CN105477295A - Preparation method of extract tablet for treating hyperplasia of mammary glands - Google Patents

Preparation method of extract tablet for treating hyperplasia of mammary glands Download PDF

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Publication number
CN105477295A
CN105477295A CN201510960267.XA CN201510960267A CN105477295A CN 105477295 A CN105477295 A CN 105477295A CN 201510960267 A CN201510960267 A CN 201510960267A CN 105477295 A CN105477295 A CN 105477295A
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parts
preparation
cyclomastopathy
crude drug
immersion sheet
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韦盛盟
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/89—Cyperaceae (Sedge family)
    • A61K36/8905—Cyperus (flatsedge)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

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Abstract

The invention discloses a preparation method of an extract tablet for treating hyperplasia of mammary glands. The preparation method comprises the following steps: step 1, weighing the following raw medicinal materials in parts by weight: 13-18 parts of radix bupleuri, 5-7 parts of cyperus rotundus, 5-7 parts of dried tangerine or orange peel, 8-12 parts of peach kernels, 8-12 parts of medicinal cyathula root, 8-12 parts of caulis spatholobi, 10-15 parts of the seeds of cowherb, 8-12 parts of tetrapanax papyriferus, 10-15 parts of loofah sponge, 8-10 parts of seaweed, 8-10 parts of kelp, 5-8 parts of the bulb of fritillary, and 8-12 parts of oyster; step 2, smashing the weighed raw medicinal materials, mixing the smashed raw medicinal materials with ethyl alcohol, and carrying out digestion to obtain digestion stock solution; and step 3, purifying and diluting the digestion stock solution to obtain leach liquor, adsorbing the leach liquor by adopting a water-absorbing carrier, and sealing to obtain the extract tablet.

