CN105496873A - Mouthwash used during orthodontic treatment - Google Patents
Mouthwash used during orthodontic treatment Download PDFInfo
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- CN105496873A CN105496873A CN201510990320.0A CN201510990320A CN105496873A CN 105496873 A CN105496873 A CN 105496873A CN 201510990320 A CN201510990320 A CN 201510990320A CN 105496873 A CN105496873 A CN 105496873A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention belongs to the technical field of traditional Chinese medicine and particularly relates to mouthwash used during orthodontic treatment. The mouthwash is prepared from, by weight, 15-18 parts of aloes, 15-18 parts of green tea, 10-15 parts of cortex erythrinae, 3-8 parts of shinyleaf pricklyash roots, 1-3 parts of surfactant, 1-5 parts of sodium chloride and 100 parts of deionized water. The aloes are used for sterilization and inflammation prevention. The green tea is used for sterilization and bacterium inhibition. Cortex erythrinae is used for inhibiting ulcers. The shinyleaf pricklyash roots are used for detoxification and detumescence. The mouthwash can be used for cleaning the oral cavity, has the tooth-decay-prevention, hemostatic and antiphlogistic effects, improves the oral environment during orthodontic treatment of the oral cavity, and reduces the probability of oral complications.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, the collutory particularly used during a kind of orthodontic rectification.
Background technology
During Tooth orthodontic correction, usual tooth compares and is not easy to clean, and is easy to food debris to be trapped in around bracket, causes periodontitis, tooth decalcification, and the problem such as oral ulcer, decayed tooth just easily creates.During being so with facing, decayed tooth, the common oral such as gingivitis, oral ulcer disease, must treat early, and therefore this just causes the interference to orthodontics.
In orthodontics process, adopt some pre-antieurodontic methods as fissure blockade, be coated with fluorine paint or fluorine-containing collutory, use toothpaste with fluoride to brush teeth, because fluorine can strengthen the capacity antacid of tooth.
Some patients or the head of a family be everlasting to complain in face of doctor have on tooth set brush teeth inconvenience or brush unclean.The change of breed bacteria and internal environment of oral cavity in oral cavity is the major reason causing oral ulcer.
Oral ulcer is commonly called as " aphtha ", is a kind of common ulcerative damages disease betiding oral mucosa, is more common in inside lip, the position such as tongue, tongue abdomen, cheek mucosa, vestibule ditch, soft palate, the mucosa at these positions lack keratinization layer or keratinization poor.Tongue ulcer refers to the oral ulcer betiding tongue, tongue abdominal part position.Sharp ache during oral ulcer outbreak, local causalgia is obvious, and severe patient also can affect diet, speak, and causes very big inconvenience to daily life.
Summary of the invention
The invention provides the collutory used during a kind of orthodontic is corrected, nursed one's health by Chinese medicine, deep layer cleaning oral cavity, mothproof, whitening, improve internal environment of oral cavity, the oral diseases such as pre-ulcer, halitosis.
The collutory that orthodontic of the present invention uses during correcting, is prepared by the raw material of following parts by weight: Aloe 15-18 part, green tea 15-18 part, Cortex erythrinae 10-15 part, Radix Zanthoxyli 3-8 part, surfactant 1-3 part, sodium chloride 1-5 part and deionized water 100 parts.
As preferably, prepare by following parts by weight:
Aloe 15 parts, green tea 15 parts, Cortex erythrinae 15 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Other preferred versions are: Aloe 18 parts, green tea 18 parts, Cortex erythrinae 13 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Chinese medicine ointment of the present invention, prepare in the steps below:
Take said components according to quantity, extract Aloe, green tea, Cortex erythrinae, Cortex Phellodendri effective ingredient respectively, concentrating under reduced pressure, mix with surfactant and sodium chloride, be dissolved in deionized water.
Subpackage, every bottle of 200ml.During use in rinsing the mouth and mouth, tell during rinsing the mouth 1-2 divides.
Pharmacology analysis:
Aloe: nature and flavor: bitter, cold.Bactericidal action, antiinflammatory action, moistening beautification function, lets out effect under stomach invigorating, the heart tonifying effect of invigorating blood circulation, immunity and regeneration, immunity and antitumor action, Detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.Pathogenic fire purging; Removing toxic substances; Blood stasis dispelling; Parasite killing.Argument is red; Constipation; Nebulousurine; Hematuria; Pediatric epilepsy scared; Infantile malnutrition; Burn and scald; Women's amenorrhea; Hemorrhoid; Scabies; Carbuncle furuncle and phyma poison; Traumatic injury.
