CN105596044B - Soft tissue fixation devices containing absorbable screw - Google Patents
Soft tissue fixation devices containing absorbable screw Download PDFInfo
- Publication number
- CN105596044B CN105596044B CN201610051820.2A CN201610051820A CN105596044B CN 105596044 B CN105596044 B CN 105596044B CN 201610051820 A CN201610051820 A CN 201610051820A CN 105596044 B CN105596044 B CN 105596044B
- Authority
- CN
- China
- Prior art keywords
- soft tissue
- absorbable screw
- conduit
- fixation devices
- tissue fixation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00889—Material properties antimicrobial, disinfectant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B2017/0647—Surgical staples, i.e. penetrating the tissue having one single leg, e.g. tacks
- A61B2017/0648—Surgical staples, i.e. penetrating the tissue having one single leg, e.g. tacks threaded, e.g. tacks with a screw thread
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
Abstract
The present invention relates to a kind of soft tissue fixation devices containing absorbable screw, belong to the technical field of medical instrument.Soft tissue fixation devices of the present invention containing absorbable screw include driving device, nail pipe, drive rod；The nail pipe is outer to be bolted with conduit, and more absorbable screws are provided in the conduit.It is formed with helicitic texture on the nail beam of the absorbable screw, and is provided with lead spring on the helicitic texture, more absorbable screws are packed into the conduit with helicla flute according to concatenated sequence end to end；By cocking when use, drive rod can be driven to rotate under the driving of the driving device, and then in laparoscopic hernia repair operation, the absorbable screw can one by one be launched the conduit.Soft tissue fixation devices of the present invention containing absorbable screw are performed the operation especially suitable for laparoscopic hernia repair, and have the characteristics that prevent adhesion, convenient and reliable operation；And the conduit is dismountable replacement part, it is i.e. reusable which only needs to change conduit after.
Description
Technical field
The present invention relates to the technical field of medical instrument, it is more particularly related to a kind of containing absorbable screw
Soft tissue fixation devices.
Background technique
Incisional hernia (incisional hernia) refers to that abdominal visceral browser or tissue are to cut open from abdominal incision hernia outstanding
The common complication of abdomen operation；Wherein, following abdominal midline incision incidence is higher, mostly occurs in abdomen stringer cutout regions, sees
In the notch of disruption of wound, infection, healing by second intention, when minority betides no disruption of wound medical history and occurs longer after surgery
Between after.Its disease incidence is about up to 2-11%, and incisional hernia incidence may be up to 40% or so after wound infects.Incision of abdominal wall
Hernia is based on operative treatment, and the method for repairing and mending of incisional hernia is the open neoplasty and abdomen with or without the use of artificial mesh at present
Hysteroscope Incision hernia repair.The simple tissue postoperative incisional hernia recurrence rate of suture repair still may be up to 20-50%.According to incision of abdominal wall
Hernia country principle of classification, clinic in-it is big, even Huge Incisional Hernia Treated is relatively conventional, and such incisional hernia mostly uses artificial mesh
Tension-free hernia is carried out, incisional hernia recurrence rate effectively can be reduced to 10% or so.Laparoscope and open neoplasty
Compare, has the following characteristics that
(1) laparoscopic incision herniorrhaphy follows abdominal hernia surgical principle, meets the bioengineering power for reinforcing rear wall repairing
Principle is learned, Postoperative recurrent rate is up to < 5%.(2) operative approach reduces the machine of implantation material site infection far from former incisional hernia
Meeting once has the infected particularly with notch.(3) abdominal wall tissue is not required to free destruction extensively, and preservation stomach wall is original strong as far as possible
Degree, is more suitable for recurrent incisional hernia.(4) it is still remained between hernia defect point skin and artificial mesh and does not destroy the soft of blood supply
Tissue, effectively covering compressing artificial mesh, grow into polypropylene coarse mesh conducive to fibr tissue, improve artificial mesh and stomach wall group
The Healing strength knitted.(5) hernial content that dissociates in pneumoperitoneum is more intuitive clear, and gravity naturally droops hernial content,
It can avoid the passive situation of damage intestinal tube.(6) intraperitoneal to be easier to find invisible " pin hole hernia ", art caused by reducing thus
Recurrent hernia afterwards.(7) the fixed sticking patch of abdominal cavity in seaming nail multiple spot, even tension dispersion are lowered.(8) sticking patch implanted region is cut without skin
Mouthful, reduce the possibility that hemotoncus hydrops occurs, it is not necessary to it is conventional to place drainage tube, reduce opportunities for contamination.(9) non-stomach wall through and through suture
Fixed sticking patch person, postoperative pain mild degree, duration are short, and patient restores rapid.(10) laparoscopic surgery is reducing notch sense
Achieve the effect that while dye, reduction Postoperative recurrent rate minimally invasive.(11) laparoscopic surgery technical requirements are high, need relatively long
Learning curve.Based on the above feature, laparoscopic incision herniorrhaphy is gradually concerned by people in recent years, in treatment incisional hernia
When it is more more and more universal.The method of the fixed sticking patch of laparoscope neoplasty has complete suture, complete stitching, suture and stitching and adhesive
It is fixed etc., it there is no unified standard to standardize at present.
