CN105477493A - Traditional Chinese medicine composition for treating Hashimoto's thyroiditis - Google Patents

Traditional Chinese medicine composition for treating Hashimoto's thyroiditis Download PDF

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Publication number
CN105477493A
CN105477493A CN201510986973.1A CN201510986973A CN105477493A CN 105477493 A CN105477493 A CN 105477493A CN 201510986973 A CN201510986973 A CN 201510986973A CN 105477493 A CN105477493 A CN 105477493A
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parts
chinese medicine
radix
traditional chinese
medicine composition
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Qingdao Changanda Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine composition for treating Hashimoto's thyroiditis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 33-46 parts of knoxia root, 31-39 parts of sauropus spatulifolius, 25-36 parts of raw rehmannia root, 22-29 parts of antler, 18-27 parts of salvia miltiorrhiza, 12-27 parts of radix phytolaccae, 8-16 parts of radix linderae, 5-12 parts of kaempferia galamga, 3-9 parts of radix bupleuri, 4-12 parts of atractylodes macrocephala and 5-13 parts of pinellia tuber. According to the traditional Chinese medicine composition for treating the Hashimoto's thyroiditis, various ingredients are all pure traditional Chinese medicines, which have the effects of soothing liver and regulating Qi, invigorating spleen and nourishing blood, promoting blood circulation to dispel blood stasis and softening and resolving hard mass through being used together, so that the traditional Chinese medicine composition plays roles in protecting and repairing thyroid tissue, the symptoms of patients are effectively improved or relieved, the aim of treating early-phase and no-thyroid-dysfunction-accompanied Hashimoto's thyroiditis is achieved, and no adverse reaction and toxic or side effects is caused.

