CN105510608A - Automatic biochip reading equipment - Google Patents
Automatic biochip reading equipment Download PDFInfo
- Publication number
- CN105510608A CN105510608A CN201510833175.5A CN201510833175A CN105510608A CN 105510608 A CN105510608 A CN 105510608A CN 201510833175 A CN201510833175 A CN 201510833175A CN 105510608 A CN105510608 A CN 105510608A
- Authority
- CN
- China
- Prior art keywords
- carrying apparatus
- water jet
- nozzle boss
- lotion pipeline
- full
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/02—Cleaning by the force of jets or sprays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
- G01N2035/00841—Identification of carriers, materials or components in automatic analysers nature of coded information results of the analyses
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses automatic biochip reading equipment. The automatic biochip reading equipment comprises a casing, a loading device used for loading a biochip and arranged in the casing, a collection apparatus used for collecting an image, shading apparatuses, a control apparatus used for controlling operation of the automatic biochip reading equipment, and a chip cleaning device. The loading device comprises a detection card which is placed on the loading device, spacing strips are arranged at two sides of the loading device, the detection card is just inserted in the spacing strips at two sides; the shading apparatuses are arranged at two sides of the loading device, the collection apparatus is erected on the shading apparatus; the collection apparatus comprises a CCD camera, an objective lens connected with a photosensitive port of the CCD camera, and a camera power connected with the CCD camera, and the objective lens faces to the loading device. Compared with prior art, the automatic biochip reading equipment has the characteristics of compact structure, saved space and convenient usage.
Description
Technical field
The present invention relates to a kind of full-automatic biological chips fetch equipment.
Background technology
Biological chip testing technology, fluorescence, biotin or additive method is adopted to mark biomolecule (as DNA, RNA, protein molecular, antigen, the antibody etc.) target be fixed on bio-chip substrate, and marking signal is changed into the view data that can supply analyzing and processing by building some special pick-up units, to obtain and to analyze the various information such as biology, physics, chemistry of the biomolecule on biochip, the time of day of diagnostic biomolecule.
Biochip test equipment is widely used in the fields such as scientific research, medicine, health, for catching and processing the instrument of biochip image, traditional biochip supplies analysis has the following disadvantages: (1) checkout equipment is generally divided into multiple chamber by dividing plate, make the volume of checkout equipment larger, structure is comparatively complicated, dismounting is inconvenient, is not easy to use.(2) biochip needs are fixed after aliging with object lens again, and manual shift position is inaccurate.(3) in detecting, due to higher to the requirement for horizontality of biochip, then biochip slightly offset level position time, the easily accuracy of impact observation image.(4) there is not chip cleaning function in checkout equipment.
Summary of the invention
The invention provides a kind of full-automatic biological chips fetch equipment, comprise housing, be located in housing for carry biochip carrying apparatus, for gather image harvester, with shade, for controlling control device, device for cleaning chip that a kind of full-automatic biological chips fetch equipment operates, described carrying apparatus comprises the test card be positioned on this carrying apparatus, these carrying apparatus both sides are provided with positive stop strip, and described test card be able to be inserted in the positive stop strip of both sides; Described shade is for being installed on this carrying apparatus both sides, described harvester is set up on this shade, and this harvester comprises CCD camera, is connected to the object lens of the photosensitive port of this CCD camera, and the camera power supply to be connected with this CCD camera, described object lens are right against carrying apparatus; Device for cleaning chip is by pedestal, the first lotion pipeline, the second lotion pipeline, rinse bath, wastewater outlet, described first lotion pipeline, the second lotion pipeline are arranged on pedestal, the first nozzle boss and the second nozzle boss is provided with in described rinse bath, the first described lotion pipeline is communicated with liquid first nozzle boss, the second described lotion pipeline is communicated with the second nozzle boss, described first nozzle boss and the second nozzle boss are respectively equipped with the first water jet and the second water jet, and described wastewater outlet is arranged on the below of rinse bath.Control device is connected with a power interface and a power switch, and described control device is provided with a communication interface.Housing forms by lower house with upper shell, and described carrying apparatus is located at the side in housing, the side body be connected offers a test card insert port with this carrying apparatus.First water jet and the second water jet are respectively equipped with 1 ~ 10 rinse liquid outlet, wiper mechanism is provided with chip handgrip, chip handgrip is used for grab chips and is placed in by chip between two water jets, is convenient to rinse, and the distance between the first water jet and the second water jet is adjustable.