In the prior art, TYCO Healthcare discloses a kind of mirror use in patent application 200810009395.6
Stapler and disposable nail kit.John Isbell Shipp discloses a kind of for solid in US 2007/0038220A1
Determine the absorbable spiral nail of hernia patch, the absorbable spiral nail is made of the copolymer of lactide and glycolide.Davol,
Inc., Cranston, RI disclose a kind of method and apparatus that surgical operation is fixed in US 2007/0250064A1.
SOFRADIMPRODUCTION, Trevoux (FR) disclose a kind of I shape operation anchor in US 2003/0187465A1.
Origin Medsystems, Inc.Menlo park, Calif disclose a kind of surgery helical fastener in US5366479A.
The application of above-mentioned fixator solves the problems such as time-consuming of suture repairing, inconvenience.Simultaneously can also reduce patient blood loss and
Wound.Traditional surgical fixator is staple type, and the fixed deformation of staple type needs iron felt or other structures, and structure is more
Complexity, and price is higher.There is a piercing point in single-sided helix nail distal end, and there is a T-bar in proximal end, and T-bar has divided spiral nail equally
Diameter, provide a stress surface.Another form of spiral nail is two-sided spiral, and distally there are two point is pierced into, proximal end has
One connection strap, connection strap is connected to two spiral coils, while having divided the diameter of two spiral coils equally.In the prior art, Gu
It is usually disposable to determine device structure, frictionally damage may be generated to tissue when in addition operating.
Summary of the invention
In order to solve the above technical problems existing in the prior art, containing the purpose of the present invention is to provide one kind can inhale
Receive the soft tissue fixation devices of nail.
In order to achieve the above-mentioned object of the invention, the invention adopts the following technical scheme:
A kind of soft tissue fixation devices containing absorbable screw, including handle and tension spring, trigger, driving gear,
Large helical gear, bevel pinion, nail pipe and drive rod；The first end of the tension spring is stuck in the fixed column of the handle inner wall
On, the second end of the tension spring is stuck on the upper end of the trigger, the upper end side of the trigger by a rotation axis with
The inner wall of the handle is rotatably coupled, the upper end other side of the trigger be equipped with matched with the driving gear it is oblique
Tooth, the trigger extend from inside to outside from the handle and the lower end of the trigger are located at outside the handle；The big helical teeth
Wheel is arranged concentrically with the driving gear, and the large helical gear passes through the sliding tooth wheel drive；The large helical gear
The external tooth of external tooth and the bevel pinion cooperates；The drive rod is driven by the rotation axis of the bevel pinion, and the drive
The nail pipe is arranged outside lever, the first end of the nail pipe is arranged in the handle, and the second end of the nail pipe is arranged in institute
It states outside handle, the second end of the nail pipe is detachably connected with conduit, is provided with absorbable screw in the conduit；It is described to inhale
It receives and is formed with helicitic texture on the nail beam of nail, and be provided with lead spring on the helicitic texture.
In the present invention, lubricant coating is provided on the conduit.Be arranged on conduit the lubricant coating be conducive to by
The conduit of the soft tissue fixation devices containing absorbable screw is smoothly sent into tissue, and prevents adhesion.?
