CN105482987A - Thermal cycler - Google Patents
Thermal cycler Download PDFInfo
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- CN105482987A CN105482987A CN201510844750.1A CN201510844750A CN105482987A CN 105482987 A CN105482987 A CN 105482987A CN 201510844750 A CN201510844750 A CN 201510844750A CN 105482987 A CN105482987 A CN 105482987A
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- Prior art keywords
- lock
- buckling piece
- thermal cycler
- handle
- plate
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
Abstract
The invention relates to a thermal cycler, and discloses a thermal cycler with a sample holder fixing mechanism. The thermal cycler comprises a case (2), a cover (1) and the fixing mechanism for fixing a sample holder. The fixing mechanism comprises a handle (202) and handle mounting seats (203), the handle (202) can reciprocate in the handle mounting seats (203), positioning grooves (220) are formed in the handle (202) and are L-shaped hook grooves, openings are formed in the tops of the L-shaped hook grooves, the bottoms of the L-shaped hook grooves are extended along pull-out or push-in directions of the handle (202), and positioning dowels (210) which are matched with the positioning grooves (220) are arranged on the sample holder (201). The thermal cycler has the advantages that the thermal cycler is provided with the sample holder fixing mechanism, and the handle can be pushed and pulled, so that the sample holder and the handle can be fixed relatively, the sample holder can be replaced conveniently and quickly, and the work safety of the sample holder and the accuracy of experimental data can be guaranteed.
Description
Technical field
The present invention relates to a kind of thermal cycler, particularly relate to a kind of thermal cycler with specimen holder fixed mechanism.
Background technology
Biochemical reaction needs reaction liquid composition to carry out under the condition of precise control of temperature usually, such as polymerase chain reaction (english abbreviation PCR).Reaction liquid composition is contained in sample hose, and sample hose is made up of the plastics of heat conduction or other materials usually, and seals, and to avoid evaporating, is then inserted into by sample hose in the sample well that specimen holder is dug.Specimen holder is made up by cutting or other forming technique of metal or other thermally conductive materials usually, by heating-cooling device, and the temperature of Quality control seat, and by heat transfer, realize the control to reaction liquid temperature in specimen holder.
Generally there is following defect in existing thermal cycler:
(1) in order to make sample hose contact well with sample well, to ensure heat-transfer effect, usually one pressure assembly is set at sample hose top, exerts pressure to sample hose top, institute's plus-pressure had both ensured that sample hose was indeformable and had broken, and ensured again to contact well with sample well bottom sample hose.Operate sample hose for the convenience of the users, as inserted or taking out sample hose, usually need first to shed or discharge institute's plus-pressure, again pressure assembly is removed, thus expose specimen holder, and be at present all generally realize exerting pressure or pressure leak process by some physical constructions for compressing the pressure assembly of sample hose, and physical construction of the prior art exists, and complex structure, volume are large, high in cost of production defect.
(2) when specimen holder is fixed on the cabinet of thermal cycler, can a lid be set above specimen holder, owing to needing to operate sample hose, change specimen holder when testing, therefore generalized case lower cover is all connected on cabinet by a rotating shaft, when operating sample hose, Cover opening is turned to thermal cycler rear portion, specimen holder can be exposed to operator face and operates for operator.But lid of the prior art generally covers on cabinet by own wt, its can not closed-lock on cabinet, also the simple fastening structure between some simple lid and cabinets is there is in prior art, but current fastening structure generally exists fastening, and effect is poor, open, fasten the defects such as inconvenience, therefore certain work safety hidden danger can be produced, also certain ectocine can be produced to experimental result.
(3) thermal cycler often needs to carry out heating cooling to the sample hose of different size, therefore the specimen holder on cabinet needs often to change, to meet different tests demand, therefore should handled easily person quick-replaceable different size specimen holder, ensure that specimen holder not easily moves and comes off in work and transportation again, and want that structure is simple, cost is low, become the difficult point in thermal cycler structure design, be then difficult to the security of guarantee work and the accuracy of experimental data.
Summary of the invention
The present invention is directed to the above-mentioned defect existed in thermal cycler in prior art, provide a kind of thermal cycler.