It is complicated that the object of the invention is to solve conventional bio-chip assay device structures, and volume is comparatively large, uses comparatively inconvenience, also can not damage material to be detected on chip while fully being cleaned up by the residuals on chip.
Accompanying drawing explanation
Fig. 1 is that inner structure of the present invention overlooks direction schematic diagram.
Fig. 2 is device for cleaning chip schematic diagram of the present invention.
In Fig. 1,10 be housing, 12 be carrying apparatus, 120 be positive stop strip, 121 be test card, 13 be shade, 15 be control device, 150 be power interface, 151 be power switch, 16 be harvester, 160 be communication interface, 111 for device for cleaning chip.
In Fig. 2,1 is rinse bath, 5 is biochip for wastewater outlet, 6 be the first nozzle boss, 7 be the second nozzle boss, 8 be the first water jet, 9 is the second water jet, 10,11 is chip handgrip for pedestal, 2 to be the first lotion pipeline, 3 be the second lotion pipeline, 4.
Embodiment
Below in conjunction with the drawings and specific embodiments, the invention will be further described:
A kind of full-automatic biological chips fetch equipment, comprise housing 10, be located in housing for carry biochip carrying apparatus 12, for gather image harvester 16, with shade 13, for controlling control device 15, device for cleaning chip 111 that a kind of full-automatic biological chips fetch equipment operates, described carrying apparatus 12 comprises the test card 121 be positioned on this carrying apparatus, these carrying apparatus both sides are provided with positive stop strip 120, and described test card 121 be able to be inserted in the positive stop strip 120 of both sides; Described shade 13 is for being installed on this carrying apparatus 12 both sides, described harvester 16 is set up on this shade 13, this harvester 16 comprises CCD camera, be connected to the object lens of the photosensitive port of this CCD camera, and the camera power supply to be connected with this CCD camera, described object lens are right against carrying apparatus; Device for cleaning chip is by pedestal 1, first lotion pipeline 2, second lotion pipeline 3, rinse bath 4, wastewater outlet 5, described first lotion pipeline 2, second lotion pipeline 3 is arranged on pedestal 1, the first nozzle boss 6 and the second nozzle boss 7 is provided with in described rinse bath, the first described lotion pipeline 2 is communicated with liquid first nozzle boss 6, the second described lotion pipeline 3 is communicated with the second nozzle boss 7, described first nozzle boss 6 and the second nozzle boss 7 are respectively equipped with the first water jet 8 and the second water jet 9, and described wastewater outlet 5 is arranged on the below of rinse bath 4; Described control device 15 is connected with power interface 150 and a power switch 151, and described control device 15 is provided with a communication interface 160; Described housing 10 forms by lower house with upper shell, described carrying apparatus 12 is located at the side in housing, the side body be connected with this carrying apparatus offers a test card insert port, the first described water jet 8 and the second water jet 9 are respectively equipped with 1 ~ 10 rinse liquid outlet, the distance that described wiper mechanism is provided with between chip handgrip 11, first water jet 8 and the second water jet 9 is adjustable.
During use, utilize chip handgrip 11 grab chips, chip is placed between two water jets, chip cleaning fluid is flowed into the first nozzle boss 6 and the second nozzle boss 7 respectively by the first lotion pipeline 2 and the second lotion pipeline 3, then cleaning fluid is from the first water jet 8 and the ejection of the second water jet 9, cleans biochip.