Description

The Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis.
Background technology
Chronic lymphocytic thyroiditis (HT) is a kind of autoimmune thyroid disease common clinically, histologic characteristics due to primary disease show as diffusivity lymphocytic infiltration, fibrosis, interstitial atrophy and acinous cell acidophilia change, therefore also referred to as chronic lymphocytic thyroiditis.Primary disease is apt to occur in 30 ~ 50 years old women, and its sickness rate is in the trend increased gradually in recent years.Current western medical treatment primary disease takes thyroxin alternative medicine, immunotherapy, operative treatment etc. more, curative effect affirmative, but untoward reaction is many, and easily recurs.The traditional Chinese medicine composition for treating chronic lymphocytic thyroiditis that the present invention prepares, achieves good effect.
Summary of the invention
Technical problem to be solved by this invention is: provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment chronic lymphocytic thyroiditis of human non-toxic's side effect.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
The Chinese medicine composition for the treatment of chronic lymphocytic thyroiditis provided by the invention, be made up of the raw material of Chinese medicine of following weight portion: Radix Knoxiae 33-46 part, Folium Sauropi 31-39 part, Radix Rehmanniae 25-36 part, Cornu Cervi Pantotrichum 22-29 part, Radix Salviae Miltiorrhizae 18-27 part, Radix Phytolaccae 12-27 part, Radix Linderae 8-16 part, Rhizoma Kaempferiae 5-12 part, Radix Bupleuri 3-9 part, Rhizoma Atractylodis Macrocephalae 4-12 part, Rhizoma Pinelliae 5-13 part.
Preferably, Chinese medicine provided by the invention is made up of the raw material of Chinese medicine of following weight portion: Radix Knoxiae 40 parts, Folium Sauropi 33 parts, 30 parts, the Radix Rehmanniae, 26 parts, Cornu Cervi Pantotrichum, Radix Salviae Miltiorrhizae 21 parts, Radix Phytolaccae 17 parts, the Radix Linderae 11 parts, Rhizoma Kaempferiae 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, the Rhizoma Pinelliae 9 parts.
Usage and dosage: above-mentioned raw materials, is simmered in water after boiling with high heat 30 minutes after 10 minutes with warm water soaking again, taking liquid 150 milliliters, then add water and two to decoct, filter after twice medicinal liquid mixing, take at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
Clinical report is as follows: 1, in the routine patient of physical data 100, women 41 example, male 59 example.2, the scleroid goiter of diagnostic criteria (1) diffusivity.(2) TgAb (thyroglobulin antibody) and TmAb (thyroid microsomal antibody) significantly increases or reduces with FT4 (serum free thyroxine), FT3 (free serum 3).(3) thyroid fine needle pathology examination by centesis.3, medicinal warm water soaking in of the present invention after 10 minutes, simmers in water after boiling with high heat 30 minutes by Therapeutic Method again, taking liquid 150 milliliters, then adds water and two to decoct, and filters, take after twice medicinal liquid mixing at twice.Twice daily, one after each meal.
The course for the treatment of: 15 days be a course for the treatment of, the 2-5 course for the treatment of need be taken.
4, therapeutic outcome: 4.1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ": cure: clinical symptom disappearance, thyroid is without enlargement, and TgAb, TmAb, FT4, FT3 level is normal; Take a turn for the better: clinical symptoms obviously alleviates, and thyromegaly reduces is on close level normally more than 50%, TgAb, TmAb, FT4, FT3; Effective: clinical symptoms alleviates to some extent, thyromegaly reduces, and TgAb, TmAb, FT4, FT3 level is improved; Do not heal: goiter is reduced not obvious or without reducing, TgAb, TmAb, FT4, FT3 are unchanged or increase the weight of.4.2 results: in 100 routine patients, cure 73 examples, and take a turn for the better 12 examples, and effective 8 examples, total effective rate is 93%.
Beneficial effect of the present invention:
The various component of the present invention is pure Chinese medicine; all medicines share depressed liver-energy dispersing and QI regulating, strengthening spleen and nourishing blood, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving; to parathyroid tissue, there is protection and repair; effective improvement or patients in remission; reach treatment early stage, without chronic lymphocytic thyroiditis's object of dysthyreosis, have no adverse reaction and toxic and side effects.
Detailed description of the invention
Embodiment 1
The Chinese medicine composition of the treatment chronic lymphocytic thyroiditis that the present embodiment provides, is made up of the raw material of Chinese medicine of following weight portion: Radix Knoxiae 40 parts, Folium Sauropi 33 parts, 30 parts, the Radix Rehmanniae, 26 parts, Cornu Cervi Pantotrichum, Radix Salviae Miltiorrhizae 21 parts, Radix Phytolaccae 17 parts, the Radix Linderae 11 parts, Rhizoma Kaempferiae 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, the Rhizoma Pinelliae 9 parts.
Model case:
1. Wang, female, 39 years old, the enlargement of patient's thyroid I degree, heart rate 93 times/min.Thyroid B ultrasonic: bilateral thyromegaly.Take the Chinese medicine composition that the present invention treats chronic lymphocytic thyroiditis to treat, after treating 2 courses for the treatment of, symptom alleviates.Continue to take 3 courses for the treatment of, recovery from illness.
2. Lee, man, 56 years old, starts sleep poor, hypomnesis, irritated, discomfort of neck area after a wheat harvesting period.B ultrasonic display thyroid slightly fills the air enlargement; Chemical examination display TGAb, TPOAb raise, and FT3, FT4, TSH are normal; After taking 2 courses for the treatment of of this medicine, symptom alleviates, and continues 3 courses for the treatment of of taking medicine, recovery from illness.

Claims (2)

1. treat a Chinese medicine composition for chronic lymphocytic thyroiditis, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Radix Knoxiae 33-46 part, Folium Sauropi 31-39 part, Radix Rehmanniae 25-36 part, Cornu Cervi Pantotrichum 22-29 part, Radix Salviae Miltiorrhizae 18-27 part, Radix Phytolaccae 12-27 part, Radix Linderae 8-16 part, Rhizoma Kaempferiae 5-12 part, Radix Bupleuri 3-9 part, Rhizoma Atractylodis Macrocephalae 4-12 part, Rhizoma Pinelliae 5-13 part.
2. Chinese medicine according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Radix Knoxiae 40 parts, Folium Sauropi 33 parts, 30 parts, the Radix Rehmanniae, 26 parts, Cornu Cervi Pantotrichum, Radix Salviae Miltiorrhizae 21 parts, Radix Phytolaccae 17 parts, the Radix Linderae 11 parts, Rhizoma Kaempferiae 8 parts, Radix Bupleuri 6 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, the Rhizoma Pinelliae 9 parts.
CN201510986973.1A 2015-12-26 2015-12-26 Traditional Chinese medicine composition for treating Hashimoto's thyroiditis Pending CN105477493A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102670915A (en) * 2012-05-31 2012-09-19 王中英 Traditional Chinese medicine combination for treating hashimoto thyroiditis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102670915A (en) * 2012-05-31 2012-09-19 王中英 Traditional Chinese medicine combination for treating hashimoto thyroiditis

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Application publication date: 20160413