Green tea: without the tea made that ferments, remain the natural materials of fresh leaf, the tea polyphenols contained, catechin, chlorophyll, caffeine, aminoacid, vitamins and other nutritious components are also more.These natural nutrition compositions in green tea have special-effect to anti-aging, anti-cancer, anticancer, sterilization, antiinflammatory etc.
Cortex erythrinae: (1) calm, analgesic activity: to mouse peritoneal Zhu She Cortex araliae chinensis Total saponin 1850mg/kg, the CNS inhibition effect of pentobarbital sodium, chlorpromazine can be worked in coordination with; The central excitation effect of amfetamine can be resisted, but the toxicity of the caused convulsions of pentylenetetrazole and caffeine can not be resisted, obviously can increase the threshold of pain of thermostimulation (hot plate method), reduce the mouse writhing reaction that acetic acid causes, there is certain analgesic activity.
(2) anti-experimental character gastric ulcer effect: Cortex araliae chinensis decoct 4g/kg is to protecting rat pylorus ligation, chemical (indomethacin brings out), irritability and reserpine gastric ulcer after rat oral gavage or lumbar injection, and the chronic gastric ulcer that Dichlorodiphenyl Acetate brings out also has certain effect.200% Cortex araliae chinensis decoct 0.2-0.4ml, can make cholinergic pathway bar shrink, and illustrates that it has the effect promoting stomach motion.White Bei Ye Cortex araliae chinensis water decoction (1:1) has inhibitory action to Mouse Stomach intestine movement, act on and increase with dosage and strengthen, phentolamine and Propranolol its inhibitory action capable of blocking, therefore its effect may be relevant with the activity of the α of adrenergic nerve and beta receptor.Get its inhibitory action to ulcer herein.
Radix Zanthoxyli: blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dispelling wind and removing obstruction in the collateral, removing toxic substances and promoting subsidence of swelling.For injury from falling down, stomachache, toothache, rheumatic arthralgia, venom; Externally treating burns and scalds.
Surfactant (surfactant), refers to the material adding the interface state generation significant change that can make its solution system on a small quantity.There is fixing hydrophilic and oleophilic group, align in the surface energy of solution.The molecular structure of surfactant has amphipathic: one end is hydrophilic group, and the other end is hydrophobic group; Hydrophilic group is often polar group, and as carboxylic acid, sulfonic acid, sulphuric acid, amino or amido and salt thereof, hydroxyl, amide groups, ehter bond etc. also can be used as polar hydrophilic group; And hydrophobic group is often nonpolar hydrocarbon chain, as 8 above hydrocarbon chains of carbon atom.Surfactant is divided into ionic surfactant (comprising cationic surfactant and anion surfactant), nonionic surfactant, amphoteric surfactant, compound surfactant, other surfactants etc.
Surfactant is the molecule formed by two kinds of distinct particles, and a kind of particle has extremely strong lipophile, another kind of then have extremely strong hydrophilic.After being dissolved in the water, surfactant can reduce the surface tension of water, and improves the solubility of each traditional Chinese medicine extraction component.
Chinese medicine formula of the present invention, Aloe is in order to sterilization, antiinflammatory; Green tea in order to sterilization, antibacterial; Cortex erythrinae suppresses ulcer; Radix Zanthoxyli removing toxic substances and promoting subsidence of swelling; Cleaning oral cavity, mothproof hemostasis and anti-inflammation, improve the internal environment of oral cavity during mouth cavity orthodontic is corrected, reduce the probability of concurrent oral disease.
Clinical trial
Choose mouth cavity orthodontic and correct patient 50 people, be divided into two groups at random, matched group and experimental group;
Do not use collutory during matched group wears facing, during experimental group wears facing, rinsing the mouth every day collutory of the present invention sooner or later once.
Therapeutic outcome:
Regular return visit two groups of patients in 3 months, there is oral ulcer in various degree in matched group 7 people, 3 people occur that halitosis or halitosis increase the weight of, sickness rate 40%; There is slight ulcer and comparatively fast fully recover in experimental group 2 people.
Collutory of the present invention has good sterilization, antibacterial, anti-inflammatory effect, significantly can improve the oral health during mouth cavity orthodontic is corrected, improve patients ' life quality.