Claims (4)
1. a full-automatic biological chips fetch equipment, comprise housing, be located in housing for carry biochip carrying apparatus, for gather image harvester, with shade, for controlling control device, device for cleaning chip that a kind of full-automatic biological chips fetch equipment operates, it is characterized in that: described carrying apparatus comprises the test card be positioned on this carrying apparatus, these carrying apparatus both sides are provided with positive stop strip, and described test card be able to be inserted in the positive stop strip of both sides; Described shade is for being installed on this carrying apparatus both sides, described harvester is set up on this shade, and this harvester comprises CCD camera, is connected to the object lens of the photosensitive port of this CCD camera, and the camera power supply to be connected with this CCD camera, described object lens are right against carrying apparatus; Device for cleaning chip is by pedestal, the first lotion pipeline, the second lotion pipeline, rinse bath, wastewater outlet, described first lotion pipeline, the second lotion pipeline are arranged on pedestal, the first nozzle boss and the second nozzle boss is provided with in described rinse bath, the first described lotion pipeline is communicated with liquid first nozzle boss, the second described lotion pipeline is communicated with the second nozzle boss, described first nozzle boss and the second nozzle boss are respectively equipped with the first water jet and the second water jet, and described wastewater outlet is arranged on the below of rinse bath; Described control device is connected with a power interface and a power switch, and described control device is provided with a communication interface; Described housing forms by lower house with upper shell, and described carrying apparatus is located at the side in housing, the side body be connected offers a test card insert port with this carrying apparatus.
2. a kind of full-automatic biological chips fetch equipment according to claim 1, is characterized in that, the first described water jet and the second water jet are respectively equipped with 1 ~ 10 rinse liquid outlet.
3. a kind of full-automatic biological chips fetch equipment according to claim 1, it is characterized in that, described wiper mechanism is provided with chip handgrip.
4. a kind of full-automatic biological chips fetch equipment according to claim 1, is characterized in that, the distance between the first water jet and the second water jet is adjustable.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510833175.5A CN105510608A (en) | 2015-11-25 | 2015-11-25 | Automatic biochip reading equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510833175.5A CN105510608A (en) | 2015-11-25 | 2015-11-25 | Automatic biochip reading equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105510608A true CN105510608A (en) | 2016-04-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510833175.5A Pending CN105510608A (en) | 2015-11-25 | 2015-11-25 | Automatic biochip reading equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105510608A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106770290A (en) * | 2016-12-16 | 2017-05-31 | 天津岳达科技有限公司 | A kind of biochip test cleaning device |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656724B1 (en) * | 1997-11-19 | 2003-12-02 | Mwg-Biotech Ag | Apparatus for automatic implementation of chemical or biological methods |
| CN2816811Y (en) * | 2005-02-24 | 2006-09-13 | 穆海东 | Biological chip detecting instrument |
| CN101696971A (en) * | 2009-10-19 | 2010-04-21 | 深港产学研基地 | Biochip analyzer and control system thereof |
| CN102814294A (en) * | 2012-06-19 | 2012-12-12 | 江苏三联生物工程有限公司 | Cleaning and drying device for biological chip |
| CN103954782A (en) * | 2014-04-11 | 2014-07-30 | 珠海美路得企业发展有限公司 | Biological chip detecting system |
| CN104198468A (en) * | 2014-08-05 | 2014-12-10 | 曲阜裕隆生物科技有限公司 | Biochip detector |
| CN204422530U (en) * | 2015-03-11 | 2015-06-24 | 厦门拜尔杰生物科技有限公司 | Biological chip reading apparatus |
-
2015
- 2015-11-25 CN CN201510833175.5A patent/CN105510608A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656724B1 (en) * | 1997-11-19 | 2003-12-02 | Mwg-Biotech Ag | Apparatus for automatic implementation of chemical or biological methods |
| CN2816811Y (en) * | 2005-02-24 | 2006-09-13 | 穆海东 | Biological chip detecting instrument |
| CN101696971A (en) * | 2009-10-19 | 2010-04-21 | 深港产学研基地 | Biochip analyzer and control system thereof |
| CN102814294A (en) * | 2012-06-19 | 2012-12-12 | 江苏三联生物工程有限公司 | Cleaning and drying device for biological chip |
| CN103954782A (en) * | 2014-04-11 | 2014-07-30 | 珠海美路得企业发展有限公司 | Biological chip detecting system |
| CN104198468A (en) * | 2014-08-05 | 2014-12-10 | 曲阜裕隆生物科技有限公司 | Biochip detector |
| CN204422530U (en) * | 2015-03-11 | 2015-06-24 | 厦门拜尔杰生物科技有限公司 | Biological chip reading apparatus |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106770290A (en) * | 2016-12-16 | 2017-05-31 | 天津岳达科技有限公司 | A kind of biochip test cleaning device |
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| PB01 | Publication | ||
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Application publication date: 20160420 |