In order to solve the problems of the technologies described above, the present invention is solved by following technical proposals:
Thermal cycler, comprise cabinet and cover the lid on cabinet, cabinet is fixed with specimen holder, and specimen holder is provided with sample hose, also comprise the fixed mechanism for fixed sample seat, for compressing the pressure assembly of sample hose and the knocker mechanism for fastening lid and cabinet.
Wherein, specimen holder fixed mechanism, comprise specimen holder, the handle mount pad also comprising handle and be fixed on cabinet, shake hands through handle mount pad and can handle mount pad in to-and-fro movement, handle is provided with locating slot, and locating slot is top end opening, bottom extends along handle pull-out or direction of propulsion the L shape hook groove formed, and specimen holder is provided with the tommy coordinated with locating slot.When needs to be changed specimen holder or are fixing, by the push-and-pull to handle, tommy is made to snap in the extending part of locating slot from the opening end of locating slot, or the opening end from the extending part relative movement of locating slot to locating slot, the fixing of specimen holder can be realized or take out, this kind of mode is simple to operate, fixed, both can realize the convenient changing of specimen holder, can ensure again the security of specimen holder work and the accuracy of experimental data.
As preferably, what handle comprised two latch and was connected two latch ends pulls plate, two latch and pull plate handle is configured to U-shaped, and two latch are equipped with at least one locating slot.Handle is designed to this kind of simple structure and can saves cost, is in thermal cycler cabinet external mounting simultaneously, therefore can not produces any impact to other serviceabilitys of thermal cycler due to it.The quantity of locating slot depends on the specification of this thermal cycler and the degree to specimen holder stability requirement, under the prerequisite of comprehensive cost and fixed effect, sets according to actual needs.
As preferably, also comprise the limited screw be fixed on cabinet, latch is provided with stopper slot, and limited screw is fixed in stopper slot, and stopper slot is long strip shape groove and its length direction is handle vibration-direction.The effect of limited screw can effectively prevent handle to be completely pulled out of.
As preferably, also comprise elasticity and be connected to ball on cabinet, latch is also provided with at least two with the ball hole of ball engagement, ball passes in and out ball hole in the mode of elastic telescopic.Ball can make operator pass through to pull feel to distinguish, and whether tommy is in locating slot opening end.
As preferably, also comprise the pressure assembly compressing sample hose, pressure assembly comprises the pressure plate for compressing sample hose, also comprises the armature moved up and down for driving pressure plate, be fixed with the electro-magnet driving armature to move up and down above armature, electro-magnet is fixed on lid internal surface.By rising or the decline of the mode driving pressure mechanism of electro-magnet, it not only has the features such as structure is simple, cost is low, control because electro-magnet can realize electronic remote simultaneously, then the pressure making to be applied to sample hose top can Long-distance Control, improve the automatization of thermal cycler, intelligent level, operator are exerted a force more convenient, accurate.
As preferably, pressure assembly is also comprised and is positioned at pressure plate above sample hose and the web plate be connected with pressure plate by guide rod, is provided with pressure spring and pressure spring is enclosed within guide rod between web plate and pressure plate, and armature is fixed on web plate.When needs apply pressure to sample, armature applies downward pressure to web plate, web plate is applying pressure by pressure spring to pressure plate, then the force process of pressure plate to sample hose top is realized, owing to being provided with pressure spring between web plate and pressure plate, thus certain shock absorption is played to the power that armature is downward, ensure the stability being applied to sample hose top pressure, avoid sample hose to break because of stressed suddenly.
As preferably, pressure mechanism also comprises and is vertically fixed in thermal cycler upper slide bar, slide bar upper end is fixed on lid internal surface, the slide bar the other end passes web plate and web plate can slide up and down along slide bar, on slide bar, cover has return spring and return spring one end is against on web plate lower surface, and the other end is against the bottom of slide bar.When needs operate sample hose, under the effect of return spring, web plate is moved up, zero position got back to by web plate band moving armature, and drive pressure plate to depart from sample hose top, finally remove pressure assembly, exposed sample seat, with handled easily human users, owing to being provided with return spring on slide bar, makes whole pressure assembly operate more convenient.
As preferably, guide rod and slide bar adopt guide screw and slide bar screw respectively.Guide rod and slide bar all adopt screw, make the assembling of guide rod and slide bar simple, improve the efficiency of assembling of whole pressure assembly.
