CN105473130A - 治疗开角型青光眼和高眼压症的药物递送系统和方法 - Google Patents

治疗开角型青光眼和高眼压症的药物递送系统和方法 Download PDF

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Publication number
CN105473130A
CN105473130A CN201380035719.2A CN201380035719A CN105473130A CN 105473130 A CN105473130 A CN 105473130A CN 201380035719 A CN201380035719 A CN 201380035719A CN 105473130 A CN105473130 A CN 105473130A
Authority
CN
China
Prior art keywords
eye
latanoprost
implant
lacrimal
iop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380035719.2A
Other languages
English (en)
Chinese (zh)
Inventor
迪潘克·乌特克赫德
苏珊娜·卡登
郝勇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novelion Therapeutics Inc
Original Assignee
QLT Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by QLT Inc filed Critical QLT Inc
Publication of CN105473130A publication Critical patent/CN105473130A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
CN201380035719.2A 2012-05-03 2013-02-27 治疗开角型青光眼和高眼压症的药物递送系统和方法 Pending CN105473130A (zh)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201261642287P 2012-05-03 2012-05-03
US61/642,287 2012-05-03
US201261644397P 2012-05-08 2012-05-08
US201261644401P 2012-05-08 2012-05-08
US61/644,397 2012-05-08
US61/644,401 2012-05-08
US201261659921P 2012-06-14 2012-06-14
US61/659,921 2012-06-14
US201261680641P 2012-08-07 2012-08-07
US61/680,641 2012-08-07
US201261717615P 2012-10-23 2012-10-23
US61/717,615 2012-10-23
PCT/IB2013/000694 WO2013164671A1 (en) 2012-05-03 2013-02-27 Drug delivery system and methods of treating open angle glaucoma and ocular hypertension

Publications (1)

Publication Number Publication Date
CN105473130A true CN105473130A (zh) 2016-04-06

Family

ID=49514247

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380035719.2A Pending CN105473130A (zh) 2012-05-03 2013-02-27 治疗开角型青光眼和高眼压症的药物递送系统和方法

Country Status (7)

Country Link
EP (1) EP2844224B1 (enExample)
JP (1) JP6213560B2 (enExample)
CN (1) CN105473130A (enExample)
CA (1) CA2872338C (enExample)
HK (1) HK1222810A1 (enExample)
IN (1) IN2014DN09713A (enExample)
WO (1) WO2013164671A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132731A (zh) * 2017-09-07 2020-05-08 光辉疗法公司 维护与异物相关的功能性引流泡的方法、系统和组合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10272040B2 (en) 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106352A1 (en) * 2003-05-30 2006-05-18 Katsuaki Kurihashi Lacrimal punctum plug
US20090280158A1 (en) * 2008-05-09 2009-11-12 Qlt Plug Delivery, Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
US20100274204A1 (en) * 2009-02-23 2010-10-28 Qlt Plug Delivery, Inc. Lacrimal implants and related methods

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US3321108A (en) 1965-11-26 1967-05-23 William E Bowe Printing ink dispenser
US3681608A (en) 1971-03-17 1972-08-01 Us Navy Laser beam receiver having a high signal to noise ratio
US4281654A (en) 1980-04-07 1981-08-04 Alza Corporation Drug delivery system for controlled ocular therapy
US4952581A (en) 1987-04-03 1990-08-28 The Trustees Of Columbia University In The City Of New York Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure
US4936008A (en) 1988-05-09 1990-06-26 Teledyne Mec Laser striping method for assembling TWT
US4934708A (en) 1988-05-20 1990-06-19 Kolkind Gerald L Family quiz board game
US5296504A (en) 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5259508A (en) 1992-08-27 1993-11-09 Beckerman Stephen M Protective shipping package
ES2105333T3 (es) 1992-10-13 1997-10-16 Alcon Lab Inc Combinaciones de prostaglandinas y derivados de clonidina para el tratamiento del glaucoma.
US6622308B1 (en) 1999-03-23 2003-09-16 Scientific-Atlanta, Inc. Automatic digital television (DTV) bypass for a CATV converter using a CATV tuner
US6534693B2 (en) 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US7300364B2 (en) 2004-02-06 2007-11-27 Acushnet Company Multi-layer golf ball having velocity gradient from faster center to slower cover
US20040170685A1 (en) 2003-02-26 2004-09-02 Medivas, Llc Bioactive stents and methods for use thereof
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
US20050129731A1 (en) 2003-11-03 2005-06-16 Roland Horres Biocompatible, biostable coating of medical surfaces
MXPA06007678A (es) 2004-01-05 2006-09-01 Nicox Sa Nitroxiderivados de prostaglandinas.
US20050232972A1 (en) * 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
WO2006014434A2 (en) 2004-07-02 2006-02-09 Eliot Lazar Treatment medium delivery device and methods for delivery
KR101062796B1 (ko) 2006-03-31 2011-09-06 큐엘티 인코포레이티드 약물 요법을 위한 비루관 배출계 임플란트
CN101616640B (zh) * 2006-12-26 2013-02-27 Qlt插入传输公司 用于抑制视觉缺陷的给药植入体
UY30883A1 (es) 2007-01-31 2008-05-31 Alcon Res Tapones punctales y metodos de liberacion de agentes terapeuticos
BRPI0817074A2 (pt) 2007-09-07 2015-03-24 Qlt Plug Delivery Inc Aparelho, método para tratar uma desordem ocular, dispositivo de detecção e sistema de detecção
CN101984745B (zh) 2007-09-07 2013-08-14 Qlt股份有限公司 用于持续释放治疗药物的药物核心
CA2698574A1 (en) 2007-09-07 2009-03-19 Qlt Plug Delivery, Inc. Insertion and extraction tools for lacrimal implants
ES2732555T3 (es) 2007-09-07 2019-11-25 Mati Therapeutics Inc Implantes lagrimales y métodos relacionados
AU2010206610A1 (en) 2009-01-23 2011-08-11 Qlt Inc. Sustained released delivery of one or more agents
US20120245539A1 (en) 2009-11-27 2012-09-27 Qlt Inc. Lacrimal implants including split and insertable drug core

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106352A1 (en) * 2003-05-30 2006-05-18 Katsuaki Kurihashi Lacrimal punctum plug
US20090280158A1 (en) * 2008-05-09 2009-11-12 Qlt Plug Delivery, Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
US20100274204A1 (en) * 2009-02-23 2010-10-28 Qlt Plug Delivery, Inc. Lacrimal implants and related methods

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132731A (zh) * 2017-09-07 2020-05-08 光辉疗法公司 维护与异物相关的功能性引流泡的方法、系统和组合物

Also Published As

Publication number Publication date
WO2013164671A1 (en) 2013-11-07
HK1222810A1 (zh) 2017-07-14
EP2844224A4 (en) 2016-02-24
CA2872338A1 (en) 2013-11-07
JP6213560B2 (ja) 2017-10-18
EP2844224A1 (en) 2015-03-11
IN2014DN09713A (enExample) 2015-07-31
JP2015520628A (ja) 2015-07-23
CA2872338C (en) 2021-09-14
EP2844224B1 (en) 2018-04-11

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