CN105561194A - Traditional Chinese medicine tablet for treating peripheral facial paralysis and preparation method thereof - Google Patents
Traditional Chinese medicine tablet for treating peripheral facial paralysis and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses a traditional Chinese medicine tablet for treating peripheral facial paralysis and a preparation method thereof. The traditional Chinese medicine tablet is prepared from, by weight, 5-10 parts of mint, 3-8 parts of ligusticum wallichii, 10-15 parts of radix angelicae, 20-30 parts of radices Chinese parsnip roots, 5-10 parts of hawthorn fruits, 5-15 parts of radix curcumae, 5-15 parts of liquorice, 5-9 parts of manis pentadactyla, 15-20 parts of caulis spatholobi and auxiliaries. The traditional Chinese medicine tablet has the functions of promoting blood and qi circulation and dispelling wind and removing obstruction in the meridians, has a remarkable effect on acial paralysis and is low in cost and wide in applicability.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicinal tablet for the treatment of peripheral facial paralysis and preparation method thereof.
Background technology
Peripheral facial paralysis is medically called facial neuritis, facial paralysis, is commonly called as " hanging skew wind ", " wapperijaw wind " etc., is a kind of commonly encountered diseases that is principal character with facial expression muscle group dyskinesia.Cause the reason of facial paralysis a lot, but modal be due to face be subject to cold and cool stimulation after cause the microcirculation disturbance of nervus facialis, cause nervus facialis ischemia, edema pressurized, so that facial nerve function disappearance, its facial expression myoparalysis controlled.Some patients thinks that facial paralysis is a kind of minor illness, can spontaneous recovery, does not have sequela again.If hardly realize that facial paralysis is without treatment, not only recover slow, but also the complication such as the related motion of facial spasm, facial muscle, facial muscle fibroid contracture can be caused, these complication compare stubborn problem in clinical treatment often, do not have specific way, a lot of patient is that disease accompanies it lifelong, so facial paralysis must in time, thoroughly.
China Patent No. CN102579852A discloses a kind of medicament for the treatment of peripheral facial paralysis, and this Chinese drugs agentia not by decocting, but is directly pulverized, and add the medicament that sucrose is made, this makes the drug effect of Chinese medicine have a greatly reduced quality, and reduces therapeutic effect.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of Chinese medicine of thorough treatment peripheral facial paralysis, drug effect is fast, and cost is low.
For realizing above object, the present invention is achieved by the following technical programs:
Treat a Chinese medicinal tablet for peripheral facial paralysis, be made up of the raw material of following weight portion: Herba Menthae 5-10 part, Rhizoma Chuanxiong 3-8 part, Radix Angelicae Dahuricae 10-15 part, Radix Saposhnikoviae 20-30 part, Fructus Crataegi 5-10 part, Radix Curcumae 5-15 part, Radix Glycyrrhizae 5-15 part, Squama Manis 5-9 part, Caulis Spatholobi 15-20 part, adjuvant.
Preferably, the Chinese medicinal tablet for the treatment of peripheral facial paralysis, is made up of the raw material of following weight portion: Herba Menthae 6 parts, Rhizoma Chuanxiong 7 parts, the Radix Angelicae Dahuricae 12 parts, Radix Saposhnikoviae 18 parts, Fructus Crataegi 6 parts, Radix Curcumae 10 parts, 10 parts, Radix Glycyrrhizae, Squama Manis 8 parts, Caulis Spatholobi 18 parts, adjuvant.
Preferably, described adjuvant comprises 50 parts, dextrin, carboxymethyl starch sodium 55 parts.
The preparation method of the Chinese medicinal tablet for the treatment of peripheral facial paralysis, comprises the following steps:
(1), after Herba Menthae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being washed, soak 2 hours;
(2), after Squama Manis first being boiled with big fire, turn little fire and decoct 1 hour, remove slag, obtain medicament 1;
(3), after the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being boiled with big fire, turn little fire and decoct after 30 minutes, remove slag, obtain medicament 2;
(4) by medicament 1 and medicament also 2-in-1, be dried to dry cream;
(5) Rhizoma Chuanxiong and Herba Menthae wear into 200 object powder respectively;
(6) after being mixed homogeneously with Rhizoma Chuanxiong power, Herba Menthae powder by the dry cream in step (4), then add dextrin, carboxymethyl starch sodium mix homogeneously, obtain Chinese medicine mastic, river Chinese medicinal ointment soma is dry, tabletting, obtain Chinese medicinal tablet.
Preferably, it is 3%-5% that described Chinese medicinal ointment body is dried to water content.
Preferably, the quality of described Chinese medicinal tablet is 2g/ sheet, and wherein Chinese medicine quality is about 0.25g/ sheet.