As preferably, electro-magnet can adopt dissimilar or different electromagnetic force, and apply different pressure to meet to dissimilar sample hose, the quantity of the electromagnetism simultaneously adopted also can be decided according to the actual requirements.
As preferably, also comprise the knocker mechanism for fastening lid and cabinet, knocker mechanism comprises the Connection Block be fixed on lid and the lower buckling piece be fixed on cabinet, Connection Block is provided with rotating upper buckling piece and lock-bit part, lower buckling piece is provided with fastening rod, upper buckling piece has the fastening conduit coordinated with fastening rod, lock-bit part is provided with lock-bit projection, upper buckling piece is provided with the lock-bit recess with lock-bit male cooperation, fastening rod is used for entering fastening conduit and promoting upper buckling piece rotates fastening conduit is stuck in fastening rod and makes lock-bit recess be fastened on lock-bit projection, be provided with for making lock-bit part overlay the extension spring on upper buckling piece between lock-bit part and Connection Block, also comprise for pressing lock-bit part and making lock-bit part rotate with the pressing piece making lock-bit recess and lock-bit projection throw off.
As preferably, Connection Block comprises left plate, right side plate and the end plate for being connected left plate and right side plate, is equipped with groove thus is configured for holding the cavity of lower buckling piece bottom left plate and right side plate; Upper buckling piece and lock-bit part are all arranged between left plate and right side plate, and lock-bit part upper end is stretched out structure of connection seat and become the press-side pressed for pressing piece.Connection Block is arranged to above-mentioned form, make when locking state, the bottom of upper buckling piece, lock-bit part and lower buckling piece are all positioned at the inside of Connection Block, thus make whole Bolting structure compacter, also effectively reduce lid with the gap between cabinet simultaneously.
As preferably, lock-bit part is provided with arc groove, upper buckling piece is provided with the arc convex coordinated with arc groove, and fastening rod enters the upper buckling piece of fastening conduit promotion and upwards rotates and the arc groove on the arc convex of buckling piece promotion lock-bit part is rotated to make lock-bit part.By arranging the arc convex and arc groove that cooperatively interact on upper buckling piece and lock-bit part; reactive force is applied by arc; buckling piece can be made more steady to lock-bit part force; avoid stress concentration; reduce wearing and tearing between the two, certain protective role is played to upper buckling piece and lock-bit part.
As preferably, pressing piece is provided with the return spring that pressing piece is resetted.Lid is provided with the mounting groove for installing pressing piece, and this return spring one end is against pressing piece end, the other end be against on lid for pressing piece is installed mounting groove bottom, after pressing piece presses, realize the reset of pressing piece downwards.
As preferably, Connection Block is provided with the coupling shaft for connecting upper buckling piece, and upper buckling piece is provided with the connecting hole coordinated with coupling shaft, is provided with the first torsion spring and the first torsion spring set is located on coupling shaft in connecting hole.Knocker can be made under the effect of the first torsion spring when unlocking, first torsion spring can apply a downward power to upper buckling piece, buckling piece can be rotated down fast, fasten conduit and depart from fastening rod fast, simultaneously also in knocker locking process the first torsion spring on buckling piece apply a downward power, the lock-bit recess of buckling piece can be made can be closely fastened in the lock-bit projection of lock-bit part.By the elastic force of the first torsion spring, realize the unblock of knocker and lock.
As preferably, the side that lid and cabinet are provided with knocker mechanism is relatively connected by rotating shaft, and rotating shaft is provided with and can makes automatically rebounding open second torsion spring of lid.
The present invention, owing to have employed above technical scheme, has significant technique effect:
The present invention arranges specimen holder fixed mechanism on thermal cycler, fixing between specimen holder and handle is realized by the push-and-pull of handle, it is simple, easy to operate that it has structure, both can realize the convenient changing of specimen holder, the security of specimen holder work and the accuracy of experimental data can have been ensured again.
Accompanying drawing explanation
Fig. 1 is the structural representation of embodiments of the invention 1;
Fig. 2 is the local structure formula schematic diagram of Fig. 1;
Fig. 3 is the structural representation of shaking hands in Fig. 1.
The structure schematic diagram of Fig. 4 embodiment of the present invention 2;
Fig. 5 is the local structure schematic diagram of Fig. 4;
Fig. 6 is the structural representation of the embodiment of the present invention 3;
Fig. 7 is the released state structural representation of embodiment 3;
Fig. 8 is the locking state structural representation of embodiment 3;
Fig. 9 is the structural representation of upper buckling piece in Fig. 6;
Figure 10 is the structural representation of lock-bit part in Fig. 6.
The toponym that in accompanying drawing, each number designation refers to is as follows: 1-lid, 2-cabinet, 3-rotating shaft, 4-the second torsion spring, 101-Connection Block, 102-lower buckling piece, 103-upper buckling piece, 104-lock-bit part, 105-extension spring, 106-pressing piece, 107-the first torsion spring, 110-left plate, 111-end plate, 112-right side plate, 113-cavity, 114-coupling shaft, 120-fastening rod, 130-fasten conduit, 131-lock-bit recess, 132-arc convex, 133-connecting hole, 140-lock-bit is protruding, 141-arc groove, 160-return spring, 201-specimen holder, 202-handle, 203-handle mount pad, 204-limited screw, 205-ball, 206-air duct board, 210-tommy, 221-latch, 222-pull plate, 220-locating slot, 223-stopper slot, 250-ball hole, 311-armature, 312-electro-magnet, 321-latch hook, 322-hook groove, 331-pressure plate, 332-guide rod, 333-web plate, 334-pressure spring, 335-slide bar, 336-return spring, 341-sample hose.
Embodiment
Below in conjunction with accompanying drawing and embodiment, the present invention is described in further detail.
Embodiment 1
Thermal cycler, comprise cabinet 2 and cover the lid 1 on cabinet 2, cabinet 2 is fixed with specimen holder 201, specimen holder 201 is provided with sample hose 341, also comprise the fixed mechanism for fixed sample seat, specimen holder fixed mechanism, as shown in Figure 1-Figure 3, comprise specimen holder 201, the handle mount pad 203 also comprising handle 202 and be fixed on cabinet, cabinet is provided with air duct board 206, namely handle mount pad 203 is fixed on air duct board, handle mount pad 203 is provided with rectangular opening, handle 202 passes handle mount pad 203 and can in to-and-fro movement in mount pad 203 of shaking hands, wherein, handle 202 comprise two latch 221 be connected two latch 221 ends pull plate 222, two latch 221 with pull plate 222 handle 202 be configured to U-shaped, the end of two latch 221 is each passed through the rectangular opening on the handle mount pad 203 being positioned at air duct board 206 both sides, and two latch 221 all can synchronous reciprocating motion back and forth in rectangular opening.
Handle 202 is provided with locating slot 220, locating slot 220 to be positioned on latch and each latch 221 to be equipped with two locating slots 220, the L shape hook groove that locating slot 220 is top end opening, bottom extends along handle 202 pull-out direction and formed, specimen holder 201 is provided with the tommy 210 coordinated with locating slot 220.It is inner that tommy 210 enters locating slot 220 from the opening end of locating slot 220, after handle 202 advances, then snap in the extending part of locating slot 220, can realize the fixing of specimen holder 201.
Also comprise the limited screw 204 be fixed on cabinet and the ball 205 be connected to by coil tension spring on cabinet, latch 221 is provided with stopper slot 223, limited screw 204 is fixed in stopper slot 223, and stopper slot 223 is for long strip shape groove and its length direction is handle 202 vibration-direction.Latch 221 is also provided with two ball holes 250 coordinated with ball 205, two balls 205 are set up in parallel along handle 202 direction of motion, ball 205 passes in and out ball hole 250 in the mode of elastic telescopic, handle 202 is in pull-out or progradation, ball 205 is in retracted position and enters in two ball holes 250, so that provide the feel of handle 202 movement to operator, whether tommy 210 is in locating slot 220 opening end to make operator pass through to pull feel to distinguish, makes whole operating process more perfect.
When specimen holder 201 changed by needs, operator apply pulling force by the plate 222 that pulls of handle 202 to handle 202, handle 202 is drawn out, tommy 210 relative movement on specimen holder 201, exit from the extending part of locating slot 220, relative movement, to the opening end of locating slot 220, is now taken out by specimen holder 201 and is changed; After replacing, tommy 210 on new specimen holder 201 is introduced into the opening end of locating slot 220, then a thrust is applied to handle 202, tommy 210 is made to snap in the extending part of locating slot 220, the locking to fresh sample seat can be realized, ensure the security of work and the accuracy of experimental data.Simultaneously after specimen holder 201 takes out, owing to being provided with stopper slot 223 on the latch 221 of handle 202, and be provided with limited screw 204 in stopper slot 223, therefore can effectively prevent handle 202 to be completely pulled out of.
The side that lid 1 and cabinet 2 are provided with knocker mechanism is relatively connected by rotating shaft 3, and rotating shaft 3 is provided with and can makes automatically rebounding open second torsion spring 4 of lid.When knocker mechanism is in released state, namely when the opening direction of the fastening conduit 130 on upper buckling piece 103 is downward, when fastening conduit 130 is not fastened on fastening rod 120 state, lid 1 automatically can be upspring and be opened under the effect of the second torsion spring 4, helping external force to open lid without the need to relending, making whole thermal cycler more convenient to operate.
Embodiment 2
With embodiment 1, difference is, the pressure assembly for compressing sample hose is also comprised in thermal cycler, as Fig. 4, shown in Fig. 5, this pressure assembly comprises pressure plate 331 for compressing sample hose 341 and the web plate 333 be connected with pressure plate 331 by guide rod 332, pressure spring 334 is provided with and pressure spring 334 is enclosed within guide rod 332 between web plate 333 and pressure plate 331, also comprise the slide bar 335 be vertically fixed on thermal cycler, slide bar 335 one end is fixed on lid 1 internal surface, the other end passes web plate 333 and web plate 333 can slide up and down along slide bar 335, on slide bar 335, cover has return spring 336 and return spring 336 one end is against on web plate 333 lower surface, the other end is against the bottom of slide bar 335.
Also comprise the armature 311 moved up and down for driving pressure mechanism in pressure assembly, armature 311 is fixed on web plate 333, and be fixed with the electro-magnet 312 driving armature 311 to move up and down above armature 311, electro-magnet is fixed on lid 1 internal surface.
The present embodiment is when operating, and the guide rod 332 in pressure mechanism and slide bar 335 adopt guide screw and slide bar screw respectively, and when electro-magnet 312 coil is not energized, armature makes web plate 333 be positioned at a station under the elastic force effect of return spring 336; After electro-magnet 312 coil electricity, produce electromagnetic force, make armature 311 overcome the reactive force of return spring 336 to pressing down, make web plate 333 be positioned at another station, specific operation process is as follows:
When electro-magnet 312 is in switch-on regime, armature 311 is under the effect of electromagnetic force, overcome the reactive force of return spring 336, move down and promote web plate 333 and move down, then make web plate 333 drive pressure plate 331 to move downward until with sample hose 341 top contact.Under the effect of electromagnetic force, web plate 333 continues to move downward, now pressure plate 331 has moved and has put in place, thus under the effect of pressure spring 334, web plate 333 is exerted a force to pressure plate 331 indirectly by pressure spring 334, then realize pressure plate 331 pairs of sample hose 341 tops and apply downward pressure, make the bottom pressing close to sample well that sample hose 341 is smooth, ensure heat-transfer effect.
When electro-magnet 312 is in off-position, armature 311 no longer applies downward power to web plate 333, now, under the effect of return spring 336, web plate 333 is with moving armature 311 to move upward, web plate 333 drives pressure plate 331 also to move upward simultaneously, makes pressure plate 331 away from sample hose 341 top, thus sheds the pressure of pressure plate 331.
The electro-magnet 312 adopted in the present embodiment can realize electronic remote and control, then the pressure making to be applied to sample hose 341 top can Long-distance Control, improve the automatization of thermal cycler, intelligent level, also be convenient to user to the control being applied to sample hose 341 top pressure simultaneously, make control mode diversification more, as adopted touchscreen button, the mode such as wired or wireless realizes to its pressure control.
