CN105596638A - Traditional Chinese medicine for treating perimenopausal syndrome - Google Patents

Abstract

The invention belongs to the field of medical technology and particularly relates to a traditional Chinese medicine for treating perimenopausal syndrome. The traditional Chinese medicine consists of the following traditional Chinese medicines in parts by weight: 8-16 parts of root of Chinese crossostephium, 5-13 parts of cinnamomum parthenoxylon, 8-16 parts of platycladi seed, 8-16 parts of wilson begonia rhizome, 8-16 parts of mariscus sumatrensis, 8-16 parts of clove, 8-16 parts of ficus esquiroliana, 5-13 parts of cinnamomum mairei levl., 5-13 parts of root of blerodendron bungei steud, 5-13 parts of macrocarpa nucuma, 11-19 parts of herb of michel galingale and 4-8 parts of beechey fig leaf. The traditional Chinese medicines are combined to realize the functions of warming and tonifying thoroughfare and conception vessels, replenishing qi and activating blood, dissipating cold and invigorating spleen, resolving phlegm and dissipating mass and eliminating fixed abdominal mass and dredging collaterals and relieving pain. The traditional Chinese medicine provided by the invention has the advantage of high total effective rate when used for treating perimenopausal syndrome.

Description

A kind of Chinese medicine for the treatment of perimenopausal syndrome

Technical field

The invention belongs to medical technical field, be specifically related to a kind of Chinese medicine for the treatment of perimenopausal syndrome.

Background technology

Perimenopausal syndrome (Perimenopausalsyndrome) past claims again menopausal syndrome, refers in enclosingThe women in climacteric, comprise from menopause transition to last menstruation this period of time in 1 year, because ovarian function subtractsMove back, sex hormone level reduces, and causes organism metabolism, endocrine, neural spirit etc. unbalance, and occur each tract symptom andThe syndrome Hou Qun of sign. The main factor that affects community's quality of life of perimenopausal women is perimenopausal syndrome.

Summary of the invention

Technical problem to be solved by this invention is to avoid the existing weak point of prior art, provides a kind for the treatment of to encloseThe Chinese medicine of climacteric syndrome.

The present invention is achieved through the following technical solutions:

Treat a Chinese medicine for perimenopausal syndrome, formed by the Chinese medicine of following weight portion:

Radix Crossostephii Chinensis 8-16 part, yellow camphor tree 5-13 part, seed of Oriental arborvitae 8-16 part, Wilson Begonia Rhizome 8-16 part, false rhizoma cyperi 8-16 part, cloves 8-16Part, Ficus fulva Reinw 8-16 part, river cassia bark 5-13 part, rose glorybower root 5-13 part, Caulis mucunae Macrocarpae 5-13 part, Herb of Michel Galingale 11-19 part, beechey fig leaf4-8 part.

Preferably, the Chinese medicine of above-mentioned treatment perimenopausal syndrome, is made up of the Chinese medicine of following weight portion:

Radix Crossostephii Chinensis 10-14 part, yellow camphor tree 7-11 part, seed of Oriental arborvitae 10-14 part, Wilson Begonia Rhizome 10-14 part, false rhizoma cyperi 10-14 part, cloves10-14 part, Ficus fulva Reinw 10-14 part, river cassia bark 7-11 part, rose glorybower root 7-11 part, Caulis mucunae Macrocarpae 7-11 part, Herb of Michel Galingale 13-17 part,Beechey fig leaf 5-7 part.

Preferred, the Chinese medicine of above-mentioned treatment perimenopausal syndrome, is made up of the Chinese medicine of following weight portion:

12 parts of Radix Crossostephii Chinensis, 9 parts of yellow camphor trees, 12 parts of the seed of Oriental arborvitaes, 12 parts of Wilson Begonia Rhizomes, 12 parts of false rhizoma cyperis, 12 parts of cloves, Ficus fulva Reinw 12Part, 9 parts, river cassia bark, 9 parts of rose glorybower roots, 9 parts of Caulis mucunae Macrocarpaes, 15 parts of Herb of Michel Galingale, 6 parts of beechey fig leafs.

The Chinese medicine of above-mentioned treatment perimenopausal syndrome, the dosage form of described Chinese medicine is oral formulations.

Through science, screening obtains the ratio of above weight proportion, for especial patient, as severe or light disease, obesityOr the patient of slight of stature, can be corresponding the proportioning of amount of adjustment composition, increase or reduce being no more than 100%, drug effect is substantially constant.

The weight portion of said medicine, if taking g as unit, the normally consumption of 1 dose.

The taboo item of medicine of the present invention: treatment period in a medicine fasting is greasy, raw and cold, the smelling of fish or mutton, irritant and be difficult for disappearingThe food of changing.

In the each component of Chinese medicine for the treatment of perimenopausal syndrome of the present invention:

Radix Crossostephii Chinensis is feverfew lotus chrysanthemum Crossostephiumchinense (L.) Mak.ExCham.EtSchltr.'sRoot. Taste is pungent; Bitter; Slightly warm in nature. Function is dispelled dehumidifying; Warming middle energizer to relieve pain. Main air pain of dampness syndrome; Neck abdomen crymodynia.

Yellow camphor tree another name camphorwood, Chinese pepper, oily camphor tree, great Ye camphor tree, smelly camphor tree, borneol tree. For the yellow camphor tree of canellaCinnamomumporrectum(Poxb.)Kosterm.[LaurusporrectaRoxb.;Cinnamomumparthenoxylum (Jack) Nees] root, bark or leaf. Taste is pungent; Micro-hardship; Warm in nature. Return lung; Spleen; Liver Channel.Function expelling wind and clearing away cold; Warming middle energizer to relieve pain; The promoting flow of qi and blood circulation. Main anemofrigid cold; Arthralgia due to wind-dampness; Stomach cold stomachache; Have loose bowels; Dysentery; Fall to beat and damageWound; Irregular menstruation.

Wilson Begonia Rhizome another name common brick grass, tassel flower, drum-shaped stone blocks, Wei Shi begonia are Begoniaceae plant Wilson Begonia Rhizome begoniaBegoniawilsoniiGagn. rhizome. Taste is sweet; Bitter; Cold nature. Function nourishes blood and enriches blood; Blood stasis removing analgesic. Main weak after being ill; LaborWound; The deficiency of blood is through closing; Perimenopausal syndrome; Leukorrhea; Spit blood; Spitting of blood; Bleeding from five sense organs or subcutaneous tissue; Traumatism and bleeding; Treating swelling and pain by traumatic injury.

False rhizoma cyperi is sedge conferted sawgrass herb Mariscussumatrensis(Retz.) rhizome and the root of T.Koyama.Taste is pungent; Warm in nature. The function promoting flow of qi and blood circulation; Menstruction regulating and pain relieving; Dispel rheumatism. Main irregular menstruation; Perimenopausal syndrome; Postpartum abdominal pain;Traumatic injury; Arthralgia due to wind-dampness; Flu.

The Ficus fulva Reinw another name tiger palm, crow wind, amnesty mother-in-law tree, hair, derive from moraceae plants Ficus fulva ReinwFicusfulvaReiuw., be used as medicine with root skin. Nature and flavor are sweet, flat. Function strengthening the spleen and replenishing qi, promoting blood circulation by removing wind. Cure mainly deficient qi and blood, uterusSagging, prolapse of the anus, oedema, arthralgia due to wind-dampness, have loose bowels in loose stool.

River cassia bark is canella Cinnamomum mairei Levl. CinnamomummaireiL é vl.[C.argenteumGamble] bark.Taste is pungent; Sweet; Warm in nature. Function is warming channel and expelling cold; The promoting flow of qi and blood circulation; Pain relieving. Main anemofrigid cold; Stomachache with cool feeling; Dysmenorrhoea; Fengshi Guanjie painBitterly; Traumatic injury; Fracture.