To treatment facial hemiparalysis, eyelid, beneficial effect of the present invention: in the present invention, Herba Menthae has the effect of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, occurs that the symptoms such as dysraphism are very helpful; Rhizoma Chuanxiong is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the suitable various disease of stagnation of blood stasis; The Radix Angelicae Dahuricae has the effect of the dehumidifying that gets rid of illness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain; Radix Saposhnikoviae has expelling pathogenic wind from the body surface, effect of relieving convulsion, has significant effect to facial paralysis; Fructus Crataegi can circulation of qi promoting dissipating blood stasis; Radix Curcumae can promoting blood circulation and stopping pain, promoting QI circulation for relieving depression; The bitterness of Radix Glycyrrhizae scalable Radix Curcumae and cold; Squama Manis has excellent eliminating mass of invigorating blood circulation, the effect of expel wind to dredge collateral; Caulis Spatholobi has blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of relaxing muscles and tendons and activating QI and blood in the collateral.Chinese medicine preparation of the present invention has blood-activating and qi-promoting, the effect of dispelling wind and removing obstruction in the collateral, and can have significant effect to facial paralysis, and the cost of Chinese medicine preparation is low, the suitability is wide.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1:
For realizing above object, the present invention is achieved by the following technical programs:
Treat a Chinese medicinal tablet for peripheral facial paralysis, be made up of the raw material of following weight portion: Herba Menthae 5 parts, Rhizoma Chuanxiong 8 parts, the Radix Angelicae Dahuricae 15 parts, Radix Saposhnikoviae 25 parts, Fructus Crataegi 5 parts, Radix Curcumae 10 parts, 10 parts, Radix Glycyrrhizae, Squama Manis 9 parts, Caulis Spatholobi 20 parts, 50 parts, dextrin, carboxymethyl starch receive 55 parts.
The preparation method of the Chinese medicinal tablet for the treatment of peripheral facial paralysis, comprises the following steps:
(1), after Herba Menthae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being washed, soak 2 hours;
(2), after Squama Manis first being boiled with big fire, turn little fire and decoct 1 hour, remove slag, obtain medicament 1;
(3), after the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being boiled with big fire, turn little fire and decoct after 30 minutes, remove slag, obtain medicament 2;
(4) by medicament 1 and medicament also 2-in-1, be dried to paste;
(5) Rhizoma Chuanxiong and Herba Menthae wear into 200 object powder respectively;
(6) after being mixed homogeneously with Rhizoma Chuanxiong power, Herba Menthae powder by the paste Chinese medicine in step (4), then add dextrin and carboxymethyl starch and receive mix homogeneously, being dried to water content is 3%-5%, and tabletting after dry, obtains Chinese medicinal tablet.
The using method of Chinese medicinal tablet: each 3, every day three times 10 days is a course for the treatment of.
Clinical case: Lee XX, man, 50 years old, slobbering before treatment, facial hemiparalysis, the symptoms such as facial expression is strange, stiff, after taking 2 courses for the treatment of of this medicament, transference cure, mouth eye was rectified, and nasolabial fold is symmetrical, and frown, close order etc. and recover normal, face nerve rejuvenates.
Embodiment 2:
Treat a Chinese medicinal tablet for peripheral facial paralysis, be made up of the raw material of following weight portion: Herba Menthae 10 parts, Rhizoma Chuanxiong 3 parts, the Radix Angelicae Dahuricae 10 parts, Radix Saposhnikoviae 20 parts, Fructus Crataegi 6 parts, Radix Curcumae 5 parts, 5 parts, Radix Glycyrrhizae, Squama Manis 5 parts, Caulis Spatholobi 15 parts, 50 parts, dextrin, carboxymethyl starch receive 55 parts.
The preparation method of the Chinese medicinal tablet of described treatment peripheral facial paralysis, with embodiment 1.
Clinical case: Korea Spro X, man 25 years old, the facial paralysis that otitis media causes, it is asymmetric that clinical symptoms shows as bilateral motion of twinkling, and when speaking, face lower jaw is crooked, and after taking 2 courses for the treatment of of this medicament, transference cure, facial hemiparalysis symptom is eliminated and return, without recurrence.
Embodiment 3:
Treat a Chinese medicinal tablet for peripheral facial paralysis, be made up of the raw material of following weight portion: Herba Menthae 8 parts, Rhizoma Chuanxiong 5 parts, the Radix Angelicae Dahuricae 12 parts, Radix Saposhnikoviae 30 parts, Fructus Crataegi 8 parts, Radix Curcumae 15 parts, 15 parts, Radix Glycyrrhizae, Squama Manis 6 parts, Caulis Spatholobi 16 parts, 50 parts, dextrin, carboxymethyl starch 55 parts.
The preparation method of the Chinese medicinal tablet of described treatment peripheral facial paralysis, with embodiment 1.
Clinical case: XX, female, 55 years old, suffers from facial paralysis 1 year, occurs " wapperijaw " symptom after wind-engaging, and face's mouth wheel is pricked flesh and often knotted, and after taking 4 courses for the treatment of of this medicament, face no longer knots, but when laughing, bicker is slightly crooked, and symptom alleviates.
Embodiment 4
Treat a Chinese medicinal tablet for peripheral facial paralysis, be made up of the raw material of following weight portion: Herba Menthae 6 parts, Rhizoma Chuanxiong 7 parts, the Radix Angelicae Dahuricae 12 parts, Radix Saposhnikoviae 28 parts, Fructus Crataegi 6 parts, Radix Curcumae 10 parts, 10 parts, Radix Glycyrrhizae, Squama Manis 8 parts, Caulis Spatholobi 18 parts, paste 50 parts, carboxymethyl starch receive 55 parts.
