CN105560686A - Chinese herbal medicine formula for inhibiting aeromonas sobria - Google Patents
Chinese herbal medicine formula for inhibiting aeromonas sobria Download PDFInfo
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- CN105560686A CN105560686A CN201410549616.4A CN201410549616A CN105560686A CN 105560686 A CN105560686 A CN 105560686A CN 201410549616 A CN201410549616 A CN 201410549616A CN 105560686 A CN105560686 A CN 105560686A
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Abstract
The invention discloses a Chinese herbal medicine formula for inhibiting aeromonas sobria. The Chinese herbal medicine formula for inhibiting the aeromonas sobria is characterized by including at least one of acacia catechu, gallnuts, fructus schisandrae, dark plums, pomegranate rind, dried alum, viola, radix clematidis, radix sanguisorbae, flos caryophylli, coptis chinensis, common carpesium fruits, herba siegesbeckiae, folium artemisiae argyi, perillaseed, a humifuse euphorbia herb, giant knotweeds, radix rhapontici seeds, cassia seeds, prunella vulgaris, radix isatidis, angelica roots, a small centipede herb, white paeony roots, myrrh, magnolia barks, aster, common cnidium fruits, wild chrysanthemum flowers, Chinese rhubarb, forsythia, a spreading hedyotis herb, raspberries, Chinese bulbul, betel nuts, evodia rutaecarpa, Gentiana scabra Bunge, pawpaw, raw rhizoma atractylodis, folium isatidis, houttuynia cordata, peony tree root barks and sapium sebiferum, wherein the formula formed by the acacia catechu, the gallnut, the fructus schisandrae and the dark plums which are mixed according to the mass ratio of 2:4:1:22 has the best bacteriostatic effect. The Chinese herbal medicine formula has the advantages that the Chinese herbal medicine formula is natural, non-toxic and free of residues, does not produce drug resistance and is low in cost.
Description
Technical field
The present invention relates to a kind of Chinese herbal medicine formula, especially relate to a kind of Chinese herbal medicine formula suppressing Aeromonas sobria.
Background technology
Aeromonas sobria, as another common pathogenic kind of Aeromonas, is distributed widely in various fresh water, is one of hydrobiological principal causative cause of disease.It can endanger nearly all freshwater fish, batrachia, Trionyx sinensis Wiegmann even birds and mammal, causes the disease that septicemia, diarrhoea etc. are cardinal symptom.Aeromonas sobria has extremely strong pathogenicity to Fish, can invade healthy fish body, and make quick death after fish body visceral hemorrhage, Aeromonas sobria can also cause the skin ulceration of Cyprinus carpio.Aeromonas sobria is one of modal pathogenic bacterium in China aquaculture fresh-water fishes, also be one of modal pathogenic bacterium in the crowd of China's Coastal Areas, because Aeromonas sobria can by the digestive tract infection people of ill fish, so after the mankind eat the fish after infecting Aeromonas sobria, there will be the disease of the serious threat human healths such as diarrhoea, septicemia.
At present chemical drugs, antibiotic or deactivation, inactivated vaccine are mainly utilized to the control of Aeromonas sobria, wherein main to throw in feeding antibiotic for Main Means.But long-term Drug abuse or antibiotic can cause water environment pollution, thus cause breeding environment to worsen, disturbed ecological balance, and antibacterial also can produce drug resistance, and drug residue also forms potential threat to eater.
Summary of the invention
Technical problem to be solved by this invention is to provide one and bacterial drug resistance, toxin not only can be avoided to accumulate and environmental pollution, and can reduce the Chinese herbal medicine formula of suppression Aeromonas sobria of production cost.
The technical scheme that the present invention solves the problems of the technologies described above institute Bian is:
A kind of Chinese herbal medicine formula suppressing Aeromonas sobria, comprise catechu, Galla Chinensis, Fructus Schisandrae Chinensis, Fructus Mume, Pericarpium Granati, dried Alumen, Herba Violae, Radix Clematidis, Radix Sanguisorbae, Flos Caryophylli, Rhizoma Coptidis, Fructus Carpesii, Herba Siegesbeckiae, Folium Artemisiae Argyi, Fructus Perillae, Herba Euphorbiae Humifusae, Rhizoma Polygoni Cuspidati, Radix Rhapontici, Semen Cassiae, Spica Prunellae, Radix Isatidis, the Radix Angelicae Dahuricae, sandwort, the Radix Paeoniae Alba, Myrrha (processed), Cortex Magnoliae Officinalis, Radix Asteris, Fructus Cnidii, Flos Chrysanthemi Indici, Radix Et Rhizoma Rhei, Fructus Forsythiae, Herba Hedyotidis Diffusae, Fructus Rubi, the Radix Pulsatillae, Semen Arecae, Fructus Evodiae, Radix Gentianae, Fructus Chaenomelis, atractylodes rhizome, Folium Isatidis, Herba Houttuyniae, at least one in Cortex Moutan and Cortex Sapii Radicis.
