴清热、解毒消肿的功效；柳叶具有清热解毒、解毒透疹、利尿通淋的功效；红参具有大补元气、复脉固脱、益气摄血的功效；滑石具有利尿通淋、清热解暑、祛湿敛疮的功效；鸡血藤具有补血活血、舒经通络的功效；玄参具有凉血滋阴、泻火解毒的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍，在作用上相辅相成，具有协同作用，共奏滋养肌肤、活络散瘀、驱风止痒、清热解毒之功效，对皮肤角化症达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。其遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率90%，治愈率达67.5%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗皮肤角化症的中药组合物，其中药原料及重量配比为：白蒺藜20g，荆芥15g，白及10g，蛇床子15g，石斛15g，龙船花10g，白鲜皮15g，南蛇藤根15g，蝉蜕10g，丹参15g，柽柳15g，地榆10g，凤仙花15g，紫草15g，地肤子10g，红藤10g，独叶岩珠15g，柳叶15g，红参10g，滑石15g，鸡血藤15g，玄参15g，甘草10g。
实施例2
一种治疗皮肤角化症的中药组合物，其中药原料及重量配比为：白蒺藜10g，荆芥20g，白及5g，蛇床子20g，石斛10g，龙船花15g，白鲜皮10g，南蛇藤根20g，蝉蜕5g，丹参20g，柽柳10g，地榆15g，凤仙花10g，紫草20g，地肤子5g，红藤15g，独叶岩珠10g，柳叶20g，红参5g，滑石20g，鸡血藤10g，玄参20g，甘草5g。
实施例3
一种治疗皮肤角化症的中药组合物，其中药原料及重量配比为：白蒺藜30g，荆芥10g，白及15g，蛇床子10g，石斛20g，龙船花5g，白鲜皮20g，南蛇藤根10g，蝉蜕15g，丹参10g，柽柳20g，地榆5g，凤仙花20g，紫草10g，地肤子15g，红藤5g，独叶岩珠20g，柳叶10g，红参15g，滑石10g，鸡血藤20g，玄参10g，甘草15g。
实施例4
一种治疗皮肤角化症的中药组合物，其中药原料及重量配比为：白蒺藜15g，荆芥18g，白及8g，蛇床子18g，石斛12g，龙船花13g，白鲜皮12g，南蛇藤根18g，蝉蜕8g，丹参18g，柽柳12g，地榆13g，凤仙花12g，紫草18g，地肤子8g，红藤13g，独叶岩珠12g，柳叶18g，红参8g，滑石18g，鸡血藤12g，玄参18g，甘草8g。
实施例5
一种治疗皮肤角化症的中药组合物，其中药原料及重量配比为：白蒺藜25g，荆芥12g，白及13g，蛇床子12g，石斛18g，龙船花8g，白鲜皮18g，南蛇藤根12g，蝉蜕13g，丹参12g，柽柳18g，地榆8g，凤仙花18g，紫草12g，地肤子13g，红藤8g，独叶岩珠18g，柳叶12g，红参13g，滑石12g，鸡血藤18g，玄参12g，甘草13g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约6厘米，水沸后煎煮15～20分钟。两次煎煮去渣取汁，合并。
本发明以实施例1所给出的一种治疗皮肤角化症的中药组合物，做临床疗效总结如下：
一、一般性资料：本发明中药组合物应用于临床观察病例80例，其中男50例，女30例，年龄15～60岁。
二、诊断标准：
1、多见于青春发育期的男、女青年；
2、皮损主要发生于双上臂伸侧，对称性分布，病情重者也发生于双大腿伸侧或臀部；
3、皮肤干燥，有毛囊角化性小丘疹，密集成片，触之粗糙似锉刀状，呈正常肤色或淡红色；
4、冬季病情稍重，夏季病情减轻，冬季常伴有皮肤瘙痒症。
三、用法用量：临床应用时，一天一剂，水煎两遍取汁约300ml，分早、晚两次饭前半小时温热服用，五天一疗程。
四、疗效标准：
1、治愈：皮肤恢复光滑，瘙痒完全消失，各症状消失；
2、好转：症状和体征明显减轻；
3、未愈：症状和体征无明显变化。
五、治疗效果：该临床观察病例中，服药2-10个疗程，治愈54例，好转18例，未愈8例。治疗期间未发生毒副作用。
六、典型病例：
病例1：梁某，男，49岁。自述双臂后侧及臀部皮肤初始粗糙，一个月后自觉瘙痒，有鳞状皮屑掉落。服用本发明的中药组合物制备的药剂2个疗程后，皮屑明显减少；继续服用3个疗程，症状消失，皮肤恢复平滑，治愈。
病例2：王某，女，15岁，自述初起腿部汗毛弯曲无法钻出毛孔，皮肤表面粗糙，每个汗毛孔就是一个黑色小凸起，手抠后汗毛才可露出皮肤，后来有少量鳞状皮屑蜕落及轻微瘙痒。服用本发明的中药组合物制备的药剂3个疗程后，皮屑和凸起消失，皮肤光滑；续服2个疗程后，各症状消失，治愈。
Claims (2)
1.一种治疗皮肤角化症的中药组合物，其特征在于：其中药原料及重量份配比为：白蒺藜10-30份，荆芥10-20份，白及5-15份，蛇床子10-20份，石斛10-20份，龙船花5-15份，白鲜皮10-20份，南蛇藤根10-20份，蝉蜕5-15份，丹参10-20份，柽柳10-20份，地榆5-15份，凤仙花10-20份，紫草10-20份，地肤子5-15份，红藤5-15份，独叶岩珠10-20份，柳叶10-20份，红参5-15份，滑石10-20份，鸡血藤10-20份，玄参10-20份，甘草5-15份。
2.根据权利要求1所述的一种治疗皮肤角化症的中药组合物，其特征在于：其中药原料及重量份配比为：白蒺藜20份，荆芥15份，白及10份，蛇床子15份，石斛15份，龙船花10份，白鲜皮15份，南蛇藤根15份，蝉蜕10份，丹参15份，柽柳15份，地榆10份，凤仙花15份，紫草15份，地肤子10份，红藤10份，独叶岩珠15份，柳叶15份，红参10份，滑石15份，鸡血藤15份，玄参15份，甘草10份。
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