Embodiment 3
With embodiment 1, difference is, the knocker mechanism for fastening lid and cabinet is also comprised in thermal cycler, as shown in Fig. 6-Figure 10, comprise the Connection Block 101 be fixed on lid 1 and the lower buckling piece 102 be fixed on cabinet 2, Connection Block 101 is provided with rotating upper buckling piece 103 and lock-bit part 104, Connection Block 101 comprises left plate 110, right side plate 112 and the end plate 111 for being connected left plate 110 and right side plate 112, left plate 110 be equipped with groove bottom right side plate 112 thus make Connection Block substructure become cavity 113 for holding lower buckling piece 102, two coupling shafts 114 are provided with between the left plate 110 of Connection Block 101 and right side plate 112, two coupling shafts 114 are respectively used to connect buckling piece 103 and lock-bit part 104, and upper buckling piece 103 and lock-bit part 104 all can rotate around coupling shaft 114, go up buckling piece 103 simultaneously and be provided with the connecting hole 133 coordinated with coupling shaft 114, be provided with the first torsion spring 107 in connecting hole 133 and the first torsion spring 107 is set on coupling shaft 114.Upper buckling piece 103 and lock-bit part 104 are all arranged between left plate 110 and right side plate 112, and the press-side that Connection Block 101 is configured to press for pressing piece 106 is stretched out in lock-bit part 104 upper end.
Lower buckling piece 102 is provided with fastening rod 120, upper buckling piece 103 has the fastening conduit 130 coordinated with fastening rod 120, lock-bit part 104 is provided with lock-bit projection 140, upper buckling piece 103 is provided with the lock-bit recess 131 coordinated with lock-bit protruding 140, fastening rod 120 upwards rotates fastening conduit 130 and fastening rod 120 are pinned and when lock-bit recess 131 is fastened in lock-bit projection 140 for entering to fasten conduit 130 and promote upper buckling piece 103, to make to be provided with between lock-bit part 104 and Connection Block 101 for making lock-bit part 104 overlay the extension spring 105 on upper buckling piece 103, also comprise for pressing lock-bit part 104 and making lock-bit part 104 rotate the pressing piece 106 making lock-bit recess 131 throw off with lock-bit protruding 140, pressing piece 106 is provided with the return spring 160 that pressing piece 106 is resetted, extension spring 105 makes lock-bit part 104 reset
Lock-bit part 104 is provided with arc groove 141, upper buckling piece 103 is provided with the arc convex 132 coordinated with arc groove 141, and fastening rod 120 enters and fastens conduit 130 and promote upper buckling piece 103 and upwards to rotate and the arc groove 141 that the arc convex 132 of buckling piece 103 is promoted on lock-bit part 104 rotates to make lock-bit part 104.
As shown in Figure 7, when needs are locked lid 1, directly a downward power is applied to lid 1, make lid 1 close to cabinet 2 upper surface, until the lower buckling piece 102 upper end fastening rod 120 on cabinet 2 upper surface contacts with upper buckling piece 103, along with lid 1 continue press down, fastening rod 120 applies a reactive force upwards to upper buckling piece 103, buckling piece 103 is turned clockwise, the fastening conduit 130 of buckling piece 103 is made to hook fastening rod 120, go up buckling piece 103 acts on lock-bit part 104 arc groove 141 by its arc convex 132 simultaneously, lock-bit part 104 is rotated counterclockwise, this process continues to arc convex 132 and crosses arc groove 141 and depart from arc groove 141 along with lid 1 moves down, now lock-bit part 104 rotates at the clockwise under influence of extension spring 105, upper buckling piece 103 rotates counterclockwise under the effect of the first torsion spring 107, finally make the lock-bit recess 131 buckling piece 103 is positioned at below arc convex 132 be fastened on lock-bit part 104 is positioned at protruding 140 places of lock-bit above arc groove 141, realize the location to upper buckling piece 103, in guarantee, the fastening conduit 130 of buckling piece 103 is fastened in the fastening rod 120 of lower buckling piece 102, then the locking of lid 1 and cabinet 2 is realized.
As shown in Figure 8, when needs unlock lid 1, press pressing piece 106, the press-side of pressing piece 106 pairs of lock-bit parts 104 applies downward pressure, under the effect of pressing piece 106, lock-bit part 104 is rotated counterclockwise, thus lock-bit part 104 lock-bit projection 140 applies a thrust upwards to the lock-bit recess 131 of upper buckling piece 103, buckling piece 103 on jack-up and buckling piece 103 is turned clockwise until lock-bit recess 131 departs from lock-bit protruding 140, then under the effect of the first torsion spring 107, upper buckling piece 103 rotates counterclockwise, make the opening direction of the fastening conduit 130 on buckling piece 103 downward, depart from the fastening rod 120 of lower buckling piece 102, thus realize the unblock of lid 1 and cabinet 2.Meanwhile, after pressing piece 106 pairs of lock-bit parts 104 apply the disappearance of downward reactive force, pressing piece 106 can get back to original position under the effect of return spring 160, and lock-bit part 104 gets back to original position under the effect of extension spring 105.