In the prior art, the lubricant coating or Antiblock coating, such as silicone oil, such as dimethyl silicone polymer.In the present invention, institute
State and be deposited with the lubricant coating containing Teflon on conduit, and the lubricant coating with a thickness of 3-5 μm.It is described to lubricate compatible painting
Layer surface hardness is Hv500~Hv1000, and skin-friction coefficient is 0.1~0.05.The lubricant coating also contains stable polymerization
Object, the polymer are selected from polymethyl methacrylate, polyacrylamide, polyacrylonitrile, polyetheramides, polyethyene diamine, poly- carbon
Acid esters, polyethylene ketone, polyvinylether, polyvinyl ester, polyvinylpyrrolidone, polyethylene, polypropylene, polytetrafluoroethylene (PTFE), polyene
Olefin elastomer, polyisobutene, fluorosilicone, carboxymethyl chitosan, polyethylene terephthalate, poly- valerate, carboxymethyl are fine
It is poly- to tie up element, hydroxyethyl cellulose, cellulose butyrate, cellulose acetate-butyrate, ethyl-vinyl acetate copolymer, chitosan and shell
One of sugar derivatives is a variety of.Optionally contain antibacterial agent in the lubricant coating.The antibacterial agent for example can be often
Silver-based antimicrobial agent or non-silver-based antimicrobial agent.As the example of silver-based antimicrobial agent, such as it can be Argent grain, based on the nature of glass
The silver antibacterial agent of carrier or silver antibacterial agent based on Zeolite support.The antibacterial agent can be added to by conventional mixed method
In composition, and by coating in the lubrication compatiblizing coatings being dispersed in.It can be prevented or inhibited and be taken by using antibacterial agent
The growth of the microorganism of band, to prevent from infecting caused by because of fixed operation.
Wherein, the absorbable screw is made of degradation material；The degradation material is selected from poly- (L- lactide), gathers
(D, L- lactide), poly- (L- lactide-co-d, L- lactide), poly- (d,L-lactide-co-glycolide), poly- (glycolide),
Poly- (L- lactide-co-glycolide), poly- (glycolide -co- trimethylene carbonate), poly- (L- lactide-co-trimethylene carbon
Acid esters), poly- (D, L- lactide-co-trimethylene carbonate), poly- (L- lactide-co-caprolactone), poly- (amino acid), poly-
(6-caprolactone), poly- (6- valerolactone), poly- (gamma-butyrolacton), poly- (beta-hydroxy-butanoic acid ester), poly- (DL-LACTIC ACID), poly- (L- cream
Acid), ethylene carbonate (1,3-dioxolane -2- ketone), propylene carbonate (4- methyl-1,3- dioxolan-2-one), carbonic acid 1,
At least one of the Asia 3- propyl ester (1,3- dioxanes -2- ketone) and butylene carbonate (1,3- Dioxepane -2- ketone).
Preferably, the degradation material includes the poly- [carbonic acid (butylene-co- 6-caprolactone) of 10~15wt%
Ester] (PBCL) and 80-90wt% poly lactide-glycolide acid (PLGA)；And the poly lactic-co-glycolic acid copolymerization
Object is synthesized by PDLA and PGA, and the molar ratio of the PDLA and PGA are 40: 60.Preferably, the degradation material also contains
There is the n-hydroxysuccinimide sulfonate sodium of 1~5wt%.
Compared with prior art, the soft tissue fixation devices of the present invention containing absorbable screw have below beneficial to effect
Fruit:
Soft tissue fixation devices of the present invention containing absorbable screw are performed the operation especially suitable for laparoscopic hernia repair, and
Have the characteristics that prevent adhesion, convenient and reliable operation；The conduit is dismountable replacement part in the present invention, is only needed more after use
It is i.e. reusable to change conduit.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the soft tissue fixation devices containing absorbable screw of one embodiment of the invention.
Fig. 2 is the enlarged structure schematic diagram in Fig. 1 at circle A.
Specific embodiment
The soft tissue fixation devices of the present invention containing absorbable screw are done into one below with reference to specific embodiment
The elaboration of step, to help those skilled in the art to have more complete, accurate to inventive concept of the invention, technical solution and go deep into
Understanding.