Rose glorybower root is called smelly maple root, is dicotyledon medicine Verbenaceae clerodendrum bungeiClerodendronbungeiSteud. root. Taste is arduous; Warm in nature. Return liver; Spleen; Kidney; Lung channel. Function promoting the circulation of qi invigorating the spleen; Dispel the wind and removeWet; Removing toxicity for detumescence; Hypotensive. The stagnant abdominal distension of staple food; Dizzy; Hiss and cough; Outer dysentery prolapse of the anus; Blood under perianal abscess; Under stranguria with turbid discharge band; Rheumatalgia; PinGas; Swollen ulcer drug; Dermatitis rhus; High blood pressure.

Caulis mucunae Macrocarpae another name wang mucuna stem, sargentodoxa cuneata, blood rattan, he good dragon. For the long pod mucuna of legumeMucunamacrcocarpaWall.[M.castaneaMerr.; M.wangiiHu] old stem. Bitter; Puckery; Cool in nature. Enter liver, kidneyTwo warps. Function is enriched blood and is invigorated blood circulation; Clearing away the lungheat and moisturizing; Clearing and activating the channels and collaterals. Main anaemia; Have through uncomfortable; Lung-heat type cough; Hemoptysis; Soreness of waist and knee joint; WindPain of dampness syndrome; Numb in every limb; Paralysis.

Herb of Michel Galingale another name revolves clever nutgrass flatsedge, revolves squama nutgrass flatsedge, derives from Cyperaceae Herb of Michel Galingale Cyperusmichelianus(L.)Link[ScirpusmichelianusL.], with all herbal medicine. Light, pungent, flat. Function promoting the circulation of qi menstruation regulating. Cure mainly dysmenorrhoea, pass the appointed time through rowOr January 2～3 persons.

Beechey fig leaf is stem, the leaf of moraceae plants Fructus Fici Beecheyanae. Sweet light, temperature, nontoxic. Enter lung, spleen, kidney three warps. Function bowl spares benefitGas, invigorating the spleen for eliminating dampness, strengthens muscles and bones, detumescence, promoting blood circulation and detoxication. Control rheumatic arthritis, a little less than the middle deficiency of vital energy, qi and blood is on the decline, and four limbs are aching and limp, muscleBone is unfavorable, traumatic injury, and through closing, alactation.

In medicine of the present invention, other medicines all record in 2015 editions one of Chinese pharmacopoeia.

Perimenopausal syndrome is because hypo-ovaria, sex hormone level reduce, cause organism metabolism, endocrine,Neural spirit etc. are unbalance. In prescriptions of traditional Chinese medicine of the present invention, Radix Crossostephii Chinensis, yellow camphor tree warming middle energizer to relieve pain; River cassia bark warming meridian to activate yang; Yellow hairBanyan, beechey fig leaf bowl spares invigorating the spleen; The seed of Oriental arborvitae, Wilson Begonia Rhizome, false rhizoma cyperi, rose glorybower root, Herb of Michel Galingale nourishes blood and battalion, stasis-dispelling and pain-killing, reduce phlegmDissipating bind; Caulis mucunae Macrocarpae, cloves moisturize fall contrary. All medicines share and play altogether that temperature compensation punching is appointed, qi and activate blood circulation, loose cold invigorating the spleen, reducing phlegm and resolving masses disappear note of the ancient Chinese,The merit of removing obstruction in channels to relieve pain. Be used for the treatment of perimenopausal syndrome, have no adverse reaction, avoided obesity, the cancer of the uterus, breast cancer etc. perniciousThe generation of pathology.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands thisBright, but therefore do not limit the present invention.