In a word, the foregoing is only preferred embodiment of the present invention, all equalizations done according to the present patent application the scope of the claims change and modify, and all should belong to the covering scope of patent of the present invention.
Claims (10)
1. thermal cycler, comprise cabinet (2) and cover the lid (1) on cabinet (2), cabinet (2) is fixed with specimen holder (201), specimen holder (201) is provided with sample hose (341), it is characterized in that: for the fixed mechanism of fixed sample seat, fixed mechanism comprises handle (201) and is fixed on the handle mount pad (203) on cabinet, handle (202) passes handle mount pad (203) and can in to-and-fro movement in mount pad (203) of shaking hands, handle (202) is provided with locating slot (220), locating slot (220) is top end opening, the L shape hook groove that bottom extends along handle (202) pull-out or direction of propulsion and formed, specimen holder (201) is provided with the tommy (210) coordinated with locating slot (220).
2. thermal cycler according to claim 1, it is characterized in that: also comprise the knocker mechanism for fastening lid and cabinet, knocker mechanism comprises the Connection Block (101) be fixed on lid (1) and the lower buckling piece (102) be fixed on cabinet (2), Connection Block (101) is provided with rotating upper buckling piece (103) and lock-bit part (104), lower buckling piece (102) is provided with fastening rod (120), upper buckling piece (103) has the fastening conduit (130) coordinated with fastening rod (120), lock-bit part (104) is provided with lock-bit projection (140), upper buckling piece (103) is provided with the lock-bit recess (131) coordinated with lock-bit projection (140), fastening rod (120) is rotated to make fastening conduit (130) be stuck in fastening rod (120) upper and make lock-bit recess (131) be fastened on lock-bit projection (140) for entering to fasten conduit (130) and promote upper buckling piece (103), be provided with for making lock-bit part (104) overlay the extension spring (105) on upper buckling piece (103) between lock-bit part (104) and Connection Block (101), also comprise for pressing lock-bit part (104) and making lock-bit part (104) rotate with the pressing piece (106) making lock-bit recess (131) and lock-bit projection (140) throw off.
3. thermal cycler according to claim 2, it is characterized in that: lock-bit part (104) is provided with arc groove (141), upper buckling piece (103) is provided with the arc convex (132) coordinated with arc groove (141), and fastening rod (120) enters buckling piece (103) in fastening conduit (130) promotion and upwards rotates and the arc groove (141) on the arc convex of buckling piece (103) (132) promotion lock-bit part (104) is rotated to make lock-bit part (104).
4. thermal cycler according to claim 2, it is characterized in that: Connection Block (101) is provided with the coupling shaft (114) for connecting upper buckling piece (103), upper buckling piece (103) is provided with the connecting hole (133) coordinated with coupling shaft (114), is provided with the first torsion spring (107) and the first torsion spring (107) is set on coupling shaft (114) in connecting hole (133).
5. thermal cycler according to claim 1, it is characterized in that: also comprise the pressure assembly for compressing sample hose (341), pressure assembly comprises the armature (311) that pressure plate and driving pressure plate move up and down, armature (311) top is fixed with the electro-magnet (312) driving armature (311) to move up and down, and electro-magnet (312) is fixed on lid internal surface.
6. thermal cycler according to claim 5, it is characterized in that: the web plate (333) that pressure assembly is comprised pressure plate (331) for compressing sample hose and is connected with pressure plate (331) by guide rod (332), be provided with pressure spring (334) between web plate (333) and pressure plate (331) and pressure spring (334) is enclosed within guide rod (332), armature (311) is fixed on web plate (333); Pressure mechanism also comprises the slide bar (335) be vertically fixed on thermal cycler, slide bar (335) through web plate (333) and web plate (333) can slide up and down along slide bar (335), the upper cover of slide bar (335) has return spring (336) and return spring (336) one end is against on web plate (333) lower surface, and the other end is against the bottom of slide bar (335).