As shown in Figs. 1-2, described in the present embodiment containing the soft tissue fixation devices of absorbable screw, including handle 10, with
And tension spring 1, trigger 2, driving gear 3, large helical gear 4, bevel pinion 5, nail pipe 6 and drive rod 7.The tension spring 1
First end be stuck in the fixed column of 10 inner wall of handle, the second end of the tension spring 1 is stuck in the upper end of the trigger 2
On, the upper end side of the trigger 2 is rotatably coupled by a rotation axis and the inner wall of the handle 10, the trigger 2
The upper end other side is equipped with the helical teeth matched with the driving gear 3, and the trigger 2 extends simultaneously from inside to outside from the handle 10
So that the lower end of the trigger 2 is located at outside the handle 10；The large helical gear 4 is arranged concentrically with the driving gear 3, and
The large helical gear 4 is driven by the driving gear 3；The external tooth of the large helical gear 4 and the external tooth of the bevel pinion 5 are matched
It closes；The drive rod 7 is driven by the rotation axis of the bevel pinion 5, and is arranged the nail pipe 6 outside the drive rod 7, described
The first end for following closely pipe 6 is arranged in the handle 10, and the second end of the nail pipe 6 is arranged outside the handle 10, the nail pipe 6
Second end be threaded with conduit 8, be provided with absorbable screw 9 in the conduit 8.It is formed on the nail beam of the absorbable screw
Helicitic texture, and lead spring is provided on the helicitic texture, specifically more absorbable screws are according to concatenated end to end
Sequence is packed into the conduit with helicla flute, and the head of absorbable screw is towards the outlet of conduit.In the present embodiment, described to pull
Machine, tension spring, driving gear, large helical gear and bevel pinion constitute the soft tissue of the present invention containing absorbable screw and fix
The driving device of device.By cocking when use, drive rod can be driven to rotate under the driving of the driving device, into
And in laparoscopic hernia repair operation, the absorbable screw can one by one be launched the conduit.
In the present invention, lubricant coating is provided on the conduit.Be arranged on conduit the lubricant coating be conducive to by
The conduit of the soft tissue fixation devices containing absorbable screw is smoothly sent into tissue, and prevents adhesion.?
In the prior art, the lubricant coating or Antiblock coating, such as silicone oil, such as dimethyl silicone polymer.In the present invention, institute
State and be deposited with the lubricant coating containing Teflon on conduit, and the lubricant coating with a thickness of 3-5 μm.It is described to lubricate compatible painting
Layer surface hardness is Hv500~Hv1000, and skin-friction coefficient is 0.1~0.05.The lubricant coating also contains stable polymerization
Object, the polymer are selected from polymethyl methacrylate, polyacrylamide, polyacrylonitrile, polyetheramides, polyethyene diamine, poly- carbon
Acid esters, polyethylene ketone, polyvinylether, polyvinyl ester, polyvinylpyrrolidone, polyethylene, polypropylene, polytetrafluoroethylene (PTFE), polyene
Olefin elastomer, polyisobutene, fluorosilicone, carboxymethyl chitosan, polyethylene terephthalate, poly- valerate, carboxymethyl are fine
It is poly- to tie up element, hydroxyethyl cellulose, cellulose butyrate, cellulose acetate-butyrate, ethyl-vinyl acetate copolymer, chitosan and shell
One of sugar derivatives is a variety of.Optionally containing the antibacterial agent of 0.01-1.5wt% in the lubricant coating.The antibacterial
Agent for example can be common silver-based antimicrobial agent or non-silver-based antimicrobial agent.As the example of silver-based antimicrobial agent, such as it can be silver
Particle, the silver antibacterial agent based on nature of glass carrier or the silver antibacterial agent based on Zeolite support.The antibacterial agent can pass through routine
Mixed method be added in composition, and by the lubrication compatiblizing coatings that are dispersed in of coating.By using antibacterial agent
The growth of the microorganism of carrying can be prevented or inhibited, to prevent from infecting caused by because of fixed operation.
In the present invention, the absorbable screw is made of degradation material；As illustratively, the degradation material is selected
Autohemagglutination (L- lactide), poly(D,L-lactide), poly- (L- lactide-co-d, L- lactide), poly- (D, L- lactide-co-second
Lactide), poly- (glycolide), poly- (L- lactide-co-glycolide), poly- (glycolide -co- trimethylene carbonate), poly- (L- third
Lactide -co- trimethylene carbonate), poly- (D, L- lactide-co-trimethylene carbonate), poly- (L- lactide-co-is in oneself
Ester), poly- (amino acid), poly- (6-caprolactone), poly- (δ-valerolactone), poly- (gamma-butyrolacton), poly- (beta-hydroxy-butanoic acid ester), poly-
(DL-LACTIC ACID), poly (L-lactic acid), ethylene carbonate (1,3-dioxolane -2- ketone), propylene carbonate (4- methyl-1,3- dioxy
Penta ring -2- ketone), carbonic acid 1, the Asia 3- propyl ester (1,3- dioxanes -2- ketone) and butylene carbonate (1,3- Dioxepane -2- ketone)
At least one of.