Embodiment 1

Treat a Chinese medicine for perimenopausal syndrome, concrete medicine and weight proportion are as follows:

Radix Crossostephii Chinensis 12g, yellow camphor tree 9g, seed of Oriental arborvitae 12g, Wilson Begonia Rhizome 12g, false rhizoma cyperi 12g, cloves 12g, Ficus fulva Reinw 12g, river cassia bark9g, rose glorybower root 9g, Caulis mucunae Macrocarpae 9g, Herb of Michel Galingale 15g, beechey fig leaf 6g.

Embodiment 2

Treat a Chinese medicine for perimenopausal syndrome, concrete medicine and weight proportion are as follows:

Radix Crossostephii Chinensis 10g, yellow camphor tree 7g, seed of Oriental arborvitae 10g, Wilson Begonia Rhizome 10g, false rhizoma cyperi 10g, cloves 10g, Ficus fulva Reinw 10g, river cassia bark7g, rose glorybower root 7g, Caulis mucunae Macrocarpae 7g, Herb of Michel Galingale 13g, beechey fig leaf 5g.

Embodiment 3

Treat a Chinese medicine for perimenopausal syndrome, concrete medicine and weight proportion are as follows:

Radix Crossostephii Chinensis 14g, yellow camphor tree 11g, seed of Oriental arborvitae 14g, Wilson Begonia Rhizome 14g, false rhizoma cyperi 14g, cloves 14g, Ficus fulva Reinw 14g, osmanthus, riverSkin 11g, rose glorybower root 11g, Caulis mucunae Macrocarpae 11g, Herb of Michel Galingale 17g, beechey fig leaf 7g.

Embodiment 4

Treat a Chinese medicine for perimenopausal syndrome, concrete medicine and weight proportion are as follows:

Radix Crossostephii Chinensis 8g, yellow camphor tree 5g, seed of Oriental arborvitae 8g, Wilson Begonia Rhizome 8g, false rhizoma cyperi 8g, cloves 8g, Ficus fulva Reinw 8g, river cassia bark 5g, smellyTree peony root 5g, Caulis mucunae Macrocarpae 5g, Herb of Michel Galingale 11g, beechey fig leaf 4g.

Embodiment 5

Treat a Chinese medicine for perimenopausal syndrome, concrete medicine and weight proportion are as follows:

Radix Crossostephii Chinensis 16g, yellow camphor tree 13g, seed of Oriental arborvitae 16g, Wilson Begonia Rhizome 16g, false rhizoma cyperi 16g, cloves 16g, Ficus fulva Reinw 16g, osmanthus, riverSkin 13g, rose glorybower root 13g, Caulis mucunae Macrocarpae 13g, Herb of Michel Galingale 19g, beechey fig leaf 8g.

The Chinese medicine for the treatment of perimenopausal syndrome of the present invention has been carried out to clinical pharmacodynamics test, and Details as Follows:

1 data and method

1.1 this group of physical data cases totally 80 examples, age 40-55 year, average 48 years old, the course of disease 3 months～2 years.

1.2 diagnostic criteria

1.2.1 Western medicine diagnose standard climacteric: 1. the age is the women of 40～55 one full year of life; 2. paramenia is more than 3 monthsOr 3 months～1 year person of amenorrhea; 3. occur that vasomotor symptoms is as hectic fever, sweating etc.; 4. serum reproductive hormones horizontal detectionMeet the change of climacteric, ovarian follicle estrogen (FSH) 25.8～134.8U/L, luteotropic hormone (LH) 7.7-58.5U/L, estradiol (E2) < 201pmol/L.

1.2.2 tcm diagnosis standard 1. age of onset generally before and after 45～55 one full year of life menopause. 2. there are paramenia, tideThe diseases such as hot side is red, warm perspiration, excited, emotion-thought abnormal, paresthesia of skin.

1.2.3 the women of inclusive criteria age 4O～55 year old; Meet Diseases of WM diagnostic criteria and the Syndrome in TCM mark of waiting to see the doctorAccurate person; To this research informed consent person.