Description

The preparation method of the immersion sheet for the treatment of cyclomastopathy
Technical field
The present invention relates to tcm field, particularly relate to a kind of immersion sheet for the treatment of cyclomastopathy and preparation method thereof, can by skin absorb the drug effective ingredient treatment cyclomastopathy.
Background technology
Cyclomastopathy is that cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and newborn lobule degeneration structurally and the growth of Progressive symmetric erythrokeratodermia connective tissue, and its pathogenic factor is mainly due to endocrine hormone imbalance.Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.This sick sickness rate was in the trend risen year by year in the last few years, and the age also more and more becomes younger.About there is the women of 70% ~ 80% to have cyclomastopathy in various degree according to investigations, be more common in the women of 25 ~ 45 years old.
Present general treatment cyclomastopathy can oral XIAOJIN DAN, Mind-easing Powder, 5% potassium iodide, RUKUAIXIAO, RUPIXIAO, Tabellae Asparagini, PINGXIAO PIAN, the spirit of capsule addiction, tamoxifen etc., be singly widespread treatments DeGrain, what have has larger side effect.In addition, still have hormonotherapy, adopt androgen in treating primary disease, use suppression estrogen effect, softening tuberosity, mitigation symptoms, but this treatment likely aggravates between human hormone unbalance, unsuitable conventional application.At present, the immersion sheet of curing mammary gland hyperplasia is not also applied to.
Summary of the invention
An object of the present invention is to solve at least the problems referred to above and/or defect, and the advantage will illustrated at least is below provided.
Another object of the present invention is to provide a kind of preparation method for the treatment of the immersion sheet of cyclomastopathy, effective ingredient can be made fully to be absorbed through skin pore, effectively treat cyclomastopathy.
Other objects with some for achieving the above object, the present invention adopts following technical scheme:
Treat a preparation method for the immersion sheet of cyclomastopathy, comprise the following steps:
Step one, take the crude drug of following weight portion: Radix Bupleuri 13-18, Rhizoma Cyperi 5-7, Pericarpium Citri Reticulatae 5-7, Semen Persicae 8-12, Radix Cyathulae 8-12, Caulis Spatholobi 8-12, Semen Vaccariae 10-15, Medulla Tetrapanacis 8-12, Retinervus Luffae Fructus 10-15, Sargassum 8-10, Thallus Laminariae (Thallus Eckloniae) 8-10, Bulbus Fritillariae Uninbracteatae 5-8 and Concha Ostreae 8-12;
Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution;
Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
Preferably, in the preparation method of the immersion sheet of described treatment cyclomastopathy, crude drug described in step one comprises the component of following weight portion:
Radix Bupleuri 15, Rhizoma Cyperi 6, Pericarpium Citri Reticulatae 6, Semen Persicae 10, Radix Cyathulae 10, Caulis Spatholobi 10, Semen Vaccariae 12, Medulla Tetrapanacis 10, Retinervus Luffae Fructus 12, Sargassum 9, Thallus Laminariae (Thallus Eckloniae) 9, Bulbus Fritillariae Uninbracteatae 6 and Concha Ostreae 10.
Preferably, in the preparation method of the immersion sheet of described treatment cyclomastopathy, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.
Preferably, in the preparation method of the immersion sheet of described treatment cyclomastopathy, in step 2, crude drug is crushed to 50-120 order.
Preferably, in the preparation method of the immersion sheet of described treatment cyclomastopathy, the carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
The present invention at least comprises following beneficial effect: first, and the present invention utilizes the traditional Chinese medical science five elements and dialectical theory, and think that the cause of disease of cyclomastopathy is: depressed emotion, the stagnation of QI is not relaxed, thrombosis, blocking barrier, and knot gathers for core, follows through staying poly-Ruzhong, therefore Ruzhong caking hypertrophy.In the present invention, Radix Bupleuri, vinegar is fried, dispersing the stagnated live-QI to relieve the stagnation of QI; Rhizoma Cyperi, QI regulating by alleviation of mental depression; Pericarpium Citri Reticulatae, regulates the flow of vital energy, invigorates blood circulation; Semen Persicae, blood circulation promoting and blood stasis dispelling, blood stasis dispelling are stagnant; Radix Cyathulae, blood circulation promoting and blood stasis dispelling; Caulis Spatholobi, promoting the circulation of blood of enriching blood, dredge the meridian passage; Semen Vaccariae, invigorates blood circulation, stimulates the menstrual flow, subsides a swelling; Medulla Tetrapanacis, promoting the flow of QI in the collateral by warming the meridian, lactogenesis; Retinervus Luffae Fructus, dredge the meridian passage, detumescence; Sargassum, heat clearing away, hard masses softening and resolving; Thallus Laminariae (Thallus Eckloniae), hard masses softening and resolving; Bulbus Fritillariae Uninbracteatae, heat clearing away eliminating stagnation; Concha Ostreae, hard masses softening and resolving.The present invention, by depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, hard masses softening and resolving, detumescence, makes cyclomastopathy be cured.
Secondly, the present invention is by being adsorbed on water absorption carrier by medicinal liquid, obtain being full of the immersion sheet having ingredient, can patient illness part be attached to, be absorbed the drug effective ingredient by pore, have no side effect, easy to use, and be conducive to the quick absorption of medicine, shorten action time, and improve therapeutic effect.
Part is embodied by explanation below by other advantage of the present invention, target and feature, part also will by research and practice of the present invention by those skilled in the art is understood.
Detailed description of the invention
Below the present invention is elaborated, can implement according to this after consulting this description to make those of ordinary skill in the art.
Treat a preparation method for the immersion sheet of cyclomastopathy, comprise the following steps:
Step one, take the crude drug of following weight portion: Radix Bupleuri 13-18, Rhizoma Cyperi 5-7, Pericarpium Citri Reticulatae 5-7, Semen Persicae 8-12, Radix Cyathulae 8-12, Caulis Spatholobi 8-12, Semen Vaccariae 10-15, Medulla Tetrapanacis 8-12, Retinervus Luffae Fructus 10-15, Sargassum 8-10, Thallus Laminariae (Thallus Eckloniae) 8-10, Bulbus Fritillariae Uninbracteatae 5-8 and Concha Ostreae 8-12;
Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution;
Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
The present invention utilizes the traditional Chinese medical science five elements and dialectical theory, and think that the cause of disease of cyclomastopathy is: depressed emotion, the stagnation of QI is not relaxed, thrombosis, blocking barrier, and knot gathers for core, follows through staying poly-Ruzhong, therefore Ruzhong caking hypertrophy.In the present invention, Radix Bupleuri, vinegar is fried, dispersing the stagnated live-QI to relieve the stagnation of QI; Rhizoma Cyperi, QI regulating by alleviation of mental depression; Pericarpium Citri Reticulatae, regulates the flow of vital energy, invigorates blood circulation; Semen Persicae, blood circulation promoting and blood stasis dispelling, blood stasis dispelling are stagnant; Radix Cyathulae, blood circulation promoting and blood stasis dispelling; Caulis Spatholobi, promoting the circulation of blood of enriching blood, dredge the meridian passage; Semen Vaccariae, invigorates blood circulation, stimulates the menstrual flow, subsides a swelling; Medulla Tetrapanacis, promoting the flow of QI in the collateral by warming the meridian, lactogenesis; Retinervus Luffae Fructus, dredge the meridian passage, detumescence; Sargassum, heat clearing away, hard masses softening and resolving; Thallus Laminariae (Thallus Eckloniae), hard masses softening and resolving; Bulbus Fritillariae Uninbracteatae, heat clearing away eliminating stagnation; Concha Ostreae, hard masses softening and resolving.The present invention, by depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, hard masses softening and resolving, detumescence, makes cyclomastopathy be cured.
The present invention is by being adsorbed on water absorption carrier by medicinal liquid, obtain being full of the immersion sheet having ingredient, patient illness part can be attached to, to be absorbed the drug effective ingredient by pore, have no side effect, easy to use, and be conducive to the quick absorption of medicine, shorten action time, and improve therapeutic effect.
In the crude drug that the present invention is used, also comprise the component of following weight portion: Fructus Akebiae 5-7, Flos Rosae Rugosae 5-7, Squama Manis 4-6, Fructus Forsythiae 8-12.Fructus Akebiae, depressed liver-energy dispersing and QI regulating, eliminating stagnation; Flos Rosae Rugosae, promoting QI circulation for relieving depression and blood dissipating blood stasis; Squama Manis, promoting blood circulation to restore menstrual flow, detumescence; Fructus Forsythiae, detumescence, eliminating stagnation.
In the preparation method of the immersion sheet of described treatment cyclomastopathy, crude drug described in step one comprises the component of following weight portion: Radix Bupleuri 15, Rhizoma Cyperi 6, Pericarpium Citri Reticulatae 6, Semen Persicae 10, Radix Cyathulae 10, Caulis Spatholobi 10, Semen Vaccariae 12, Medulla Tetrapanacis 10, Retinervus Luffae Fructus 12, Sargassum 9, Thallus Laminariae (Thallus Eckloniae) 9, Bulbus Fritillariae Uninbracteatae 6 and Concha Ostreae 10.
In the preparation method of the immersion sheet of described treatment cyclomastopathy, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.
In the preparation method of the immersion sheet of described treatment cyclomastopathy, in step 2, crude drug is crushed to 50-120 order.
In the preparation method of the immersion sheet of described treatment cyclomastopathy, the carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
During use, described immersion sheet is attached at affected part, and to its transferring heat, immersion sheet is heated, reach the effect of hot compress, to promote that effective ingredient absorbs, effective ingredient output speed can be accelerated on the one hand by being heated, heated skin pore is opened on the other hand, and local blood circulation is accelerated, and is conducive to the quick absorption of drug effect, shorten action time, and improve therapeutic effect.Each hot compress time is 60-90 minute, every hot compress in 3-5 hour once, and treatment more than 20 days Be very effective continuously.
Although embodiment of the present invention are open as above, but it is not restricted to listed in description and embodiment utilization, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the general concept that claim and equivalency range limit, the present invention is not limited to specific details.