As with improvement, the degradation material includes the poly- [carbonic acid (butylene-co- 6-caprolactone) of 10~15wt%
Ester] (PBCL) and 80-90wt% poly lactide-glycolide acid (PLGA)；And the poly lactic-co-glycolic acid copolymerization
Object is synthesized by PDLA and PGA, and the molar ratio of the PDLA and PGA are 40: 60.Preferably, the degradation material also contains
There is the n-hydroxysuccinimide sulfonate sodium of 1~5wt%.Static degradation, which is carried out, using hanks' balanced salt solution tests table
It is bright, the degradation material weightlessness can be made stable at 80~90 days up to 90% time by adding PBCL, had excellent
Stability to degradation, and irritation is small, and compatibility is good, and addition n-hydroxysuccinimide sulfonate sodium may advantageously facilitate being cured for hernia
It closes.
In the present invention, the absorbable screw is prepared by the technique of raw material mixing, melting extrusion and machining.
As illustratively, it will mix, be uniformly mixed in the raw material components investment batch mixer of degradation material；Temperature is controlled when mixing
Degree is at 80 DEG C or less.Melting extrusion, each section of temperature of the single screw extrusion machine are carried out using screw extruder after mixture is cooling
Degree is 150~210 DEG C.Gained melt blending material squeezes out post-processing into pole, and Mechanics Performance Testing shows the drawing of the pole
Stretching intensity can achieve 50~60MPa, and bending strength can achieve 100-120MPa.Pole after the stretching is pressed into a fixed length
After degree is cut into section, lathe process is carried out according to thread parameter and bolt structure, the absorbable screw can be obtained.In the present invention
The shape of the absorbable screw use bolt structure commonly used in the art, as global shape first half be cone,
Latter half is cylindricality or generally truncated cone-shaped, it is accurately positioned convenient for guide pin when operation.There is no special limit to thread parameter
System, preferably deep and blunt screw thread.
For the ordinary skill in the art, specific embodiment is only exemplarily described the present invention,
Obviously the present invention specific implementation is not subject to the restrictions described above, as long as use the inventive concept and technical scheme of the present invention into
The improvement of capable various unsubstantialities, or not improved the conception and technical scheme of the invention are directly applied to other occasions
, it is within the scope of the present invention.
Claims (6)
1. a kind of soft tissue fixation devices containing absorbable screw, it is characterised in that: including handle and tension spring, trigger,
Drive gear, large helical gear, bevel pinion, nail pipe and drive rod；The first end of the tension spring is stuck in the handle inner wall
Fixed column on, the second end of the tension spring is stuck on the upper end of the trigger, and the upper end side of the trigger passes through one
Rotation axis and the inner wall of the handle are rotatably coupled, and the upper end other side of the trigger is equipped with and the driving gear phase
The helical teeth of cooperation, the trigger extend from inside to outside from the handle and the lower end of the trigger are located at outside the handle；Institute
It states large helical gear to be arranged concentrically with the driving gear, and the large helical gear passes through the sliding tooth wheel drive；It is described big
The external tooth of helical gear external tooth and the bevel pinion cooperates；The drive rod is driven by the rotation axis of the bevel pinion, and
And the nail pipe is arranged outside the drive rod, the first end of the nail pipe is arranged in the handle, the second end of the nail pipe
It is arranged outside the handle, the second end of the nail pipe is detachably connected with conduit, is provided with absorbable screw in the conduit；
It is formed with helicitic texture on the nail beam of the absorbable screw, and is provided with lead spring on the helicitic texture；It is described to inhale
It receives nail to be made of degradation material, the degradation material includes that [(butylene-co- ε-is in oneself for carbonic acid for 10~15wt% poly-
Ester) ester] and 80-90wt% poly lactide-glycolide acid；And the poly lactide-glycolide acid is by PDLA
It is synthesized with PGA, the molar ratio of the PDLA and PGA are 40: 60.
2. the soft tissue fixation devices according to claim 1 containing absorbable screw, it is characterised in that: sink on the conduit
Product has a lubricant coating containing Teflon, and the lubricant coating with a thickness of 3-5 μm.
3. the soft tissue fixation devices according to claim 2 containing absorbable screw, it is characterised in that: the lubricant coating
Surface hardness is Hv500~Hv1000, and skin-friction coefficient is 0.1~0.05.