The preparation method of the Chinese medicinal tablet of described treatment peripheral facial paralysis, with embodiment 1.
Clinical case: Korea Spro XX, female, 60 years old, suffer from facial paralysis 3 years, uncontrollable facial expression, right eye angle was sagging, and face is seriously crooked, and after taking 4 courses for the treatment of of this medicament, the crooked symptom of face improves, and face nerve part is recovered, and symptom alleviates.
Invention Chinese herbal and crude drugs preparations is used for clinical treatment facial paralysis patient 138 example, cure rate reaches 80%, and does not occur recurrence after curing.
To sum up, the embodiment of the present invention has following beneficial effect: Chinese medicine preparation of the present invention has blood-activating and qi-promoting, the effect of dispelling wind and removing obstruction in the collateral, and can have significant effect to facial paralysis, and the cost of Chinese medicine preparation is low, the suitability is wide.
It should be noted that, in this article, the such as relational terms of first and second grades and so on is only used for an entity or operation to separate with another entity or operating space, and not necessarily requires or imply the relation that there is any this reality between these entities or operation or sequentially.And, term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thus make to comprise the process of a series of key element, method, article or equipment and not only comprise those key elements, but also comprise other key elements clearly do not listed, or also comprise by the intrinsic key element of this process, method, article or equipment.When not more restrictions, the key element limited by statement " comprising ... ", and be not precluded within process, method, article or the equipment comprising described key element and also there is other identical element.
Above embodiment only in order to technical scheme of the present invention to be described, is not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (6)
1. treat the Chinese medicinal tablet of peripheral facial paralysis for one kind, it is characterized in that, be made up of the raw material of following weight portion: Herba Menthae 5-10 part, Rhizoma Chuanxiong 3-8 part, Radix Angelicae Dahuricae 10-15 part, Radix Saposhnikoviae 20-30 part, Fructus Crataegi 5-10 part, Radix Curcumae 5-15 part, Radix Glycyrrhizae 5-15 part, Squama Manis 5-9 part, Caulis Spatholobi 15-20 part, adjuvant.
2. the Chinese medicinal tablet for the treatment of peripheral facial paralysis as claimed in claim 1, it is characterized in that, be made up of the raw material of following weight portion: Herba Menthae 6 parts, Rhizoma Chuanxiong 7 parts, the Radix Angelicae Dahuricae 12 parts, Radix Saposhnikoviae 18 parts, Fructus Crataegi 6 parts, Radix Curcumae 10 parts, 10 parts, Radix Glycyrrhizae, Squama Manis 8 parts, Caulis Spatholobi 18 parts, adjuvant.
3. the Chinese medicinal tablet for the treatment of peripheral facial paralysis as claimed in claim 2, it is characterized in that, described adjuvant comprises 50 parts, dextrin, carboxymethyl starch sodium 55 parts.
4. a preparation method for the Chinese medicinal tablet for the treatment of peripheral facial paralysis as claimed in claim 1 or 2, is characterized in that, comprise the following steps:
(1), after Herba Menthae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being washed, soak 2 hours;
(2), after Squama Manis first being boiled with big fire, turn little fire and decoct 1 hour, remove slag, obtain medicament 1;
(3), after the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Fructus Crataegi, Radix Curcumae, Radix Glycyrrhizae, Squama Manis, Caulis Spatholobi being boiled with big fire, turn little fire and decoct after 30 minutes, remove slag, obtain medicament 2;
(4) by medicament 1 and medicament also 2-in-1, be dried to dry cream;
(5) Rhizoma Chuanxiong and Herba Menthae wear into 200 object powder respectively;
(6) after being mixed homogeneously with Rhizoma Chuanxiong power, Herba Menthae powder by the dry cream in step (4), then add dextrin, carboxymethyl starch sodium, mix homogeneously obtains Chinese medicine mastic, by dry for Chinese medicinal ointment soma, tabletting, obtains Chinese medicinal tablet.
5. the preparation method of the Chinese medicinal tablet for the treatment of peripheral facial paralysis as claimed in claim 4, it is characterized in that, it is 3%-5% that described Chinese medicinal ointment body is dried to water content.
6. the preparation method of the Chinese medicinal tablet for the treatment of peripheral facial paralysis as claimed in claim 4, it is characterized in that, the quality of described Chinese medicinal tablet is 2g/ sheet, and wherein Chinese medicine quality is about 0.25g/ sheet.
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| CN104173456A (en) * | 2013-05-24 | 2014-12-03 | 上海市长宁区天山中医医院 | Traditional Chinese medicine composition treating facial neuritis, preparation method and application thereof |
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| CN104173456A (en) * | 2013-05-24 | 2014-12-03 | 上海市长宁区天山中医医院 | Traditional Chinese medicine composition treating facial neuritis, preparation method and application thereof |
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Application publication date: 20160511 |