This Chinese herbal medicine is made up of following raw material and weight ratio: catechu, Galla Chinensis, Fructus Schisandrae Chinensis and Fructus Mume mix with the ratio of 2:4:1:2.The antibacterial medicament of this formula composition, fungistatic effect is best, and its minimal inhibitory concentration MIC is 2.93mg/ml
0compared with prior art, the invention has the advantages that: a kind of Chinese herbal medicine formula suppressing Aeromonas sobria of the present invention, Bian herbal control fish diseases, advantages such as bacterial drug resistance, toxin not only can being avoided to accumulate and the problem such as environmental pollution, and production cost can be reduced, there is natural, nontoxic residue-free, not produce drug resistance, be cheap, toxic and side effects can not be caused to humans and animals, and manufacturing process is simple, easily operates, is easy to realize factorial praluction.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
Embodiment 1
A kind of Chinese herbal medicine formula suppressing Aeromonas sobria of the present invention, following 43 kinds of Chinese herbal medicine are to the equal tool of Aeromonas sobria bacteriostasis in various degree.
First, the youngster bitter edible plant and Galla Chinensis etc. are the strongest to the bacteriostasis of Aeromonas sobria, and its MIC is 6.25mg/ml; Fructus Schisandrae Chinensis, Fructus Mume and Pericarpium Granati etc. are also very strong to Aeromonas sobria inhibitory action, and its MIC is 12.5mg/ml.Secondly, dried Alumen, Herba Violae Radix Clematidis, Radix Sanguisorbae, Flos Caryophylli and Rhizoma Coptidis etc. all have stronger inhibitory action to Aeromonas sobria, and its MIC is 25mg/ml.Again, Fructus Carpesii, Herba Siegesbeckiae, Folium Artemisiae Argyi, Fructus Perillae, Herba Euphorbiae Humifusae, Rhizoma Polygoni Cuspidati, Radix Rhapontici, Semen Cassiae, Spica Prunellae, Radix Isatidis, the Radix Angelicae Dahuricae, sandwort, the Radix Paeoniae Alba, Myrrha (processed), Cortex Magnoliae Officinalis, Radix Asteris, Fructus Cnidii, Flos Chrysanthemi Indici, Radix Et Rhizoma Rhei, Fructus Forsythiae, Herba Hedyotidis Diffusae, Fructus Rubi, the Radix Pulsatillae, bulky, Fructus Evodiae, Radix Gentianae, Fructus Chaenomelis, atractylodes rhizome, Folium Isatidis, Herba Houttuyniae, Cortex Moutan and Cortex Sapii Radicis are slightly weak to the inhibitory action of Aeromonas sobria, and its MIC is 100mg/ml.Therefore, at least one in optional said herbal medicine is as the suppression medicament of Aeromonas sobria, and the strong youngster bitter edible plant of bacteriostasis, Galla Chinensis, Fructus Schisandrae Chinensis, Fructus Mume and Pericarpium Granati etc. can be used as the first-selected antibacterial medicines of control Aeromonas sobria.
Embodiment 2
A kind of Chinese herbal medicine formula suppressing Aeromonas sobria of the present invention, this Chinese herbal medicine is made up of following raw material and weight ratio: the youngster bitter edible plant, Galla Chinensis, Fructus Schisandrae Chinensis and Fructus Mume mix with the ratio of 2:4:1:2.Result shows, this formula has significant fungistatic effect to Aeromonas sobria, all obvious than the fungistatic effect of single medicinal material and other Chinese herbal medicine compound prescription combined, its minimal inhibitory concentration MIC is that the minimal inhibitory concentration MIC of the Chinese herbal medicine compound prescription that the 2.mg/ml bitter edible plant, Galla Chinensis, Fructus Schisandrae Chinensis and Fructus Mume mix with the ratio of 1:1:1:1 is for 12.5mg/ml, the minimal inhibitory concentration MIC of the Chinese herbal medicine compound prescription that the youngster bitter edible plant, Galla Chinensis, Fructus Schisandrae Chinensis and Fructus Mume mix with the ratio of 2:2:1:8, for 20.31mg/ml, does not all have the good antimicrobial effect of optimum formula.