Detailed description of the invention
Embodiment 1
Aloe 15 parts, green tea 15 parts, Cortex erythrinae 15 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Embodiment 2
Aloe 18 parts, green tea 18 parts, Cortex erythrinae 13 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Embodiment 3
Aloe 16 parts, green tea 16 parts, Cortex erythrinae 14 parts, Radix Zanthoxyli 4 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Chinese medicine ointment of the present invention, prepare in the steps below:
Take said components according to quantity, extract Aloe, green tea, Cortex erythrinae, Cortex Phellodendri effective ingredient respectively, concentrating under reduced pressure, mix with surfactant and sodium chloride, be dissolved in deionized water.
Subpackage, every bottle of 200ml.During use in rinsing the mouth and mouth, tell during rinsing the mouth 1-2 divides.
Claims (3)
1. the collutory used during orthodontic rectification, is characterized in that being prepared by the raw material of following parts by weight: Aloe 15-18 part, green tea 15-18 part, Cortex erythrinae 10-15 part, Radix Zanthoxyli 3-8 part, surfactant 1-3 part, sodium chloride 1-5 part and deionized water 100 parts.
2. the collutory used during orthodontic rectification according to claim 1, is characterized in that being prepared by the raw material of following parts by weight: Aloe 15 parts, green tea 15 parts, Cortex erythrinae 15 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
3. the collutory used during orthodontic rectification according to claim 1, is characterized in that being prepared by the raw material of following parts by weight: Aloe 18 parts, green tea 18 parts, Cortex erythrinae 13 parts, Radix Zanthoxyli 5 parts, 2 parts, surfactant, 3 parts, sodium chloride and deionized water 100 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510990320.0A CN105496873A (en) | 2015-12-24 | 2015-12-24 | Mouthwash used during orthodontic treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510990320.0A CN105496873A (en) | 2015-12-24 | 2015-12-24 | Mouthwash used during orthodontic treatment |
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| Publication Number | Publication Date |
|---|---|
| CN105496873A true CN105496873A (en) | 2016-04-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510990320.0A Pending CN105496873A (en) | 2015-12-24 | 2015-12-24 | Mouthwash used during orthodontic treatment |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107693442A (en) * | 2017-09-14 | 2018-02-16 | 南通荣成医药化工有限公司 | A kind of efficient sterilizing mouthwash |
| CN108743497A (en) * | 2018-05-22 | 2018-11-06 | 泉州御汉芳生物科技有限公司 | A kind of antibacterial mouthwash of plant source and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0377817A (en) * | 1989-08-21 | 1991-04-03 | Taiyo Kagaku Co Ltd | Oral cavity washing agent containing tea-polyphenol compound |
| CN101391011A (en) * | 2008-11-03 | 2009-03-25 | 朱惠芬 | Pure Chinese herbal medicine gargle water for treating oral inflammation |
| CN102000189A (en) * | 2010-11-10 | 2011-04-06 | 韩盛华 | Traditional Chinese medicine spray liniment for diminishing inflammation and stopping pains and preparation method thereof |
| CN104288047A (en) * | 2014-10-10 | 2015-01-21 | 高莉萍 | Green tea mouth wash |
| CN104887569A (en) * | 2015-05-26 | 2015-09-09 | 柳州市亿廷贸易有限责任公司 | Mouth wash |
-
2015
- 2015-12-24 CN CN201510990320.0A patent/CN105496873A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0377817A (en) * | 1989-08-21 | 1991-04-03 | Taiyo Kagaku Co Ltd | Oral cavity washing agent containing tea-polyphenol compound |
| CN101391011A (en) * | 2008-11-03 | 2009-03-25 | 朱惠芬 | Pure Chinese herbal medicine gargle water for treating oral inflammation |
| CN102000189A (en) * | 2010-11-10 | 2011-04-06 | 韩盛华 | Traditional Chinese medicine spray liniment for diminishing inflammation and stopping pains and preparation method thereof |
| CN104288047A (en) * | 2014-10-10 | 2015-01-21 | 高莉萍 | Green tea mouth wash |
| CN104887569A (en) * | 2015-05-26 | 2015-09-09 | 柳州市亿廷贸易有限责任公司 | Mouth wash |
Non-Patent Citations (2)
| Title |
|---|
| 王建新 等: "《化妆品植物原料大全》", 30 June 2012 * |
| 褚洪标 等: "《井冈山区域实用中草药图谱》", 31 July 2015 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107693442A (en) * | 2017-09-14 | 2018-02-16 | 南通荣成医药化工有限公司 | A kind of efficient sterilizing mouthwash |
| CN108743497A (en) * | 2018-05-22 | 2018-11-06 | 泉州御汉芳生物科技有限公司 | A kind of antibacterial mouthwash of plant source and preparation method thereof |
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20160420 |