CN105581901A - Human body main and collateral channel detection positioning system and method - Google Patents
Human body main and collateral channel detection positioning system and method Download PDFInfo
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- CN105581901A CN105581901A CN201610048724.2A CN201610048724A CN105581901A CN 105581901 A CN105581901 A CN 105581901A CN 201610048724 A CN201610048724 A CN 201610048724A CN 105581901 A CN105581901 A CN 105581901A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/02—Devices for locating such points
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Abstract
The invention discloses a human body main and collateral channel detection positioning system and method. The system comprises a laser diode, a photomultiplier, a lock-in amplifier, an optical switch, optical fiber, a light source controller and a computer. The photomultiplier, the lock-in amplifier and the computer are sequentially connected. The laser diode is used for emitting short-pulse laser light which enters the human body tissue surface to produce diffused light. The optical fiber collects the diffused light and then transmits the diffused light to the photomultiplier. The photomultiplier carries out multiplication amplification on the received light signals to form electric signals and then transmits the electric signals to the lock-in amplifier. The lock-in amplifier extracts out weak electric signals with the specific frequency in the received electric signals, and the extracted weak electric signals with the specific frequency are converted into digital signals through analog-digital conversion and then transmitted to the computer through a serial port to be analyzed and treated. The computer receives and stores the digital signal data and analyzes and treats the digital signals. The system can achieve precise detection positioning for the human body main and collateral channels. The invention further discloses the human body main and collateral channel detection positioning method.
Description
Technical field
The present invention relates to a kind of optical characteristics detection method of human body information, specifically refer to a kind of collaterals of human detection and locationSystem and method, is applicable to the human body information high-acruracy survey of large area multizone.
Background technology
According to organism optical theory, when after laser incident tissue, enter tissue light will with tissue interaction, a partLight is absorbed by tissue decay until disappear, and another part light will the continuous last diffusion of scattering go out body surface in tissue, and this part is unrestrainedThe information that the light of ejaculation body surface has carried organization internal, the diffused light that therefore gathers and analyze body surface not only can draw not on the same groupThe optical characteristics of knitting, and can utilize the difference of optical characteristics to differentiate different tissues.
With respect to domestic published patent CN102349853B, this patent drags optical fiber by stepper motor and changes differentMeasurement point, this mode need to be to measure in darkroom, but this will affect tested personnel's mood in darkroom, and this can leadCause the inaccurate of measurement result. Separately, because motor is difficult to adjust the fore-and-aft distance between optical fiber and tested tissue, this also can affect surveyAmount result.
Three-wavelength mensuration, because tissue has different spectral characteristics to the light of different frequency, one of them rippleLong measured value as a reference, can calculate the difference of another two wavelength measurement values and reference wavelength measured value. Compare single wavelengthMethod, the method can improve certainty of measurement.
Summary of the invention
One of object of the present invention is to provide a kind of collaterals of human detection and location system, and this system architecture is simple, operation sideJust, can realize the accurate detection and location to collaterals of human.
Above-mentioned purpose of the present invention realizes by following technical solution: a kind of collaterals of human detection and location system, itsBe characterised in that: this system comprise laser diode, photomultiplier, lock-in amplifier, photoswitch, optical fiber, light source controller andComputer, described light source controller is used for controlling laser diode, and described photoswitch is used for controlling the switching of optical fiber, described inPhotomultiplier, lock-in amplifier and computer be connected successively, described laser diode is used for sending short-pulse laser, entersBe mapped to tissue surface, produce diffused light, described optical fiber is transferred to described photomultiplier after collecting diffused light, and photoelectricity doublyIncrease after the optical signal multiplication of reception is zoomed into the signal of telecommunication by pipe and be transferred to described lock-in amplifier, lock-in amplifier is receivingThe ultra-weak electronic signal of the CF in the signal of telecommunication extracts, the faint telecommunications of the CF extracting by analog-to-digital conversion handleAfter number converting data signal to, be transferred to described Computer Analysis processing through serial ports, described computer receives and preserves digitally to be believedNumber, carries out analyzing and processing to data signal, thereby draws the region that collaterals of human exists, and realizes the detection to collaterals of humanLocation.
The present invention can adopt single wavelength measurement, also can adopt three-wavelength to measure, and concrete structure is as follows:
Described laser diode is one, and the wavelength of the short-pulse laser that this laser diode sends is 805nm, described inOptical fiber be one, optical fiber and laser diode are at a distance of 3cm, incident laser and optical fiber are all perpendicular to tissue to be measured.
Described laser diode is three, and the wavelength of the short-pulse laser that three laser diodes send is respectively730nm, 805nm and 890nm, three laser diodes are equilateral triangle to be arranged, and described optical fiber is one, is positioned at equilateral triangleCenter, optical fiber and laser diode are all at a distance of 3cm, incident laser and optical fiber are all perpendicular to tissue to be measured.
In the present invention, the ultra-weak electronic signal of described CF refers to that frequency is the signal of telecommunication of 20Hz.
In the present invention, when described computer carries out analyzing and processing to data signal, choose measured zone, from measured zoneHigh order end start measure, the sensing point of measured zone high order end is made as to first measurement point, from left to right successively measure, afterThereby the measurement point of face and first measurement point comparison draw relative intensity value, the computing formula of relative intensity value as shown in Equation 1,
The wherein measured value of the current measurement point of I, dIaBe the measured value of first point, a is relative intensity value,
(μ x) carries out Nonlinear Quasi to the relative intensity value obtaining to recycling Origin software application exponential function y=expClose, each measurement point obtains a μ value, i.e. decay factor asks arithmetic average to be put down the decay factor of a measured zoneAll decay factors, if it is all large than the middle average attenuation factor to record the average attenuation factor of both sides, in can judging soBetween region be channels and collaterals region, with this, collaterals of human is positioned. In collaterals of human detection and location system of the present invention, laser twoThe laser that level pipe sends incides tissue surface, switches to total photoswitch, then by collecting after optical fiber is collected through photoswitchInput to photomultiplier, photomultiplier is a kind of special vacuum extremely responsive to ultraviolet light, visible ray and near infrared lightPipe. It can make the faint optical signal entering be enhanced to originally 108 times, makes optical signal energy measured. Photomultiplier is by glassThe vacuum plant of glass encapsulation, comprises photocathode, several dynodes and an anode in it. Incident photon clashes into photoelectricity the moonThe utmost point, produces photoelectric effect, and the photoelectron of generation is focused onto dynode. Thereafter operation principle is as electron multiplier,Electronics is accelerated to dynode and produces multiple secondary electrons, and the potential difference of common each dynode is at 100 to 200 voltsSpecial. Secondary electron flows as cascaded, makes electron multiplication through a series of dynode, finally arrives anode. GenerallyThe dynode of photomultiplier is separate type, and the dynode of electron multiplier is continous way. Photomultiplier transitThe effect of pipe is mainly adding multistage amplification in photoelectric process, optical signal being converted to the signal of telecommunication, thereby putThe signal of telecommunication after large, then this signal of telecommunication lock-in amplifier of coming in and going out.
Lock-in amplifier is a kind of amplifier that alternating signal is carried out to phase sensitive detection. It utilizes and measured signal has identicalThe reference signal of frequency and phase relation benchmark as a comparison, only same frequently, same with those and reference signal to measured signal itselfThe noise component(s) of phase has response. Therefore, can significantly suppress useless noise, improve detection signal-to-noise ratio. In addition, lock-in amplifier hasVery high detection sensitivity, signal is processed fairly simple, is a kind of effective ways of low light level signal detection. The reference signal hereThat diode controller produces identical with the light on and off frequency of laser diode by laser. This frequency can be passed through laser diodeIts size of controller, setting this frequency is 20Hz, lock-in amplifier can lock this frequency of 20Hz. Irradiating after human bodySignal is as measured signal. Lock-in amplifier, this frequency of 20Hz benchmark as a comparison, carries out detection to measured signal, therebyExtract the signal that this frequency of 20Hz is carried. Lock-in amplifier converts data signal by analog-to-digital conversion to the signal extractingExport computer to by serial ports afterwards.
Computer receives and preserves digital signal data, and this value recording is the intensity of measurement point, measurement pointThereby draw relative intensity with first measurement point comparison, suc as formula 1:
(μ x) carries out nonlinear fitting to relative intensity value, obtains a series of μ values, to re-use exponential function y=expDecay factor. By rate of decay between the more different channels and collaterals of decay factor, can show that the region of channels and collaterals existence is than non-channels and collaterals districtIt is slow to decay in territory.
Two of object of the present invention is to provide a kind of collaterals of human detection and location method, and the method is easy to operate, Neng GoushiThe now accurate detection and location to collaterals of human.
Above-mentioned purpose of the present invention realizes by following technical solution: adopt above-mentioned collaterals of human detection and location systemCarry out detection and location method, it is characterized in that, the method comprises the steps:
(1) the each assembly in system is connected, laser diode and optical fiber are perpendicular to tissue to be measured, photoelectricityMultiplier tube, lock-in amplifier and computer are connected successively;
(2) send short-pulse laser by laser diode, incide tissue surface, produce diffused light;
(3) be transferred to photomultiplier after collecting diffused light by optical fiber, photomultiplier is by the optical signal multiplication receivingAfter zooming into the signal of telecommunication, be transferred to lock-in amplifier;
(4) by lock-in amplifier, the ultra-weak electronic signal in the signal of telecommunication receiving is extracted, by analog-to-digital conversion handleAfter converting data signal to, the ultra-weak electronic signal extracting is transferred to Computer Analysis processing through serial ports;
(5) receive and preserve digital signal data by computer, data signal is carried out to analyzing and processing, thereby draw peopleThe region that body channels and collaterals exist.
Brief description of the drawings
Below in conjunction with the drawings and specific embodiments, the present invention is described in further detail.
Fig. 1 is the overall structure schematic diagram of detection and location system embodiment one of the present invention;
Fig. 2 is the schematic diagram of measured zone while measuring in detection and location system embodiment one of the present invention;
Fig. 3 is part-structure schematic diagram in detection and location system embodiment one of the present invention, show laser diode, optical fiber withAnd measurement relation between tissue, be now that three-wavelength is measured structure;
Fig. 4 is part-structure schematic diagram in detection and location system embodiment two of the present invention, show laser diode, optical fiber withAnd measurement relation between tissue, be now single wavelength measurement structure.
Detailed description of the invention
Embodiment mono-
As shown in Figure 1 to Figure 3, this system comprises laser secondary to the embodiment mono-of human body channels and collaterals detection and location system of the present inventionPipe, photomultiplier, lock-in amplifier, photoswitch, optical fiber, light source controller and computer, light source controller passes through computerControl, light source controller is used for controlling laser diode, and photoswitch is for controlling the switching of optical fiber, photomultiplier, phase-lockedAmplifier And Computer is connected successively, and laser diode is used for sending short-pulse laser, incides tissue surface, producesDiffused light.
The present embodiment adopts three-wavelength to measure, and laser diode is three, and the short pulse that three laser diodes send swashsLight wavelength is respectively 730nm, 805nm and 890nm, and three laser diodes are equilateral triangle to be arranged, and optical fiber is one, is positioned atThe center of equilateral triangle, optical fiber and laser diode are all at a distance of 3cm, and incident laser and optical fiber are all perpendicular to human body group to be measuredKnit.