Embodiment 3
Chinese herbal medicine is to the extracorporeal bacteria inhibitor test of Aeromonas sobria
Chinese herbal medicine selection and medicinal liquid preparation thereof
86 kinds of Chinese herbal medicine that this research is chosen are all purchased from Beijing, Ningbo City pharmacy of Tongrentang.These 86 kinds of Chinese herbal medicine are respectively: Radix Sanguisorbae, Pericarpium Granati, dried Alumen, the Fructus Kochiae, Fructus Carpesii, Herba Siegesbeckiae, Herba Lobeliae Chinensis, Folium Artemisiae Argyi, Fructus Perillae, Herba Andrographis, Herba Euphorbiae Humifusae, Rhizoma Osmundae, giant knotweed rhizome tablet, Herba Duchesneae Indicae grass, Fructus Quisqualis, Radix Rhapontici, Semen Cassiae, sophora film, yellow Chinese tallow tree, Folium Mahoniae, Herba Senecionis Scandentis, Herba Taraxaci, Herba Polygoni Avicularis, Caulis Perillae, Herba Artemisiae Annuae, Herba Violae, Herba Eupatorii, Herba Artemisiae Scopariae, Spica Prunellae, Rhizoma Acori Graminei, Radix Isatidis, Semen Torreyae, (life) Radix Polygoni Multiflori, the Radix Angelicae Dahuricae, Semen Ginkgo, Semen Raphani, terminalia flesh, Fructus Perillae, Radix Clematidis, Radix Curcumae, I does not eat by bird, Bai Qiao, the Radix Stemonae, scorching Myrrha, Herba Solani Nigri, Cortex Magnoliae Officinalis, Radix Asteris, the youngster bitter edible plant, Rhizoma Arisaematis, Galla Chinensis, the Radix Astragali, Fructus Cnidii, Flos Chrysanthemi Indici, Radix Et Rhizoma Rhei (raw army), the Rhizoma Anemarrhenae, Cortex Dictamni, Radix Glycyrrhizae, Herba Portulacae, Flos Lonicerae, Fructus Forsythiae, Herba Verbenae, Herba Hedyotidis Diffusae, (north) Radix Bupleuri, Fructus Schisandrae Chinensis, Fructus Rubi, the Radix Pulsatillae, Semen Arecae, the Radix Linderae, Fructus Evodiae, Radix Gentianae, Fructus Chaenomelis, (life) Rhizoma Atractylodis, Radix Scutellariae, Aloe, Fructus Mume, Folium Isatidis, Herba Houttuyniae, Cortex Moutan, Semen Pharbitidis, Fructus Arctii, Herba Plantaginis, Rhizoma Paridis, Flos Caryophylli, Rhizoma Coptidis, (life) Rhizoma Curcumae, Cortex Sapii Radicis.
Claims (2)
1. one kind is suppressed the Chinese herbal medicine formula of Aeromonas sobria, it is characterized in that: comprise the youngster bitter edible plant, Galla Chinensis, Fructus Schisandrae Chinensis, Fructus Mume, Pericarpium Granati, dried Alumen, Herba Violae, Radix Clematidis, Radix Sanguisorbae, Flos Caryophylli, Rhizoma Coptidis, Fructus Carpesii, Herba Siegesbeckiae, Folium Artemisiae Argyi, Fructus Perillae, Herba Euphorbiae Humifusae, Rhizoma Polygoni Cuspidati, Radix Rhapontici, Semen Cassiae, Spica Prunellae, Radix Isatidis, the Radix Angelicae Dahuricae, sandwort, the Radix Paeoniae Alba, Myrrha (processed), Cortex Magnoliae Officinalis, Radix Asteris, Fructus Cnidii, Flos Chrysanthemi Indici, Radix Et Rhizoma Rhei, Fructus Forsythiae, Herba Hedyotidis Diffusae, Fructus Rubi, the Radix Pulsatillae, Semen Arecae, Fructus Evodiae, Radix Gentianae, Fructus Chaenomelis, atractylodes rhizome, Folium Isatidis, Herba Houttuyniae, at least one in Cortex Moutan and Cortex Sapii Radicis.
2., according to a kind of Chinese herbal medicine formula suppressing Aeromonas sobria in claim 1, it is characterized in that: this Chinese herbal medicine is made up of following raw material and weight ratio: the youngster bitter edible plant, Galla Chinensis, Fructus Schisandrae Chinensis and Fructus Mume mix with the ratio of 2:4:1:2.
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Cited By (1)
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CN112602664A (en) * | 2020-12-10 | 2021-04-06 | 贵州铜仁厚聚农业科技开发服务有限公司 | Breeding method for improving disease resistance of live pigs |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112602664A (en) * | 2020-12-10 | 2021-04-06 | 贵州铜仁厚聚农业科技开发服务有限公司 | Breeding method for improving disease resistance of live pigs |
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