7. thermal cycler according to claim 1, it is characterized in that: handle (202) comprise two latch (221) be connected two latch (221) ends pull plate (222), two latch (221) with pull plate (222) will shake hands (202) be configured to U-shaped, two latch (221) are equipped with at least one locating slot (220).
8. thermal cycler according to claim 7, it is characterized in that: also comprise the limited screw (204) be fixed on cabinet, latch (221) is provided with stopper slot (223), limited screw (204) is fixed in stopper slot (223), and stopper slot (223) is for long strip shape groove and its length direction is handle vibration-direction.
9. thermal cycler according to claim 7, it is characterized in that: also comprise elasticity and be connected to ball (205) on cabinet, latch (221) is also provided with at least two ball holes (250) coordinated with ball (205), ball (205) passes in and out ball hole (250) in the mode of elastic telescopic.
10. thermal cycler according to claim 2, it is characterized in that: Connection Block (101) comprises left plate (110), right side plate (112) and the end plate (111) for being connected left plate (110) and right side plate (112), left plate (110) is equipped with groove with right side plate (112) bottom thus is configured for holding the cavity (113) of lower buckling piece (102); Upper buckling piece (103) and lock-bit part (104) are all arranged between left plate (110) and right side plate (112), and the press-side that Connection Block (101) is configured to press for pressing piece (106) is stretched out in lock-bit part (104) upper end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510844750.1A CN105482987B (en) | 2015-11-27 | 2015-11-27 | thermal cycler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510844750.1A CN105482987B (en) | 2015-11-27 | 2015-11-27 | thermal cycler |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105482987A true CN105482987A (en) | 2016-04-13 |
| CN105482987B CN105482987B (en) | 2018-04-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510844750.1A Active CN105482987B (en) | 2015-11-27 | 2015-11-27 | thermal cycler |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109182107A (en) * | 2018-09-17 | 2019-01-11 | 赵勇 | A kind of latch assembly and its gene detection equipment |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007028860A1 (en) * | 2005-09-06 | 2007-03-15 | Finnzymes Instruments Oy | Thermal cycler with optimized sample holder geometry |
| WO2007054747A1 (en) * | 2005-11-11 | 2007-05-18 | Evogen Ltd | Thermal cycler |
| CN101363001A (en) * | 2008-08-22 | 2009-02-11 | 金银杏生物科技(北京)有限公司 | Sliding mode heat transfer media plate PCR instrument |
| CN201802707U (en) * | 2010-08-04 | 2011-04-20 | 深圳视爵光旭电子有限公司 | Fastening device capable of quickly fixing control box of LED (light-emitting diode) display screen |
-
2015
- 2015-11-27 CN CN201510844750.1A patent/CN105482987B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007028860A1 (en) * | 2005-09-06 | 2007-03-15 | Finnzymes Instruments Oy | Thermal cycler with optimized sample holder geometry |
| WO2007054747A1 (en) * | 2005-11-11 | 2007-05-18 | Evogen Ltd | Thermal cycler |
| CN101363001A (en) * | 2008-08-22 | 2009-02-11 | 金银杏生物科技(北京)有限公司 | Sliding mode heat transfer media plate PCR instrument |
| CN201802707U (en) * | 2010-08-04 | 2011-04-20 | 深圳视爵光旭电子有限公司 | Fastening device capable of quickly fixing control box of LED (light-emitting diode) display screen |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109182107A (en) * | 2018-09-17 | 2019-01-11 | 赵勇 | A kind of latch assembly and its gene detection equipment |
| CN109182107B (en) * | 2018-09-17 | 2021-06-29 | 赵勇 | Lock subassembly and gene check out test set thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105482987B (en) | 2018-04-27 |
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Effective date of registration: 20210514 Address after: 5 / F, No.3 workshop, energy saving science and Technology Park, 391 Wener Road, Xihu District, Hangzhou City, Zhejiang Province, 310000 Patentee after: Hangzhou Langji Scientific Instrument Co.,Ltd. Address before: Room 804, building 23, District 5, Cuiyuan new village, Xihu District, Hangzhou City, Zhejiang Province, 310012 Patentee before: Zhang Jialin |