Optical fiber is transferred to photomultiplier after collecting diffused light, and the optical signal multiplication of reception is zoomed into electricity by photomultiplierAfter signal, be transferred to lock-in amplifier, lock-in amplifier extracts the ultra-weak electronic signal of the CF in the signal of telecommunication receiving, after converting data signal to, the ultra-weak electronic signal of the CF extracting by analog-to-digital conversion handle is transferred to computer through serial portsAnalyzing and processing, the ultra-weak electronic signal of CF refers to that frequency is the signal of telecommunication of 20Hz here, computer receives and preserves numeralSignal data, carries out analyzing and processing to data signal, thereby draws the region that collaterals of human exists, and realizes the inspection to collaterals of humanMeasure position.
In the present embodiment, the detailed process that computer carries out analyzing and processing to data signal is: as shown in Figure 2, chooseMeasured zone, starts to measure from the high order end of measured zone, and the sensing point of measured zone high order end is made as to first measurement point,Measure successively from left to right, thereby measurement point and first measurement point comparison are below drawn to relative intensity value, relative intensityValue computing formula as shown in Equation 1,
The wherein measured value of the current measurement point of I, dIaBe the measured value of first point, a is relative intensity value,
(μ is x) (taking natural constant e the end of as, taking-μ x as index for recycling Origin software application exponential function y=expFunction) the relative intensity value obtaining is carried out to nonlinear fitting, each measurement point obtains a μ value, i.e. and decay factor, oneThe decay factor of measured zone asks arithmetic average to obtain the average attenuation factor, by the average attenuation between zones of different relatively because ofSon, because the region of measuring is continuum, if the average attenuation factor that records both sides is all than the middle average attenuation factorCan judge that so zone line, as channels and collaterals region, positions collaterals of human with this greatly.
And for the measured zone at high order end or low order end place, if record measured zone flat at high order end or low order end placeAll decay factor is larger than the adjacent average attenuation factor, because now only having the average attenuation factor comparison of two measured zone, and canSo that measured zone is moved accordingly to the left or to the right, the high order end before making or the measured zone at low order end place are left accordinglyAlso there is measured zone on side or right side, then adopt above-mentioned same method to compare the average attenuation factor of measured zone,Whether the measured zone of judging high order end or low order end place with this is as channels and collaterals region.
Equally, measured zone can be a line or multirow, while there is multirow measured zone, judges the method phase in channels and collaterals regionWith, now adopt line by line and judge.
Adopt said system to carry out collaterals of human detection and location method, the method comprises the steps:
(1) the each assembly in system is connected, laser diode and optical fiber are perpendicular to tissue to be measured, photoelectricityMultiplier tube, lock-in amplifier and computer are connected successively;
(2) send short-pulse laser by laser diode, incide tissue surface, produce diffused light;
(3) be transferred to photomultiplier after collecting diffused light by optical fiber, photomultiplier is by the optical signal multiplication receivingAfter zooming into the signal of telecommunication, be transferred to lock-in amplifier;
(4) by lock-in amplifier, the ultra-weak electronic signal in the signal of telecommunication receiving is extracted, by analog-to-digital conversion handleAfter converting data signal to, the ultra-weak electronic signal extracting is transferred to Computer Analysis processing through serial ports;
(5) receive and preserve digital signal data by computer, data signal is carried out to analyzing and processing, thereby draw peopleThe region that body channels and collaterals exist.
Adopt detection and location method of the present invention to measure 30 measured, the intensity obtaining simulatesThe data result of the relative attenuation factor is as shown in table 1.
The relative attenuation factor that table 1:30 position measured's intensity simulates
From above-mentioned measurement result, the average attenuation factor in region 2 is larger than region 1, the average attenuation factor ratio in region 4Region 3 is large, and the average attenuation factor in region 6 is larger than region 5, and wherein region 2,4,6 is non-channels and collaterals regions, and region 1,3,7 is warpNetwork region.
Slower by relatively judging to decay in the region of channels and collaterals existence, can first measure conversely the flat of zones of differentAll thereby decay factor judges whether this region has channels and collaterals to exist.
The channel and collateral information of human body not only can be measured and judge to native system, and other that can also measure human body is by light diffusionThe information that method can be measured.
Embodiment bis-
The embodiment bis-of human body channels and collaterals detection and location system of the present invention as shown in Figure 4, different with embodiment mono-, this realityExecute example and adopt single wavelength measurement, laser diode is one, and the wavelength of the short-pulse laser that this laser diode sends is805nm, optical fiber is one, and optical fiber and laser diode are at a distance of 3cm, and incident laser and optical fiber are all perpendicular to human body group to be measuredKnit.
The process of embodiment bis-is identical with embodiment, is all computer control light source controllers, by light-source controller controlsThe laser diode of different wave length is lighted by specific sequential loop, and the light that laser diode sends impinges perpendicularly on tested groupKnit, be provided with diffused light at measured point and collect optical fiber, for collecting the diffused light with tested tissue signal, then collectingDiffused light be switched to photomultiplier by photoswitch, photomultiplier is transformed into the signal of telecommunication faint optical signal, then defeatedEnter to digital lock-in amplifier, the faint signal of telecommunication is extracted, digital signal is input to computer through serial ports, by calculatingMachine carries out data analysis processing.
Embodiments of the present invention are not limited to this, and all this kind is according to foregoing of the present invention, general according to this areaLogical technological know-how and customary means, not departing under the above-mentioned basic fundamental thought of the present invention prerequisite, do said structure of the present inventionAmendment, replacement or the change of other various ways going out, within all should dropping on protection scope of the present invention.
Claims (6)
1. a collaterals of human detection and location system, is characterized in that: this system comprises laser diode, photomultiplier, lockPhase amplifier, photoswitch, optical fiber, light source controller and computer, described light source controller is used for controlling laser diode, instituteThe photoswitch of stating is for controlling the switching of optical fiber, and described photomultiplier, lock-in amplifier and computer are connected successively, instituteState laser diode for sending short-pulse laser, incide tissue surface, produce diffused light, described optical fiber is collected diffusionAfter light, be transferred to described photomultiplier, photomultiplier is transferred to institute after the optical signal multiplication of reception is zoomed into the signal of telecommunicationThe lock-in amplifier of stating, lock-in amplifier extracts the ultra-weak electronic signal of the CF in the signal of telecommunication receiving, and passes throughAnalog-to-digital conversion is transferred to described computer through serial ports after the ultra-weak electronic signal of the CF extracting is converted to data signalAnalyzing and processing, described computer receives and preserves digital signal data, and data signal is carried out to analyzing and processing, thereby draws human bodyThe region that channels and collaterals exist, realizes the detection and location to collaterals of human.
2. collaterals of human detection and location system according to claim 1, is characterized in that: described laser diode is oneRoot, the wavelength of the short-pulse laser that this laser diode sends is 805nm, described optical fiber is one, optical fiber and laser secondaryPipe is at a distance of 3cm, and incident laser and optical fiber are all perpendicular to tissue to be measured.
3. collaterals of human detection and location system according to claim 1, is characterized in that: described laser diode is threeRoot, the wavelength of the short-pulse laser that three laser diodes send is respectively 730nm, 805nm and 890nm, three laser secondarysPipe is equilateral triangle to be arranged, and described optical fiber is one, is positioned at the center of equilateral triangle, and optical fiber and laser diode are all apart3cm, incident laser and optical fiber are all perpendicular to tissue to be measured.
4. collaterals of human detection and location system according to claim 1, is characterized in that: the faint electricity of described CFSignal refers to that frequency is the signal of telecommunication of 20Hz.
5. collaterals of human detection and location system according to claim 1, is characterized in that: described computer is to data signalWhile carrying out analyzing and processing, choose measured zone, start to measure from the high order end of measured zone, the detection of measured zone high order endPoint is made as first measurement point, measures successively from left to right, thereby measurement point and first measurement point comparison are below drawnRelative intensity value, the computing formula of relative intensity value as shown in Equation 1,
The wherein measured value of the current measurement point of I, dIaBe the measured value of first point, a is relative intensity value,
Recycling Origin software application exponential function y=exp (μ x) carries out nonlinear fitting to the relative intensity value obtaining,Each measurement point obtains a μ value, i.e. decay factor asks arithmetic average on average to be declined the decay factor of a measured zoneSubtracting coefficient, if it is all large than the middle average attenuation factor to record the average attenuation factor of both sides, can judge mesozone soTerritory is channels and collaterals region, with this, collaterals of human is positioned.
6. the collaterals of human detection and location system described in employing claim 1 to 5 any one is carried out detection and location method, its featureBe, the method comprises the steps:
(1) the each assembly in system is connected, laser diode and optical fiber are perpendicular to tissue to be measured, photomultiplier transitPipe, lock-in amplifier and computer are connected successively;
(2) send short-pulse laser by laser diode, incide tissue surface, produce diffused light;
(3) be transferred to photomultiplier after collecting diffused light by optical fiber, photomultiplier amplifies the optical signal multiplication receivingAfter becoming the signal of telecommunication, be transferred to lock-in amplifier;
(4) ultra-weak electronic signal in the signal of telecommunication receiving by lock-in amplifier handle extracts, and extracts by analog-to-digital conversion handleUltra-weak electronic signal be transferred to Computer Analysis processing through serial ports after converting data signal to;
(5) receive and preserve digital signal data by computer, data signal is carried out to analyzing and processing, thereby draw human body warpThe region that network exists.
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| CN201610048724.2A CN105581901B (en) | 2016-01-25 | 2016-01-25 | A kind of collaterals of human detection alignment system and method |
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| CN201610048724.2A CN105581901B (en) | 2016-01-25 | 2016-01-25 | A kind of collaterals of human detection alignment system and method |
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| CN105581901B CN105581901B (en) | 2017-09-12 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110151160A (en) * | 2019-05-20 | 2019-08-23 | 深圳市问库信息技术有限公司 | A kind of electronic channel detecting device and its detection method |
| CN110638425A (en) * | 2019-09-23 | 2020-01-03 | 北京华德恒业科技有限公司 | Intelligent hand-diagnosis imaging device and method, and computer-readable storage medium |
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| KR20030006939A (en) * | 2001-07-12 | 2003-01-23 | 삼성전자 주식회사 | Apparatus of searching acupuncture points |
| CN101002671A (en) * | 2007-01-11 | 2007-07-25 | 福建师范大学 | Transvenous optical charactr nondestructive testing method and apparatus therefor |
| CN102349853A (en) * | 2011-08-05 | 2012-02-15 | 华南师范大学 | Method for detecting and positioning channels and collaterals |
| CN203915437U (en) * | 2014-05-06 | 2014-11-05 | 华南师范大学 | A kind of automatic homing optics instrument |
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- 2016-01-25 CN CN201610048724.2A patent/CN105581901B/en not_active Expired - Fee Related
Patent Citations (4)
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|---|---|---|---|---|
| KR20030006939A (en) * | 2001-07-12 | 2003-01-23 | 삼성전자 주식회사 | Apparatus of searching acupuncture points |
| CN101002671A (en) * | 2007-01-11 | 2007-07-25 | 福建师范大学 | Transvenous optical charactr nondestructive testing method and apparatus therefor |
| CN102349853A (en) * | 2011-08-05 | 2012-02-15 | 华南师范大学 | Method for detecting and positioning channels and collaterals |
| CN203915437U (en) * | 2014-05-06 | 2014-11-05 | 华南师范大学 | A kind of automatic homing optics instrument |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110151160A (en) * | 2019-05-20 | 2019-08-23 | 深圳市问库信息技术有限公司 | A kind of electronic channel detecting device and its detection method |
| CN110638425A (en) * | 2019-09-23 | 2020-01-03 | 北京华德恒业科技有限公司 | Intelligent hand-diagnosis imaging device and method, and computer-readable storage medium |
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