4. the soft tissue fixation devices according to claim 2 containing absorbable screw, it is characterised in that: the lubricant coating
Also containing stablizing polymer, the polymer be selected from polymethyl methacrylate, polyacrylamide, polyacrylonitrile, polyetheramides,
Polyethyene diamine, polyethylene ketone, polyvinylether, polyvinyl ester, polyvinylpyrrolidone, polyethylene, polypropylene, gathers polycarbonate
Tetrafluoroethene, polyolefin elastomer, polyisobutene, fluorosilicone, carboxymethyl chitosan, polyethylene terephthalate, poly- penta
Acid esters, carboxymethyl cellulose, hydroxyethyl cellulose, cellulose butyrate, cellulose acetate-butyrate, ethyl-vinyl acetate copolymer,
One of chitosan and chitosan derivatives are a variety of.
5. the soft tissue fixation devices according to claim 2 containing absorbable screw, it is characterised in that: the lubricant coating
Also contain antibacterial agent.
6. the soft tissue fixation devices according to claim 1 containing absorbable screw, it is characterised in that: the degradable material
The material also n-hydroxysuccinimide sulfonate sodium containing 1~5wt%.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610051820.2A CN105596044B (en) | 2016-01-25 | 2016-01-25 | Soft tissue fixation devices containing absorbable screw |
| US15/142,952 US10702264B2 (en) | 2016-01-25 | 2016-04-29 | Fixing device for soft tissue |
| EP16168443.6A EP3195811B1 (en) | 2016-01-25 | 2016-05-04 | Fixing device for soft tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610051820.2A CN105596044B (en) | 2016-01-25 | 2016-01-25 | Soft tissue fixation devices containing absorbable screw |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105596044A CN105596044A (en) | 2016-05-25 |
| CN105596044B true CN105596044B (en) | 2019-01-25 |
Family
ID=55976792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610051820.2A Active CN105596044B (en) | 2016-01-25 | 2016-01-25 | Soft tissue fixation devices containing absorbable screw |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105596044B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5289963A (en) * | 1991-10-18 | 1994-03-01 | United States Surgical Corporation | Apparatus and method for applying surgical staples to attach an object to body tissue |
| CN101347348A (en) * | 2008-08-28 | 2009-01-21 | 上海创亿医疗器械技术有限公司 | Spiral thread nail for repair technique |
| US10335146B2 (en) * | 2014-04-02 | 2019-07-02 | Coviden Lp | Surgical fastener applying apparatus, kits and methods for endoscopic procedures |
| US20150305738A1 (en) * | 2014-04-28 | 2015-10-29 | Covidien Lp | Surgical fastener having a cap |
-
2016
- 2016-01-25 CN CN201610051820.2A patent/CN105596044B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105596044A (en) | 2016-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6396402B2 (en) | Self-holding variable loop suture | |
| CN103068324B (en) | Have cut maintenance thorn from retention system | |
| CN101172050B (en) | Long term bioabsorbable barbed sutures | |
| US9295463B2 (en) | Shape memory fasteners and method of use | |
| CN105496482B (en) | Absorbable plate and the soft tissue fixation devices containing Absorbable plate | |
| CN105596043B (en) | Titanium nail and the soft tissue fixation devices containing titanium nail | |
| CN105596044B (en) | Soft tissue fixation devices containing absorbable screw | |
| US20220071621A1 (en) | Tapered transition portion for suture needles | |
| EP3195811B1 (en) | Fixing device for soft tissue | |
| CA3192005A1 (en) | Curved suture needles having a non-smooth profile | |
| US20230052272A1 (en) | Systems and methods for suturing | |
| CN201418758Y (en) | Suture instrument of cavity mirror mini-invasive surgery | |
| US20240057996A1 (en) | Suturing device | |
| CN219021332U (en) | Suture winding board device | |
| US20220378416A1 (en) | Curved suture needle extension | |
| US20230083808A1 (en) | Suture needles with flexible and non-flexible components | |
| CN116898508A (en) | Polymer modified absorbable suture line | |
| Matičić et al. | Comparative study of skin closure in dogs with polypropylene and polyglactin 910 | |
| RU74284U1 (en) | A device for bandaging a small ventricle in the treatment of obesity and gastroesophageal reflux disease | |
| CN105559840A (en) | Soft tissue fixing device containing titanium nails | |
| De Jong | Suture options in gynaecological surgery |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |