CN105565239A - Fusion type filling machine - Google Patents

Fusion type filling machine Download PDF

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Publication number
CN105565239A
CN105565239A CN201610085941.9A CN201610085941A CN105565239A CN 105565239 A CN105565239 A CN 105565239A CN 201610085941 A CN201610085941 A CN 201610085941A CN 105565239 A CN105565239 A CN 105565239A
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CN
China
Prior art keywords
assembly
filling
plug
shaft assembly
cillin bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610085941.9A
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Chinese (zh)
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CN105565239B (en
Inventor
郑效东
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tofflon Science and Technology Group Co Ltd
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Shanghai Tofflon Science and Technology Co Ltd
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Priority to CN201610085941.9A priority Critical patent/CN105565239B/en
Publication of CN105565239A publication Critical patent/CN105565239A/en
Application granted granted Critical
Publication of CN105565239B publication Critical patent/CN105565239B/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations
    • B67C7/0073Sterilising, aseptic filling and closing
    • B67C7/0086Sterilisation being restricted to the area of application of the closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations
    • B67C7/0006Conveying; Synchronising
    • B67C2007/006Devices particularly adapted for container filling

Landscapes

  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention discloses a fusion type filling machine, which is characterized by comprising an x and y double-axis moving trolley assembly, a rubber plug vibration base and a linear rail vibration base assembly, wherein a filling and plug adding base is arranged above the x and y double-axis moving trolley assembly; a filling ascending and descending shaft assembly, a plug adding ascending and descending shaft assembly, a plug lifting ascending and descending shaft assembly, a plug taking rotating shaft assembly and a plug tamping ascending and descending shaft assembly are sequentially arranged on the filling and plug adding base in a penetrating way; the plug adding ascending and descending shaft assembly and the plug lifting ascending and descending shaft assembly are of a concentric shaft sleeve shaft structure; the filling ascending and descending shaft assembly is arranged at one side of the x and y double-axis moving trolley assembly; a filling needle assembly is arranged on the filling ascending and descending shaft assembly; and the filling needle assembly is communicated with a disposable medicine liquid temporary storage bag and a liquid conveying hose assembly. The fusion type filling machine has the advantages that the filling and plug adding solution of a nesting plate type pre-filling sealing injector and a nesting plate type penicillin bottle is realized through mold replacement on the same filling machine; the function of multipurpose of one machine is achieved; the utilization rate of workshops, personnel and equipment is improved; and the operation cost is reduced for a pharmaceutical factory.

Description

A kind of pattern of fusion bottle placer
Technical field
The present invention relates to a kind of can the board-like pre-embedding bottle placer of nest of compatible nest board-like cillin bottle filling and stopper-adding, this equipment is by the parts of removable parts with general purpose interface, the mutual conversion that the pre-embedding of quick realization is filling and cillin bottle is filling, belong to pharmaceutical equipment technical field, particularly aseptic injection Canning Technique field.
Background technology
Pre-embedding bottle placer is that pharmaceutical factory is used for the equipment of packing liquid medicine, is dispensed in each little pre-encapsulated injector by liquid medicine by this equipment, and automatically completes and add plug, is sealed in by liquid medicine in glass or plastic needle cylinder, is isolated from the outside.What the board-like pre-encapsulated injector of nest adopted is pre-sterilized technology, is placed in the nest plate of speciality, and with the hole that quantity does not wait on each nest plate, this some holes is used for inserting syringe.This kind of manner of packing is easy to use, and area of mill site is little, saves equipment and operating cost.
Traditional cillin bottle is filling uses common cillin bottle, and the cleaning of rear needs and sterilizing are bought in this kind of cillin bottle pharmaceutical factory, are used further to bottle placer liquid drug.
In recent years along with the universal of RTU technology and development, disposable this brand-new manner of packing of cillin bottle exempting from sterilizing also accept by vast pharmaceutical factory both domestic and external.
Because the packaging material of this kind of packaging and pre-encapsulated injector is similar, therefore pharmaceutical factory wishes the bottle placer of board-like for nest cillin bottle and the board-like pre-embedding of nest to be merged, and enables bottle placer be common to this two kinds of packaging materials.
Summary of the invention
Problem to be solved by this invention is to provide a kind of filling and stopper-adding machine that can process the board-like pre-encapsulated injector of nest and the board-like cillin bottle of nest, this equipment can reduce the floor area of pharmaceutical factory sterile workshop, reduce operating cost, reduce the up-front investment in drug research and development stage, shorten the marketing drugs time.
In order to solve the problem, technical scheme of the present invention there is provided a kind of pattern of fusion bottle placer, it is characterized in that, comprise x, y twin shaft travelling car assembly, plug vibrating base and rectilinear orbit vibrating base assembly, x, y twin shaft travelling car assembly is positioned at table midway location, can along the x-axis direction or y-axis direction move, x, filling and stopper-adding seat is provided with above y twin shaft travelling car assembly, filling and stopper-adding seat is equipped with successively filling lifting shaft assembly, to jump a queue lifting shaft assembly, carry plug lifting shaft assembly, get plug rotating shaft assembly, tamping lifting shaft assembly, wherein jump a queue lifting shaft assembly and Ti Sai lifting shaft assembly is concentric shafts cover axle construction, the side of x, y twin shaft travelling car assembly is provided with filling lifting shaft assembly, and filling lifting shaft assembly is provided with filling needle assemblies, and the top of filling needle assemblies is by for filling peristaltic pump component and disposable liquid buffer memory bag and walk liquid hose and be communicated with.Plug vibrating base and rectilinear orbit vibrating base assembly are filled in rotating shaft assembly and are connected with getting.
Preferably, described x, y twin shaft travelling car assembly is provided with the pre-encapsulated injector mould for the filling and stopper-adding of pre-encapsulated injector or the board-like cillin bottle mould of nest for the filling and stopper-adding of the board-like cillin bottle of nest; Described pre-encapsulated injector mould comprises and is fixed on x, the syringe nest plate center plate assemblies on y twin shaft travelling car assembly, the syringe plunger be fixed on filling and stopper-adding seat only stop assembly, be fixed on carry above plug lifting shaft assembly syringe rubber plug get stopper rod assembly, be fixed on that the rotation of getting above plug rotating shaft assembly is got plug assembly, is fixed on the fixing tamping bar assembly above tamping lifting shaft assembly, the syringe be fixed on above lifting shaft assembly of jumping a queue jumps a queue silica gel head group part and syringe rubber plug hopper; The board-like cillin bottle mould of described nest comprises and is fixed on x, the cillin bottle nest plate center plate assemblies on y twin shaft travelling car assembly, cillin bottle plug vibrating bunker assembly, fills in the cillin bottle that lifting shaft assembly is connected and fixed and gets stopper rod assembly, is arranged on the cillin bottle plug that cillin bottle gets below stopper rod assembly and only stops assembly with carrying.
Preferably, described syringe nest plate center plate assemblies or cillin bottle nest plate center plate assemblies are fixed on x by two tightening knobs, on y twin shaft travelling car assembly.
The solution of the present invention by following mold exchange to realize the board-like pre-encapsulated injector of nest and the board-like cillin bottle filling and stopper-adding of nest on same bottle placer, realize the function of a tractor serves several purposes, improve the degree of utilization of workshop, personnel and equipment, for pharmaceutical factory saves operating cost.
Accompanying drawing explanation
Fig. 1 is the front view of a kind of pattern of fusion bottle placer provided by the invention;
Fig. 2 is the birds-eye view of Fig. 1;
Fig. 3 is that the present invention is for front view during pre-encapsulated injector filling and stopper-adding board-like to nest;
Fig. 4 is the birds-eye view of Fig. 3;
Fig. 5 is that the present invention is for front view during cillin bottle filling and stopper-adding board-like to nest;
Fig. 6 is the birds-eye view of Fig. 5;
Fig. 7 is the structural representation of pre-encapsulated injector mould;
Fig. 8 is the structural representation of the board-like cillin bottle mould of nest.
Detailed description of the invention
For making the present invention become apparent, hereby with preferred embodiment, and accompanying drawing is coordinated to be described in detail below.
Embodiment 1
As Fig. 1, shown in 2, for a kind of fusion type bottle placer provided by the invention, it comprises x, y twin shaft travelling car assembly 1, filling and stopper-adding holder assembly 4, plug vibrating base and rectilinear orbit vibrating base assembly 17, x, y twin shaft travelling car assembly is positioned at table midway location, can along the x-axis direction or y-axis direction move, x, y twin shaft travelling car assembly 1 top position is provided with filling and stopper-adding seat 4, filling and stopper-adding seat 4 is equipped with successively filling lifting shaft assembly 5, to jump a queue lifting shaft assembly 6, carry plug lifting shaft assembly 7, get plug rotating shaft assembly 8, tamping lifting shaft assembly 9, wherein jump a queue lifting shaft assembly 6 and Ti Sai lifting shaft assembly 7 is concentric shafts cover axle construction, the different assemblies of tightening knob for installing during fixing production are all arranged at the top of all axles.X, the side of y twin shaft travelling car assembly 1 is provided with filling lifting shaft assembly, filling lifting shaft assembly is provided with filling needle assemblies 11, and the top of filling needle assemblies 11 is by for filling peristaltic pump component 16 and disposable liquid buffer memory bag and walk liquid hose 18 and be communicated with, conveying liquid time filling.
As shown in Figure 3,4, the birds-eye view of a kind of fusion type bottle placer provided for the present embodiment when pre-encapsulated injector filling and stopper-adding board-like to nest.
X, y twin shaft travelling car assembly 1 is installed the syringe nest plate center plate assemblies 2 for syringe nest plate location, be fixed on x by two tightening knobs 3, on y twin shaft travelling car assembly 1, fast demountable.Be fixed with filling needle assemblies 11 above filling lifting shaft assembly 5, fixed by tightening knob.Jump a queue and to fix syringe above lifting shaft assembly 6 and to jump a queue silica gel head group part 12, silica gel head group of jumping a queue part 12 adopts knob to fix with lifting shaft assembly 6 of jumping a queue, for convenience detach.Carry and fix syringe rubber plug above plug lifting shaft assembly 7 and get stopper rod assembly 13, get stopper rod assembly 13 with carrying and fill in lifting shaft assembly 7 and adopt knob to fix, for convenience detach.Get above plug rotating shaft assembly 8 and fix rotation and get plug assembly 14, rotating and get plug assembly front end and have non-logical circular hole, during for getting plug, placing plug.Fix tamping bar assembly 15 above tamping lifting shaft 9, tamping bar assembly and tamping lifting shaft 9 adopt knob to fix, for convenience detach.Filling and stopper-adding seat 4 is also fixed syringe plunger and only stop assembly 10.
Before production, pre-encapsulated injector is placed in nest plate and combinations of syringe 20, has 10 row 10 to arrange cylindrical hole, be placed with 100 syringes respectively in nest plate.Nest plate and combinations of syringe 20 are placed in syringe nest box 19.During production, manually brought out by nest slab integral, be placed in center plate assemblies 2, center plate has the hole corresponding with nest plate and combinations of syringe 20, the syringe on nest plate just in time inserts in the hole of center plate assemblies 2, is formed locate nest plate and combinations of syringe 20.X, y twin shaft travelling car assembly 1 load syringe nest plate center plate assemblies 2 and nest plate and combinations of syringe 20 move to immediately below filling needle assemblies 11, after filling pin and syringe vertical centering, filling lifting shaft assembly 5 declines, after filling pin gos deep into syringe, peristaltic pump 16 starts, and is loaded in syringe by the medicine liquid irrigation in liquid buffer memory bag 18.After filling, filling lifting shaft assembly 5 rises to setting height, x, y twin shaft travelling car assembly 1 load syringe nest plate center plate assemblies 2 and nest plate and combinations of syringe 20 move setpoint distance, after filling pin and first row second syringe vertical centering, repeat filling.While filling, plug vibrating base and rectilinear orbit vibrating base assembly 17 start, syringe plunger in syringe rubber plug hopper 21 is become row to output to plunger by automatic arranging only to stop assembly 10, when every row syringe filling to the 3rd time, 1st syringe of this journey is just in time positioned at the silica gel head group part 12 and get immediately below stopper rod assembly 13 of jumping a queue, synchronously, tamping assembly 15 declines fast, 1 plunger is only stopped assembly 10 from plunger to be smash the circular hole getting plug assembly 14 leading portion, getting plug assembly rotation delivers to immediately below silica gel head group valency 12 of jumping a queue by the plug in hole, now get stopper rod assembly 13 to decline, plunger is taken out and rises to setting height, then assembly 12 and assembly 13 decline simultaneously, plug delivered to syringe top open part and push to the assigned address in syringe.Nest plate and combinations of syringe 20, until by complete for syringe filling and stopper-addings all in nest plate, x, y twin shaft travelling car assembly 1 moves to initial position afterwards, manually take out and put into syringe nest box 19 by equipment crank motion, and pre-encapsulated injector is produced and terminated.
Embodiment 2
The difference of the present embodiment and embodiment 1 is, as shown in Figure 5,6 (for the birds-eye view of a kind of fusion type provided by the invention pre-embedding bottle placer when cillin bottle filling and stopper-adding board-like to nest), pre-encapsulated injector mould (as shown in Figure 7) is replaced with the board-like cillin bottle mould (as shown in Figure 8) of nest.
X, y twin shaft travelling car assembly 1 is installed the cillin bottle nest plate center plate assemblies 24 for cillin bottle nest plate location, be fixed on x by two knobs 3, on y twin shaft travelling car assembly 1, fast demountable.Carry and fix cillin bottle above plug lifting shaft assembly 7 and get stopper rod assembly 25, cillin bottle is got stopper rod assembly 25 with carrying and is filled in lifting shaft assembly 7 and adopt knob to fix, for convenience detach.Cillin bottle is got stopper rod assembly 25 and has been issued cillin bottle plug and only stop assembly 26, cillin bottle plug only stops assembly 26 and is fixed on filling and stopper-adding seat 4, for stopping the cillin bottle plug transferred out from cillin bottle plug vibrating bunker assembly 27, be convenient to cillin bottle get stopper rod assembly 25 get plug with jump a queue.
Before production, first above cillin bottle assembly is in place.
During production, cillin bottle is placed in cillin bottle nest plate combination 23, has ten row ten to arrange cylindrical hole, be placed with 100 cillin bottles respectively in cillin bottle nest plate.Cillin bottle nest plate combination 23 is placed in cillin bottle nest box 22.Manually cillin bottle nest plate is combined 23 entirety to bring out, be placed in cillin bottle center plate assemblies 24, cillin bottle center plate assemblies 24 has and combines 23 corresponding holes with cillin bottle nest plate, just in time insert in the hole of cillin bottle center plate assemblies 24 bottom cillin bottle in cillin bottle nest plate combination 23, location is formed to cillin bottle nest plate combination 23.X, y twin shaft travelling car assembly 1 load cillin bottle center plate assemblies 24 and cillin bottle nest plate combination 23 move to immediately below filling needle assemblies 11, after the filling pin of filling needle assemblies 11 and cillin bottle perpendicular alignmnet, filling lifting shaft assembly 5 declines, after filling pin stretches into cillin bottle, peristaltic pump 16 starts, and is loaded in cillin bottle by the medicine liquid irrigation in liquid buffer memory bag 18.After filling, filling lifting shaft assembly 5 rises to setting height, and the distance of setting is moved in x, y twin shaft travelling car assembly 1 load cillin bottle center plate assemblies 24 and nest plate combination 23, after filling pin and first ranked third a cillin bottle vertical centering, again filling.While filling, vibrating bunker assembly 27 starts, cillin bottle plug in hopper is become row to output to plug by automatic arranging only to stop assembly 26, when every row cillin bottle filling to the 3rd time, 1st cillin bottle of this journey is just in time positioned at cillin bottle and adds plug assembly 25 and plug only stops immediately below assembly 26, synchronously, cillin bottle adds plug assembly 25 and declines fast, the consent of putting that 1 plug only stops assembly 26 from plug is delivered to setting height, this highly just in time by the cillin bottle bottleneck close contact of plug and bottom, can form sealing.Equipment crank motion is until by complete for cillin bottle filling and stopper-addings all in nest plate, x, y twin shaft travelling car assembly 1 moves to initial position afterwards, and manually cillin bottle nest plate combination 23 taken out and put into cillin bottle nest box 22, pre-encapsulated injector is produced and terminated.

Claims (3)

1. a pattern of fusion bottle placer, it is characterized in that, comprise x, y twin shaft travelling car assembly (1), plug vibrating base and rectilinear orbit vibrating base assembly (17), x, y twin shaft travelling car assembly (1) top is provided with filling and stopper-adding seat (4), filling and stopper-adding seat (4) is equipped with successively filling lifting shaft assembly (5), to jump a queue lifting shaft assembly (6), carry plug lifting shaft assembly (7), get plug rotating shaft assembly (8), tamping lifting shaft assembly (9), wherein jump a queue lifting shaft assembly (6) and carry plug lifting shaft assembly (7) for concentric shafts cover axle construction, x, the side of y twin shaft travelling car assembly (1) is provided with filling lifting shaft assembly, filling lifting shaft assembly is provided with filling needle assemblies (11), and the top of filling needle assemblies (11) is by for filling peristaltic pump component (16) and disposable liquid buffer memory bag and walk liquid hose (18) and be communicated with.
2. pattern of fusion bottle placer as claimed in claim 1, it is characterized in that, described x, y twin shaft travelling car assembly (1) is provided with the pre-encapsulated injector mould for the filling and stopper-adding of pre-encapsulated injector or the board-like cillin bottle mould of nest for the filling and stopper-adding of the board-like cillin bottle of nest, described pre-encapsulated injector mould comprises and is fixed on x, syringe nest plate center plate assemblies (2) on y twin shaft travelling car assembly (1), the syringe plunger be fixed on filling and stopper-adding seat (4) only stops assembly (10), be fixed on carry plug lifting shaft assembly (7) top syringe rubber plug get stopper rod assembly (13), be fixed on the rotation of getting plug rotating shaft assembly (8) top and get plug assembly (14), be fixed on the fixing tamping bar assembly (15) of tamping lifting shaft assembly (9) top, the syringe being fixed on lifting shaft assembly (6) top of jumping a queue is jumped a queue silica gel head group part (12) and syringe rubber plug hopper (21), the board-like cillin bottle mould of described nest comprises and is fixed on x, cillin bottle nest plate center plate assemblies (24) on y twin shaft travelling car assembly (1), cillin bottle plug vibrating bunker assembly (27), fill in the cillin bottle that lifting shaft assembly (7) is connected and fixed and gets stopper rod assembly (25), is arranged on the cillin bottle plug that cillin bottle gets below stopper rod assembly (25) and only stops assembly (26) with carrying.
3. pattern of fusion bottle placer as claimed in claim 2, it is characterized in that, described syringe nest plate center plate assemblies (2) or cillin bottle nest plate center plate assemblies (24) are fixed on x, on y twin shaft travelling car assembly (1) by two tightening knobs (3).
CN201610085941.9A 2016-02-15 2016-02-15 A kind of pattern of fusion bottle placer Active CN105565239B (en)

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CN105565239B CN105565239B (en) 2018-08-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106864791A (en) * 2017-04-21 2017-06-20 山东新华医疗器械股份有限公司 A kind of precharging type syringe train line bulking system
CN107364822A (en) * 2017-08-25 2017-11-21 原子高科股份有限公司 A kind of high-precision radioactivity decoction automatic subpackaging equipment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3424209A (en) * 1965-06-28 1969-01-28 Antoine Di Settembrini Device for handling objects on a conveyor
CN201634405U (en) * 2009-12-04 2010-11-17 顾志伟 Disposable injector filling and plugging machine
CN203794581U (en) * 2014-04-04 2014-08-27 上海都能制药机械设备有限公司 Vacuum box plugging device
CN104310295A (en) * 2014-09-28 2015-01-28 长沙一星制药机械有限公司 Disposable syringe filling and plugging machine
CN204938957U (en) * 2015-07-20 2016-01-06 上海华东制药机械有限公司 A kind of pre-encapsulated injector plug enclosuring structure

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3424209A (en) * 1965-06-28 1969-01-28 Antoine Di Settembrini Device for handling objects on a conveyor
CN201634405U (en) * 2009-12-04 2010-11-17 顾志伟 Disposable injector filling and plugging machine
CN203794581U (en) * 2014-04-04 2014-08-27 上海都能制药机械设备有限公司 Vacuum box plugging device
CN104310295A (en) * 2014-09-28 2015-01-28 长沙一星制药机械有限公司 Disposable syringe filling and plugging machine
CN204938957U (en) * 2015-07-20 2016-01-06 上海华东制药机械有限公司 A kind of pre-encapsulated injector plug enclosuring structure

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106864791A (en) * 2017-04-21 2017-06-20 山东新华医疗器械股份有限公司 A kind of precharging type syringe train line bulking system
CN107364822A (en) * 2017-08-25 2017-11-21 原子高科股份有限公司 A kind of high-precision radioactivity decoction automatic subpackaging equipment
CN107364822B (en) * 2017-08-25 2022-09-23 原子高科股份有限公司 Automatic sub-packaging equipment of high accuracy radioactive liquid medicine

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Address after: 201109 Building 4, No. 1509, Duhui Road, Minhang District, Shanghai

Patentee after: Dongfulong Technology Group Co.,Ltd.

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Patentee before: SHANGHAI TOFFLON SCIENCE AND TECHNOLOGY Co.,Ltd.

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