Claims (5)

1. treat a preparation method for the immersion sheet of cyclomastopathy, it is characterized in that, comprise the following steps:
Step one, take the crude drug of following weight portion: Radix Bupleuri 13-18, Rhizoma Cyperi 5-7, Pericarpium Citri Reticulatae 5-7, Semen Persicae 8-12, Radix Cyathulae 8-12, Caulis Spatholobi 8-12, Semen Vaccariae 10-15, Medulla Tetrapanacis 8-12, Retinervus Luffae Fructus 10-15, Sargassum 8-10, Thallus Laminariae (Thallus Eckloniae) 8-10, Bulbus Fritillariae Uninbracteatae 5-8 and Concha Ostreae 8-12;
Step 2, by taken crude drug pulverize after with ethanol mixing lixiviate, obtain lixiviate stock solution;
Step 3, by lixiviate stock solution purification dilute, obtain lixiviating solution, lixiviating solution be adsorbed onto on water absorption carrier, sealing, obtain described immersion sheet.
2. the preparation method of the immersion sheet for the treatment of cyclomastopathy as claimed in claim 1, it is characterized in that, crude drug described in step one comprises the component of following weight portion:
Radix Bupleuri 15, Rhizoma Cyperi 6, Pericarpium Citri Reticulatae 6, Semen Persicae 10, Radix Cyathulae 10, Caulis Spatholobi 10, Semen Vaccariae 12, Medulla Tetrapanacis 10, Retinervus Luffae Fructus 12, Sargassum 9, Thallus Laminariae (Thallus Eckloniae) 9, Bulbus Fritillariae Uninbracteatae 6 and Concha Ostreae 10.
3. the preparation method of the immersion sheet for the treatment of cyclomastopathy as claimed in claim 1, it is characterized in that, in step 2, concentration of alcohol used is 70-80%; Ethanol consumption is 5-20 times of crude drug volume.
4. the preparation method of the immersion sheet for the treatment of cyclomastopathy as claimed in claim 1, is characterized in that, in step 2, crude drug is crushed to 50-120 order.
5. the preparation method of the immersion sheet for the treatment of cyclomastopathy as claimed in claim 1, it is characterized in that, the carrier of water absorption described in step 3 is cotton, fluffy cotton or water-absorbing resins.
CN201510960267.XA 2015-12-19 2015-12-19 Preparation method of extract tablet for treating hyperplasia of mammary glands Pending CN105477295A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101455808A (en) * 2008-11-11 2009-06-17 路佃俊 External medicine for treating hyperplasia of mammary glands
CN104667171A (en) * 2015-01-28 2015-06-03 慕森 Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine

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CN101455808A (en) * 2008-11-11 2009-06-17 路佃俊 External medicine for treating hyperplasia of mammary glands
CN104667171A (en) * 2015-01-28 2015-06-03 慕森 Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine

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