1.2.4 following or more than 55 years old person of 40 years old exclusion standard age; Previously there are hyperthyroidism, diabetes, high blood pressure, hatThe serious internal disease such as worry; Postoperative and the genital malignant tumor patient of uterectomy; Psychiatric patient; Previously in 3 monthsThere are wine or drug abuse or dependence; Within nearly 3 months, take estrogen, antidepression, antipsychotic or monoamine oxidase preparation.

1.3 criterion of therapeutical effect paramenias, hectic fever is flushing, warm perspiration, excited, emotion-thought abnormal, dermal sensation are differentThe symptom such as normal all disappears for curing; Symptom is most of to disappear, and occasionally has slight discomfort for effective; Symptom is invalid without being improved as.

1.4 methods for the treatment of

1.4.1 all patients of conventional therapy all give oryzanol, vitamin B compound₆。

1.4.2 treatment by Chinese herbs treatment group gives the Chinese medicine of the embodiment of the present invention 1,1 dose of every day, is decocted in water for oral dose, and serve on 3 monthsIt is a course for the treatment of.

The all data of 1.5 statistical method adopt SPSS13.0 statistical software statistics. Data are with mean ± standard deviation (x± s) represent there is statistical significance taking P < O.O5 as difference.

2 results

2.1 clinical efficacies were treated after 1 course for the treatment of, cured l5 example, accounted for 18.75%, and effective 37 examples, account for 46.25%, effective 26 examples,Account for 32.50%, invalid 2 examples, account for 2.50%, and total effective rate is 97.50%.

Before and after 2.2 treatments, before variation E2, the FSH of blood hormones, LH treatment, be respectively (2.56 ± 6.23) pmol/L,(87.46 ± 12.59) U/L and (73.35 ± 12.09) U/L, be respectively (62.34 ± 6.56) pmol/L, (53.24 after treatment± 11.34) U/L and (52.24 ± 9.35) U/L, difference has statistical significance (P < 0.05).

Claims (3)

1. treat a Chinese medicine for perimenopausal syndrome, formed by the Chinese medicine of following weight portion:

Radix Crossostephii Chinensis 8-16 part, yellow camphor tree 5-13 part, seed of Oriental arborvitae 8-16 part, Wilson Begonia Rhizome 8-16 part, false rhizoma cyperi 8-16 part, cloves 8-16Part, Ficus fulva Reinw 8-16 part, river cassia bark 5-13 part, rose glorybower root 5-13 part, Caulis mucunae Macrocarpae 5-13 part, Herb of Michel Galingale 11-19 part, beechey fig leaf4-8 part.

2. the Chinese medicine for the treatment of perimenopausal syndrome according to claim 1, is characterized in that, in following weight portionMedicine composition:

Radix Crossostephii Chinensis 10-14 part, yellow camphor tree 7-11 part, seed of Oriental arborvitae 10-14 part, Wilson Begonia Rhizome 10-14 part, false rhizoma cyperi 10-14 part, cloves10-14 part, Ficus fulva Reinw 10-14 part, river cassia bark 7-11 part, rose glorybower root 7-11 part, Caulis mucunae Macrocarpae 7-11 part, Herb of Michel Galingale 13-17 part,Beechey fig leaf 5-7 part.

3. the Chinese medicine for the treatment of perimenopausal syndrome according to claim 3, is characterized in that, in following weight portionMedicine composition:

12 parts of Radix Crossostephii Chinensis, 9 parts of yellow camphor trees, 12 parts of the seed of Oriental arborvitaes, 12 parts of Wilson Begonia Rhizomes, 12 parts of false rhizoma cyperis, 12 parts of cloves, Ficus fulva Reinw 12Part, 9 parts, river cassia bark, 9 parts of rose glorybower roots, 9 parts of Caulis mucunae Macrocarpaes, 15 parts of Herb of Michel Galingale, 6 parts of beechey fig leafs.